2A7OA

Solution structure of the hset2/hypb sri domain
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
100
structure length
100
Chain Sequence
TSSELAKKSKEVFRKEMSQFIVQCLNPYRKPDCKVGRITTTEDFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQKFGAVYKPKEDT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the Set2 Rpb1 interacting domain of human Set2 and its interaction with the hyperphosphorylated C-terminal domain of Rpb1
pubmed doi rcsb
molecule tags Transcription
source organism Homo sapiens
molecule keywords Huntingtin interacting protein B
total genus 38
structure length 100
sequence length 100
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2005-07-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08236 SRI SRI (Set2 Rpb1 interacting) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1740.100 Mainly Alpha Orthogonal Bundle Rna Polymerase Sigma Factor; Chain: A Rna Polymerase Sigma Factor; Chain: A 2a7oA00
2A7OA 2C5ZA
chains in the Genus database with same CATH superfamily
3B7RL 4OOEA 5DYFA 5JMPA 4Y6RA 2C5ZA 1H19A 2O7GA 2PUSA 3CXBA 4RSYA 4XMTA 4Y6SA 4XMVA 2PGGA 4XN1A 3FH5A 4ZW8A 2A7OA 3FTYA 4ZX5A 3B34A 3ZI0A 4RCVA 4ZN6A 2R70A 4KP7A 4QIRA 3CZKA 3IIEA 2JD0A 3ANLA 4A03A 4X2UA 1SQMA 2Y1DA 3R0IA 3CHSA 3CZGA 2C82A 5JO0A 2DQ6A 3FH8A 3FUJA 2JCVA 3JT1A 2MAPA 1OR7A 3A14A 4ZQTA 3U9WA 3PUUA 4OOFA 4QMEA 3CHQA 1ONNA 4K5MA 4K5LA 4ZW7A 3CZLA 2HPTA 3WQSB 4AYSA 4Q4IA 3FTWA 4XMXA 1T1SA 1MW0A 2Y1CA 2VLAA 2Y1GA 3FTSA 4Y6PA 1Q0HA 2RJIA 2JD1A 4R7LA 3T8VA 4QPEA 4ZX6A 3AUAA 4GAAA 4LUPA 3FUIA 3FH7A 3FUFA 4BKXA 1MW1A 4PVBA 3AU9A 4FLRA 4K5NA 5HNHA 1R0LA 4XN8A 4XNDA 4XN7A 4XO5A 3ZHXA 2JV7A 4K5PA 3B7UX 3HW2A 2HPOA 3UEQA 4XMWA 3FU6A 2ZXGA 5EV7A 1SC5A 3Q44A 4ZQHA 1HS6A 2B61A 4XMZA 4R5VA 3VVLA 4FLSA 1ONPA 3FTZA 3FU0A 4ZQGA 1ZS2A 2FFLA 3B2PA 2R72A 4ZX4A 2EGHA 2WZFA 1Q0LA 4XMUA 3B2XA 3B37A 1G5AA 2XPYA 3T0YA 3CHRA 5JBIA 3KEDA 4AR9A 3EBGA 3RC3A 4GAEA 3AU8A 4XN2A 2VJ8A 5DLLA 2JCXA 4L2LA 4RVBA 3B7TA 3UCQA 4Y67A 1H3LA 5JC1A 4XN5A 3FUHA 4QHPA 1Q0QA 3B3BA 3FUMA 3CHPA 3Q43A 1MVYA 2PL5A 3A06A 3FU3A 4NQWA 2QJ1A 4FLOA 4J3BA 3FHEA 1JGIA 4XNBA 1GW6A 2QVWA 4XO3A 4AICA 3FULA 4AR1A 5JMWA 3JSZA 4ARFA 4MKTA 4Q4EA 4XN4A 4QUOA 4PU2A 4K5OA 5HNFA 2MAOA 4FCAA 2XQ0A 4XO4A 1X3ZA 3FUDA 4ZW6A 1T1RA 4ZW5A 5JNLA 2DQMA 1R0KA 4ZW3A 1MW3A 2JD2A 2JCYA 5HLTA 5FWQA 3CIAA 4ZQEA 3CHOA 3EBIA 4AR8A 2GTQA 4PW4A 1JVSA 3RASA 3FUKA 4ZX3A 2WZGA 3VVMA 4XNAA 2Y1EA 3ANNA 2WPGA 4MS6A 4R5XA 4DPRA 1MW2A 1S46A 3B7SA 3FUEA 1JG9A 5AENA 1K5HA 3ZHYA 4R5TA 4CXFA 3ANMA 3FTXA 5DULA 4JNDA 3CZEA 1SG7A 3UERA 2R59A 4ZQFA 5JAZA 1ONOA 3WQRA 3FTVA 3FTUA 3FU5A 4XN9A 3EBHA 3FUNA 3ZHZA 3WQQA 1RP3A 2Y1FA 2XPZA 3QJXA 3RC8A 1X3WA 5BPPA 4FLQA
chains in the Genus database with same CATH topology
3B7RL 4OOEA 5DYFA 5JMPA 4Y6RA 2C5ZA 1H19A 2O7GA 2PUSA 4RSYA 4XMTA 4Y6SA 4XMVA 2PGGA 4XN1A 3FH5A 4ZW8A 2A7OA 3FTYA 4ZX5A 3B34A 3ZI0A 4RCVA 4ZN6A 2R70A 4KP7A 4QIRA 3CZKA 3IIEA 2JD0A 3ANLA 4A03A 4X2UA 1SQMA 2Y1DA 3R0IA 3CHSA 3CZGA 2C82A 5JO0A 2DQ6A 3FH8A 3FUJA 2JCVA 3JT1A 2MAPA 1OR7A 3A14A 4ZQTA 3U9WA 3PUUA 4OOFA 4QMEA 3CHQA 1ONNA 4K5MA 4K5LA 4ZW7A 3CZLA 2HPTA 3WQSB 4AYSA 4Q4IA 3FTWA 4XMXA 1T1SA 1MW0A 2Y1CA 2VLAA 2Y1GA 3FTSA 4Y6PA 1Q0HA 2RJIA 2JD1A 4R7LA 3T8VA 4QPEA 4ZX6A 3AUAA 4GAAA 4LUPA 3FUIA 3FH7A 3FUFA 4BKXA 1MW1A 4PVBA 3AU9A 4FLRA 4K5NA 5HNHA 1R0LA 4XN8A 4XNDA 4XN7A 4XO5A 3ZHXA 2JV7A 4K5PA 3B7UX 3UEQA 2HPOA 4XMWA 3FU6A 2ZXGA 5EV7A 1SC5A 3Q44A 4ZQHA 1HS6A 2B61A 4XMZA 4R5VA 3VVLA 4FLSA 1ONPA 3FTZA 3FU0A 4ZQGA 1ZS2A 2FFLA 3B2PA 2R72A 4ZX4A 2EGHA 2WZFA 1Q0LA 4XMUA 3B2XA 3B37A 1G5AA 2XPYA 3T0YA 3CHRA 5JBIA 3KEDA 4AR9A 3EBGA 3RC3A 4GAEA 3AU8A 4XN2A 2VJ8A 5DLLA 2JCXA 4L2LA 4RVBA 3B7TA 3UCQA 4Y67A 1H3LA 5JC1A 4XN5A 3FUHA 4QHPA 1Q0QA 3B3BA 3FUMA 3CHPA 3Q43A 1MVYA 2PL5A 3A06A 3FU3A 4NQWA 2QJ1A 4FLOA 4J3BA 3FHEA 1JGIA 4XNBA 1GW6A 2QVWA 4XO3A 4AICA 3FULA 4AR1A 5JMWA 3JSZA 4ARFA 4MKTA 4Q4EA 4XN4A 4QUOA 4PU2A 4K5OA 5HNFA 2MAOA 4FCAA 2XQ0A 4XO4A 1X3ZA 3FUDA 4ZW6A 1T1RA 4ZW5A 5JNLA 2DQMA 1R0KA 4ZW3A 1MW3A 2JD2A 2JCYA 5HLTA 5FWQA 3CIAA 4ZQEA 3CHOA 3EBIA 4AR8A 2GTQA 4PW4A 1JVSA 3RASA 3FUKA 4ZX3A 2WZGA 3VVMA 4XNAA 2Y1EA 3ANNA 2WPGA 4MS6A 4R5XA 4DPRA 1MW2A 1S46A 3B7SA 3FUEA 1JG9A 5AENA 1K5HA 3ZHYA 4R5TA 4CXFA 3ANMA 3FTXA 5DULA 4JNDA 3CZEA 1SG7A 3UERA 2R59A 4ZQFA 5JAZA 1ONOA 3WQRA 3FTVA 3FTUA 3FU5A 4XN9A 3EBHA 3FUNA 3ZHZA 3WQQA 1RP3A 2Y1FA 2XPZA 3QJXA 3RC8A 1X3WA 5BPPA 4FLQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2A7O A;  2C5Z A; 
#chains in the Genus database with same CATH topology
 3B7R L;  4OOE A;  5DYF A;  5JMP A;  4Y6R A;  2C5Z A;  1H19 A;  2O7G A;  2PUS A;  3CXB A;  4RSY A;  4XMT A;  4Y6S A;  4XMV A;  2PGG A;  4XN1 A;  3FH5 A;  4ZW8 A;  2A7O A;  3FTY A;  4ZX5 A;  3B34 A;  3ZI0 A;  4RCV A;  4ZN6 A;  2R70 A;  4KP7 A;  4QIR A;  3CZK A;  3IIE A;  2JD0 A;  3ANL A;  4A03 A;  4X2U A;  1SQM A;  2Y1D A;  3R0I A;  3CHS A;  3CZG A;  2C82 A;  5JO0 A;  2DQ6 A;  3FH8 A;  3FUJ A;  2JCV A;  3JT1 A;  2MAP A;  1OR7 A;  3A14 A;  4ZQT A;  3U9W A;  3PUU A;  4OOF A;  4QME A;  3CHQ A;  1ONN A;  4K5M A;  4K5L A;  4ZW7 A;  3CZL A;  2HPT A;  3WQS B;  4AYS A;  4Q4I A;  3FTW A;  4XMX A;  1T1S A;  1MW0 A;  2Y1C A;  2VLA A;  2Y1G A;  3FTS A;  4Y6P A;  1Q0H A;  2RJI A;  2JD1 A;  4R7L A;  3T8V A;  4QPE A;  4ZX6 A;  3AUA A;  4GAA A;  4LUP A;  3FUI A;  3FH7 A;  3FUF A;  4BKX A;  1MW1 A;  4PVB A;  3AU9 A;  4FLR A;  4K5N A;  5HNH A;  1R0L A;  4XN8 A;  4XND A;  4XN7 A;  4XO5 A;  3ZHX A;  2JV7 A;  4K5P A;  3B7U X;  3HW2 A;  2HPO A;  3UEQ A;  4XMW A;  3FU6 A;  2ZXG A;  5EV7 A;  1SC5 A;  3Q44 A;  4ZQH A;  1HS6 A;  2B61 A;  4XMZ A;  4R5V A;  3VVL A;  4FLS A;  1ONP A;  3FTZ A;  3FU0 A;  4ZQG A;  1ZS2 A;  2FFL A;  3B2P A;  2R72 A;  4ZX4 A;  2EGH A;  2WZF A;  1Q0L A;  4XMU A;  3B2X A;  3B37 A;  1G5A A;  2XPY A;  3T0Y A;  3CHR A;  5JBI A;  3KED A;  4AR9 A;  3EBG A;  3RC3 A;  4GAE A;  3AU8 A;  4XN2 A;  2VJ8 A;  5DLL A;  2JCX A;  4L2L A;  4RVB A;  3B7T A;  3UCQ A;  4Y67 A;  1H3L A;  5JC1 A;  4XN5 A;  3FUH A;  4QHP A;  1Q0Q A;  3B3B A;  3FUM A;  3CHP A;  3Q43 A;  1MVY A;  2PL5 A;  3A06 A;  3FU3 A;  4NQW A;  2QJ1 A;  4FLO A;  4J3B A;  3FHE A;  1JGI A;  4XNB A;  1GW6 A;  2QVW A;  4XO3 A;  4AIC A;  3FUL A;  4AR1 A;  5JMW A;  3JSZ A;  4ARF A;  4MKT A;  4Q4E A;  4XN4 A;  4QUO A;  4PU2 A;  4K5O A;  5HNF A;  2MAO A;  4FCA A;  2XQ0 A;  4XO4 A;  1X3Z A;  3FUD A;  4ZW6 A;  1T1R A;  4ZW5 A;  5JNL A;  2DQM A;  1R0K A;  4ZW3 A;  1MW3 A;  2JD2 A;  2JCY A;  5HLT A;  5FWQ A;  3CIA A;  4ZQE A;  3CHO A;  3EBI A;  4AR8 A;  2GTQ A;  4PW4 A;  1JVS A;  3RAS A;  3FUK A;  4ZX3 A;  2WZG A;  3VVM A;  4XNA A;  2Y1E A;  3ANN A;  2WPG A;  4MS6 A;  4R5X A;  4DPR A;  1MW2 A;  1S46 A;  3B7S A;  3FUE A;  1JG9 A;  5AEN A;  1K5H A;  3ZHY A;  4R5T A;  4CXF A;  3ANM A;  3FTX A;  5DUL A;  4JND A;  3CZE A;  1SG7 A;  3UER A;  2R59 A;  4ZQF A;  5JAZ A;  1ONO A;  3WQR A;  3FTV A;  3FTU A;  3FU5 A;  4XN9 A;  3EBH A;  3FUN A;  3ZHZ A;  3WQQ A;  1RP3 A;  2Y1F A;  2XPZ A;  3QJX A;  3RC8 A;  1X3W A;  5BPP A;  4FLQ A; 
#chains in the Genus database with same CATH homology
 3B7R L;  4OOE A;  5DYF A;  5JMP A;  4Y6R A;  2C5Z A;  1H19 A;  2O7G A;  2PUS A;  4RSY A;  4XMT A;  4Y6S A;  4XMV A;  2PGG A;  4XN1 A;  3FH5 A;  4ZW8 A;  2A7O A;  3FTY A;  4ZX5 A;  3B34 A;  3ZI0 A;  4RCV A;  4ZN6 A;  2R70 A;  4KP7 A;  4QIR A;  3CZK A;  3IIE A;  2JD0 A;  3ANL A;  4A03 A;  4X2U A;  1SQM A;  2Y1D A;  3R0I A;  3CHS A;  3CZG A;  2C82 A;  5JO0 A;  2DQ6 A;  3FH8 A;  3FUJ A;  2JCV A;  3JT1 A;  2MAP A;  1OR7 A;  3A14 A;  4ZQT A;  3U9W A;  3PUU A;  4OOF A;  4QME A;  3CHQ A;  1ONN A;  4K5M A;  4K5L A;  4ZW7 A;  3CZL A;  2HPT A;  3WQS B;  4AYS A;  4Q4I A;  3FTW A;  4XMX A;  1T1S A;  1MW0 A;  2Y1C A;  2VLA A;  2Y1G A;  3FTS A;  4Y6P A;  1Q0H A;  2RJI A;  2JD1 A;  4R7L A;  3T8V A;  4QPE A;  4ZX6 A;  3AUA A;  4GAA A;  4LUP A;  3FUI A;  3FH7 A;  3FUF A;  4BKX A;  1MW1 A;  4PVB A;  3AU9 A;  4FLR A;  4K5N A;  5HNH A;  1R0L A;  4XN8 A;  4XND A;  4XN7 A;  4XO5 A;  3ZHX A;  2JV7 A;  4K5P A;  3B7U X;  3UEQ A;  2HPO A;  4XMW A;  3FU6 A;  2ZXG A;  5EV7 A;  1SC5 A;  3Q44 A;  4ZQH A;  1HS6 A;  2B61 A;  4XMZ A;  4R5V A;  3VVL A;  4FLS A;  1ONP A;  3FTZ A;  3FU0 A;  4ZQG A;  1ZS2 A;  2FFL A;  3B2P A;  2R72 A;  4ZX4 A;  2EGH A;  2WZF A;  1Q0L A;  4XMU A;  3B2X A;  3B37 A;  1G5A A;  2XPY A;  3T0Y A;  3CHR A;  5JBI A;  3KED A;  4AR9 A;  3EBG A;  3RC3 A;  4GAE A;  3AU8 A;  4XN2 A;  2VJ8 A;  5DLL A;  2JCX A;  4L2L A;  4RVB A;  3B7T A;  3UCQ A;  4Y67 A;  1H3L A;  5JC1 A;  4XN5 A;  3FUH A;  4QHP A;  1Q0Q A;  3B3B A;  3FUM A;  3CHP A;  3Q43 A;  1MVY A;  2PL5 A;  3A06 A;  3FU3 A;  4NQW A;  2QJ1 A;  4FLO A;  4J3B A;  3FHE A;  1JGI A;  4XNB A;  1GW6 A;  2QVW A;  4XO3 A;  4AIC A;  3FUL A;  4AR1 A;  5JMW A;  3JSZ A;  4ARF A;  4MKT A;  4Q4E A;  4XN4 A;  4QUO A;  4PU2 A;  4K5O A;  5HNF A;  2MAO A;  4FCA A;  2XQ0 A;  4XO4 A;  1X3Z A;  3FUD A;  4ZW6 A;  1T1R A;  4ZW5 A;  5JNL A;  2DQM A;  1R0K A;  4ZW3 A;  1MW3 A;  2JD2 A;  2JCY A;  5HLT A;  5FWQ A;  3CIA A;  4ZQE A;  3CHO A;  3EBI A;  4AR8 A;  2GTQ A;  4PW4 A;  1JVS A;  3RAS A;  3FUK A;  4ZX3 A;  2WZG A;  3VVM A;  4XNA A;  2Y1E A;  3ANN A;  2WPG A;  4MS6 A;  4R5X A;  4DPR A;  1MW2 A;  1S46 A;  3B7S A;  3FUE A;  1JG9 A;  5AEN A;  1K5H A;  3ZHY A;  4R5T A;  4CXF A;  3ANM A;  3FTX A;  5DUL A;  4JND A;  3CZE A;  1SG7 A;  3UER A;  2R59 A;  4ZQF A;  5JAZ A;  1ONO A;  3WQR A;  3FTV A;  3FTU A;  3FU5 A;  4XN9 A;  3EBH A;  3FUN A;  3ZHZ A;  3WQQ A;  1RP3 A;  2Y1F A;  2XPZ A;  3QJX A;  3RC8 A;  1X3W A;  5BPP A;  4FLQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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