2A7OA

Solution structure of the hset2/hypb sri domain
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
100
structure length
100
Chain Sequence
TSSELAKKSKEVFRKEMSQFIVQCLNPYRKPDCKVGRITTTEDFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQKFGAVYKPKEDT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the Set2 Rpb1 interacting domain of human Set2 and its interaction with the hyperphosphorylated C-terminal domain of Rpb1
pubmed doi rcsb
molecule tags Transcription
source organism Homo sapiens
molecule keywords Huntingtin interacting protein B
total genus 38
structure length 100
sequence length 100
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2005-07-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08236 SRI SRI (Set2 Rpb1 interacting) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1740.100 Mainly Alpha Orthogonal Bundle Rna Polymerase Sigma Factor; Chain: A Rna Polymerase Sigma Factor; Chain: A 2a7oA00
2A7OA 2C5ZA
chains in the Genus database with same CATH superfamily
4DPRA 4LUPA 3QJXA 4XMZA 4QUOA 5EV7A 1S46A 3Q44A 4K5NA 2JCXA 4XMVA 4ZQEA 4AYSA 4ZQTA 5JAZA 4XNBA 4RSYA 1ONOA 3U9WA 2MAOA 4R5XA 4BKXA 3FUDA 4FLRA 3FTUA 1GW6A 1SC5A 1MW0A 3FHEA 5JNLA 1JVSA 3R0IA 4FCAA 3B7SA 4Y67A 4XO3A 4OOEA 4ZW8A 3RASA 3ZHZA 5DULA 3CZKA 3FUJA 2Y1CA 4QHPA 4Y6SA 4ZX6A 1ONNA 2R72A 3EBHA 1X3ZA 3ANMA 4ZW3A 4Y6PA 3AU8A 3CHQA 3ANNA 3FTSA 3CZEA 4R5TA 3B2XA 4R5VA 5DLLA 4ZW5A 3FUNA 4QIRA 4Q4IA 1T1RA 2PGGA 2ZXGA 4ZQFA 3AU9A 1ZS2A 2R70A 3EBIA 1JG9A 3FUHA 3IIEA 3T0YA 4A03A 3VVMA 2Y1EA 2RJIA 3A14A 2B61A 2A7OA 3CXBA 2GTQA 3FH7A 4FLQA 3RC3A 4RVBA 2DQ6A 4PVBA 3B3BA 4MKTA 3RC8A 2XQ0A 4XO4A 4PU2A 3FU6A 3T8VA 3B2PA 3UCQA 1MW2A 1Q0HA 4XNDA 2VJ8A 4Q4EA 3B37A 3CHPA 1Q0QA 4K5PA 4ZQGA 4ZX4A 4R7LA 4XMTA 2JD1A 3VVLA 5JC1A 1OR7A 2Y1DA 4XN4A 4ZN6A 2R59A 3Q43A 3UEQA 3WQQA 3JT1A 3CZLA 3FTVA 4L2LA 4KP7A 2HPOA 5HLTA 3B7RL 1MW3A 4CXFA 1G5AA 1R0KA 3FUEA 2C5ZA 3FH5A 4GAEA 1MW1A 1MVYA 3FUKA 3HW2A 4K5OA 2Y1GA 4XO5A 2XPZA 3AUAA 3FTXA 4ZQHA 2EGHA 3ZHXA 1SQMA 1R0LA 2JCVA 4XMXA 3FU0A 2HPTA 3FU3A 3FULA 5JO0A 1K5HA 3A06A 4AR1A 1Q0LA 3FTZA 2JD2A 3FU5A 4XMUA 3B7UX 3FTYA 4XNAA 2DQMA 4JNDA 3B34A 4QPEA 5FWQA 4FLSA 3FUIA 4X2UA 5JMPA 4GAAA 2PUSA 4ZX5A 4XMWA 2WZFA 2WZGA 3CHSA 4ARFA 4MS6A 3WQSB 3CIAA 2VLAA 1H19A 3CHRA 3CHOA 1T1SA 4QMEA 4PW4A 4Y6RA 4XN7A 4NQWA 4K5LA 4ZW6A 4K5MA 5HNFA 2C82A 2JD0A 1JGIA 1X3WA 3EBGA 4FLOA 3UERA 3KEDA 2JV7A 2WPGA 2QJ1A 2Y1FA 2FFLA 1ONPA 4AR8A 1H3LA 4XN8A 3FH8A 4OOFA 4RCVA 4XN1A 1SG7A 2MAPA 2JCYA 3JSZA 1HS6A 4AR9A 3FTWA 3FUFA 4ZW7A 3ZHYA 4XN9A 5DYFA 3WQRA 2XPYA 4J3BA 3B7TA 2O7GA 3PUUA 5HNHA 3CZGA 4XN2A 5AENA 3FUMA 5JMWA 5BPPA 5JBIA 4XN5A 4AICA 3ANLA 1RP3A 4ZX3A 2PL5A 2QVWA 3ZI0A
chains in the Genus database with same CATH topology
4DPRA 4LUPA 3QJXA 4XMZA 4QUOA 5EV7A 1S46A 3Q44A 4K5NA 2JCXA 4XMVA 4ZQEA 4AYSA 4ZQTA 5JAZA 4XNBA 4RSYA 1ONOA 3U9WA 2MAOA 4R5XA 4BKXA 3FUDA 4FLRA 3FTUA 1GW6A 1SC5A 1MW0A 3FHEA 5JNLA 1JVSA 3R0IA 4FCAA 3B7SA 4Y67A 4XO3A 4OOEA 4ZW8A 3RASA 3ZHZA 5DULA 3CZKA 3FUJA 2Y1CA 4QHPA 4Y6SA 4ZX6A 1ONNA 2R72A 3EBHA 1X3ZA 3ANMA 4ZW3A 4Y6PA 3AU8A 3CHQA 3ANNA 3FTSA 3CZEA 4R5TA 3B2XA 4R5VA 5DLLA 4ZW5A 3FUNA 4QIRA 4Q4IA 1T1RA 2PGGA 2ZXGA 4ZQFA 3AU9A 1ZS2A 2R70A 3EBIA 1JG9A 3FUHA 3IIEA 3T0YA 4A03A 3VVMA 2Y1EA 2RJIA 3A14A 2B61A 2A7OA 3FH7A 2GTQA 4FLQA 3RC3A 3RC8A 4RVBA 2DQ6A 4PVBA 3B3BA 4MKTA 2XQ0A 4XO4A 4PU2A 3FU6A 3T8VA 3B2PA 3UCQA 1MW2A 1Q0HA 4XNDA 2VJ8A 4Q4EA 3B37A 3CHPA 1Q0QA 4K5PA 4ZQGA 4ZX4A 4R7LA 4XMTA 2JD1A 3VVLA 5JC1A 1OR7A 2Y1DA 4XN4A 4ZN6A 2R59A 3Q43A 3UEQA 3WQQA 3JT1A 3CZLA 3FTVA 4L2LA 4KP7A 2HPOA 5HLTA 3B7RL 1MW3A 4CXFA 1G5AA 1R0KA 3FUEA 2C5ZA 3FH5A 4GAEA 1MW1A 1MVYA 3FUKA 4K5OA 2Y1GA 4XO5A 2XPZA 3AUAA 3FTXA 4ZQHA 2EGHA 3ZHXA 1SQMA 1R0LA 2JCVA 4XMXA 3FU0A 2HPTA 3FU3A 3FULA 5JO0A 1K5HA 3A06A 4AR1A 1Q0LA 3FTZA 2JD2A 3FU5A 4XMUA 3B7UX 3FTYA 4XNAA 2DQMA 4JNDA 3B34A 4QPEA 5FWQA 4FLSA 3FUIA 4X2UA 5JMPA 4GAAA 2PUSA 4ZX5A 4XMWA 2WZFA 2WZGA 3CHSA 4ARFA 4MS6A 3WQSB 3CIAA 2VLAA 1H19A 3CHRA 3CHOA 1T1SA 4QMEA 4PW4A 4Y6RA 4XN7A 4NQWA 4K5LA 4ZW6A 4K5MA 5HNFA 2C82A 2JD0A 1JGIA 1X3WA 3EBGA 4FLOA 3UERA 3KEDA 2JV7A 2WPGA 2QJ1A 2Y1FA 2FFLA 1ONPA 4AR8A 1H3LA 4XN8A 3FH8A 4OOFA 4RCVA 4XN1A 1SG7A 2MAPA 2JCYA 3JSZA 1HS6A 4AR9A 3FTWA 3FUFA 4ZW7A 3ZHYA 4XN9A 5DYFA 3WQRA 2XPYA 4J3BA 3B7TA 2O7GA 3PUUA 5HNHA 3CZGA 4XN2A 5AENA 3FUMA 5JMWA 5BPPA 5JBIA 4XN5A 4AICA 3ANLA 1RP3A 4ZX3A 2PL5A 2QVWA 3ZI0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2A7O A;  2C5Z A; 
#chains in the Genus database with same CATH topology
 4DPR A;  4LUP A;  3QJX A;  4XMZ A;  4QUO A;  5EV7 A;  1S46 A;  3Q44 A;  4K5N A;  2JCX A;  4XMV A;  4ZQE A;  4AYS A;  4ZQT A;  5JAZ A;  4XNB A;  4RSY A;  1ONO A;  3U9W A;  2MAO A;  4R5X A;  4BKX A;  3FUD A;  4FLR A;  3FTU A;  1GW6 A;  1SC5 A;  1MW0 A;  3FHE A;  5JNL A;  1JVS A;  3R0I A;  4FCA A;  3B7S A;  4Y67 A;  4XO3 A;  4OOE A;  4ZW8 A;  3RAS A;  3ZHZ A;  5DUL A;  3CZK A;  3FUJ A;  2Y1C A;  4QHP A;  4Y6S A;  4ZX6 A;  1ONN A;  2R72 A;  3EBH A;  1X3Z A;  3ANM A;  4ZW3 A;  4Y6P A;  3AU8 A;  3CHQ A;  3ANN A;  3FTS A;  3CZE A;  4R5T A;  3B2X A;  4R5V A;  5DLL A;  4ZW5 A;  3FUN A;  4QIR A;  4Q4I A;  1T1R A;  2PGG A;  2ZXG A;  4ZQF A;  3AU9 A;  1ZS2 A;  2R70 A;  3EBI A;  1JG9 A;  3FUH A;  3IIE A;  3T0Y A;  4A03 A;  3VVM A;  2Y1E A;  2RJI A;  3A14 A;  2B61 A;  2A7O A;  3CXB A;  2GTQ A;  3FH7 A;  4FLQ A;  3RC3 A;  4RVB A;  2DQ6 A;  4PVB A;  3B3B A;  4MKT A;  3RC8 A;  2XQ0 A;  4XO4 A;  4PU2 A;  3FU6 A;  3T8V A;  3B2P A;  3UCQ A;  1MW2 A;  1Q0H A;  4XND A;  2VJ8 A;  4Q4E A;  3B37 A;  3CHP A;  1Q0Q A;  4K5P A;  4ZQG A;  4ZX4 A;  4R7L A;  4XMT A;  2JD1 A;  3VVL A;  5JC1 A;  1OR7 A;  2Y1D A;  4XN4 A;  4ZN6 A;  2R59 A;  3Q43 A;  3UEQ A;  3WQQ A;  3JT1 A;  3CZL A;  3FTV A;  4L2L A;  4KP7 A;  2HPO A;  5HLT A;  3B7R L;  1MW3 A;  4CXF A;  1G5A A;  1R0K A;  3FUE A;  2C5Z A;  3FH5 A;  4GAE A;  1MW1 A;  1MVY A;  3FUK A;  3HW2 A;  4K5O A;  2Y1G A;  4XO5 A;  2XPZ A;  3AUA A;  3FTX A;  4ZQH A;  2EGH A;  3ZHX A;  1SQM A;  1R0L A;  2JCV A;  4XMX A;  3FU0 A;  2HPT A;  3FU3 A;  3FUL A;  5JO0 A;  1K5H A;  3A06 A;  4AR1 A;  1Q0L A;  3FTZ A;  2JD2 A;  3FU5 A;  4XMU A;  3B7U X;  3FTY A;  4XNA A;  2DQM A;  4JND A;  3B34 A;  4QPE A;  5FWQ A;  4FLS A;  3FUI A;  4X2U A;  5JMP A;  4GAA A;  2PUS A;  4ZX5 A;  4XMW A;  2WZF A;  2WZG A;  3CHS A;  4ARF A;  4MS6 A;  3WQS B;  3CIA A;  2VLA A;  1H19 A;  3CHR A;  3CHO A;  1T1S A;  4QME A;  4PW4 A;  4Y6R A;  4XN7 A;  4NQW A;  4K5L A;  4ZW6 A;  4K5M A;  5HNF A;  2C82 A;  2JD0 A;  1JGI A;  1X3W A;  3EBG A;  4FLO A;  3UER A;  3KED A;  2JV7 A;  2WPG A;  2QJ1 A;  2Y1F A;  2FFL A;  1ONP A;  4AR8 A;  1H3L A;  4XN8 A;  3FH8 A;  4OOF A;  4RCV A;  4XN1 A;  1SG7 A;  2MAP A;  2JCY A;  3JSZ A;  1HS6 A;  4AR9 A;  3FTW A;  3FUF A;  4ZW7 A;  3ZHY A;  4XN9 A;  5DYF A;  3WQR A;  2XPY A;  4J3B A;  3B7T A;  2O7G A;  3PUU A;  5HNH A;  3CZG A;  4XN2 A;  5AEN A;  3FUM A;  5JMW A;  5BPP A;  5JBI A;  4XN5 A;  4AIC A;  3ANL A;  1RP3 A;  4ZX3 A;  2PL5 A;  2QVW A;  3ZI0 A; 
#chains in the Genus database with same CATH homology
 4DPR A;  4LUP A;  3QJX A;  4XMZ A;  4QUO A;  5EV7 A;  1S46 A;  3Q44 A;  4K5N A;  2JCX A;  4XMV A;  4ZQE A;  4AYS A;  4ZQT A;  5JAZ A;  4XNB A;  4RSY A;  1ONO A;  3U9W A;  2MAO A;  4R5X A;  4BKX A;  3FUD A;  4FLR A;  3FTU A;  1GW6 A;  1SC5 A;  1MW0 A;  3FHE A;  5JNL A;  1JVS A;  3R0I A;  4FCA A;  3B7S A;  4Y67 A;  4XO3 A;  4OOE A;  4ZW8 A;  3RAS A;  3ZHZ A;  5DUL A;  3CZK A;  3FUJ A;  2Y1C A;  4QHP A;  4Y6S A;  4ZX6 A;  1ONN A;  2R72 A;  3EBH A;  1X3Z A;  3ANM A;  4ZW3 A;  4Y6P A;  3AU8 A;  3CHQ A;  3ANN A;  3FTS A;  3CZE A;  4R5T A;  3B2X A;  4R5V A;  5DLL A;  4ZW5 A;  3FUN A;  4QIR A;  4Q4I A;  1T1R A;  2PGG A;  2ZXG A;  4ZQF A;  3AU9 A;  1ZS2 A;  2R70 A;  3EBI A;  1JG9 A;  3FUH A;  3IIE A;  3T0Y A;  4A03 A;  3VVM A;  2Y1E A;  2RJI A;  3A14 A;  2B61 A;  2A7O A;  3FH7 A;  2GTQ A;  4FLQ A;  3RC3 A;  3RC8 A;  4RVB A;  2DQ6 A;  4PVB A;  3B3B A;  4MKT A;  2XQ0 A;  4XO4 A;  4PU2 A;  3FU6 A;  3T8V A;  3B2P A;  3UCQ A;  1MW2 A;  1Q0H A;  4XND A;  2VJ8 A;  4Q4E A;  3B37 A;  3CHP A;  1Q0Q A;  4K5P A;  4ZQG A;  4ZX4 A;  4R7L A;  4XMT A;  2JD1 A;  3VVL A;  5JC1 A;  1OR7 A;  2Y1D A;  4XN4 A;  4ZN6 A;  2R59 A;  3Q43 A;  3UEQ A;  3WQQ A;  3JT1 A;  3CZL A;  3FTV A;  4L2L A;  4KP7 A;  2HPO A;  5HLT A;  3B7R L;  1MW3 A;  4CXF A;  1G5A A;  1R0K A;  3FUE A;  2C5Z A;  3FH5 A;  4GAE A;  1MW1 A;  1MVY A;  3FUK A;  4K5O A;  2Y1G A;  4XO5 A;  2XPZ A;  3AUA A;  3FTX A;  4ZQH A;  2EGH A;  3ZHX A;  1SQM A;  1R0L A;  2JCV A;  4XMX A;  3FU0 A;  2HPT A;  3FU3 A;  3FUL A;  5JO0 A;  1K5H A;  3A06 A;  4AR1 A;  1Q0L A;  3FTZ A;  2JD2 A;  3FU5 A;  4XMU A;  3B7U X;  3FTY A;  4XNA A;  2DQM A;  4JND A;  3B34 A;  4QPE A;  5FWQ A;  4FLS A;  3FUI A;  4X2U A;  5JMP A;  4GAA A;  2PUS A;  4ZX5 A;  4XMW A;  2WZF A;  2WZG A;  3CHS A;  4ARF A;  4MS6 A;  3WQS B;  3CIA A;  2VLA A;  1H19 A;  3CHR A;  3CHO A;  1T1S A;  4QME A;  4PW4 A;  4Y6R A;  4XN7 A;  4NQW A;  4K5L A;  4ZW6 A;  4K5M A;  5HNF A;  2C82 A;  2JD0 A;  1JGI A;  1X3W A;  3EBG A;  4FLO A;  3UER A;  3KED A;  2JV7 A;  2WPG A;  2QJ1 A;  2Y1F A;  2FFL A;  1ONP A;  4AR8 A;  1H3L A;  4XN8 A;  3FH8 A;  4OOF A;  4RCV A;  4XN1 A;  1SG7 A;  2MAP A;  2JCY A;  3JSZ A;  1HS6 A;  4AR9 A;  3FTW A;  3FUF A;  4ZW7 A;  3ZHY A;  4XN9 A;  5DYF A;  3WQR A;  2XPY A;  4J3B A;  3B7T A;  2O7G A;  3PUU A;  5HNH A;  3CZG A;  4XN2 A;  5AEN A;  3FUM A;  5JMW A;  5BPP A;  5JBI A;  4XN5 A;  4AIC A;  3ANL A;  1RP3 A;  4ZX3 A;  2PL5 A;  2QVW A;  3ZI0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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