2AVT | Genus

Total Genus 92

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	92
sequence length	377
structure length	372
Chain Sequence	MIQFSINRTLFIHALNTTKRAISTKNAIPILSSIKIEVTSTGVTLTGSNGQISIENTIPVGLLITSPGAILLEASFFINIISSLPDISINVKEIEQHQVVLTSGKSEITLKGKDVDQYPRLQEVSTENPLILKTKLLKSIIAETAFAASLQESRPILTGVHIVLSNHKDFKAVATDSHRMSQRLITLDNTSADFMVVLPSKSLREFSAVFTDDIETVEVFFSPSQILFRSEHISFYTRLLEGNYPDTDRLLMTEFETEVVFNTQSLRHAMERAFLISNATQNGTVKLEITQNHISAHVNSPEVGKVNEDLDIVSQSGSDLTISFNPTYLIESLKAIKSETVKIHFLSPVRPFTLTPGDEEESFIQLITPVRT

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transferase
source organism	Streptococcus pyogenes
publication title	Crystal structure of a DNA polymerase sliding clamp from a Gram-positive bacterium. pubmed doi rcsb
molecule keywords	DNA polymerase III beta subunit
total genus	92
structure length	372
sequence length	377
chains with identical sequence	B
ec nomenclature	ec 2.7.7.-:
pdb deposition date	2005-08-30

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00712	DNA_pol3_beta	DNA polymerase III beta subunit, N-terminal domain
A	PF02767	DNA_pol3_beta_2	DNA polymerase III beta subunit, central domain
A	PF02768	DNA_pol3_beta_3	DNA polymerase III beta subunit, C-terminal domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.10.150.10	Alpha Beta	Roll	DNA Polymerase III; Chain A, domain 2	DNA Polymerase III, subunit A, domain 2	2avtA01
3.70.10.10	Alpha Beta	Box	Proliferating Cell Nuclear Antigen	Proliferating Cell Nuclear Antigen	2avtA02

3HSLX 4TSZA 5FRQA 3QSBB 3V61B 2HIIB 4TRTA 1UL1A 1UD9A 5IY4A 5E0VA 2ZVVA 2HIKB 1B77A 4L6PA 1W60A 2HIIC 3T0PA 1RWZA 3P83A 1JQLA 1IZ5A 2IJXA 2ZVKA 2HIKC 1T6LA 4N94A 3U5ZF 4K74A 4K3QA 1ISQA 4K3MA 4YHRA 2IO4B 4OVGA 5HACA 1OK7A 1PLRA 4L60A 2NTIB 5DA7A 2ZVWA 5FVEA 4TR7A 5AH2A 2NTIC 4CS5A 3LX2A 4N96A 3BEPA 3G65B 3D1EA 4OVFA 2IX2B 2OD8A 4K3PA 3Q4JA 3GPMA 3G65C 3U60F 5AGVA 4N9AA 4PNUA 3VKXA 3Q4LA 2IX2C 3A1JA 1B8HA 4D2GA 4MJPA 1U7BA 3PWEA 3GGRA 3AIZC 4TR6A 5AGUA 1CZDA 2ZVMA 5IXAA 3GPNA 3V60B 1VYJA 2AVTA 3L0WA 5CFKA 4K3SA 3LX1A 5A6DA 4K3RA 3V62B 3I2MX 1PLQA 3F1VA 5AH4A 1IZ4A 4ZTDA 3HI8A 1UNNA 2IZOB 3IFVA 3A1JB 2HIIA 3AIXA 2IZOC 2HIKA 3FDSC 2POLA 2AWAA 3D1GA 3P16A 3A1JC 1RXZA 5E0UA 1VYMA 3L10A 1DMLA 2XURA 1GE8A 3PGEB 2IO4A 4N97A 1SXJF 4N98A 4OVHA 3FDSD 1VPKA 2Z0LA 2NTIA 5E0TA 4N95A 4RKIA 3AIXB 1U76A 3F1WA 3A2FB 3QSBA 4N99A 4PNWA 3G65A 5JNED 5DAIA 4MJQA 3P91A 2IX2A 3GGRB 3K4XA 3U61F 3AIZA 4HK1A 3WGWA 1RXMA 4TR8A 1JQJA 5IWDA 1MMIA 2ZVLA 3GGRC 3D1FA 4S3IA 1AXCA 4K3OA 3P87A 5AUJA 4K3LA 4K3KA 1YYPA 5H0TA 4PNVA 4MJRA 3L0XA 3TBLA 4RJFA 3Q4KA 5B7OA 3RB9A
chains in the Genus database with same CATH superfamily

3HSLX 4TSZA 5FRQA 3QSBB 3V61B 2HIIB 4TRTA 1UL1A 1UD9A 5IY4A 5E0VA 2ZVVA 2HIKB 1B77A 4L6PA 1W60A 2HIIC 3T0PA 1RWZA 3P83A 1JQLA 1IZ5A 2IJXA 2ZVKA 2HIKC 1T6LA 3L10B 4N94A 4K74A 3U5ZF 4K3QA 1ISQA 4K3MA 4YHRA 2IO4B 4OVGA 5HACA 1OK7A 1PLRA 4L60A 2NTIB 5DA7A 2ZVWA 5FVEA 4TR7A 5AH2A 2NTIC 4CS5A 3LX2A 4N96A 3BEPA 3G65B 3D1EA 4OVFA 2IX2B 2OD8A 4K3PA 3Q4JA 3GPMA 3G65C 3U60F 5AGVA 4N9AA 4PNUA 3VKXA 3Q4LA 2IX2C 3A1JA 1B8HA 4D2GA 4MJPA 1U7BA 3PWEA 3GGRA 3AIZC 4TR6A 5AGUA 1CZDA 2ZVMA 5IXAA 3GPNA 3V60B 1VYJA 2AVTA 3L0WA 3L0XB 5CFKA 4K3SA 3LX1A 3PGEA 5A6DA 4K3RA 3V62B 3I2MX 1PLQA 3F1VA 5AH4A 1IZ4A 4ZTDA 3HI8A 1UNNA 2IZOB 3IFVA 3A1JB 2HIIA 3AIXA 2IZOC 2HIKA 3FDSC 2POLA 2AWAA 3D1GA 3P16A 3A1JC 1RXZA 5E0UA 1VYMA 3L0WB 3L10A 1DMLA 2XURA 1GE8A 3PGEB 2IO4A 4N97A 1SXJF 4N98A 4OVHA 3FDSD 1VPKA 2Z0LA 2NTIA 5E0TA 4N95A 4RKIA 3AIXB 1U76A 3F1WA 3A2FB 3QSBA 4N99A 4PNWA 3G65A 5JNED 5DAIA 4MJQA 3P91A 2IX2A 3GGRB 3K4XA 3U61F 3AIZA 4HK1A 3WGWA 1RXMA 4TR8A 1JQJA 5IWDA 1MMIA 2ZVLA 3GGRC 3D1FA 4S3IA 1AXCA 4K3OA 3P87A 5AUJA 4K3LA 4K3KA 1YYPA 5H0TA 4PNVA 4MJRA 3L0XA 3TBLA 4RJFA 3Q4KA 5B7OA 3RB9A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 3HSL X;  4TSZ A;  5FRQ A;  3QSB B;  3V61 B;  2HII B;  4TRT A;  1UL1 A;  1UD9 A;  5IY4 A;  5E0V A;  2ZVV A;  2HIK B;  1B77 A;  4L6P A;  1W60 A;  2HII C;  3T0P A;  1RWZ A;  3P83 A;  1JQL A;  1IZ5 A;  2IJX A;  2ZVK A;  2HIK C;  1T6L A;  4N94 A;  3U5Z F;  4K74 A;  4K3Q A;  1ISQ A;  4K3M A;  4YHR A;  2IO4 B;  4OVG A;  5HAC A;  1OK7 A;  1PLR A;  4L60 A;  2NTI B;  5DA7 A;  2ZVW A;  5FVE A;  4TR7 A;  5AH2 A;  2NTI C;  4CS5 A;  3LX2 A;  4N96 A;  3BEP A;  3G65 B;  3D1E A;  4OVF A;  2IX2 B;  2OD8 A;  4K3P A;  3Q4J A;  3GPM A;  3G65 C;  3U60 F;  5AGV A;  4N9A A;  4PNU A;  3VKX A;  3Q4L A;  2IX2 C;  3A1J A;  1B8H A;  4D2G A;  4MJP A;  1U7B A;  3PWE A;  3GGR A;  3AIZ C;  4TR6 A;  5AGU A;  1CZD A;  2ZVM A;  5IXA A;  3GPN A;  3V60 B;  1VYJ A;  2AVT A;  3L0W A;  5CFK A;  4K3S A;  3LX1 A;  5A6D A;  4K3R A;  3V62 B;  3I2M X;  1PLQ A;  3F1V A;  5AH4 A;  1IZ4 A;  4ZTD A;  3HI8 A;  1UNN A;  2IZO B;  3IFV A;  3A1J B;  2HII A;  3AIX A;  2IZO C;  2HIK A;  3FDS C;  2POL A;  2AWA A;  3D1G A;  3P16 A;  3A1J C;  1RXZ A;  5E0U A;  1VYM A;  3L10 A;  1DML A;  2XUR A;  1GE8 A;  3PGE B;  2IO4 A;  4N97 A;  1SXJ F;  4N98 A;  4OVH A;  3FDS D;  1VPK A;  2Z0L A;  2NTI A;  5E0T A;  4N95 A;  4RKI A;  3AIX B;  1U76 A;  3F1W A;  3A2F B;  3QSB A;  4N99 A;  4PNW A;  3G65 A;  5JNE D;  5DAI A;  4MJQ A;  3P91 A;  2IX2 A;  3GGR B;  3K4X A;  3U61 F;  3AIZ A;  4HK1 A;  3WGW A;  1RXM A;  4TR8 A;  1JQJ A;  5IWD A;  1MMI A;  2ZVL A;  3GGR C;  3D1F A;  4S3I A;  1AXC A;  4K3O A;  3P87 A;  5AUJ A;  4K3L A;  4K3K A;  1YYP A;  5H0T A;  4PNV A;  4MJR A;  3L0X A;  3TBL A;  4RJF A;  3Q4K A;  5B7O A;  3RB9 A; 
#chains in the Genus database with same CATH topology
 3HSL X;  4TSZ A;  5FRQ A;  3QSB B;  3V61 B;  2HII B;  4TRT A;  1UL1 A;  1UD9 A;  5IY4 A;  5E0V A;  2ZVV A;  2HIK B;  1B77 A;  4L6P A;  1W60 A;  2HII C;  3T0P A;  1RWZ A;  3P83 A;  1JQL A;  1IZ5 A;  2IJX A;  2ZVK A;  2HIK C;  1T6L A;  3L10 B;  4N94 A;  4K74 A;  3U5Z F;  4K3Q A;  1ISQ A;  4K3M A;  4YHR A;  2IO4 B;  4OVG A;  5HAC A;  1OK7 A;  1PLR A;  4L60 A;  2NTI B;  5DA7 A;  2ZVW A;  5FVE A;  4TR7 A;  5AH2 A;  2NTI C;  4CS5 A;  3LX2 A;  4N96 A;  3BEP A;  3G65 B;  3D1E A;  4OVF A;  2IX2 B;  2OD8 A;  4K3P A;  3Q4J A;  3GPM A;  3G65 C;  3U60 F;  5AGV A;  4N9A A;  4PNU A;  3VKX A;  3Q4L A;  2IX2 C;  3A1J A;  1B8H A;  4D2G A;  4MJP A;  1U7B A;  3PWE A;  3GGR A;  3AIZ C;  4TR6 A;  5AGU A;  1CZD A;  2ZVM A;  5IXA A;  3GPN A;  3V60 B;  1VYJ A;  2AVT A;  3L0W A;  3L0X B;  5CFK A;  4K3S A;  3LX1 A;  3PGE A;  5A6D A;  4K3R A;  3V62 B;  3I2M X;  1PLQ A;  3F1V A;  5AH4 A;  1IZ4 A;  4ZTD A;  3HI8 A;  1UNN A;  2IZO B;  3IFV A;  3A1J B;  2HII A;  3AIX A;  2IZO C;  2HIK A;  3FDS C;  2POL A;  2AWA A;  3D1G A;  3P16 A;  3A1J C;  1RXZ A;  5E0U A;  1VYM A;  3L0W B;  3L10 A;  1DML A;  2XUR A;  1GE8 A;  3PGE B;  2IO4 A;  4N97 A;  1SXJ F;  4N98 A;  4OVH A;  3FDS D;  1VPK A;  2Z0L A;  2NTI A;  5E0T A;  4N95 A;  4RKI A;  3AIX B;  1U76 A;  3F1W A;  3A2F B;  3QSB A;  4N99 A;  4PNW A;  3G65 A;  5JNE D;  5DAI A;  4MJQ A;  3P91 A;  2IX2 A;  3GGR B;  3K4X A;  3U61 F;  3AIZ A;  4HK1 A;  3WGW A;  1RXM A;  4TR8 A;  1JQJ A;  5IWD A;  1MMI A;  2ZVL A;  3GGR C;  3D1F A;  4S3I A;  1AXC A;  4K3O A;  3P87 A;  5AUJ A;  4K3L A;  4K3K A;  1YYP A;  5H0T A;  4PNV A;  4MJR A;  3L0X A;  3TBL A;  4RJF A;  3Q4K A;  5B7O A;  3RB9 A; 
#chains in the Genus database with same CATH homology
 3HSL X;  4TSZ A;  5FRQ A;  3QSB B;  3V61 B;  2HII B;  4TRT A;  1UL1 A;  1UD9 A;  5IY4 A;  5E0V A;  2ZVV A;  2HIK B;  1B77 A;  4L6P A;  1W60 A;  2HII C;  3T0P A;  1RWZ A;  3P83 A;  1JQL A;  1IZ5 A;  2IJX A;  2ZVK A;  2HIK C;  1T6L A;  4N94 A;  3U5Z F;  4K74 A;  4K3Q A;  1ISQ A;  4K3M A;  4YHR A;  2IO4 B;  4OVG A;  5HAC A;  1OK7 A;  1PLR A;  4L60 A;  2NTI B;  5DA7 A;  2ZVW A;  5FVE A;  4TR7 A;  5AH2 A;  2NTI C;  4CS5 A;  3LX2 A;  4N96 A;  3BEP A;  3G65 B;  3D1E A;  4OVF A;  2IX2 B;  2OD8 A;  4K3P A;  3Q4J A;  3GPM A;  3G65 C;  3U60 F;  5AGV A;  4N9A A;  4PNU A;  3VKX A;  3Q4L A;  2IX2 C;  3A1J A;  1B8H A;  4D2G A;  4MJP A;  1U7B A;  3PWE A;  3GGR A;  3AIZ C;  4TR6 A;  5AGU A;  1CZD A;  2ZVM A;  5IXA A;  3GPN A;  3V60 B;  1VYJ A;  2AVT A;  3L0W A;  5CFK A;  4K3S A;  3LX1 A;  5A6D A;  4K3R A;  3V62 B;  3I2M X;  1PLQ A;  3F1V A;  5AH4 A;  1IZ4 A;  4ZTD A;  3HI8 A;  1UNN A;  2IZO B;  3IFV A;  3A1J B;  2HII A;  3AIX A;  2IZO C;  2HIK A;  3FDS C;  2POL A;  2AWA A;  3D1G A;  3P16 A;  3A1J C;  1RXZ A;  5E0U A;  1VYM A;  3L10 A;  1DML A;  2XUR A;  1GE8 A;  3PGE B;  2IO4 A;  4N97 A;  1SXJ F;  4N98 A;  4OVH A;  3FDS D;  1VPK A;  2Z0L A;  2NTI A;  5E0T A;  4N95 A;  4RKI A;  3AIX B;  1U76 A;  3F1W A;  3A2F B;  3QSB A;  4N99 A;  4PNW A;  3G65 A;  5JNE D;  5DAI A;  4MJQ A;  3P91 A;  2IX2 A;  3GGR B;  3K4X A;  3U61 F;  3AIZ A;  4HK1 A;  3WGW A;  1RXM A;  4TR8 A;  1JQJ A;  5IWD A;  1MMI A;  2ZVL A;  3GGR C;  3D1F A;  4S3I A;  1AXC A;  4K3O A;  3P87 A;  5AUJ A;  4K3L A;  4K3K A;  1YYP A;  5H0T A;  4PNV A;  4MJR A;  3L0X A;  3TBL A;  4RJF A;  3Q4K A;  5B7O A;  3RB9 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

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2AVTA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations