2AVTA

Crystal structure of the beta subunit from dna polymerase of streptococcus pyogenes
Total Genus 92
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
92
sequence length
377
structure length
372
Chain Sequence
MIQFSINRTLFIHALNTTKRAISTKNAIPILSSIKIEVTSTGVTLTGSNGQISIENTIPVGLLITSPGAILLEASFFINIISSLPDISINVKEIEQHQVVLTSGKSEITLKGKDVDQYPRLQEVSTENPLILKTKLLKSIIAETAFAASLQESRPILTGVHIVLSNHKDFKAVATDSHRMSQRLITLDNTSADFMVVLPSKSLREFSAVFTDDIETVEVFFSPSQILFRSEHISFYTRLLEGNYPDTDRLLMTEFETEVVFNTQSLRHAMERAFLISNATQNGTVKLEITQNHISAHVNSPEVGKVNEDLDIVSQSGSDLTISFNPTYLIESLKAIKSETVKIHFLSPVRPFTLTPGDEEESFIQLITPVRT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of a DNA polymerase sliding clamp from a Gram-positive bacterium.
pubmed doi rcsb
molecule tags Transferase
source organism Streptococcus pyogenes
molecule keywords DNA polymerase III beta subunit
total genus 92
structure length 372
sequence length 377
chains with identical sequence B
ec nomenclature ec 2.7.7.-:
pdb deposition date 2005-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00712 DNA_pol3_beta DNA polymerase III beta subunit, N-terminal domain
A PF02767 DNA_pol3_beta_2 DNA polymerase III beta subunit, central domain
A PF02768 DNA_pol3_beta_3 DNA polymerase III beta subunit, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 2avtA01
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 2avtA02
2NTIB 2HIIB 3D1EA 1B8HA 3LX2A 4N99A 3BEPA 1SXJF 2AVTA 4K3LA 1RXMA 3A1JB 2HIIA 4OVGA 4K3QA 4TR8A 1AXCA 5H0TA 3GGRB 3L0WA 3L10A 1PLQA 2IZOB 4L60A 5B7OA 3Q4JA 3Q4KA 4YHRA 1UL1A 3I2MX 3GGRA 2IJXA 4K3SA 1T6LA 1VPKA 1ISQA 1RXZA 5AGVA 4MJQA 2ZVVA 3WGWA 4OVHA 3G65C 2ZVLA 5AGUA 4N97A 1W60A 4N95A 5JNED 3LX1A 4L6PA 1RWZA 3HSLX 2NTIA 3V60B 4S3IA 1U76A 2HIKC 5E0VA 3F1WA 1DMLA 4ZTDA 5FVEA 3AIZC 3A1JA 3P87A 2IX2C 3VKXA 4N94A 1YYPA 3U61F 4MJRA 2AWAA 5AH4A 1VYJA 3FDSD 4K3PA 4K3KA 3Q4LA 1MMIA 1UD9A 1UNNA 4N9AA 4OVFA 3RB9A 2OD8A 3U60F 3GPNA 4K3RA 4RKIA 4PNUA 3D1FA 1JQJA 4MJPA 5E0TA 5AUJA 5CFKA 5DAIA 4PNWA 5IWDA 4K3OA 1PLRA 1JQLA 2ZVWA 3G65B 3TBLA 3V61B 3IFVA 4N98A 4PNVA 1VYMA 4N96A 4RJFA 3QSBB 3G65A 5HACA 3T0PA 2HIKB 2NTIC 1U7BA 2HIIC 1B77A 3AIXB 4TRTA 2IX2B 3PGEB 3QSBA 2HIKA 3U5ZF 5IXAA 3L0XA 2ZVKA 5IY4A 3A1JC 1CZDA 2XURA 3AIZA 3AIXA 1GE8A 2IX2A 5AH2A 3GGRC 5FRQA 3V62B 3D1GA 3PWEA 4K3MA 2IZOC 2IO4B 4TR7A 2Z0LA 3HI8A 2POLA 2ZVMA 4HK1A 1IZ4A 5E0UA 5DA7A 1IZ5A 4D2GA 2IO4A 3P16A 4TSZA 3A2FB 4CS5A 3K4XA 4K74A 3FDSC 3F1VA 1OK7A 3P83A 4TR6A 5A6DA 3P91A 3GPMA
chains in the Genus database with same CATH superfamily
2NTIB 2HIIB 3D1EA 1B8HA 3LX2A 4N99A 3BEPA 1SXJF 3L0WB 3L10B 2AVTA 3PGEA 4K3LA 1RXMA 3A1JB 2HIIA 4OVGA 4K3QA 4TR8A 1AXCA 5H0TA 3GGRB 3L0WA 3L10A 1PLQA 2IZOB 4L60A 5B7OA 3Q4JA 3Q4KA 4YHRA 1UL1A 3I2MX 3GGRA 2IJXA 4K3SA 1T6LA 1VPKA 1ISQA 1RXZA 5AGVA 4MJQA 2ZVVA 3WGWA 4OVHA 3G65C 2ZVLA 5AGUA 4N97A 1W60A 4N95A 5JNED 3LX1A 4L6PA 1RWZA 3HSLX 2NTIA 3V60B 4S3IA 1U76A 2HIKC 5E0VA 3F1WA 1DMLA 4ZTDA 5FVEA 3AIZC 3A1JA 3P87A 2IX2C 3VKXA 4N94A 1YYPA 3U61F 4MJRA 2AWAA 5AH4A 1VYJA 3FDSD 4K3PA 4K3KA 3Q4LA 1MMIA 1UD9A 1UNNA 4N9AA 4OVFA 3RB9A 2OD8A 3U60F 3GPNA 4K3RA 4RKIA 4PNUA 3D1FA 1JQJA 4MJPA 5E0TA 5AUJA 5CFKA 5DAIA 4PNWA 5IWDA 4K3OA 1PLRA 1JQLA 2ZVWA 3G65B 3TBLA 3V61B 3IFVA 4N98A 4PNVA 1VYMA 4N96A 4RJFA 3QSBB 3G65A 5HACA 3T0PA 2HIKB 3L0XB 2NTIC 1U7BA 2HIIC 1B77A 3AIXB 4TRTA 2IX2B 3PGEB 3QSBA 2HIKA 3U5ZF 5IXAA 3L0XA 2ZVKA 5IY4A 3A1JC 1CZDA 2XURA 3AIZA 3AIXA 1GE8A 2IX2A 5AH2A 3GGRC 5FRQA 3V62B 3D1GA 3PWEA 4K3MA 2IZOC 2IO4B 4TR7A 2Z0LA 3HI8A 2POLA 2ZVMA 4HK1A 1IZ4A 5E0UA 5DA7A 1IZ5A 4D2GA 2IO4A 3P16A 4TSZA 3A2FB 4CS5A 3K4XA 4K74A 3FDSC 3F1VA 1OK7A 3P83A 4TR6A 5A6DA 3P91A 3GPMA
chains in the Genus database with same CATH topology
2NTIB 2HIIB 3D1EA 1B8HA 3LX2A 4N99A 3BEPA 1SXJF 2AVTA 4K3LA 1RXMA 3A1JB 2HIIA 4OVGA 4K3QA 4TR8A 1AXCA 5H0TA 3GGRB 3L0WA 3L10A 1PLQA 2IZOB 4L60A 5B7OA 3Q4JA 3Q4KA 4YHRA 1UL1A 3I2MX 3GGRA 2IJXA 4K3SA 1T6LA 1VPKA 1ISQA 1RXZA 5AGVA 4MJQA 2ZVVA 3WGWA 4OVHA 3G65C 2ZVLA 5AGUA 4N97A 1W60A 4N95A 5JNED 3LX1A 4L6PA 1RWZA 3HSLX 2NTIA 3V60B 4S3IA 1U76A 2HIKC 5E0VA 3F1WA 1DMLA 4ZTDA 5FVEA 3AIZC 3A1JA 3P87A 2IX2C 3VKXA 4N94A 1YYPA 3U61F 4MJRA 2AWAA 5AH4A 1VYJA 3FDSD 4K3PA 4K3KA 3Q4LA 1MMIA 1UD9A 1UNNA 4N9AA 4OVFA 3RB9A 2OD8A 3U60F 3GPNA 4K3RA 4RKIA 4PNUA 3D1FA 1JQJA 4MJPA 5E0TA 5AUJA 5CFKA 5DAIA 4PNWA 5IWDA 4K3OA 1PLRA 1JQLA 2ZVWA 3G65B 3TBLA 3V61B 3IFVA 4N98A 4PNVA 1VYMA 4N96A 4RJFA 3QSBB 3G65A 5HACA 3T0PA 2HIKB 2NTIC 1U7BA 2HIIC 1B77A 3AIXB 4TRTA 2IX2B 3PGEB 3QSBA 2HIKA 3U5ZF 5IXAA 3L0XA 2ZVKA 5IY4A 3A1JC 1CZDA 2XURA 3AIZA 3AIXA 1GE8A 2IX2A 5AH2A 3GGRC 5FRQA 3V62B 3D1GA 3PWEA 4K3MA 2IZOC 2IO4B 4TR7A 2Z0LA 3HI8A 2POLA 2ZVMA 4HK1A 1IZ4A 5E0UA 5DA7A 1IZ5A 4D2GA 2IO4A 3P16A 4TSZA 3A2FB 4CS5A 3K4XA 4K74A 3FDSC 3F1VA 1OK7A 3P83A 4TR6A 5A6DA 3P91A 3GPMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NTI B;  2HII B;  3D1E A;  1B8H A;  3LX2 A;  4N99 A;  3BEP A;  1SXJ F;  2AVT A;  4K3L A;  1RXM A;  3A1J B;  2HII A;  4OVG A;  4K3Q A;  4TR8 A;  1AXC A;  5H0T A;  3GGR B;  3L0W A;  3L10 A;  1PLQ A;  2IZO B;  4L60 A;  5B7O A;  3Q4J A;  3Q4K A;  4YHR A;  1UL1 A;  3I2M X;  3GGR A;  2IJX A;  4K3S A;  1T6L A;  1VPK A;  1ISQ A;  1RXZ A;  5AGV A;  4MJQ A;  2ZVV A;  3WGW A;  4OVH A;  3G65 C;  2ZVL A;  5AGU A;  4N97 A;  1W60 A;  4N95 A;  5JNE D;  3LX1 A;  4L6P A;  1RWZ A;  3HSL X;  2NTI A;  3V60 B;  4S3I A;  1U76 A;  2HIK C;  5E0V A;  3F1W A;  1DML A;  4ZTD A;  5FVE A;  3AIZ C;  3A1J A;  3P87 A;  2IX2 C;  3VKX A;  4N94 A;  1YYP A;  3U61 F;  4MJR A;  2AWA A;  5AH4 A;  1VYJ A;  3FDS D;  4K3P A;  4K3K A;  3Q4L A;  1MMI A;  1UD9 A;  1UNN A;  4N9A A;  4OVF A;  3RB9 A;  2OD8 A;  3U60 F;  3GPN A;  4K3R A;  4RKI A;  4PNU A;  3D1F A;  1JQJ A;  4MJP A;  5E0T A;  5AUJ A;  5CFK A;  5DAI A;  4PNW A;  5IWD A;  4K3O A;  1PLR A;  1JQL A;  2ZVW A;  3G65 B;  3TBL A;  3V61 B;  3IFV A;  4N98 A;  4PNV A;  1VYM A;  4N96 A;  4RJF A;  3QSB B;  3G65 A;  5HAC A;  3T0P A;  2HIK B;  2NTI C;  1U7B A;  2HII C;  1B77 A;  3AIX B;  4TRT A;  2IX2 B;  3PGE B;  3QSB A;  2HIK A;  3U5Z F;  5IXA A;  3L0X A;  2ZVK A;  5IY4 A;  3A1J C;  1CZD A;  2XUR A;  3AIZ A;  3AIX A;  1GE8 A;  2IX2 A;  5AH2 A;  3GGR C;  5FRQ A;  3V62 B;  3D1G A;  3PWE A;  4K3M A;  2IZO C;  2IO4 B;  4TR7 A;  2Z0L A;  3HI8 A;  2POL A;  2ZVM A;  4HK1 A;  1IZ4 A;  5E0U A;  5DA7 A;  1IZ5 A;  4D2G A;  2IO4 A;  3P16 A;  4TSZ A;  3A2F B;  4CS5 A;  3K4X A;  4K74 A;  3FDS C;  3F1V A;  1OK7 A;  3P83 A;  4TR6 A;  5A6D A;  3P91 A;  3GPM A; 
#chains in the Genus database with same CATH topology
 2NTI B;  2HII B;  3D1E A;  1B8H A;  3LX2 A;  4N99 A;  3BEP A;  1SXJ F;  3L0W B;  3L10 B;  2AVT A;  3PGE A;  4K3L A;  1RXM A;  3A1J B;  2HII A;  4OVG A;  4K3Q A;  4TR8 A;  1AXC A;  5H0T A;  3GGR B;  3L0W A;  3L10 A;  1PLQ A;  2IZO B;  4L60 A;  5B7O A;  3Q4J A;  3Q4K A;  4YHR A;  1UL1 A;  3I2M X;  3GGR A;  2IJX A;  4K3S A;  1T6L A;  1VPK A;  1ISQ A;  1RXZ A;  5AGV A;  4MJQ A;  2ZVV A;  3WGW A;  4OVH A;  3G65 C;  2ZVL A;  5AGU A;  4N97 A;  1W60 A;  4N95 A;  5JNE D;  3LX1 A;  4L6P A;  1RWZ A;  3HSL X;  2NTI A;  3V60 B;  4S3I A;  1U76 A;  2HIK C;  5E0V A;  3F1W A;  1DML A;  4ZTD A;  5FVE A;  3AIZ C;  3A1J A;  3P87 A;  2IX2 C;  3VKX A;  4N94 A;  1YYP A;  3U61 F;  4MJR A;  2AWA A;  5AH4 A;  1VYJ A;  3FDS D;  4K3P A;  4K3K A;  3Q4L A;  1MMI A;  1UD9 A;  1UNN A;  4N9A A;  4OVF A;  3RB9 A;  2OD8 A;  3U60 F;  3GPN A;  4K3R A;  4RKI A;  4PNU A;  3D1F A;  1JQJ A;  4MJP A;  5E0T A;  5AUJ A;  5CFK A;  5DAI A;  4PNW A;  5IWD A;  4K3O A;  1PLR A;  1JQL A;  2ZVW A;  3G65 B;  3TBL A;  3V61 B;  3IFV A;  4N98 A;  4PNV A;  1VYM A;  4N96 A;  4RJF A;  3QSB B;  3G65 A;  5HAC A;  3T0P A;  2HIK B;  3L0X B;  2NTI C;  1U7B A;  2HII C;  1B77 A;  3AIX B;  4TRT A;  2IX2 B;  3PGE B;  3QSB A;  2HIK A;  3U5Z F;  5IXA A;  3L0X A;  2ZVK A;  5IY4 A;  3A1J C;  1CZD A;  2XUR A;  3AIZ A;  3AIX A;  1GE8 A;  2IX2 A;  5AH2 A;  3GGR C;  5FRQ A;  3V62 B;  3D1G A;  3PWE A;  4K3M A;  2IZO C;  2IO4 B;  4TR7 A;  2Z0L A;  3HI8 A;  2POL A;  2ZVM A;  4HK1 A;  1IZ4 A;  5E0U A;  5DA7 A;  1IZ5 A;  4D2G A;  2IO4 A;  3P16 A;  4TSZ A;  3A2F B;  4CS5 A;  3K4X A;  4K74 A;  3FDS C;  3F1V A;  1OK7 A;  3P83 A;  4TR6 A;  5A6D A;  3P91 A;  3GPM A; 
#chains in the Genus database with same CATH homology
 2NTI B;  2HII B;  3D1E A;  1B8H A;  3LX2 A;  4N99 A;  3BEP A;  1SXJ F;  2AVT A;  4K3L A;  1RXM A;  3A1J B;  2HII A;  4OVG A;  4K3Q A;  4TR8 A;  1AXC A;  5H0T A;  3GGR B;  3L0W A;  3L10 A;  1PLQ A;  2IZO B;  4L60 A;  5B7O A;  3Q4J A;  3Q4K A;  4YHR A;  1UL1 A;  3I2M X;  3GGR A;  2IJX A;  4K3S A;  1T6L A;  1VPK A;  1ISQ A;  1RXZ A;  5AGV A;  4MJQ A;  2ZVV A;  3WGW A;  4OVH A;  3G65 C;  2ZVL A;  5AGU A;  4N97 A;  1W60 A;  4N95 A;  5JNE D;  3LX1 A;  4L6P A;  1RWZ A;  3HSL X;  2NTI A;  3V60 B;  4S3I A;  1U76 A;  2HIK C;  5E0V A;  3F1W A;  1DML A;  4ZTD A;  5FVE A;  3AIZ C;  3A1J A;  3P87 A;  2IX2 C;  3VKX A;  4N94 A;  1YYP A;  3U61 F;  4MJR A;  2AWA A;  5AH4 A;  1VYJ A;  3FDS D;  4K3P A;  4K3K A;  3Q4L A;  1MMI A;  1UD9 A;  1UNN A;  4N9A A;  4OVF A;  3RB9 A;  2OD8 A;  3U60 F;  3GPN A;  4K3R A;  4RKI A;  4PNU A;  3D1F A;  1JQJ A;  4MJP A;  5E0T A;  5AUJ A;  5CFK A;  5DAI A;  4PNW A;  5IWD A;  4K3O A;  1PLR A;  1JQL A;  2ZVW A;  3G65 B;  3TBL A;  3V61 B;  3IFV A;  4N98 A;  4PNV A;  1VYM A;  4N96 A;  4RJF A;  3QSB B;  3G65 A;  5HAC A;  3T0P A;  2HIK B;  2NTI C;  1U7B A;  2HII C;  1B77 A;  3AIX B;  4TRT A;  2IX2 B;  3PGE B;  3QSB A;  2HIK A;  3U5Z F;  5IXA A;  3L0X A;  2ZVK A;  5IY4 A;  3A1J C;  1CZD A;  2XUR A;  3AIZ A;  3AIX A;  1GE8 A;  2IX2 A;  5AH2 A;  3GGR C;  5FRQ A;  3V62 B;  3D1G A;  3PWE A;  4K3M A;  2IZO C;  2IO4 B;  4TR7 A;  2Z0L A;  3HI8 A;  2POL A;  2ZVM A;  4HK1 A;  1IZ4 A;  5E0U A;  5DA7 A;  1IZ5 A;  4D2G A;  2IO4 A;  3P16 A;  4TSZ A;  3A2F B;  4CS5 A;  3K4X A;  4K74 A;  3FDS C;  3F1V A;  1OK7 A;  3P83 A;  4TR6 A;  5A6D A;  3P91 A;  3GPM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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