2AWAA

Crystal structure of dna polymerase iii, beta chain (ec 2.7.7.7) (np_344555.1) from streptococcus pneumoniae tigr4 at 2.50 a resolution
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
377
structure length
377
Chain Sequence
MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGITLIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQNQIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRPILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDDIETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSMERARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYLIDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of DNA polymerase III, beta chain (EC 2.7.7.7) (np_344555.1) from STREPTOCOCCUS PNEUMONIAE TIGR4 at 2.50 A resolution
rcsb
molecule tags Transferase
source organism Streptococcus pneumoniae
molecule keywords DNA polymerase III, beta chain
total genus 94
structure length 377
sequence length 377
chains with identical sequence B, C, D
ec nomenclature ec 2.7.7.7: DNA-directed DNA polymerase.
pdb deposition date 2005-08-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00712 DNA_pol3_beta DNA polymerase III beta subunit, N-terminal domain
A PF02767 DNA_pol3_beta_2 DNA polymerase III beta subunit, central domain
A PF02768 DNA_pol3_beta_3 DNA polymerase III beta subunit, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 2awaA01
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 2awaA02
5JNED 3RB9A 3LX2A 3V61B 2ZVMA 3D1EA 1DMLA 4K3LA 3FDSC 4L6PA 3Q4JA 4N9AA 2XURA 3K4XA 1VYMA 2IX2B 1GE8A 3V60B 3A1JB 4MJQA 3GGRB 5HACA 5AGVA 4OVHA 1IZ4A 5AGUA 1U7BA 2ZVLA 1ISQA 1U76A 5A6DA 2NTIA 5B7OA 3Q4KA 3P16A 4L60A 3Q4LA 3A1JA 3PGEB 1SXJF 3U5ZF 4K3QA 3LX1A 1UL1A 3GPNA 5AH4A 4HK1A 4PNWA 4N94A 1PLRA 2AWAA 3D1FA 3HSLX 2Z0LA 1RWZA 2NTIB 3FDSD 1W60A 4ZTDA 4MJPA 2IZOC 4PNUA 5FRQA 1RXZA 1PLQA 4K3MA 4TR7A 3QSBB 3TBLA 4CS5A 5CFKA 1RXMA 1CZDA 4S3IA 4N95A 4K3PA 3AIXA 3G65C 1IZ5A 5AUJA 3A2FB 3V62B 3T0PA 4D2GA 3L0XA 3BEPA 5E0VA 5FVEA 3L10A 3QSBA 2ZVWA 3L0WA 1AXCA 5AH2A 2IJXA 2HIIC 3U61F 4K3OA 1B8HA 3AIZC 3WGWA 3VKXA 3AIXB 1VPKA 4TR8A 4K3RA 2HIKC 1YYPA 5H0TA 3I2MX 3P83A 3G65A 4TSZA 5IY4A 3P91A 1MMIA 1T6LA 1B77A 1UNNA 2ZVVA 2IZOB 3PWEA 2HIKB 5DA7A 4YHRA 2IX2C 4N97A 4PNVA 3HI8A 3P87A 4K3KA 3A1JC 2HIIA 1JQLA 4OVFA 3GGRC 3D1GA 3AIZA 3F1VA 4MJRA 3G65B 2IO4A 4TRTA 4RKIA 1UD9A 2HIKA 4TR6A 4N98A 1VYJA 3F1WA 3IFVA 2ZVKA 1OK7A 4K3SA 4N99A 5DAIA 4OVGA 2HIIB 4N96A 5IWDA 2IX2A 3GPMA 4K74A 2IO4B 3U60F 1JQJA 4RJFA 5E0TA 3GGRA 2NTIC 2AVTA 5IXAA 2POLA 5E0UA 2OD8A
chains in the Genus database with same CATH superfamily
5JNED 3RB9A 3LX2A 3V61B 2ZVMA 3D1EA 1DMLA 4K3LA 3FDSC 4L6PA 3Q4JA 4N9AA 2XURA 3K4XA 1VYMA 2IX2B 1GE8A 3V60B 3A1JB 4MJQA 3GGRB 5HACA 5AGVA 4OVHA 1IZ4A 5AGUA 1U7BA 2ZVLA 1ISQA 1U76A 5A6DA 2NTIA 5B7OA 3Q4KA 3P16A 4L60A 3Q4LA 3A1JA 3PGEB 1SXJF 3U5ZF 4K3QA 3LX1A 1UL1A 3GPNA 5AH4A 4HK1A 4PNWA 4N94A 1PLRA 2AWAA 3D1FA 3HSLX 2Z0LA 1RWZA 2NTIB 3FDSD 1W60A 4ZTDA 4MJPA 3PGEA 2IZOC 4PNUA 5FRQA 1RXZA 1PLQA 3L10B 4K3MA 4TR7A 3QSBB 3TBLA 4CS5A 5CFKA 1RXMA 1CZDA 3L0WB 4S3IA 4N95A 4K3PA 3AIXA 3G65C 1IZ5A 5AUJA 3A2FB 3V62B 3T0PA 4D2GA 3L0XA 3BEPA 5E0VA 5FVEA 3L10A 3QSBA 2ZVWA 3L0WA 1AXCA 5AH2A 2IJXA 2HIIC 3U61F 4K3OA 1B8HA 3AIZC 3WGWA 3VKXA 3AIXB 1VPKA 4TR8A 4K3RA 2HIKC 1YYPA 5H0TA 3L0XB 3I2MX 3P83A 3G65A 4TSZA 5IY4A 3P91A 1MMIA 1T6LA 1B77A 1UNNA 2ZVVA 2IZOB 3PWEA 2HIKB 5DA7A 4YHRA 2IX2C 4N97A 4PNVA 3HI8A 3P87A 4K3KA 3A1JC 2HIIA 1JQLA 4OVFA 3GGRC 3D1GA 3AIZA 3F1VA 4MJRA 3G65B 2IO4A 4TRTA 4RKIA 1UD9A 2HIKA 4TR6A 4N98A 1VYJA 3F1WA 3IFVA 2ZVKA 1OK7A 4K3SA 4N99A 5DAIA 4OVGA 2HIIB 4N96A 5IWDA 2IX2A 3GPMA 4K74A 2IO4B 3U60F 1JQJA 4RJFA 5E0TA 3GGRA 2NTIC 2AVTA 5IXAA 2POLA 5E0UA 2OD8A
chains in the Genus database with same CATH topology
5JNED 3RB9A 3LX2A 3V61B 2ZVMA 3D1EA 1DMLA 4K3LA 3FDSC 4L6PA 3Q4JA 4N9AA 2XURA 3K4XA 1VYMA 2IX2B 1GE8A 3V60B 3A1JB 4MJQA 3GGRB 5HACA 5AGVA 4OVHA 1IZ4A 5AGUA 1U7BA 2ZVLA 1ISQA 1U76A 5A6DA 2NTIA 5B7OA 3Q4KA 3P16A 4L60A 3Q4LA 3A1JA 3PGEB 1SXJF 3U5ZF 4K3QA 3LX1A 1UL1A 3GPNA 5AH4A 4HK1A 4PNWA 4N94A 1PLRA 2AWAA 3D1FA 3HSLX 2Z0LA 1RWZA 2NTIB 3FDSD 1W60A 4ZTDA 4MJPA 2IZOC 4PNUA 5FRQA 1RXZA 1PLQA 4K3MA 4TR7A 3QSBB 3TBLA 4CS5A 5CFKA 1RXMA 1CZDA 4S3IA 4N95A 4K3PA 3AIXA 3G65C 1IZ5A 5AUJA 3A2FB 3V62B 3T0PA 4D2GA 3L0XA 3BEPA 5E0VA 5FVEA 3L10A 3QSBA 2ZVWA 3L0WA 1AXCA 5AH2A 2IJXA 2HIIC 3U61F 4K3OA 1B8HA 3AIZC 3WGWA 3VKXA 3AIXB 1VPKA 4TR8A 4K3RA 2HIKC 1YYPA 5H0TA 3I2MX 3P83A 3G65A 4TSZA 5IY4A 3P91A 1MMIA 1T6LA 1B77A 1UNNA 2ZVVA 2IZOB 3PWEA 2HIKB 5DA7A 4YHRA 2IX2C 4N97A 4PNVA 3HI8A 3P87A 4K3KA 3A1JC 2HIIA 1JQLA 4OVFA 3GGRC 3D1GA 3AIZA 3F1VA 4MJRA 3G65B 2IO4A 4TRTA 4RKIA 1UD9A 2HIKA 4TR6A 4N98A 1VYJA 3F1WA 3IFVA 2ZVKA 1OK7A 4K3SA 4N99A 5DAIA 4OVGA 2HIIB 4N96A 5IWDA 2IX2A 3GPMA 4K74A 2IO4B 3U60F 1JQJA 4RJFA 5E0TA 3GGRA 2NTIC 2AVTA 5IXAA 2POLA 5E0UA 2OD8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5JNE D;  3RB9 A;  3LX2 A;  3V61 B;  2ZVM A;  3D1E A;  1DML A;  4K3L A;  3FDS C;  4L6P A;  3Q4J A;  4N9A A;  2XUR A;  3K4X A;  1VYM A;  2IX2 B;  1GE8 A;  3V60 B;  3A1J B;  4MJQ A;  3GGR B;  5HAC A;  5AGV A;  4OVH A;  1IZ4 A;  5AGU A;  1U7B A;  2ZVL A;  1ISQ A;  1U76 A;  5A6D A;  2NTI A;  5B7O A;  3Q4K A;  3P16 A;  4L60 A;  3Q4L A;  3A1J A;  3PGE B;  1SXJ F;  3U5Z F;  4K3Q A;  3LX1 A;  1UL1 A;  3GPN A;  5AH4 A;  4HK1 A;  4PNW A;  4N94 A;  1PLR A;  2AWA A;  3D1F A;  3HSL X;  2Z0L A;  1RWZ A;  2NTI B;  3FDS D;  1W60 A;  4ZTD A;  4MJP A;  2IZO C;  4PNU A;  5FRQ A;  1RXZ A;  1PLQ A;  4K3M A;  4TR7 A;  3QSB B;  3TBL A;  4CS5 A;  5CFK A;  1RXM A;  1CZD A;  4S3I A;  4N95 A;  4K3P A;  3AIX A;  3G65 C;  1IZ5 A;  5AUJ A;  3A2F B;  3V62 B;  3T0P A;  4D2G A;  3L0X A;  3BEP A;  5E0V A;  5FVE A;  3L10 A;  3QSB A;  2ZVW A;  3L0W A;  1AXC A;  5AH2 A;  2IJX A;  2HII C;  3U61 F;  4K3O A;  1B8H A;  3AIZ C;  3WGW A;  3VKX A;  3AIX B;  1VPK A;  4TR8 A;  4K3R A;  2HIK C;  1YYP A;  5H0T A;  3I2M X;  3P83 A;  3G65 A;  4TSZ A;  5IY4 A;  3P91 A;  1MMI A;  1T6L A;  1B77 A;  1UNN A;  2ZVV A;  2IZO B;  3PWE A;  2HIK B;  5DA7 A;  4YHR A;  2IX2 C;  4N97 A;  4PNV A;  3HI8 A;  3P87 A;  4K3K A;  3A1J C;  2HII A;  1JQL A;  4OVF A;  3GGR C;  3D1G A;  3AIZ A;  3F1V A;  4MJR A;  3G65 B;  2IO4 A;  4TRT A;  4RKI A;  1UD9 A;  2HIK A;  4TR6 A;  4N98 A;  1VYJ A;  3F1W A;  3IFV A;  2ZVK A;  1OK7 A;  4K3S A;  4N99 A;  5DAI A;  4OVG A;  2HII B;  4N96 A;  5IWD A;  2IX2 A;  3GPM A;  4K74 A;  2IO4 B;  3U60 F;  1JQJ A;  4RJF A;  5E0T A;  3GGR A;  2NTI C;  2AVT A;  5IXA A;  2POL A;  5E0U A;  2OD8 A; 
#chains in the Genus database with same CATH topology
 5JNE D;  3RB9 A;  3LX2 A;  3V61 B;  2ZVM A;  3D1E A;  1DML A;  4K3L A;  3FDS C;  4L6P A;  3Q4J A;  4N9A A;  2XUR A;  3K4X A;  1VYM A;  2IX2 B;  1GE8 A;  3V60 B;  3A1J B;  4MJQ A;  3GGR B;  5HAC A;  5AGV A;  4OVH A;  1IZ4 A;  5AGU A;  1U7B A;  2ZVL A;  1ISQ A;  1U76 A;  5A6D A;  2NTI A;  5B7O A;  3Q4K A;  3P16 A;  4L60 A;  3Q4L A;  3A1J A;  3PGE B;  1SXJ F;  3U5Z F;  4K3Q A;  3LX1 A;  1UL1 A;  3GPN A;  5AH4 A;  4HK1 A;  4PNW A;  4N94 A;  1PLR A;  2AWA A;  3D1F A;  3HSL X;  2Z0L A;  1RWZ A;  2NTI B;  3FDS D;  1W60 A;  4ZTD A;  4MJP A;  3PGE A;  2IZO C;  4PNU A;  5FRQ A;  1RXZ A;  1PLQ A;  3L10 B;  4K3M A;  4TR7 A;  3QSB B;  3TBL A;  4CS5 A;  5CFK A;  1RXM A;  1CZD A;  3L0W B;  4S3I A;  4N95 A;  4K3P A;  3AIX A;  3G65 C;  1IZ5 A;  5AUJ A;  3A2F B;  3V62 B;  3T0P A;  4D2G A;  3L0X A;  3BEP A;  5E0V A;  5FVE A;  3L10 A;  3QSB A;  2ZVW A;  3L0W A;  1AXC A;  5AH2 A;  2IJX A;  2HII C;  3U61 F;  4K3O A;  1B8H A;  3AIZ C;  3WGW A;  3VKX A;  3AIX B;  1VPK A;  4TR8 A;  4K3R A;  2HIK C;  1YYP A;  5H0T A;  3L0X B;  3I2M X;  3P83 A;  3G65 A;  4TSZ A;  5IY4 A;  3P91 A;  1MMI A;  1T6L A;  1B77 A;  1UNN A;  2ZVV A;  2IZO B;  3PWE A;  2HIK B;  5DA7 A;  4YHR A;  2IX2 C;  4N97 A;  4PNV A;  3HI8 A;  3P87 A;  4K3K A;  3A1J C;  2HII A;  1JQL A;  4OVF A;  3GGR C;  3D1G A;  3AIZ A;  3F1V A;  4MJR A;  3G65 B;  2IO4 A;  4TRT A;  4RKI A;  1UD9 A;  2HIK A;  4TR6 A;  4N98 A;  1VYJ A;  3F1W A;  3IFV A;  2ZVK A;  1OK7 A;  4K3S A;  4N99 A;  5DAI A;  4OVG A;  2HII B;  4N96 A;  5IWD A;  2IX2 A;  3GPM A;  4K74 A;  2IO4 B;  3U60 F;  1JQJ A;  4RJF A;  5E0T A;  3GGR A;  2NTI C;  2AVT A;  5IXA A;  2POL A;  5E0U A;  2OD8 A; 
#chains in the Genus database with same CATH homology
 5JNE D;  3RB9 A;  3LX2 A;  3V61 B;  2ZVM A;  3D1E A;  1DML A;  4K3L A;  3FDS C;  4L6P A;  3Q4J A;  4N9A A;  2XUR A;  3K4X A;  1VYM A;  2IX2 B;  1GE8 A;  3V60 B;  3A1J B;  4MJQ A;  3GGR B;  5HAC A;  5AGV A;  4OVH A;  1IZ4 A;  5AGU A;  1U7B A;  2ZVL A;  1ISQ A;  1U76 A;  5A6D A;  2NTI A;  5B7O A;  3Q4K A;  3P16 A;  4L60 A;  3Q4L A;  3A1J A;  3PGE B;  1SXJ F;  3U5Z F;  4K3Q A;  3LX1 A;  1UL1 A;  3GPN A;  5AH4 A;  4HK1 A;  4PNW A;  4N94 A;  1PLR A;  2AWA A;  3D1F A;  3HSL X;  2Z0L A;  1RWZ A;  2NTI B;  3FDS D;  1W60 A;  4ZTD A;  4MJP A;  2IZO C;  4PNU A;  5FRQ A;  1RXZ A;  1PLQ A;  4K3M A;  4TR7 A;  3QSB B;  3TBL A;  4CS5 A;  5CFK A;  1RXM A;  1CZD A;  4S3I A;  4N95 A;  4K3P A;  3AIX A;  3G65 C;  1IZ5 A;  5AUJ A;  3A2F B;  3V62 B;  3T0P A;  4D2G A;  3L0X A;  3BEP A;  5E0V A;  5FVE A;  3L10 A;  3QSB A;  2ZVW A;  3L0W A;  1AXC A;  5AH2 A;  2IJX A;  2HII C;  3U61 F;  4K3O A;  1B8H A;  3AIZ C;  3WGW A;  3VKX A;  3AIX B;  1VPK A;  4TR8 A;  4K3R A;  2HIK C;  1YYP A;  5H0T A;  3I2M X;  3P83 A;  3G65 A;  4TSZ A;  5IY4 A;  3P91 A;  1MMI A;  1T6L A;  1B77 A;  1UNN A;  2ZVV A;  2IZO B;  3PWE A;  2HIK B;  5DA7 A;  4YHR A;  2IX2 C;  4N97 A;  4PNV A;  3HI8 A;  3P87 A;  4K3K A;  3A1J C;  2HII A;  1JQL A;  4OVF A;  3GGR C;  3D1G A;  3AIZ A;  3F1V A;  4MJR A;  3G65 B;  2IO4 A;  4TRT A;  4RKI A;  1UD9 A;  2HIK A;  4TR6 A;  4N98 A;  1VYJ A;  3F1W A;  3IFV A;  2ZVK A;  1OK7 A;  4K3S A;  4N99 A;  5DAI A;  4OVG A;  2HII B;  4N96 A;  5IWD A;  2IX2 A;  3GPM A;  4K74 A;  2IO4 B;  3U60 F;  1JQJ A;  4RJF A;  5E0T A;  3GGR A;  2NTI C;  2AVT A;  5IXA A;  2POL A;  5E0U A;  2OD8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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