2AWA | Genus

Total Genus 94

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	94
sequence length	377
structure length	377
Chain Sequence	MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGITLIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQNQIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRPILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDDIETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSMERARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYLIDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRT

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 377 atoms

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377 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transferase
source organism	Streptococcus pneumoniae
publication title	Crystal structure of DNA polymerase III, beta chain (EC 2.7.7.7) (np_344555.1) from STREPTOCOCCUS PNEUMONIAE TIGR4 at 2.50 A resolution rcsb
molecule keywords	DNA polymerase III, beta chain
total genus	94
structure length	377
sequence length	377
chains with identical sequence	B, C, D
ec nomenclature	ec 2.7.7.7: DNA-directed DNA polymerase.
pdb deposition date	2005-08-31

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00712	DNA_pol3_beta	DNA polymerase III beta subunit, N-terminal domain
A	PF02767	DNA_pol3_beta_2	DNA polymerase III beta subunit, central domain
A	PF02768	DNA_pol3_beta_3	DNA polymerase III beta subunit, C-terminal domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.10.150.10	Alpha Beta	Roll	DNA Polymerase III; Chain A, domain 2	DNA Polymerase III, subunit A, domain 2	2awaA01
3.70.10.10	Alpha Beta	Box	Proliferating Cell Nuclear Antigen	Proliferating Cell Nuclear Antigen	2awaA02

3T0PA 4K3MA 3G65A 2IZOC 2IX2B 3V60B 5FRQA 3LX1A 4HK1A 4K3RA 2NTIA 1ISQA 1PLQA 4TR8A 1U76A 4D2GA 4CS5A 3D1FA 3GPMA 4N98A 3Q4KA 3F1WA 1IZ5A 3AIZC 2IJXA 4K3KA 3RB9A 4OVFA 3A1JC 5HACA 3L0XA 1PLRA 3U61F 3I2MX 1IZ4A 2IZOB 4YHRA 4TSZA 2Z0LA 2ZVVA 3P16A 2HIKC 2POLA 4K3SA 2HIIB 3GGRA 1VYMA 2HIIA 4MJQA 1VYJA 5AH2A 2ZVLA 3P83A 4MJRA 3AIXB 4TRTA 4ZTDA 3HSLX 4MJPA 1RXZA 2IX2A 5E0VA 2IO4B 5E0TA 5E0UA 3PWEA 4N97A 1GE8A 1JQLA 4N95A 2IO4A 2HIKB 3P87A 1T6LA 4PNVA 4K3OA 3Q4JA 2HIKA 3V62B 5H0TA 5AUJA 3K4XA 4K74A 3V61B 4N96A 1VPKA 1W60A 3F1VA 2ZVMA 1MMIA 2AWAA 3U60F 4K3PA 3VKXA 4N94A 3G65C 5DA7A 1U7BA 4PNWA 2NTIC 3A2FB 4L6PA 1RWZA 3A1JB 3Q4LA 3AIZA 3AIXA 4OVHA 3WGWA 5IWDA 3P91A 2ZVKA 3A1JA 1DMLA 3TBLA 4N9AA 3BEPA 4N99A 5AGUA 3IFVA 3D1GA 5FVEA 1CZDA 4PNUA 1OK7A 3FDSD 3G65B 3D1EA 1B8HA 1B77A 5AGVA 5JNED 1SXJF 4TR7A 3L0WA 2NTIB 1JQJA 3GGRC 5IY4A 5B7OA 1YYPA 2HIIC 2OD8A 3PGEB 2ZVWA 3GPNA 1AXCA 3U5ZF 2XURA 2IX2C 5DAIA 4RKIA 3LX2A 3L10A 4RJFA 5CFKA 4S3IA 3HI8A 4K3LA 5A6DA 3QSBB 5AH4A 4L60A 1UL1A 1UD9A 1UNNA 2AVTA 3GGRB 4OVGA 5IXAA 4K3QA 3FDSC 3QSBA 1RXMA 4TR6A
chains in the Genus database with same CATH superfamily

3T0PA 4K3MA 3G65A 2IZOC 2IX2B 3V60B 5FRQA 3LX1A 4HK1A 4K3RA 2NTIA 1ISQA 1PLQA 4TR8A 1U76A 4D2GA 4CS5A 3D1FA 3GPMA 4N98A 3Q4KA 3F1WA 1IZ5A 3AIZC 2IJXA 4K3KA 3RB9A 4OVFA 3A1JC 5HACA 3L0XA 1PLRA 3U61F 3I2MX 1IZ4A 2IZOB 4YHRA 4TSZA 2Z0LA 2ZVVA 3P16A 2HIKC 2POLA 4K3SA 2HIIB 3GGRA 1VYMA 2HIIA 4MJQA 1VYJA 5AH2A 2ZVLA 3P83A 4MJRA 3AIXB 4TRTA 4ZTDA 3HSLX 4MJPA 1RXZA 2IX2A 5E0VA 2IO4B 5E0TA 5E0UA 3PWEA 4N97A 1GE8A 1JQLA 4N95A 2IO4A 2HIKB 3P87A 1T6LA 4PNVA 4K3OA 3Q4JA 2HIKA 3V62B 5H0TA 3L0WB 5AUJA 3K4XA 4K74A 3V61B 4N96A 1VPKA 1W60A 3F1VA 2ZVMA 1MMIA 2AWAA 3U60F 4K3PA 3VKXA 4N94A 3G65C 5DA7A 1U7BA 4PNWA 2NTIC 3A2FB 4L6PA 1RWZA 3A1JB 3Q4LA 3AIZA 3AIXA 4OVHA 3WGWA 5IWDA 3P91A 2ZVKA 3A1JA 1DMLA 3TBLA 4N9AA 3BEPA 4N99A 5AGUA 3IFVA 3D1GA 5FVEA 1CZDA 4PNUA 1OK7A 3FDSD 3G65B 3D1EA 1B8HA 1B77A 5AGVA 5JNED 1SXJF 4TR7A 3L0WA 2NTIB 1JQJA 3GGRC 5IY4A 5B7OA 1YYPA 2HIIC 2OD8A 3PGEB 2ZVWA 3GPNA 1AXCA 3PGEA 3L10B 3U5ZF 2XURA 2IX2C 5DAIA 4RKIA 3L0XB 3LX2A 3L10A 4RJFA 5CFKA 4S3IA 3HI8A 4K3LA 5A6DA 3QSBB 5AH4A 4L60A 1UL1A 1UD9A 1UNNA 2AVTA 3GGRB 4OVGA 5IXAA 4K3QA 3FDSC 3QSBA 1RXMA 4TR6A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 3T0P A;  4K3M A;  3G65 A;  2IZO C;  2IX2 B;  3V60 B;  5FRQ A;  3LX1 A;  4HK1 A;  4K3R A;  2NTI A;  1ISQ A;  1PLQ A;  4TR8 A;  1U76 A;  4D2G A;  4CS5 A;  3D1F A;  3GPM A;  4N98 A;  3Q4K A;  3F1W A;  1IZ5 A;  3AIZ C;  2IJX A;  4K3K A;  3RB9 A;  4OVF A;  3A1J C;  5HAC A;  3L0X A;  1PLR A;  3U61 F;  3I2M X;  1IZ4 A;  2IZO B;  4YHR A;  4TSZ A;  2Z0L A;  2ZVV A;  3P16 A;  2HIK C;  2POL A;  4K3S A;  2HII B;  3GGR A;  1VYM A;  2HII A;  4MJQ A;  1VYJ A;  5AH2 A;  2ZVL A;  3P83 A;  4MJR A;  3AIX B;  4TRT A;  4ZTD A;  3HSL X;  4MJP A;  1RXZ A;  2IX2 A;  5E0V A;  2IO4 B;  5E0T A;  5E0U A;  3PWE A;  4N97 A;  1GE8 A;  1JQL A;  4N95 A;  2IO4 A;  2HIK B;  3P87 A;  1T6L A;  4PNV A;  4K3O A;  3Q4J A;  2HIK A;  3V62 B;  5H0T A;  5AUJ A;  3K4X A;  4K74 A;  3V61 B;  4N96 A;  1VPK A;  1W60 A;  3F1V A;  2ZVM A;  1MMI A;  2AWA A;  3U60 F;  4K3P A;  3VKX A;  4N94 A;  3G65 C;  5DA7 A;  1U7B A;  4PNW A;  2NTI C;  3A2F B;  4L6P A;  1RWZ A;  3A1J B;  3Q4L A;  3AIZ A;  3AIX A;  4OVH A;  3WGW A;  5IWD A;  3P91 A;  2ZVK A;  3A1J A;  1DML A;  3TBL A;  4N9A A;  3BEP A;  4N99 A;  5AGU A;  3IFV A;  3D1G A;  5FVE A;  1CZD A;  4PNU A;  1OK7 A;  3FDS D;  3G65 B;  3D1E A;  1B8H A;  1B77 A;  5AGV A;  5JNE D;  1SXJ F;  4TR7 A;  3L0W A;  2NTI B;  1JQJ A;  3GGR C;  5IY4 A;  5B7O A;  1YYP A;  2HII C;  2OD8 A;  3PGE B;  2ZVW A;  3GPN A;  1AXC A;  3U5Z F;  2XUR A;  2IX2 C;  5DAI A;  4RKI A;  3LX2 A;  3L10 A;  4RJF A;  5CFK A;  4S3I A;  3HI8 A;  4K3L A;  5A6D A;  3QSB B;  5AH4 A;  4L60 A;  1UL1 A;  1UD9 A;  1UNN A;  2AVT A;  3GGR B;  4OVG A;  5IXA A;  4K3Q A;  3FDS C;  3QSB A;  1RXM A;  4TR6 A; 
#chains in the Genus database with same CATH topology
 3T0P A;  4K3M A;  3G65 A;  2IZO C;  2IX2 B;  3V60 B;  5FRQ A;  3LX1 A;  4HK1 A;  4K3R A;  2NTI A;  1ISQ A;  1PLQ A;  4TR8 A;  1U76 A;  4D2G A;  4CS5 A;  3D1F A;  3GPM A;  4N98 A;  3Q4K A;  3F1W A;  1IZ5 A;  3AIZ C;  2IJX A;  4K3K A;  3RB9 A;  4OVF A;  3A1J C;  5HAC A;  3L0X A;  1PLR A;  3U61 F;  3I2M X;  1IZ4 A;  2IZO B;  4YHR A;  4TSZ A;  2Z0L A;  2ZVV A;  3P16 A;  2HIK C;  2POL A;  4K3S A;  2HII B;  3GGR A;  1VYM A;  2HII A;  4MJQ A;  1VYJ A;  5AH2 A;  2ZVL A;  3P83 A;  4MJR A;  3AIX B;  4TRT A;  4ZTD A;  3HSL X;  4MJP A;  1RXZ A;  2IX2 A;  5E0V A;  2IO4 B;  5E0T A;  5E0U A;  3PWE A;  4N97 A;  1GE8 A;  1JQL A;  4N95 A;  2IO4 A;  2HIK B;  3P87 A;  1T6L A;  4PNV A;  4K3O A;  3Q4J A;  2HIK A;  3V62 B;  5H0T A;  3L0W B;  5AUJ A;  3K4X A;  4K74 A;  3V61 B;  4N96 A;  1VPK A;  1W60 A;  3F1V A;  2ZVM A;  1MMI A;  2AWA A;  3U60 F;  4K3P A;  3VKX A;  4N94 A;  3G65 C;  5DA7 A;  1U7B A;  4PNW A;  2NTI C;  3A2F B;  4L6P A;  1RWZ A;  3A1J B;  3Q4L A;  3AIZ A;  3AIX A;  4OVH A;  3WGW A;  5IWD A;  3P91 A;  2ZVK A;  3A1J A;  1DML A;  3TBL A;  4N9A A;  3BEP A;  4N99 A;  5AGU A;  3IFV A;  3D1G A;  5FVE A;  1CZD A;  4PNU A;  1OK7 A;  3FDS D;  3G65 B;  3D1E A;  1B8H A;  1B77 A;  5AGV A;  5JNE D;  1SXJ F;  4TR7 A;  3L0W A;  2NTI B;  1JQJ A;  3GGR C;  5IY4 A;  5B7O A;  1YYP A;  2HII C;  2OD8 A;  3PGE B;  2ZVW A;  3GPN A;  1AXC A;  3PGE A;  3L10 B;  3U5Z F;  2XUR A;  2IX2 C;  5DAI A;  4RKI A;  3L0X B;  3LX2 A;  3L10 A;  4RJF A;  5CFK A;  4S3I A;  3HI8 A;  4K3L A;  5A6D A;  3QSB B;  5AH4 A;  4L60 A;  1UL1 A;  1UD9 A;  1UNN A;  2AVT A;  3GGR B;  4OVG A;  5IXA A;  4K3Q A;  3FDS C;  3QSB A;  1RXM A;  4TR6 A; 
#chains in the Genus database with same CATH homology
 3T0P A;  4K3M A;  3G65 A;  2IZO C;  2IX2 B;  3V60 B;  5FRQ A;  3LX1 A;  4HK1 A;  4K3R A;  2NTI A;  1ISQ A;  1PLQ A;  4TR8 A;  1U76 A;  4D2G A;  4CS5 A;  3D1F A;  3GPM A;  4N98 A;  3Q4K A;  3F1W A;  1IZ5 A;  3AIZ C;  2IJX A;  4K3K A;  3RB9 A;  4OVF A;  3A1J C;  5HAC A;  3L0X A;  1PLR A;  3U61 F;  3I2M X;  1IZ4 A;  2IZO B;  4YHR A;  4TSZ A;  2Z0L A;  2ZVV A;  3P16 A;  2HIK C;  2POL A;  4K3S A;  2HII B;  3GGR A;  1VYM A;  2HII A;  4MJQ A;  1VYJ A;  5AH2 A;  2ZVL A;  3P83 A;  4MJR A;  3AIX B;  4TRT A;  4ZTD A;  3HSL X;  4MJP A;  1RXZ A;  2IX2 A;  5E0V A;  2IO4 B;  5E0T A;  5E0U A;  3PWE A;  4N97 A;  1GE8 A;  1JQL A;  4N95 A;  2IO4 A;  2HIK B;  3P87 A;  1T6L A;  4PNV A;  4K3O A;  3Q4J A;  2HIK A;  3V62 B;  5H0T A;  5AUJ A;  3K4X A;  4K74 A;  3V61 B;  4N96 A;  1VPK A;  1W60 A;  3F1V A;  2ZVM A;  1MMI A;  2AWA A;  3U60 F;  4K3P A;  3VKX A;  4N94 A;  3G65 C;  5DA7 A;  1U7B A;  4PNW A;  2NTI C;  3A2F B;  4L6P A;  1RWZ A;  3A1J B;  3Q4L A;  3AIZ A;  3AIX A;  4OVH A;  3WGW A;  5IWD A;  3P91 A;  2ZVK A;  3A1J A;  1DML A;  3TBL A;  4N9A A;  3BEP A;  4N99 A;  5AGU A;  3IFV A;  3D1G A;  5FVE A;  1CZD A;  4PNU A;  1OK7 A;  3FDS D;  3G65 B;  3D1E A;  1B8H A;  1B77 A;  5AGV A;  5JNE D;  1SXJ F;  4TR7 A;  3L0W A;  2NTI B;  1JQJ A;  3GGR C;  5IY4 A;  5B7O A;  1YYP A;  2HII C;  2OD8 A;  3PGE B;  2ZVW A;  3GPN A;  1AXC A;  3U5Z F;  2XUR A;  2IX2 C;  5DAI A;  4RKI A;  3LX2 A;  3L10 A;  4RJF A;  5CFK A;  4S3I A;  3HI8 A;  4K3L A;  5A6D A;  3QSB B;  5AH4 A;  4L60 A;  1UL1 A;  1UD9 A;  1UNN A;  2AVT A;  3GGR B;  4OVG A;  5IXA A;  4K3Q A;  3FDS C;  3QSB A;  1RXM A;  4TR6 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2AWAA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations