2AWA | Genus

Total Genus 94

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	94
sequence length	377
structure length	377
Chain Sequence	MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGITLIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQNQIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRPILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDDIETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSMERARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYLIDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRT

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 377 atoms

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377 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Crystal structure of DNA polymerase III, beta chain (EC 2.7.7.7) (np_344555.1) from STREPTOCOCCUS PNEUMONIAE TIGR4 at 2.50 A resolution rcsb
molecule keywords	DNA polymerase III, beta chain
molecule tags	Transferase
source organism	Streptococcus pneumoniae
total genus	94
structure length	377
sequence length	377
chains with identical sequence	B, C, D
ec nomenclature	ec 2.7.7.7: DNA-directed DNA polymerase.
pdb deposition date	2005-08-31

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00712	DNA_pol3_beta	DNA polymerase III beta subunit, N-terminal domain
A	PF02767	DNA_pol3_beta_2	DNA polymerase III beta subunit, central domain
A	PF02768	DNA_pol3_beta_3	DNA polymerase III beta subunit, C-terminal domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.10.150.10	Alpha Beta	Roll	DNA Polymerase III; Chain A, domain 2	DNA Polymerase III, subunit A, domain 2	2awaA01
3.70.10.10	Alpha Beta	Box	Proliferating Cell Nuclear Antigen	Proliferating Cell Nuclear Antigen	2awaA02

4PNUA 1VYJA 2NTIA 5DA7A 2XURA 4MJQA 1IZ4A 3BEPA 4N99A 3V60B 3U61F 3AIXA 4CS5A 2IO4B 1DMLA 5CFKA 2IJXA 4L60A 1UL1A 3IFVA 1CZDA 1T6LA 4K3SA 5B7OA 2ZVLA 3LX1A 3T0PA 1UD9A 4N9AA 4K3OA 5E0TA 3TBLA 4N98A 1AXCA 2IX2B 5E0UA 5A6DA 5DAIA 1W60A 4OVGA 4K3MA 4OVFA 4S3IA 1U76A 4YHRA 1OK7A 2ZVKA 4K3PA 3A1JB 3D1EA 4ZTDA 3QSBA 3L10A 2IO4A 3HI8A 4TSZA 4MJRA 2IZOB 4PNVA 3FDSD 4RJFA 1JQLA 4TR8A 2POLA 5JNED 2HIIA 3P87A 3AIZC 3HSLX 1B77A 4K3KA 3K4XA 1SXJF 2IX2C 3GGRA 3FDSC 3GPNA 1VYMA 2AWAA 2ZVVA 3G65B 4PNWA 5FVEA 3PGEB 3GPMA 4HK1A 1IZ5A 2HIKA 3V62B 3VKXA 3L0XA 5AH2A 3A1JC 4TR7A 2NTIB 2ZVMA 2IZOC 3Q4JA 3D1FA 3F1VA 3P16A 1RXMA 1RWZA 3P83A 3AIZA 1JQJA 5AH4A 5FRQA 4TRTA 4D2GA 3I2MX 4TR6A 5AGUA 3RB9A 2IX2A 5AGVA 5HACA 1B8HA 1GE8A 3G65C 5E0VA 2AVTA 3F1WA 1UNNA 3U5ZF 3P91A 4MJPA 4K3QA 3A1JA 4N95A 3D1GA 5AUJA 3WGWA 4OVHA 2NTIC 3L0WA 3QSBB 1PLRA 3Q4LA 2ZVWA 1YYPA 4N96A 5H0TA 4K74A 5IXAA 3AIXB 2HIIC 4L6PA 3U60F 2HIIB 1MMIA 2OD8A 3PWEA 4N94A 4N97A 3V61B 4RKIA 4K3LA 3LX2A 1PLQA 5IY4A 3Q4KA 1U7BA 5IWDA 3GGRC 1VPKA 3GGRB 1RXZA 3G65A 2Z0LA 1ISQA 2HIKC 3A2FB 4K3RA 2HIKB
chains in the Genus database with same CATH superfamily

4PNUA 1VYJA 2NTIA 3L0XB 5DA7A 2XURA 4MJQA 1IZ4A 3BEPA 4N99A 3L10B 3V60B 3AIXA 4CS5A 2IO4B 1DMLA 3U61F 5CFKA 2IJXA 4L60A 1UL1A 3IFVA 1CZDA 1T6LA 4K3SA 5B7OA 2ZVLA 3LX1A 3T0PA 1UD9A 4N9AA 4K3OA 5E0TA 3TBLA 4N98A 1AXCA 2IX2B 5E0UA 5A6DA 5DAIA 1W60A 4OVGA 4K3MA 4OVFA 4S3IA 1U76A 4YHRA 1OK7A 2ZVKA 4K3PA 3A1JB 3D1EA 4ZTDA 3QSBA 3L10A 3L0WB 2IO4A 3HI8A 4TSZA 4MJRA 2IZOB 4PNVA 3FDSD 4RJFA 1JQLA 4TR8A 2POLA 5JNED 2HIIA 3P87A 3AIZC 3HSLX 1B77A 4K3KA 3K4XA 1SXJF 2IX2C 3GGRA 3FDSC 3GPNA 1VYMA 2AWAA 2ZVVA 3G65B 4PNWA 5FVEA 3PGEB 3GPMA 4HK1A 1IZ5A 2HIKA 3V62B 3VKXA 3L0XA 5AH2A 3A1JC 4TR7A 2NTIB 2ZVMA 2IZOC 3Q4JA 3D1FA 3F1VA 3P16A 1RXMA 1RWZA 3P83A 3AIZA 1JQJA 5AH4A 5FRQA 4TRTA 4D2GA 3I2MX 4TR6A 5AGUA 3RB9A 2IX2A 5AGVA 5HACA 3PGEA 1B8HA 1GE8A 3G65C 5E0VA 2AVTA 3F1WA 1UNNA 3U5ZF 3P91A 4MJPA 4K3QA 3A1JA 4N95A 3D1GA 5AUJA 3WGWA 4OVHA 2NTIC 3L0WA 3QSBB 1PLRA 3Q4LA 2ZVWA 1YYPA 4N96A 5H0TA 4K74A 5IXAA 3AIXB 2HIIC 4L6PA 3U60F 2HIIB 1MMIA 2OD8A 3PWEA 4N94A 4N97A 3V61B 4RKIA 4K3LA 3LX2A 1PLQA 5IY4A 3Q4KA 1U7BA 5IWDA 3GGRC 1VPKA 3GGRB 1RXZA 3G65A 2Z0LA 1ISQA 2HIKC 3A2FB 4K3RA 2HIKB
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4PNU A;  1VYJ A;  2NTI A;  5DA7 A;  2XUR A;  4MJQ A;  1IZ4 A;  3BEP A;  4N99 A;  3V60 B;  3U61 F;  3AIX A;  4CS5 A;  2IO4 B;  1DML A;  5CFK A;  2IJX A;  4L60 A;  1UL1 A;  3IFV A;  1CZD A;  1T6L A;  4K3S A;  5B7O A;  2ZVL A;  3LX1 A;  3T0P A;  1UD9 A;  4N9A A;  4K3O A;  5E0T A;  3TBL A;  4N98 A;  1AXC A;  2IX2 B;  5E0U A;  5A6D A;  5DAI A;  1W60 A;  4OVG A;  4K3M A;  4OVF A;  4S3I A;  1U76 A;  4YHR A;  1OK7 A;  2ZVK A;  4K3P A;  3A1J B;  3D1E A;  4ZTD A;  3QSB A;  3L10 A;  2IO4 A;  3HI8 A;  4TSZ A;  4MJR A;  2IZO B;  4PNV A;  3FDS D;  4RJF A;  1JQL A;  4TR8 A;  2POL A;  5JNE D;  2HII A;  3P87 A;  3AIZ C;  3HSL X;  1B77 A;  4K3K A;  3K4X A;  1SXJ F;  2IX2 C;  3GGR A;  3FDS C;  3GPN A;  1VYM A;  2AWA A;  2ZVV A;  3G65 B;  4PNW A;  5FVE A;  3PGE B;  3GPM A;  4HK1 A;  1IZ5 A;  2HIK A;  3V62 B;  3VKX A;  3L0X A;  5AH2 A;  3A1J C;  4TR7 A;  2NTI B;  2ZVM A;  2IZO C;  3Q4J A;  3D1F A;  3F1V A;  3P16 A;  1RXM A;  1RWZ A;  3P83 A;  3AIZ A;  1JQJ A;  5AH4 A;  5FRQ A;  4TRT A;  4D2G A;  3I2M X;  4TR6 A;  5AGU A;  3RB9 A;  2IX2 A;  5AGV A;  5HAC A;  1B8H A;  1GE8 A;  3G65 C;  5E0V A;  2AVT A;  3F1W A;  1UNN A;  3U5Z F;  3P91 A;  4MJP A;  4K3Q A;  3A1J A;  4N95 A;  3D1G A;  5AUJ A;  3WGW A;  4OVH A;  2NTI C;  3L0W A;  3QSB B;  1PLR A;  3Q4L A;  2ZVW A;  1YYP A;  4N96 A;  5H0T A;  4K74 A;  5IXA A;  3AIX B;  2HII C;  4L6P A;  3U60 F;  2HII B;  1MMI A;  2OD8 A;  3PWE A;  4N94 A;  4N97 A;  3V61 B;  4RKI A;  4K3L A;  3LX2 A;  1PLQ A;  5IY4 A;  3Q4K A;  1U7B A;  5IWD A;  3GGR C;  1VPK A;  3GGR B;  1RXZ A;  3G65 A;  2Z0L A;  1ISQ A;  2HIK C;  3A2F B;  4K3R A;  2HIK B; 
#chains in the Genus database with same CATH topology
 4PNU A;  1VYJ A;  2NTI A;  3L0X B;  5DA7 A;  2XUR A;  4MJQ A;  1IZ4 A;  3BEP A;  4N99 A;  3L10 B;  3V60 B;  3AIX A;  4CS5 A;  2IO4 B;  1DML A;  3U61 F;  5CFK A;  2IJX A;  4L60 A;  1UL1 A;  3IFV A;  1CZD A;  1T6L A;  4K3S A;  5B7O A;  2ZVL A;  3LX1 A;  3T0P A;  1UD9 A;  4N9A A;  4K3O A;  5E0T A;  3TBL A;  4N98 A;  1AXC A;  2IX2 B;  5E0U A;  5A6D A;  5DAI A;  1W60 A;  4OVG A;  4K3M A;  4OVF A;  4S3I A;  1U76 A;  4YHR A;  1OK7 A;  2ZVK A;  4K3P A;  3A1J B;  3D1E A;  4ZTD A;  3QSB A;  3L10 A;  3L0W B;  2IO4 A;  3HI8 A;  4TSZ A;  4MJR A;  2IZO B;  4PNV A;  3FDS D;  4RJF A;  1JQL A;  4TR8 A;  2POL A;  5JNE D;  2HII A;  3P87 A;  3AIZ C;  3HSL X;  1B77 A;  4K3K A;  3K4X A;  1SXJ F;  2IX2 C;  3GGR A;  3FDS C;  3GPN A;  1VYM A;  2AWA A;  2ZVV A;  3G65 B;  4PNW A;  5FVE A;  3PGE B;  3GPM A;  4HK1 A;  1IZ5 A;  2HIK A;  3V62 B;  3VKX A;  3L0X A;  5AH2 A;  3A1J C;  4TR7 A;  2NTI B;  2ZVM A;  2IZO C;  3Q4J A;  3D1F A;  3F1V A;  3P16 A;  1RXM A;  1RWZ A;  3P83 A;  3AIZ A;  1JQJ A;  5AH4 A;  5FRQ A;  4TRT A;  4D2G A;  3I2M X;  4TR6 A;  5AGU A;  3RB9 A;  2IX2 A;  5AGV A;  5HAC A;  3PGE A;  1B8H A;  1GE8 A;  3G65 C;  5E0V A;  2AVT A;  3F1W A;  1UNN A;  3U5Z F;  3P91 A;  4MJP A;  4K3Q A;  3A1J A;  4N95 A;  3D1G A;  5AUJ A;  3WGW A;  4OVH A;  2NTI C;  3L0W A;  3QSB B;  1PLR A;  3Q4L A;  2ZVW A;  1YYP A;  4N96 A;  5H0T A;  4K74 A;  5IXA A;  3AIX B;  2HII C;  4L6P A;  3U60 F;  2HII B;  1MMI A;  2OD8 A;  3PWE A;  4N94 A;  4N97 A;  3V61 B;  4RKI A;  4K3L A;  3LX2 A;  1PLQ A;  5IY4 A;  3Q4K A;  1U7B A;  5IWD A;  3GGR C;  1VPK A;  3GGR B;  1RXZ A;  3G65 A;  2Z0L A;  1ISQ A;  2HIK C;  3A2F B;  4K3R A;  2HIK B; 
#chains in the Genus database with same CATH homology
 4PNU A;  1VYJ A;  2NTI A;  5DA7 A;  2XUR A;  4MJQ A;  1IZ4 A;  3BEP A;  4N99 A;  3V60 B;  3U61 F;  3AIX A;  4CS5 A;  2IO4 B;  1DML A;  5CFK A;  2IJX A;  4L60 A;  1UL1 A;  3IFV A;  1CZD A;  1T6L A;  4K3S A;  5B7O A;  2ZVL A;  3LX1 A;  3T0P A;  1UD9 A;  4N9A A;  4K3O A;  5E0T A;  3TBL A;  4N98 A;  1AXC A;  2IX2 B;  5E0U A;  5A6D A;  5DAI A;  1W60 A;  4OVG A;  4K3M A;  4OVF A;  4S3I A;  1U76 A;  4YHR A;  1OK7 A;  2ZVK A;  4K3P A;  3A1J B;  3D1E A;  4ZTD A;  3QSB A;  3L10 A;  2IO4 A;  3HI8 A;  4TSZ A;  4MJR A;  2IZO B;  4PNV A;  3FDS D;  4RJF A;  1JQL A;  4TR8 A;  2POL A;  5JNE D;  2HII A;  3P87 A;  3AIZ C;  3HSL X;  1B77 A;  4K3K A;  3K4X A;  1SXJ F;  2IX2 C;  3GGR A;  3FDS C;  3GPN A;  1VYM A;  2AWA A;  2ZVV A;  3G65 B;  4PNW A;  5FVE A;  3PGE B;  3GPM A;  4HK1 A;  1IZ5 A;  2HIK A;  3V62 B;  3VKX A;  3L0X A;  5AH2 A;  3A1J C;  4TR7 A;  2NTI B;  2ZVM A;  2IZO C;  3Q4J A;  3D1F A;  3F1V A;  3P16 A;  1RXM A;  1RWZ A;  3P83 A;  3AIZ A;  1JQJ A;  5AH4 A;  5FRQ A;  4TRT A;  4D2G A;  3I2M X;  4TR6 A;  5AGU A;  3RB9 A;  2IX2 A;  5AGV A;  5HAC A;  1B8H A;  1GE8 A;  3G65 C;  5E0V A;  2AVT A;  3F1W A;  1UNN A;  3U5Z F;  3P91 A;  4MJP A;  4K3Q A;  3A1J A;  4N95 A;  3D1G A;  5AUJ A;  3WGW A;  4OVH A;  2NTI C;  3L0W A;  3QSB B;  1PLR A;  3Q4L A;  2ZVW A;  1YYP A;  4N96 A;  5H0T A;  4K74 A;  5IXA A;  3AIX B;  2HII C;  4L6P A;  3U60 F;  2HII B;  1MMI A;  2OD8 A;  3PWE A;  4N94 A;  4N97 A;  3V61 B;  4RKI A;  4K3L A;  3LX2 A;  1PLQ A;  5IY4 A;  3Q4K A;  1U7B A;  5IWD A;  3GGR C;  1VPK A;  3GGR B;  1RXZ A;  3G65 A;  2Z0L A;  1ISQ A;  2HIK C;  3A2F B;  4K3R A;  2HIK B;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2AWAA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations