2C5ZA

Structure and ctd binding of the set2 sri domain
Total Genus 35
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
93
structure length
93
Chain Sequence
VSQSQRLEHNWNKFFASFVPNLIKKNPQSKQFDHENIKQCAKDIVKILTTKELKKDSSRAPPDDLTKGKRHKVKEFINSYMDKIILKKKQKKA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure and carboxyl-terminal domain (CTD) binding of the Set2 SRI domain that couples histone H3 Lys36 methylation to transcription.
pubmed doi rcsb
molecule tags Transcription
source organism Saccharomyces cerevisiae
molecule keywords SET DOMAIN PROTEIN 2
total genus 35
structure length 93
sequence length 93
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2005-11-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08236 SRI SRI (Set2 Rpb1 interacting) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1740.100 Mainly Alpha Orthogonal Bundle Rna Polymerase Sigma Factor; Chain: A Rna Polymerase Sigma Factor; Chain: A 2c5zA00
2A7OA 2C5ZA
chains in the Genus database with same CATH superfamily
3T0YA 2XQ0A 2JCXA 2PL5A 3ANNA 4MS6A 2R72A 4FLQA 4XN7A 1H3LA 4XMWA 5DYFA 1JGIA 4ZX5A 2A7OA 4XMXA 4PVBA 4FCAA 2FFLA 3CHSA 4AR9A 3B7RL 2PGGA 4K5PA 3QJXA 4ZQFA 5JMWA 2VLAA 3FUFA 4ZW8A 2HPTA 4A03A 5JBIA 4R5XA 5HNHA 4Q4EA 3FTZA 3B2PA 2WPGA 4X2UA 2QJ1A 3UEQA 5JNLA 2XPZA 5FWQA 3FTSA 4ZX6A 2ZXGA 3FTYA 5DLLA 1Q0HA 2JCVA 2HPOA 2R59A 4QIRA 2QVWA 2WZGA 2B61A 1SG7A 4GAEA 4QMEA 1R0LA 1MW0A 3B7TA 3CZKA 4Y67A 1MW1A 1ZS2A 2DQMA 4FLOA 3T8VA 1ONNA 4ZW7A 5JAZA 2VJ8A 3FUJA 5EV7A 2JD0A 4XMTA 3CXBA 3FULA 1G5AA 4XO4A 3WQRA 4QHPA 4ZW6A 4XNBA 4J3BA 4FLSA 4RVBA 1R0KA 3FHEA 2C82A 4FLRA 4L2LA 1SC5A 3CHRA 3AU8A 3B34A 2WZFA 1X3ZA 3FUNA 3FTXA 3FUDA 4OOFA 3ANMA 4XNAA 4AR1A 5BPPA 2EGHA 3CZEA 4LUPA 1OR7A 3VVLA 3HW2A 1ONPA 4RSYA 3A06A 2GTQA 3Q43A 3JT1A 3EBGA 3B7UX 3FU6A 3FUMA 4RCVA 3AU9A 1JVSA 4AR8A 4MKTA 2Y1GA 3B2XA 3FTVA 1MW3A 4XN4A 4KP7A 5DULA 3WQQA 2Y1EA 1K5HA 3FH5A 4XO3A 4XN1A 3CZLA 3FUIA 3ANLA 3RC3A 3ZI0A 4R7LA 4ZQGA 3ZHXA 4ZQEA 3ZHZA 4ZX4A 1H19A 5HNFA 3CIAA 1S46A 3RASA 4DPRA 2DQ6A 3FU5A 1T1RA 2JD1A 3B3BA 3JSZA 4Q4IA 4QUOA 3EBHA 4K5OA 2JV7A 3A14A 5JMPA 2MAPA 4K5NA 4ARFA 4ZQTA 3Q44A 4CXFA 2PUSA 1Q0LA 4NQWA 3RC8A 4K5LA 4GAAA 3CHQA 3ZHYA 3CHOA 3B37A 4XMZA 3FUEA 4R5TA 2O7GA 1RP3A 4Y6SA 4AYSA 3EBIA 3CHPA 3FTWA 4Y6PA 3WQSB 3FUHA 4R5VA 3UERA 3B7SA 4XN8A 4XMUA 3FU0A 3R0IA 4XN9A 4XMVA 2RJIA 2MAOA 1T1SA 2Y1CA 4PU2A 2Y1FA 4OOEA 4K5MA 3VVMA 1ONOA 3AUAA 3KEDA 4AICA 2JD2A 4ZX3A 1MW2A 4PW4A 5AENA 5HLTA 4Y6RA 1X3WA 1HS6A 1GW6A 2JCYA 4JNDA 4XNDA 1MVYA 3CZGA 3FUKA 4ZW3A 2Y1DA 4ZW5A 3FH8A 3IIEA 2XPYA 3U9WA 2C5ZA 1JG9A 4XN5A 3FH7A 5JC1A 4ZQHA 3FU3A 5JO0A 3PUUA 1Q0QA 4XO5A 4ZN6A 2R70A 3UCQA 4XN2A 4BKXA 3FTUA 1SQMA 4QPEA
chains in the Genus database with same CATH topology
3T0YA 2XQ0A 2JCXA 2PL5A 3ANNA 4MS6A 2R72A 4FLQA 4XN7A 1H3LA 4XMWA 5DYFA 1JGIA 4ZX5A 2A7OA 4XMXA 4PVBA 4FCAA 2FFLA 3CHSA 4AR9A 3B7RL 2PGGA 4K5PA 3QJXA 4ZQFA 5JMWA 2VLAA 3FUFA 4ZW8A 2HPTA 4A03A 5JBIA 4R5XA 5HNHA 4Q4EA 3FTZA 3B2PA 2WPGA 4X2UA 2QJ1A 3UEQA 5JNLA 2XPZA 5FWQA 3FTSA 4ZX6A 2ZXGA 3FTYA 5DLLA 1Q0HA 2JCVA 2HPOA 2R59A 4QIRA 2QVWA 2WZGA 2B61A 1SG7A 4GAEA 4QMEA 1R0LA 1MW0A 3B7TA 3CZKA 4Y67A 1MW1A 1ZS2A 2DQMA 4FLOA 3T8VA 1ONNA 4ZW7A 5JAZA 2VJ8A 3FUJA 5EV7A 2JD0A 4XMTA 3FULA 1G5AA 4XO4A 3WQRA 4QHPA 4ZW6A 4XNBA 4J3BA 4FLSA 4RVBA 1R0KA 3FHEA 2C82A 4FLRA 4L2LA 1SC5A 3CHRA 3AU8A 3B34A 2WZFA 1X3ZA 3FUNA 3FTXA 3FUDA 4OOFA 3ANMA 4XNAA 4AR1A 5BPPA 2EGHA 3CZEA 4LUPA 1OR7A 3VVLA 1ONPA 4RSYA 3A06A 2GTQA 3Q43A 3JT1A 3EBGA 3B7UX 3FU6A 3FUMA 4RCVA 3AU9A 1JVSA 4AR8A 4MKTA 2Y1GA 3B2XA 3FTVA 1MW3A 4XN4A 4KP7A 5DULA 3WQQA 2Y1EA 1K5HA 3FH5A 4XO3A 4XN1A 3CZLA 3FUIA 3ANLA 3RC3A 3ZI0A 4R7LA 4ZQGA 3ZHXA 4ZQEA 3ZHZA 4ZX4A 1H19A 5HNFA 3CIAA 1S46A 3RASA 4DPRA 2DQ6A 3FU5A 1T1RA 2JD1A 3B3BA 3JSZA 4Q4IA 4QUOA 3EBHA 4K5OA 2JV7A 3A14A 5JMPA 2MAPA 4K5NA 4ARFA 4ZQTA 3Q44A 4CXFA 2PUSA 1Q0LA 4NQWA 3RC8A 4K5LA 4GAAA 3CHQA 3ZHYA 3CHOA 3B37A 4XMZA 3FUEA 4R5TA 2O7GA 1RP3A 4Y6SA 4AYSA 3EBIA 3CHPA 3FTWA 4Y6PA 3WQSB 3FUHA 4R5VA 3UERA 3B7SA 4XN8A 4XMUA 3FU0A 3R0IA 4XN9A 4XMVA 2RJIA 2MAOA 1T1SA 2Y1CA 4PU2A 2Y1FA 4OOEA 4K5MA 3VVMA 1ONOA 3AUAA 3KEDA 4AICA 2JD2A 4ZX3A 1MW2A 4PW4A 5AENA 5HLTA 4Y6RA 1X3WA 1HS6A 1GW6A 2JCYA 4JNDA 4XNDA 1MVYA 3CZGA 3FUKA 4ZW3A 2Y1DA 4ZW5A 3FH8A 3IIEA 2XPYA 3U9WA 2C5ZA 1JG9A 4XN5A 3FH7A 5JC1A 4ZQHA 3FU3A 5JO0A 3PUUA 1Q0QA 4XO5A 4ZN6A 2R70A 3UCQA 4XN2A 4BKXA 3FTUA 1SQMA 4QPEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2A7O A;  2C5Z A; 
#chains in the Genus database with same CATH topology
 3T0Y A;  2XQ0 A;  2JCX A;  2PL5 A;  3ANN A;  4MS6 A;  2R72 A;  4FLQ A;  4XN7 A;  1H3L A;  4XMW A;  5DYF A;  1JGI A;  4ZX5 A;  2A7O A;  4XMX A;  4PVB A;  4FCA A;  2FFL A;  3CHS A;  4AR9 A;  3B7R L;  2PGG A;  4K5P A;  3QJX A;  4ZQF A;  5JMW A;  2VLA A;  3FUF A;  4ZW8 A;  2HPT A;  4A03 A;  5JBI A;  4R5X A;  5HNH A;  4Q4E A;  3FTZ A;  3B2P A;  2WPG A;  4X2U A;  2QJ1 A;  3UEQ A;  5JNL A;  2XPZ A;  5FWQ A;  3FTS A;  4ZX6 A;  2ZXG A;  3FTY A;  5DLL A;  1Q0H A;  2JCV A;  2HPO A;  2R59 A;  4QIR A;  2QVW A;  2WZG A;  2B61 A;  1SG7 A;  4GAE A;  4QME A;  1R0L A;  1MW0 A;  3B7T A;  3CZK A;  4Y67 A;  1MW1 A;  1ZS2 A;  2DQM A;  4FLO A;  3T8V A;  1ONN A;  4ZW7 A;  5JAZ A;  2VJ8 A;  3FUJ A;  5EV7 A;  2JD0 A;  4XMT A;  3CXB A;  3FUL A;  1G5A A;  4XO4 A;  3WQR A;  4QHP A;  4ZW6 A;  4XNB A;  4J3B A;  4FLS A;  4RVB A;  1R0K A;  3FHE A;  2C82 A;  4FLR A;  4L2L A;  1SC5 A;  3CHR A;  3AU8 A;  3B34 A;  2WZF A;  1X3Z A;  3FUN A;  3FTX A;  3FUD A;  4OOF A;  3ANM A;  4XNA A;  4AR1 A;  5BPP A;  2EGH A;  3CZE A;  4LUP A;  1OR7 A;  3VVL A;  3HW2 A;  1ONP A;  4RSY A;  3A06 A;  2GTQ A;  3Q43 A;  3JT1 A;  3EBG A;  3B7U X;  3FU6 A;  3FUM A;  4RCV A;  3AU9 A;  1JVS A;  4AR8 A;  4MKT A;  2Y1G A;  3B2X A;  3FTV A;  1MW3 A;  4XN4 A;  4KP7 A;  5DUL A;  3WQQ A;  2Y1E A;  1K5H A;  3FH5 A;  4XO3 A;  4XN1 A;  3CZL A;  3FUI A;  3ANL A;  3RC3 A;  3ZI0 A;  4R7L A;  4ZQG A;  3ZHX A;  4ZQE A;  3ZHZ A;  4ZX4 A;  1H19 A;  5HNF A;  3CIA A;  1S46 A;  3RAS A;  4DPR A;  2DQ6 A;  3FU5 A;  1T1R A;  2JD1 A;  3B3B A;  3JSZ A;  4Q4I A;  4QUO A;  3EBH A;  4K5O A;  2JV7 A;  3A14 A;  5JMP A;  2MAP A;  4K5N A;  4ARF A;  4ZQT A;  3Q44 A;  4CXF A;  2PUS A;  1Q0L A;  4NQW A;  3RC8 A;  4K5L A;  4GAA A;  3CHQ A;  3ZHY A;  3CHO A;  3B37 A;  4XMZ A;  3FUE A;  4R5T A;  2O7G A;  1RP3 A;  4Y6S A;  4AYS A;  3EBI A;  3CHP A;  3FTW A;  4Y6P A;  3WQS B;  3FUH A;  4R5V A;  3UER A;  3B7S A;  4XN8 A;  4XMU A;  3FU0 A;  3R0I A;  4XN9 A;  4XMV A;  2RJI A;  2MAO A;  1T1S A;  2Y1C A;  4PU2 A;  2Y1F A;  4OOE A;  4K5M A;  3VVM A;  1ONO A;  3AUA A;  3KED A;  4AIC A;  2JD2 A;  4ZX3 A;  1MW2 A;  4PW4 A;  5AEN A;  5HLT A;  4Y6R A;  1X3W A;  1HS6 A;  1GW6 A;  2JCY A;  4JND A;  4XND A;  1MVY A;  3CZG A;  3FUK A;  4ZW3 A;  2Y1D A;  4ZW5 A;  3FH8 A;  3IIE A;  2XPY A;  3U9W A;  2C5Z A;  1JG9 A;  4XN5 A;  3FH7 A;  5JC1 A;  4ZQH A;  3FU3 A;  5JO0 A;  3PUU A;  1Q0Q A;  4XO5 A;  4ZN6 A;  2R70 A;  3UCQ A;  4XN2 A;  4BKX A;  3FTU A;  1SQM A;  4QPE A; 
#chains in the Genus database with same CATH homology
 3T0Y A;  2XQ0 A;  2JCX A;  2PL5 A;  3ANN A;  4MS6 A;  2R72 A;  4FLQ A;  4XN7 A;  1H3L A;  4XMW A;  5DYF A;  1JGI A;  4ZX5 A;  2A7O A;  4XMX A;  4PVB A;  4FCA A;  2FFL A;  3CHS A;  4AR9 A;  3B7R L;  2PGG A;  4K5P A;  3QJX A;  4ZQF A;  5JMW A;  2VLA A;  3FUF A;  4ZW8 A;  2HPT A;  4A03 A;  5JBI A;  4R5X A;  5HNH A;  4Q4E A;  3FTZ A;  3B2P A;  2WPG A;  4X2U A;  2QJ1 A;  3UEQ A;  5JNL A;  2XPZ A;  5FWQ A;  3FTS A;  4ZX6 A;  2ZXG A;  3FTY A;  5DLL A;  1Q0H A;  2JCV A;  2HPO A;  2R59 A;  4QIR A;  2QVW A;  2WZG A;  2B61 A;  1SG7 A;  4GAE A;  4QME A;  1R0L A;  1MW0 A;  3B7T A;  3CZK A;  4Y67 A;  1MW1 A;  1ZS2 A;  2DQM A;  4FLO A;  3T8V A;  1ONN A;  4ZW7 A;  5JAZ A;  2VJ8 A;  3FUJ A;  5EV7 A;  2JD0 A;  4XMT A;  3FUL A;  1G5A A;  4XO4 A;  3WQR A;  4QHP A;  4ZW6 A;  4XNB A;  4J3B A;  4FLS A;  4RVB A;  1R0K A;  3FHE A;  2C82 A;  4FLR A;  4L2L A;  1SC5 A;  3CHR A;  3AU8 A;  3B34 A;  2WZF A;  1X3Z A;  3FUN A;  3FTX A;  3FUD A;  4OOF A;  3ANM A;  4XNA A;  4AR1 A;  5BPP A;  2EGH A;  3CZE A;  4LUP A;  1OR7 A;  3VVL A;  1ONP A;  4RSY A;  3A06 A;  2GTQ A;  3Q43 A;  3JT1 A;  3EBG A;  3B7U X;  3FU6 A;  3FUM A;  4RCV A;  3AU9 A;  1JVS A;  4AR8 A;  4MKT A;  2Y1G A;  3B2X A;  3FTV A;  1MW3 A;  4XN4 A;  4KP7 A;  5DUL A;  3WQQ A;  2Y1E A;  1K5H A;  3FH5 A;  4XO3 A;  4XN1 A;  3CZL A;  3FUI A;  3ANL A;  3RC3 A;  3ZI0 A;  4R7L A;  4ZQG A;  3ZHX A;  4ZQE A;  3ZHZ A;  4ZX4 A;  1H19 A;  5HNF A;  3CIA A;  1S46 A;  3RAS A;  4DPR A;  2DQ6 A;  3FU5 A;  1T1R A;  2JD1 A;  3B3B A;  3JSZ A;  4Q4I A;  4QUO A;  3EBH A;  4K5O A;  2JV7 A;  3A14 A;  5JMP A;  2MAP A;  4K5N A;  4ARF A;  4ZQT A;  3Q44 A;  4CXF A;  2PUS A;  1Q0L A;  4NQW A;  3RC8 A;  4K5L A;  4GAA A;  3CHQ A;  3ZHY A;  3CHO A;  3B37 A;  4XMZ A;  3FUE A;  4R5T A;  2O7G A;  1RP3 A;  4Y6S A;  4AYS A;  3EBI A;  3CHP A;  3FTW A;  4Y6P A;  3WQS B;  3FUH A;  4R5V A;  3UER A;  3B7S A;  4XN8 A;  4XMU A;  3FU0 A;  3R0I A;  4XN9 A;  4XMV A;  2RJI A;  2MAO A;  1T1S A;  2Y1C A;  4PU2 A;  2Y1F A;  4OOE A;  4K5M A;  3VVM A;  1ONO A;  3AUA A;  3KED A;  4AIC A;  2JD2 A;  4ZX3 A;  1MW2 A;  4PW4 A;  5AEN A;  5HLT A;  4Y6R A;  1X3W A;  1HS6 A;  1GW6 A;  2JCY A;  4JND A;  4XND A;  1MVY A;  3CZG A;  3FUK A;  4ZW3 A;  2Y1D A;  4ZW5 A;  3FH8 A;  3IIE A;  2XPY A;  3U9W A;  2C5Z A;  1JG9 A;  4XN5 A;  3FH7 A;  5JC1 A;  4ZQH A;  3FU3 A;  5JO0 A;  3PUU A;  1Q0Q A;  4XO5 A;  4ZN6 A;  2R70 A;  3UCQ A;  4XN2 A;  4BKX A;  3FTU A;  1SQM A;  4QPE A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...