2C5ZA

Structure and ctd binding of the set2 sri domain
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
93
structure length
93
Chain Sequence
VSQSQRLEHNWNKFFASFVPNLIKKNPQSKQFDHENIKQCAKDIVKILTTKELKKDSSRAPPDDLTKGKRHKVKEFINSYMDKIILKKKQKKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transcription
source organism Saccharomyces cerevisiae
publication title Structure and carboxyl-terminal domain (CTD) binding of the Set2 SRI domain that couples histone H3 Lys36 methylation to transcription.
pubmed doi rcsb
molecule keywords SET DOMAIN PROTEIN 2
total genus 35
structure length 93
sequence length 93
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2005-11-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08236 SRI SRI (Set2 Rpb1 interacting) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1740.100 Mainly Alpha Orthogonal Bundle Rna Polymerase Sigma Factor; Chain: A Rna Polymerase Sigma Factor; Chain: A 2c5zA00
2C5ZA 2A7OA
chains in the Genus database with same CATH superfamily
4XNAA 4XN5A 3B2XA 4KP7A 3CZEA 2MAOA 3FU6A 2Y1DA 4FLQA 4K5NA 4PW4A 3AU8A 3PUUA 4Y6RA 4XO4A 4QUOA 4X2UA 2XPYA 3FUFA 2RJIA 5HNHA 4L2LA 1H19A 4ZX5A 4GAEA 3EBGA 3CZKA 1R0KA 4XN4A 3T8VA 3CHSA 5DLLA 4R5VA 4A03A 2GTQA 4K5MA 5EV7A 3JSZA 3FULA 4Y6SA 3FTVA 4XN8A 1MW3A 2XQ0A 3HW2A 2R70A 3B2PA 2Y1GA 5JBIA 3RC8A 2Y1EA 4XN2A 5JO0A 2MAPA 1MW1A 5JNLA 3B7SA 3RC3A 1X3ZA 2JD1A 4FCAA 3WQRA 3CHPA 5HLTA 1MVYA 2PL5A 2DQMA 3FUHA 5JMWA 1RP3A 3Q43A 1ONNA 2JCXA 5DYFA 4XMZA 2JV7A 4ZQFA 2HPTA 1GW6A 4ZW5A 3A06A 4XNBA 4AYSA 3EBHA 4ZW8A 3ZHYA 2R72A 4ZW6A 3FH7A 1Q0LA 2O7GA 3CZLA 4XMUA 5FWQA 3T0YA 1JVSA 3CHRA 5JAZA 3VVLA 3FU3A 3FUMA 4R5XA 1ONPA 5BPPA 3R0IA 2FFLA 3FHEA 3U9WA 3FUDA 5DULA 4FLOA 4AICA 4QPEA 4XN9A 3B7TA 4XO3A 3B34A 1JG9A 3KEDA 4AR1A 1Q0HA 4RCVA 4K5OA 4RSYA 3FTYA 4ZX3A 4PVBA 1ONOA 1SG7A 2C82A 3FU5A 4XMTA 3Q44A 4AR9A 4BKXA 4XO5A 3ANNA 4ARFA 2ZXGA 3FTWA 3RASA 4QMEA 3B7UX 2R59A 4DPRA 2WPGA 4ZX6A 4GAAA 4ZQEA 4XMXA 3FUJA 3FUKA 1R0LA 4ZW3A 4XN7A 5JMPA 4XMVA 3B7RL 3FUEA 4ZN6A 3FTUA 4ZQTA 4NQWA 2DQ6A 2B61A 4XN1A 4ZQGA 4FLSA 5HNFA 4AR8A 4R7LA 3EBIA 2PUSA 1HS6A 3WQSB 2QJ1A 3FTSA 4Q4IA 3FUIA 2VJ8A 2C5ZA 2JCVA 4K5PA 4MKTA 2A7OA 3AUAA 3B37A 3FU0A 4OOEA 4R5TA 3CZGA 1JGIA 3IIEA 1Q0QA 2WZGA 3A14A 3CIAA 3JT1A 1OR7A 4K5LA 3ZI0A 1T1RA 2QVWA 1ZS2A 3CHOA 4PU2A 4OOFA 4Y67A 2Y1CA 3QJXA 2JCYA 4Q4EA 3FH8A 4XNDA 3ANMA 2WZFA 3FUNA 4Y6PA 3UCQA 2XPZA 3FTXA 3CXBA 2Y1FA 1T1SA 3FTZA 3UERA 3UEQA 3WQQA 5JC1A 3FH5A 3ZHXA 4QHPA 1MW2A 4MS6A 4CXFA 2EGHA 4FLRA 4ZX4A 3CHQA 2JD0A 4J3BA 4JNDA 5AENA 1G5AA 4LUPA 1X3WA 1SQMA 2HPOA 1K5HA 3AU9A 4ZQHA 3VVMA 3ZHZA 2VLAA 4RVBA 2JD2A 1SC5A 3B3BA 3ANLA 4QIRA 4XMWA 4ZW7A 1S46A 1H3LA 1MW0A 2PGGA
chains in the Genus database with same CATH topology
4XNAA 4XN5A 3B2XA 4KP7A 3CZEA 2MAOA 3FU6A 2Y1DA 4FLQA 4K5NA 4PW4A 3AU8A 3PUUA 4Y6RA 4XO4A 4QUOA 4X2UA 2XPYA 3FUFA 2RJIA 5HNHA 4L2LA 1H19A 4ZX5A 4GAEA 3EBGA 3CZKA 1R0KA 4XN4A 3T8VA 3CHSA 5DLLA 4R5VA 4A03A 2GTQA 4K5MA 5EV7A 3JSZA 3FULA 4Y6SA 3FTVA 4XN8A 1MW3A 2XQ0A 2R70A 3B2PA 2Y1GA 5JBIA 3RC8A 2Y1EA 4XN2A 5JO0A 2MAPA 1MW1A 5JNLA 3B7SA 3RC3A 1X3ZA 2JD1A 4FCAA 3WQRA 3CHPA 5HLTA 1MVYA 2PL5A 2DQMA 3FUHA 5JMWA 1RP3A 3Q43A 1ONNA 2JCXA 5DYFA 4XMZA 2JV7A 4ZQFA 2HPTA 1GW6A 4ZW5A 3A06A 4XNBA 4AYSA 3EBHA 4ZW8A 3ZHYA 2R72A 4ZW6A 3FH7A 1Q0LA 2O7GA 3CZLA 4XMUA 5FWQA 3T0YA 1JVSA 3CHRA 5JAZA 3VVLA 3FU3A 3FUMA 4R5XA 1ONPA 5BPPA 3R0IA 2FFLA 3FHEA 3U9WA 3FUDA 5DULA 4FLOA 4AICA 4QPEA 4XN9A 3B7TA 4XO3A 3B34A 1JG9A 3KEDA 4AR1A 1Q0HA 4RCVA 4K5OA 4RSYA 3FTYA 4ZX3A 4PVBA 1ONOA 1SG7A 2C82A 3FU5A 4XMTA 3Q44A 4AR9A 4BKXA 4XO5A 3ANNA 4ARFA 2ZXGA 3FTWA 3RASA 4QMEA 3B7UX 2R59A 4DPRA 2WPGA 4ZX6A 4GAAA 4ZQEA 4XMXA 3FUJA 3FUKA 1R0LA 4ZW3A 4XN7A 5JMPA 4XMVA 3B7RL 3FUEA 4ZN6A 3FTUA 4ZQTA 4NQWA 2DQ6A 2B61A 4XN1A 4ZQGA 4FLSA 5HNFA 4AR8A 4R7LA 3EBIA 2PUSA 1HS6A 3WQSB 2QJ1A 3FTSA 4Q4IA 3FUIA 2VJ8A 2C5ZA 2JCVA 4K5PA 4MKTA 2A7OA 3AUAA 3B37A 3FU0A 4OOEA 4R5TA 3CZGA 1JGIA 3IIEA 1Q0QA 2WZGA 3A14A 3CIAA 3JT1A 1OR7A 4K5LA 3ZI0A 1T1RA 2QVWA 1ZS2A 3CHOA 4PU2A 4OOFA 4Y67A 2Y1CA 3QJXA 2JCYA 4Q4EA 3FH8A 4XNDA 3ANMA 2WZFA 3FUNA 4Y6PA 3UCQA 2XPZA 3FTXA 3FTZA 2Y1FA 1T1SA 3UERA 3UEQA 3WQQA 5JC1A 3FH5A 3ZHXA 4QHPA 1MW2A 4MS6A 4CXFA 2EGHA 4FLRA 4ZX4A 3CHQA 2JD0A 4J3BA 4JNDA 5AENA 1G5AA 4LUPA 1X3WA 1SQMA 2HPOA 1K5HA 3AU9A 4ZQHA 3VVMA 3ZHZA 2VLAA 4RVBA 2JD2A 1SC5A 3B3BA 3ANLA 4QIRA 4XMWA 4ZW7A 1S46A 1H3LA 1MW0A 2PGGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2C5Z A;  2A7O A; 
#chains in the Genus database with same CATH topology
 4XNA A;  4XN5 A;  3B2X A;  4KP7 A;  3CZE A;  2MAO A;  3FU6 A;  2Y1D A;  4FLQ A;  4K5N A;  4PW4 A;  3AU8 A;  3PUU A;  4Y6R A;  4XO4 A;  4QUO A;  4X2U A;  2XPY A;  3FUF A;  2RJI A;  5HNH A;  4L2L A;  1H19 A;  4ZX5 A;  4GAE A;  3EBG A;  3CZK A;  1R0K A;  4XN4 A;  3T8V A;  3CHS A;  5DLL A;  4R5V A;  4A03 A;  2GTQ A;  4K5M A;  5EV7 A;  3JSZ A;  3FUL A;  4Y6S A;  3FTV A;  4XN8 A;  1MW3 A;  2XQ0 A;  3HW2 A;  2R70 A;  3B2P A;  2Y1G A;  5JBI A;  3RC8 A;  2Y1E A;  4XN2 A;  5JO0 A;  2MAP A;  1MW1 A;  5JNL A;  3B7S A;  3RC3 A;  1X3Z A;  2JD1 A;  4FCA A;  3WQR A;  3CHP A;  5HLT A;  1MVY A;  2PL5 A;  2DQM A;  3FUH A;  5JMW A;  1RP3 A;  3Q43 A;  1ONN A;  2JCX A;  5DYF A;  4XMZ A;  2JV7 A;  4ZQF A;  2HPT A;  1GW6 A;  4ZW5 A;  3A06 A;  4XNB A;  4AYS A;  3EBH A;  4ZW8 A;  3ZHY A;  2R72 A;  4ZW6 A;  3FH7 A;  1Q0L A;  2O7G A;  3CZL A;  4XMU A;  5FWQ A;  3T0Y A;  1JVS A;  3CHR A;  5JAZ A;  3VVL A;  3FU3 A;  3FUM A;  4R5X A;  1ONP A;  5BPP A;  3R0I A;  2FFL A;  3FHE A;  3U9W A;  3FUD A;  5DUL A;  4FLO A;  4AIC A;  4QPE A;  4XN9 A;  3B7T A;  4XO3 A;  3B34 A;  1JG9 A;  3KED A;  4AR1 A;  1Q0H A;  4RCV A;  4K5O A;  4RSY A;  3FTY A;  4ZX3 A;  4PVB A;  1ONO A;  1SG7 A;  2C82 A;  3FU5 A;  4XMT A;  3Q44 A;  4AR9 A;  4BKX A;  4XO5 A;  3ANN A;  4ARF A;  2ZXG A;  3FTW A;  3RAS A;  4QME A;  3B7U X;  2R59 A;  4DPR A;  2WPG A;  4ZX6 A;  4GAA A;  4ZQE A;  4XMX A;  3FUJ A;  3FUK A;  1R0L A;  4ZW3 A;  4XN7 A;  5JMP A;  4XMV A;  3B7R L;  3FUE A;  4ZN6 A;  3FTU A;  4ZQT A;  4NQW A;  2DQ6 A;  2B61 A;  4XN1 A;  4ZQG A;  4FLS A;  5HNF A;  4AR8 A;  4R7L A;  3EBI A;  2PUS A;  1HS6 A;  3WQS B;  2QJ1 A;  3FTS A;  4Q4I A;  3FUI A;  2VJ8 A;  2C5Z A;  2JCV A;  4K5P A;  4MKT A;  2A7O A;  3AUA A;  3B37 A;  3FU0 A;  4OOE A;  4R5T A;  3CZG A;  1JGI A;  3IIE A;  1Q0Q A;  2WZG A;  3A14 A;  3CIA A;  3JT1 A;  1OR7 A;  4K5L A;  3ZI0 A;  1T1R A;  2QVW A;  1ZS2 A;  3CHO A;  4PU2 A;  4OOF A;  4Y67 A;  2Y1C A;  3QJX A;  2JCY A;  4Q4E A;  3FH8 A;  4XND A;  3ANM A;  2WZF A;  3FUN A;  4Y6P A;  3UCQ A;  2XPZ A;  3FTX A;  3CXB A;  2Y1F A;  1T1S A;  3FTZ A;  3UER A;  3UEQ A;  3WQQ A;  5JC1 A;  3FH5 A;  3ZHX A;  4QHP A;  1MW2 A;  4MS6 A;  4CXF A;  2EGH A;  4FLR A;  4ZX4 A;  3CHQ A;  2JD0 A;  4J3B A;  4JND A;  5AEN A;  1G5A A;  4LUP A;  1X3W A;  1SQM A;  2HPO A;  1K5H A;  3AU9 A;  4ZQH A;  3VVM A;  3ZHZ A;  2VLA A;  4RVB A;  2JD2 A;  1SC5 A;  3B3B A;  3ANL A;  4QIR A;  4XMW A;  4ZW7 A;  1S46 A;  1H3L A;  1MW0 A;  2PGG A; 
#chains in the Genus database with same CATH homology
 4XNA A;  4XN5 A;  3B2X A;  4KP7 A;  3CZE A;  2MAO A;  3FU6 A;  2Y1D A;  4FLQ A;  4K5N A;  4PW4 A;  3AU8 A;  3PUU A;  4Y6R A;  4XO4 A;  4QUO A;  4X2U A;  2XPY A;  3FUF A;  2RJI A;  5HNH A;  4L2L A;  1H19 A;  4ZX5 A;  4GAE A;  3EBG A;  3CZK A;  1R0K A;  4XN4 A;  3T8V A;  3CHS A;  5DLL A;  4R5V A;  4A03 A;  2GTQ A;  4K5M A;  5EV7 A;  3JSZ A;  3FUL A;  4Y6S A;  3FTV A;  4XN8 A;  1MW3 A;  2XQ0 A;  2R70 A;  3B2P A;  2Y1G A;  5JBI A;  3RC8 A;  2Y1E A;  4XN2 A;  5JO0 A;  2MAP A;  1MW1 A;  5JNL A;  3B7S A;  3RC3 A;  1X3Z A;  2JD1 A;  4FCA A;  3WQR A;  3CHP A;  5HLT A;  1MVY A;  2PL5 A;  2DQM A;  3FUH A;  5JMW A;  1RP3 A;  3Q43 A;  1ONN A;  2JCX A;  5DYF A;  4XMZ A;  2JV7 A;  4ZQF A;  2HPT A;  1GW6 A;  4ZW5 A;  3A06 A;  4XNB A;  4AYS A;  3EBH A;  4ZW8 A;  3ZHY A;  2R72 A;  4ZW6 A;  3FH7 A;  1Q0L A;  2O7G A;  3CZL A;  4XMU A;  5FWQ A;  3T0Y A;  1JVS A;  3CHR A;  5JAZ A;  3VVL A;  3FU3 A;  3FUM A;  4R5X A;  1ONP A;  5BPP A;  3R0I A;  2FFL A;  3FHE A;  3U9W A;  3FUD A;  5DUL A;  4FLO A;  4AIC A;  4QPE A;  4XN9 A;  3B7T A;  4XO3 A;  3B34 A;  1JG9 A;  3KED A;  4AR1 A;  1Q0H A;  4RCV A;  4K5O A;  4RSY A;  3FTY A;  4ZX3 A;  4PVB A;  1ONO A;  1SG7 A;  2C82 A;  3FU5 A;  4XMT A;  3Q44 A;  4AR9 A;  4BKX A;  4XO5 A;  3ANN A;  4ARF A;  2ZXG A;  3FTW A;  3RAS A;  4QME A;  3B7U X;  2R59 A;  4DPR A;  2WPG A;  4ZX6 A;  4GAA A;  4ZQE A;  4XMX A;  3FUJ A;  3FUK A;  1R0L A;  4ZW3 A;  4XN7 A;  5JMP A;  4XMV A;  3B7R L;  3FUE A;  4ZN6 A;  3FTU A;  4ZQT A;  4NQW A;  2DQ6 A;  2B61 A;  4XN1 A;  4ZQG A;  4FLS A;  5HNF A;  4AR8 A;  4R7L A;  3EBI A;  2PUS A;  1HS6 A;  3WQS B;  2QJ1 A;  3FTS A;  4Q4I A;  3FUI A;  2VJ8 A;  2C5Z A;  2JCV A;  4K5P A;  4MKT A;  2A7O A;  3AUA A;  3B37 A;  3FU0 A;  4OOE A;  4R5T A;  3CZG A;  1JGI A;  3IIE A;  1Q0Q A;  2WZG A;  3A14 A;  3CIA A;  3JT1 A;  1OR7 A;  4K5L A;  3ZI0 A;  1T1R A;  2QVW A;  1ZS2 A;  3CHO A;  4PU2 A;  4OOF A;  4Y67 A;  2Y1C A;  3QJX A;  2JCY A;  4Q4E A;  3FH8 A;  4XND A;  3ANM A;  2WZF A;  3FUN A;  4Y6P A;  3UCQ A;  2XPZ A;  3FTX A;  3FTZ A;  2Y1F A;  1T1S A;  3UER A;  3UEQ A;  3WQQ A;  5JC1 A;  3FH5 A;  3ZHX A;  4QHP A;  1MW2 A;  4MS6 A;  4CXF A;  2EGH A;  4FLR A;  4ZX4 A;  3CHQ A;  2JD0 A;  4J3B A;  4JND A;  5AEN A;  1G5A A;  4LUP A;  1X3W A;  1SQM A;  2HPO A;  1K5H A;  3AU9 A;  4ZQH A;  3VVM A;  3ZHZ A;  2VLA A;  4RVB A;  2JD2 A;  1SC5 A;  3B3B A;  3ANL A;  4QIR A;  4XMW A;  4ZW7 A;  1S46 A;  1H3L A;  1MW0 A;  2PGG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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