2A7OA

Solution structure of the hset2/hypb sri domain
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
100
structure length
100
Chain Sequence
TSSELAKKSKEVFRKEMSQFIVQCLNPYRKPDCKVGRITTTEDFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQKFGAVYKPKEDT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the Set2 Rpb1 interacting domain of human Set2 and its interaction with the hyperphosphorylated C-terminal domain of Rpb1
pubmed doi rcsb
molecule tags Transcription
source organism Homo sapiens
molecule keywords Huntingtin interacting protein B
total genus 38
structure length 100
sequence length 100
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2005-07-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08236 SRI SRI (Set2 Rpb1 interacting) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1740.100 Mainly Alpha Orthogonal Bundle Rna Polymerase Sigma Factor; Chain: A Rna Polymerase Sigma Factor; Chain: A 2a7oA00
2C5ZA 2A7OA
chains in the Genus database with same CATH superfamily
3A06A 3FUHA 4RCVA 2QJ1A 4XNBA 5EV7A 3R0IA 4ZX5A 4DPRA 2MAOA 4ZN6A 1R0LA 2B61A 1OR7A 2JV7A 4K5NA 3FTUA 4Y67A 4Y6PA 1T1RA 2JCVA 4XMUA 4L2LA 3RASA 4ZW5A 2R72A 3Q43A 5JC1A 2VJ8A 3B7TA 4FCAA 4XO4A 4ZX6A 5JAZA 3FU0A 5DULA 2QVWA 3B7RL 3CZKA 4ZQHA 2WZFA 5JO0A 1H3LA 1HS6A 4NQWA 4GAAA 2C5ZA 2HPTA 2PUSA 3B7UX 3FH8A 4QIRA 1H19A 4XNAA 3RC8A 3AU8A 4Q4EA 4RSYA 3QJXA 3FTVA 2Y1EA 4OOFA 4PW4A 4XN2A 4AICA 4ZX3A 4FLOA 4XO5A 2Y1CA 3CZGA 3ANMA 5JNLA 4XN1A 3Q44A 4GAEA 2R70A 5JMPA 3B3BA 3UERA 2C82A 3ZHYA 1JGIA 3EBGA 1MW1A 1Q0HA 5DYFA 4XMZA 1ONOA 3ANLA 5FWQA 1Q0QA 3EBIA 4XO3A 3WQQA 3FUDA 3FUMA 3B2PA 1ZS2A 1JG9A 2R59A 3FUNA 1X3ZA 1S46A 4FLRA 4K5LA 4K5MA 4X2UA 1MVYA 5BPPA 5HLTA 2HPOA 2PL5A 2A7OA 4R5XA 3ZHXA 3FTWA 4XNDA 3FU3A 3B34A 1JVSA 4Y6RA 5HNHA 4XN9A 2DQ6A 4ZQTA 3ZHZA 1R0KA 3B37A 4XMWA 3RC3A 1ONNA 2JD2A 3FTSA 4MKTA 3CZLA 3FTXA 1T1SA 1SG7A 3CHOA 4K5PA 3B7SA 2XPZA 2Y1FA 4AR9A 4XN5A 5AENA 2VLAA 2MAPA 2JD0A 3KEDA 4RVBA 2Y1GA 2O7GA 4LUPA 3AUAA 2EGHA 4ZW7A 3FUKA 4R7LA 1MW2A 4OOEA 1K5HA 4ZX4A 3CXBA 4PU2A 4JNDA 3B2XA 4XMTA 2JD1A 3FU5A 4R5TA 3FH5A 4PVBA 4XMXA 4XN7A 4QUOA 4QHPA 3CHQA 3WQRA 4XN4A 3WQSB 2JCXA 1RP3A 4MS6A 1MW0A 4FLSA 3CHPA 4FLQA 3FH7A 3A14A 1GW6A 4KP7A 4Q4IA 3FUFA 3AU9A 1SC5A 4ZQEA 5HNFA 2ZXGA 4A03A 4ARFA 3JT1A 3UCQA 2JCYA 3JSZA 3CHSA 3T0YA 3FTZA 5JMWA 4ZQGA 3CZEA 2DQMA 3ANNA 3CIAA 4AR8A 3VVLA 3EBHA 3PUUA 3T8VA 4ZW8A 4XN8A 3FU6A 2Y1DA 2FFLA 2WPGA 3FUIA 2GTQA 4CXFA 3FTYA 3CHRA 4K5OA 4QMEA 2PGGA 3VVMA 4J3BA 4QPEA 3ZI0A 1G5AA 4R5VA 3UEQA 5JBIA 4AR1A 4ZQFA 1MW3A 4ZW3A 3FHEA 3FULA 2RJIA 4XMVA 4BKXA 2XQ0A 1ONPA 4ZW6A 4Y6SA 1X3WA 2XPYA 3U9WA 1SQMA 1Q0LA 3IIEA 4AYSA 5DLLA 2WZGA 3FUJA 3FUEA 3HW2A
chains in the Genus database with same CATH topology
3A06A 3FUHA 4RCVA 2QJ1A 4XNBA 5EV7A 3R0IA 4ZX5A 4DPRA 2MAOA 4ZN6A 1R0LA 2B61A 1OR7A 2JV7A 4K5NA 3FTUA 4Y67A 4Y6PA 1T1RA 2JCVA 4XMUA 4L2LA 3RASA 4ZW5A 2R72A 3Q43A 5JC1A 2VJ8A 3B7TA 4FCAA 4XO4A 4ZX6A 5JAZA 3FU0A 5DULA 2QVWA 3B7RL 3CZKA 4ZQHA 2WZFA 5JO0A 1H3LA 1HS6A 4NQWA 4GAAA 2C5ZA 2HPTA 2PUSA 3B7UX 3FH8A 4QIRA 1H19A 4XNAA 3RC8A 3AU8A 4Q4EA 4RSYA 3QJXA 3FTVA 2Y1EA 4OOFA 4PW4A 4XN2A 4AICA 4ZX3A 4FLOA 4XO5A 2Y1CA 3CZGA 3ANMA 5JNLA 4XN1A 3Q44A 4GAEA 2R70A 5JMPA 3B3BA 3UERA 2C82A 3ZHYA 1JGIA 3EBGA 1MW1A 1Q0HA 5DYFA 4XMZA 1ONOA 3ANLA 5FWQA 1Q0QA 3EBIA 4XO3A 3WQQA 3FUDA 3FUMA 3B2PA 1ZS2A 1JG9A 2R59A 3FUNA 1X3ZA 1S46A 4FLRA 4K5LA 4K5MA 4X2UA 1MVYA 5BPPA 5HLTA 2HPOA 2PL5A 2A7OA 4R5XA 3ZHXA 3FTWA 4XNDA 3FU3A 3B34A 1JVSA 4Y6RA 5HNHA 4XN9A 2DQ6A 4ZQTA 3ZHZA 1R0KA 3B37A 4XMWA 3RC3A 1ONNA 2JD2A 3FTSA 4MKTA 3CZLA 3FTXA 1T1SA 1SG7A 3CHOA 4K5PA 3B7SA 2XPZA 2Y1FA 4AR9A 4XN5A 5AENA 2VLAA 2MAPA 2JD0A 3KEDA 4RVBA 2Y1GA 2O7GA 4LUPA 3AUAA 2EGHA 4ZW7A 3FUKA 4R7LA 1MW2A 4OOEA 1K5HA 4ZX4A 4PU2A 4JNDA 3B2XA 4XMTA 2JD1A 3FU5A 4R5TA 3FH5A 4PVBA 4XMXA 4XN7A 4QUOA 4QHPA 3CHQA 3WQRA 4XN4A 3WQSB 2JCXA 1RP3A 4MS6A 1MW0A 4FLSA 3CHPA 4FLQA 3FH7A 3A14A 1GW6A 4KP7A 4Q4IA 3FUFA 3AU9A 1SC5A 4ZQEA 5HNFA 2ZXGA 4A03A 4ARFA 3JT1A 3UCQA 2JCYA 3JSZA 3CHSA 3T0YA 3FTZA 5JMWA 4ZQGA 3CZEA 2DQMA 3ANNA 3CIAA 4AR8A 3VVLA 3EBHA 3PUUA 3T8VA 4ZW8A 4XN8A 3FU6A 2Y1DA 2FFLA 2WPGA 3FUIA 2GTQA 4CXFA 3FTYA 3CHRA 4K5OA 4QMEA 2PGGA 3VVMA 4J3BA 4QPEA 3ZI0A 1G5AA 4R5VA 3UEQA 5JBIA 4AR1A 4ZQFA 1MW3A 4ZW3A 3FHEA 3FULA 2RJIA 4XMVA 4BKXA 2XQ0A 1ONPA 4ZW6A 4Y6SA 1X3WA 2XPYA 3U9WA 1SQMA 1Q0LA 3IIEA 4AYSA 5DLLA 2WZGA 3FUJA 3FUEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2C5Z A;  2A7O A; 
#chains in the Genus database with same CATH topology
 3A06 A;  3FUH A;  4RCV A;  2QJ1 A;  4XNB A;  5EV7 A;  3R0I A;  4ZX5 A;  4DPR A;  2MAO A;  4ZN6 A;  1R0L A;  2B61 A;  1OR7 A;  2JV7 A;  4K5N A;  3FTU A;  4Y67 A;  4Y6P A;  1T1R A;  2JCV A;  4XMU A;  4L2L A;  3RAS A;  4ZW5 A;  2R72 A;  3Q43 A;  5JC1 A;  2VJ8 A;  3B7T A;  4FCA A;  4XO4 A;  4ZX6 A;  5JAZ A;  3FU0 A;  5DUL A;  2QVW A;  3B7R L;  3CZK A;  4ZQH A;  2WZF A;  5JO0 A;  1H3L A;  1HS6 A;  4NQW A;  4GAA A;  2C5Z A;  2HPT A;  2PUS A;  3B7U X;  3FH8 A;  4QIR A;  1H19 A;  4XNA A;  3RC8 A;  3AU8 A;  4Q4E A;  4RSY A;  3QJX A;  3FTV A;  2Y1E A;  4OOF A;  4PW4 A;  4XN2 A;  4AIC A;  4ZX3 A;  4FLO A;  4XO5 A;  2Y1C A;  3CZG A;  3ANM A;  5JNL A;  4XN1 A;  3Q44 A;  4GAE A;  2R70 A;  5JMP A;  3B3B A;  3UER A;  2C82 A;  3ZHY A;  1JGI A;  3EBG A;  1MW1 A;  1Q0H A;  5DYF A;  4XMZ A;  1ONO A;  3ANL A;  5FWQ A;  1Q0Q A;  3EBI A;  4XO3 A;  3WQQ A;  3FUD A;  3FUM A;  3B2P A;  1ZS2 A;  1JG9 A;  2R59 A;  3FUN A;  1X3Z A;  1S46 A;  4FLR A;  4K5L A;  4K5M A;  4X2U A;  1MVY A;  5BPP A;  5HLT A;  2HPO A;  2PL5 A;  2A7O A;  4R5X A;  3ZHX A;  3FTW A;  4XND A;  3FU3 A;  3B34 A;  1JVS A;  4Y6R A;  5HNH A;  4XN9 A;  2DQ6 A;  4ZQT A;  3ZHZ A;  1R0K A;  3B37 A;  4XMW A;  3RC3 A;  1ONN A;  2JD2 A;  3FTS A;  4MKT A;  3CZL A;  3FTX A;  1T1S A;  1SG7 A;  3CHO A;  4K5P A;  3B7S A;  2XPZ A;  2Y1F A;  4AR9 A;  4XN5 A;  5AEN A;  2VLA A;  2MAP A;  2JD0 A;  3KED A;  4RVB A;  2Y1G A;  2O7G A;  4LUP A;  3AUA A;  2EGH A;  4ZW7 A;  3FUK A;  4R7L A;  1MW2 A;  4OOE A;  1K5H A;  4ZX4 A;  3CXB A;  4PU2 A;  4JND A;  3B2X A;  4XMT A;  2JD1 A;  3FU5 A;  4R5T A;  3FH5 A;  4PVB A;  4XMX A;  4XN7 A;  4QUO A;  4QHP A;  3CHQ A;  3WQR A;  4XN4 A;  3WQS B;  2JCX A;  1RP3 A;  4MS6 A;  1MW0 A;  4FLS A;  3CHP A;  4FLQ A;  3FH7 A;  3A14 A;  1GW6 A;  4KP7 A;  4Q4I A;  3FUF A;  3AU9 A;  1SC5 A;  4ZQE A;  5HNF A;  2ZXG A;  4A03 A;  4ARF A;  3JT1 A;  3UCQ A;  2JCY A;  3JSZ A;  3CHS A;  3T0Y A;  3FTZ A;  5JMW A;  4ZQG A;  3CZE A;  2DQM A;  3ANN A;  3CIA A;  4AR8 A;  3VVL A;  3EBH A;  3PUU A;  3T8V A;  4ZW8 A;  4XN8 A;  3FU6 A;  2Y1D A;  2FFL A;  2WPG A;  3FUI A;  2GTQ A;  4CXF A;  3FTY A;  3CHR A;  4K5O A;  4QME A;  2PGG A;  3VVM A;  4J3B A;  4QPE A;  3ZI0 A;  1G5A A;  4R5V A;  3UEQ A;  5JBI A;  4AR1 A;  4ZQF A;  1MW3 A;  4ZW3 A;  3FHE A;  3FUL A;  2RJI A;  4XMV A;  4BKX A;  2XQ0 A;  1ONP A;  4ZW6 A;  4Y6S A;  1X3W A;  2XPY A;  3U9W A;  1SQM A;  1Q0L A;  3IIE A;  4AYS A;  5DLL A;  2WZG A;  3FUJ A;  3FUE A;  3HW2 A; 
#chains in the Genus database with same CATH homology
 3A06 A;  3FUH A;  4RCV A;  2QJ1 A;  4XNB A;  5EV7 A;  3R0I A;  4ZX5 A;  4DPR A;  2MAO A;  4ZN6 A;  1R0L A;  2B61 A;  1OR7 A;  2JV7 A;  4K5N A;  3FTU A;  4Y67 A;  4Y6P A;  1T1R A;  2JCV A;  4XMU A;  4L2L A;  3RAS A;  4ZW5 A;  2R72 A;  3Q43 A;  5JC1 A;  2VJ8 A;  3B7T A;  4FCA A;  4XO4 A;  4ZX6 A;  5JAZ A;  3FU0 A;  5DUL A;  2QVW A;  3B7R L;  3CZK A;  4ZQH A;  2WZF A;  5JO0 A;  1H3L A;  1HS6 A;  4NQW A;  4GAA A;  2C5Z A;  2HPT A;  2PUS A;  3B7U X;  3FH8 A;  4QIR A;  1H19 A;  4XNA A;  3RC8 A;  3AU8 A;  4Q4E A;  4RSY A;  3QJX A;  3FTV A;  2Y1E A;  4OOF A;  4PW4 A;  4XN2 A;  4AIC A;  4ZX3 A;  4FLO A;  4XO5 A;  2Y1C A;  3CZG A;  3ANM A;  5JNL A;  4XN1 A;  3Q44 A;  4GAE A;  2R70 A;  5JMP A;  3B3B A;  3UER A;  2C82 A;  3ZHY A;  1JGI A;  3EBG A;  1MW1 A;  1Q0H A;  5DYF A;  4XMZ A;  1ONO A;  3ANL A;  5FWQ A;  1Q0Q A;  3EBI A;  4XO3 A;  3WQQ A;  3FUD A;  3FUM A;  3B2P A;  1ZS2 A;  1JG9 A;  2R59 A;  3FUN A;  1X3Z A;  1S46 A;  4FLR A;  4K5L A;  4K5M A;  4X2U A;  1MVY A;  5BPP A;  5HLT A;  2HPO A;  2PL5 A;  2A7O A;  4R5X A;  3ZHX A;  3FTW A;  4XND A;  3FU3 A;  3B34 A;  1JVS A;  4Y6R A;  5HNH A;  4XN9 A;  2DQ6 A;  4ZQT A;  3ZHZ A;  1R0K A;  3B37 A;  4XMW A;  3RC3 A;  1ONN A;  2JD2 A;  3FTS A;  4MKT A;  3CZL A;  3FTX A;  1T1S A;  1SG7 A;  3CHO A;  4K5P A;  3B7S A;  2XPZ A;  2Y1F A;  4AR9 A;  4XN5 A;  5AEN A;  2VLA A;  2MAP A;  2JD0 A;  3KED A;  4RVB A;  2Y1G A;  2O7G A;  4LUP A;  3AUA A;  2EGH A;  4ZW7 A;  3FUK A;  4R7L A;  1MW2 A;  4OOE A;  1K5H A;  4ZX4 A;  4PU2 A;  4JND A;  3B2X A;  4XMT A;  2JD1 A;  3FU5 A;  4R5T A;  3FH5 A;  4PVB A;  4XMX A;  4XN7 A;  4QUO A;  4QHP A;  3CHQ A;  3WQR A;  4XN4 A;  3WQS B;  2JCX A;  1RP3 A;  4MS6 A;  1MW0 A;  4FLS A;  3CHP A;  4FLQ A;  3FH7 A;  3A14 A;  1GW6 A;  4KP7 A;  4Q4I A;  3FUF A;  3AU9 A;  1SC5 A;  4ZQE A;  5HNF A;  2ZXG A;  4A03 A;  4ARF A;  3JT1 A;  3UCQ A;  2JCY A;  3JSZ A;  3CHS A;  3T0Y A;  3FTZ A;  5JMW A;  4ZQG A;  3CZE A;  2DQM A;  3ANN A;  3CIA A;  4AR8 A;  3VVL A;  3EBH A;  3PUU A;  3T8V A;  4ZW8 A;  4XN8 A;  3FU6 A;  2Y1D A;  2FFL A;  2WPG A;  3FUI A;  2GTQ A;  4CXF A;  3FTY A;  3CHR A;  4K5O A;  4QME A;  2PGG A;  3VVM A;  4J3B A;  4QPE A;  3ZI0 A;  1G5A A;  4R5V A;  3UEQ A;  5JBI A;  4AR1 A;  4ZQF A;  1MW3 A;  4ZW3 A;  3FHE A;  3FUL A;  2RJI A;  4XMV A;  4BKX A;  2XQ0 A;  1ONP A;  4ZW6 A;  4Y6S A;  1X3W A;  2XPY A;  3U9W A;  1SQM A;  1Q0L A;  3IIE A;  4AYS A;  5DLL A;  2WZG A;  3FUJ A;  3FUE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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