2AVTA

Crystal structure of the beta subunit from dna polymerase of streptococcus pyogenes
Total Genus 92
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
92
sequence length
377
structure length
372
Chain Sequence
MIQFSINRTLFIHALNTTKRAISTKNAIPILSSIKIEVTSTGVTLTGSNGQISIENTIPVGLLITSPGAILLEASFFINIISSLPDISINVKEIEQHQVVLTSGKSEITLKGKDVDQYPRLQEVSTENPLILKTKLLKSIIAETAFAASLQESRPILTGVHIVLSNHKDFKAVATDSHRMSQRLITLDNTSADFMVVLPSKSLREFSAVFTDDIETVEVFFSPSQILFRSEHISFYTRLLEGNYPDTDRLLMTEFETEVVFNTQSLRHAMERAFLISNATQNGTVKLEITQNHISAHVNSPEVGKVNEDLDIVSQSGSDLTISFNPTYLIESLKAIKSETVKIHFLSPVRPFTLTPGDEEESFIQLITPVRT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of a DNA polymerase sliding clamp from a Gram-positive bacterium.
pubmed doi rcsb
molecule tags Transferase
source organism Streptococcus pyogenes
molecule keywords DNA polymerase III beta subunit
total genus 92
structure length 372
sequence length 377
chains with identical sequence B
ec nomenclature ec 2.7.7.-:
pdb deposition date 2005-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00712 DNA_pol3_beta DNA polymerase III beta subunit, N-terminal domain
A PF02767 DNA_pol3_beta_2 DNA polymerase III beta subunit, central domain
A PF02768 DNA_pol3_beta_3 DNA polymerase III beta subunit, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 2avtA01
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 2avtA02
3GPMA 1W60A 2IO4B 3V62B 1T6LA 5IY4A 3K4XA 1U7BA 4N97A 3BEPA 3GPNA 3FDSD 2IX2C 3LX2A 2ZVMA 5AH2A 3QSBB 4HK1A 3P16A 1YYPA 2IZOB 4ZTDA 1VPKA 2IX2A 3A2FB 1SXJF 1PLQA 5AGUA 4MJPA 4N96A 1U76A 2HIKC 2ZVLA 3G65A 4S3IA 3GGRB 1PLRA 4YHRA 3D1EA 3PWEA 3U5ZF 3P91A 1IZ5A 5B7OA 3V61B 4PNUA 2HIIA 3VKXA 1RWZA 2HIKA 3FDSC 2AVTA 4N99A 5IWDA 1OK7A 4K74A 5E0VA 4N98A 1B8HA 4OVFA 4K3LA 1MMIA 3D1GA 3L10A 5FVEA 1RXMA 4K3KA 3A1JB 2POLA 1GE8A 2NTIC 4PNWA 1IZ4A 5HACA 1AXCA 4TR8A 3WGWA 4N94A 4N95A 3HSLX 2ZVWA 5AH4A 4K3PA 3AIXA 3IFVA 3V60B 4MJRA 2NTIA 1UNNA 2AWAA 3L0WA 4TR7A 4L6PA 3G65B 1UD9A 3T0PA 4TRTA 1CZDA 5H0TA 3AIZC 4PNVA 4TR6A 3U60F 3D1FA 1B77A 3P83A 3F1WA 3Q4KA 4K3SA 3GGRC 4OVHA 3P87A 2HIIB 2ZVVA 4K3QA 3Q4LA 3Q4JA 5AUJA 4D2GA 1ISQA 1UL1A 1VYMA 5A6DA 3LX1A 4CS5A 5CFKA 3U61F 3GGRA 4MJQA 2IO4A 2XURA 4RKIA 2ZVKA 3L0XA 3I2MX 5JNED 2IX2B 3A1JC 4K3RA 2IZOC 4OVGA 3AIXB 3PGEB 5IXAA 3TBLA 1JQLA 2NTIB 4TSZA 2Z0LA 5AGVA 2IJXA 1VYJA 4N9AA 3QSBA 3A1JA 1JQJA 3F1VA 3RB9A 1RXZA 3G65C 2HIKB 2OD8A 3AIZA 4L60A 5FRQA 5E0UA 5DA7A 4K3OA 3HI8A 4K3MA 2HIIC 1DMLA 4RJFA 5DAIA 5E0TA
chains in the Genus database with same CATH superfamily
3GPMA 1W60A 2IO4B 3V62B 1T6LA 5IY4A 3K4XA 1U7BA 4N97A 3L0WB 3BEPA 3GPNA 3FDSD 2IX2C 3LX2A 2ZVMA 5AH2A 3QSBB 4HK1A 3P16A 1YYPA 2IZOB 4ZTDA 1VPKA 2IX2A 3A2FB 1SXJF 1PLQA 5AGUA 4MJPA 3PGEA 4N96A 1U76A 2HIKC 2ZVLA 3G65A 4S3IA 3GGRB 1PLRA 4YHRA 3D1EA 3PWEA 3U5ZF 3L0XB 1IZ5A 3P91A 5B7OA 3V61B 4PNUA 2HIIA 3VKXA 1RWZA 2HIKA 3FDSC 2AVTA 4N99A 5IWDA 1OK7A 4K74A 5E0VA 4N98A 1B8HA 4OVFA 4K3LA 1MMIA 3D1GA 3L10A 5FVEA 1RXMA 4K3KA 3A1JB 2POLA 1GE8A 2NTIC 4PNWA 1IZ4A 5HACA 1AXCA 4TR8A 3WGWA 4N94A 4N95A 3HSLX 2ZVWA 5AH4A 4K3PA 3AIXA 3IFVA 3V60B 4MJRA 2NTIA 1UNNA 2AWAA 3L0WA 4TR7A 4L6PA 3G65B 1UD9A 3T0PA 4TRTA 1CZDA 5H0TA 3AIZC 4PNVA 4TR6A 3U60F 3D1FA 1B77A 3P83A 3F1WA 3Q4KA 4K3SA 3GGRC 4OVHA 3P87A 2HIIB 2ZVVA 4K3QA 3Q4LA 3Q4JA 5AUJA 4D2GA 1ISQA 1UL1A 1VYMA 5A6DA 3LX1A 4CS5A 5CFKA 3U61F 3GGRA 4MJQA 2IO4A 2XURA 4RKIA 2ZVKA 3L0XA 3I2MX 5JNED 2IX2B 3A1JC 4K3RA 2IZOC 4OVGA 3AIXB 3PGEB 5IXAA 3TBLA 1JQLA 2NTIB 4TSZA 2Z0LA 5AGVA 2IJXA 1VYJA 4N9AA 3QSBA 3A1JA 1JQJA 3F1VA 3RB9A 1RXZA 3G65C 2HIKB 2OD8A 3AIZA 4L60A 5FRQA 5E0UA 5DA7A 4K3OA 3HI8A 4K3MA 3L10B 2HIIC 1DMLA 4RJFA 5DAIA 5E0TA
chains in the Genus database with same CATH topology
3GPMA 1W60A 2IO4B 3V62B 1T6LA 5IY4A 3K4XA 1U7BA 4N97A 3BEPA 3GPNA 3FDSD 2IX2C 3LX2A 2ZVMA 5AH2A 3QSBB 4HK1A 3P16A 1YYPA 2IZOB 4ZTDA 1VPKA 2IX2A 3A2FB 1SXJF 1PLQA 5AGUA 4MJPA 4N96A 1U76A 2HIKC 2ZVLA 3G65A 4S3IA 3GGRB 1PLRA 4YHRA 3D1EA 3PWEA 3U5ZF 3P91A 1IZ5A 5B7OA 3V61B 4PNUA 2HIIA 3VKXA 1RWZA 2HIKA 3FDSC 2AVTA 4N99A 5IWDA 1OK7A 4K74A 5E0VA 4N98A 1B8HA 4OVFA 4K3LA 1MMIA 3D1GA 3L10A 5FVEA 1RXMA 4K3KA 3A1JB 2POLA 1GE8A 2NTIC 4PNWA 1IZ4A 5HACA 1AXCA 4TR8A 3WGWA 4N94A 4N95A 3HSLX 2ZVWA 5AH4A 4K3PA 3AIXA 3IFVA 3V60B 4MJRA 2NTIA 1UNNA 2AWAA 3L0WA 4TR7A 4L6PA 3G65B 1UD9A 3T0PA 4TRTA 1CZDA 5H0TA 3AIZC 4PNVA 4TR6A 3U60F 3D1FA 1B77A 3P83A 3F1WA 3Q4KA 4K3SA 3GGRC 4OVHA 3P87A 2HIIB 2ZVVA 4K3QA 3Q4LA 3Q4JA 5AUJA 4D2GA 1ISQA 1UL1A 1VYMA 5A6DA 3LX1A 4CS5A 5CFKA 3U61F 3GGRA 4MJQA 2IO4A 2XURA 4RKIA 2ZVKA 3L0XA 3I2MX 5JNED 2IX2B 3A1JC 4K3RA 2IZOC 4OVGA 3AIXB 3PGEB 5IXAA 3TBLA 1JQLA 2NTIB 4TSZA 2Z0LA 5AGVA 2IJXA 1VYJA 4N9AA 3QSBA 3A1JA 1JQJA 3F1VA 3RB9A 1RXZA 3G65C 2HIKB 2OD8A 3AIZA 4L60A 5FRQA 5E0UA 5DA7A 4K3OA 3HI8A 4K3MA 2HIIC 1DMLA 4RJFA 5DAIA 5E0TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GPM A;  1W60 A;  2IO4 B;  3V62 B;  1T6L A;  5IY4 A;  3K4X A;  1U7B A;  4N97 A;  3BEP A;  3GPN A;  3FDS D;  2IX2 C;  3LX2 A;  2ZVM A;  5AH2 A;  3QSB B;  4HK1 A;  3P16 A;  1YYP A;  2IZO B;  4ZTD A;  1VPK A;  2IX2 A;  3A2F B;  1SXJ F;  1PLQ A;  5AGU A;  4MJP A;  4N96 A;  1U76 A;  2HIK C;  2ZVL A;  3G65 A;  4S3I A;  3GGR B;  1PLR A;  4YHR A;  3D1E A;  3PWE A;  3U5Z F;  3P91 A;  1IZ5 A;  5B7O A;  3V61 B;  4PNU A;  2HII A;  3VKX A;  1RWZ A;  2HIK A;  3FDS C;  2AVT A;  4N99 A;  5IWD A;  1OK7 A;  4K74 A;  5E0V A;  4N98 A;  1B8H A;  4OVF A;  4K3L A;  1MMI A;  3D1G A;  3L10 A;  5FVE A;  1RXM A;  4K3K A;  3A1J B;  2POL A;  1GE8 A;  2NTI C;  4PNW A;  1IZ4 A;  5HAC A;  1AXC A;  4TR8 A;  3WGW A;  4N94 A;  4N95 A;  3HSL X;  2ZVW A;  5AH4 A;  4K3P A;  3AIX A;  3IFV A;  3V60 B;  4MJR A;  2NTI A;  1UNN A;  2AWA A;  3L0W A;  4TR7 A;  4L6P A;  3G65 B;  1UD9 A;  3T0P A;  4TRT A;  1CZD A;  5H0T A;  3AIZ C;  4PNV A;  4TR6 A;  3U60 F;  3D1F A;  1B77 A;  3P83 A;  3F1W A;  3Q4K A;  4K3S A;  3GGR C;  4OVH A;  3P87 A;  2HII B;  2ZVV A;  4K3Q A;  3Q4L A;  3Q4J A;  5AUJ A;  4D2G A;  1ISQ A;  1UL1 A;  1VYM A;  5A6D A;  3LX1 A;  4CS5 A;  5CFK A;  3U61 F;  3GGR A;  4MJQ A;  2IO4 A;  2XUR A;  4RKI A;  2ZVK A;  3L0X A;  3I2M X;  5JNE D;  2IX2 B;  3A1J C;  4K3R A;  2IZO C;  4OVG A;  3AIX B;  3PGE B;  5IXA A;  3TBL A;  1JQL A;  2NTI B;  4TSZ A;  2Z0L A;  5AGV A;  2IJX A;  1VYJ A;  4N9A A;  3QSB A;  3A1J A;  1JQJ A;  3F1V A;  3RB9 A;  1RXZ A;  3G65 C;  2HIK B;  2OD8 A;  3AIZ A;  4L60 A;  5FRQ A;  5E0U A;  5DA7 A;  4K3O A;  3HI8 A;  4K3M A;  2HII C;  1DML A;  4RJF A;  5DAI A;  5E0T A; 
#chains in the Genus database with same CATH topology
 3GPM A;  1W60 A;  2IO4 B;  3V62 B;  1T6L A;  5IY4 A;  3K4X A;  1U7B A;  4N97 A;  3L0W B;  3BEP A;  3GPN A;  3FDS D;  2IX2 C;  3LX2 A;  2ZVM A;  5AH2 A;  3QSB B;  4HK1 A;  3P16 A;  1YYP A;  2IZO B;  4ZTD A;  1VPK A;  2IX2 A;  3A2F B;  1SXJ F;  1PLQ A;  5AGU A;  4MJP A;  3PGE A;  4N96 A;  1U76 A;  2HIK C;  2ZVL A;  3G65 A;  4S3I A;  3GGR B;  1PLR A;  4YHR A;  3D1E A;  3PWE A;  3U5Z F;  3L0X B;  1IZ5 A;  3P91 A;  5B7O A;  3V61 B;  4PNU A;  2HII A;  3VKX A;  1RWZ A;  2HIK A;  3FDS C;  2AVT A;  4N99 A;  5IWD A;  1OK7 A;  4K74 A;  5E0V A;  4N98 A;  1B8H A;  4OVF A;  4K3L A;  1MMI A;  3D1G A;  3L10 A;  5FVE A;  1RXM A;  4K3K A;  3A1J B;  2POL A;  1GE8 A;  2NTI C;  4PNW A;  1IZ4 A;  5HAC A;  1AXC A;  4TR8 A;  3WGW A;  4N94 A;  4N95 A;  3HSL X;  2ZVW A;  5AH4 A;  4K3P A;  3AIX A;  3IFV A;  3V60 B;  4MJR A;  2NTI A;  1UNN A;  2AWA A;  3L0W A;  4TR7 A;  4L6P A;  3G65 B;  1UD9 A;  3T0P A;  4TRT A;  1CZD A;  5H0T A;  3AIZ C;  4PNV A;  4TR6 A;  3U60 F;  3D1F A;  1B77 A;  3P83 A;  3F1W A;  3Q4K A;  4K3S A;  3GGR C;  4OVH A;  3P87 A;  2HII B;  2ZVV A;  4K3Q A;  3Q4L A;  3Q4J A;  5AUJ A;  4D2G A;  1ISQ A;  1UL1 A;  1VYM A;  5A6D A;  3LX1 A;  4CS5 A;  5CFK A;  3U61 F;  3GGR A;  4MJQ A;  2IO4 A;  2XUR A;  4RKI A;  2ZVK A;  3L0X A;  3I2M X;  5JNE D;  2IX2 B;  3A1J C;  4K3R A;  2IZO C;  4OVG A;  3AIX B;  3PGE B;  5IXA A;  3TBL A;  1JQL A;  2NTI B;  4TSZ A;  2Z0L A;  5AGV A;  2IJX A;  1VYJ A;  4N9A A;  3QSB A;  3A1J A;  1JQJ A;  3F1V A;  3RB9 A;  1RXZ A;  3G65 C;  2HIK B;  2OD8 A;  3AIZ A;  4L60 A;  5FRQ A;  5E0U A;  5DA7 A;  4K3O A;  3HI8 A;  4K3M A;  3L10 B;  2HII C;  1DML A;  4RJF A;  5DAI A;  5E0T A; 
#chains in the Genus database with same CATH homology
 3GPM A;  1W60 A;  2IO4 B;  3V62 B;  1T6L A;  5IY4 A;  3K4X A;  1U7B A;  4N97 A;  3BEP A;  3GPN A;  3FDS D;  2IX2 C;  3LX2 A;  2ZVM A;  5AH2 A;  3QSB B;  4HK1 A;  3P16 A;  1YYP A;  2IZO B;  4ZTD A;  1VPK A;  2IX2 A;  3A2F B;  1SXJ F;  1PLQ A;  5AGU A;  4MJP A;  4N96 A;  1U76 A;  2HIK C;  2ZVL A;  3G65 A;  4S3I A;  3GGR B;  1PLR A;  4YHR A;  3D1E A;  3PWE A;  3U5Z F;  3P91 A;  1IZ5 A;  5B7O A;  3V61 B;  4PNU A;  2HII A;  3VKX A;  1RWZ A;  2HIK A;  3FDS C;  2AVT A;  4N99 A;  5IWD A;  1OK7 A;  4K74 A;  5E0V A;  4N98 A;  1B8H A;  4OVF A;  4K3L A;  1MMI A;  3D1G A;  3L10 A;  5FVE A;  1RXM A;  4K3K A;  3A1J B;  2POL A;  1GE8 A;  2NTI C;  4PNW A;  1IZ4 A;  5HAC A;  1AXC A;  4TR8 A;  3WGW A;  4N94 A;  4N95 A;  3HSL X;  2ZVW A;  5AH4 A;  4K3P A;  3AIX A;  3IFV A;  3V60 B;  4MJR A;  2NTI A;  1UNN A;  2AWA A;  3L0W A;  4TR7 A;  4L6P A;  3G65 B;  1UD9 A;  3T0P A;  4TRT A;  1CZD A;  5H0T A;  3AIZ C;  4PNV A;  4TR6 A;  3U60 F;  3D1F A;  1B77 A;  3P83 A;  3F1W A;  3Q4K A;  4K3S A;  3GGR C;  4OVH A;  3P87 A;  2HII B;  2ZVV A;  4K3Q A;  3Q4L A;  3Q4J A;  5AUJ A;  4D2G A;  1ISQ A;  1UL1 A;  1VYM A;  5A6D A;  3LX1 A;  4CS5 A;  5CFK A;  3U61 F;  3GGR A;  4MJQ A;  2IO4 A;  2XUR A;  4RKI A;  2ZVK A;  3L0X A;  3I2M X;  5JNE D;  2IX2 B;  3A1J C;  4K3R A;  2IZO C;  4OVG A;  3AIX B;  3PGE B;  5IXA A;  3TBL A;  1JQL A;  2NTI B;  4TSZ A;  2Z0L A;  5AGV A;  2IJX A;  1VYJ A;  4N9A A;  3QSB A;  3A1J A;  1JQJ A;  3F1V A;  3RB9 A;  1RXZ A;  3G65 C;  2HIK B;  2OD8 A;  3AIZ A;  4L60 A;  5FRQ A;  5E0U A;  5DA7 A;  4K3O A;  3HI8 A;  4K3M A;  2HII C;  1DML A;  4RJF A;  5DAI A;  5E0T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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