2C5ZA

Structure and ctd binding of the set2 sri domain
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
93
structure length
93
Chain Sequence
VSQSQRLEHNWNKFFASFVPNLIKKNPQSKQFDHENIKQCAKDIVKILTTKELKKDSSRAPPDDLTKGKRHKVKEFINSYMDKIILKKKQKKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure and carboxyl-terminal domain (CTD) binding of the Set2 SRI domain that couples histone H3 Lys36 methylation to transcription.
pubmed doi rcsb
molecule tags Transcription
source organism Saccharomyces cerevisiae
molecule keywords SET DOMAIN PROTEIN 2
total genus 35
structure length 93
sequence length 93
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2005-11-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08236 SRI SRI (Set2 Rpb1 interacting) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1740.100 Mainly Alpha Orthogonal Bundle Rna Polymerase Sigma Factor; Chain: A Rna Polymerase Sigma Factor; Chain: A 2c5zA00
2C5ZA 2A7OA
chains in the Genus database with same CATH superfamily
3RC8A 4XO3A 4XN7A 4AICA 3FU5A 3FUMA 4ZQTA 1Q0HA 3T0YA 4AYSA 4PVBA 4K5OA 1GW6A 3WQQA 3ZHXA 4CXFA 3CHRA 1RP3A 2XQ0A 4R7LA 3EBIA 1ONOA 3CHSA 3Q43A 4Y6RA 2R59A 4ZX5A 3FUNA 4FLSA 3CHPA 2C5ZA 4KP7A 4ARFA 2DQMA 4AR8A 5JAZA 5JNLA 4RCVA 4QMEA 3QJXA 4QUOA 4LUPA 1SC5A 4Q4EA 3T8VA 1MW1A 5FWQA 3CZLA 3FTVA 4XN9A 3RASA 5BPPA 1G5AA 2R70A 2HPOA 3CZEA 5HNFA 4J3BA 3CZGA 3FUDA 4FLOA 3FTSA 3FH8A 3JSZA 3Q44A 1MW0A 4XO4A 2MAOA 2QVWA 3HW2A 4XMZA 3B2PA 2DQ6A 3B3BA 4RSYA 1MVYA 5JMPA 3WQSB 1SQMA 1JVSA 5DULA 5JMWA 4FLRA 4XNDA 4GAEA 3FUIA 4QIRA 2R72A 1MW3A 2O7GA 3ZI0A 3CXBA 3FUEA 4XN2A 3R0IA 4K5LA 4ZW7A 1R0LA 4BKXA 4XMTA 3ANLA 3FHEA 2A7OA 1T1RA 2QJ1A 2XPYA 2Y1DA 3EBGA 3FTXA 2B61A 3B7SA 5HNHA 3WQRA 2Y1EA 1X3ZA 3FU3A 3FUHA 4K5NA 1ONNA 2JCXA 3FTUA 4PU2A 4Y6SA 4Y6PA 3AU9A 3B37A 4XN5A 1S46A 4NQWA 4XMVA 2GTQA 1T1SA 3B7RL 4ZW5A 4ZW3A 3B2XA 5JO0A 2VLAA 5DYFA 2WPGA 3ANNA 3B7TA 4GAAA 3UERA 3FU6A 3FUJA 4AR1A 3FTZA 3KEDA 5HLTA 4QPEA 1R0KA 3FU0A 2HPTA 5JC1A 4ZW6A 1H19A 3JT1A 1X3WA 4R5TA 4ZQFA 2PGGA 1HS6A 4DPRA 4ZQGA 3AU8A 4ZN6A 3ZHYA 2JCYA 4FLQA 2XPZA 3FUFA 4XN4A 1ONPA 1SG7A 4L2LA 2MAPA 1ZS2A 2JCVA 3A06A 5AENA 4Y67A 4MKTA 4ZW8A 2FFLA 2WZGA 4XN1A 2EGHA 3ZHZA 4ZQHA 4K5PA 3B34A 2C82A 1MW2A 2PUSA 2JD1A 3IIEA 3PUUA 3CZKA 3RC3A 4R5XA 4RVBA 3FH7A 2JV7A 4XMWA 5EV7A 3FH5A 1JG9A 2JD2A 3EBHA 1JGIA 4MS6A 3CIAA 3UEQA 2WZFA 3VVMA 4A03A 4QHPA 1OR7A 3FULA 3FUKA 4OOEA 4XMUA 3ANMA 5DLLA 2PL5A 3UCQA 2Y1CA 3FTYA 3VVLA 4XNBA 2JD0A 2RJIA 2Y1GA 4JNDA 4Q4IA 4ZX3A 3CHQA 4XO5A 3U9WA 4FCAA 3A14A 4XMXA 4K5MA 1Q0LA 3CHOA 3AUAA 2Y1FA 4ZX6A 2VJ8A 4XNAA 4X2UA 5JBIA 1Q0QA 1K5HA 1H3LA 3FTWA 3B7UX 4PW4A 4XN8A 2ZXGA 4OOFA 4R5VA 4ZX4A 4ZQEA 4AR9A
chains in the Genus database with same CATH topology
3RC8A 4XO3A 4XN7A 4AICA 3FU5A 3FUMA 4ZQTA 1Q0HA 3T0YA 4AYSA 4PVBA 4K5OA 1GW6A 3WQQA 3ZHXA 4CXFA 3CHRA 1RP3A 2XQ0A 4R7LA 3EBIA 1ONOA 3CHSA 3Q43A 4Y6RA 2R59A 4ZX5A 3FUNA 4FLSA 3CHPA 2C5ZA 4KP7A 4ARFA 2DQMA 4AR8A 5JAZA 5JNLA 4RCVA 4QMEA 3QJXA 4QUOA 4LUPA 1SC5A 4Q4EA 3T8VA 1MW1A 5FWQA 3CZLA 3FTVA 4XN9A 3RASA 5BPPA 1G5AA 2R70A 2HPOA 3CZEA 5HNFA 4J3BA 3CZGA 3FUDA 4FLOA 3FTSA 3FH8A 3JSZA 3Q44A 1MW0A 4XO4A 2MAOA 2QVWA 4XMZA 3B2PA 2DQ6A 3B3BA 4RSYA 1MVYA 5JMPA 3WQSB 1SQMA 1JVSA 5DULA 5JMWA 4FLRA 4XNDA 4GAEA 3FUIA 4QIRA 2R72A 1MW3A 2O7GA 3ZI0A 4XN2A 3FUEA 4ZW7A 3R0IA 4K5LA 4BKXA 1R0LA 4XMTA 3ANLA 3FHEA 2A7OA 1T1RA 2QJ1A 2XPYA 2Y1DA 3EBGA 3FTXA 2B61A 3B7SA 5HNHA 3WQRA 2Y1EA 1X3ZA 3FU3A 3FUHA 4K5NA 1ONNA 2JCXA 3FTUA 4PU2A 4Y6SA 4Y6PA 3AU9A 3B37A 4XN5A 1S46A 4NQWA 4XMVA 2GTQA 1T1SA 3B7RL 4ZW5A 4ZW3A 3B2XA 5JO0A 2VLAA 5DYFA 2WPGA 3ANNA 3B7TA 4GAAA 3UERA 3FU6A 3FUJA 4AR1A 3FTZA 3KEDA 5HLTA 4QPEA 1R0KA 3FU0A 2HPTA 5JC1A 4ZW6A 1H19A 3JT1A 1X3WA 4R5TA 4ZQFA 2PGGA 1HS6A 4DPRA 4ZQGA 3AU8A 4ZN6A 3ZHYA 2JCYA 4FLQA 2XPZA 3FUFA 4XN4A 1ONPA 1SG7A 4L2LA 2MAPA 1ZS2A 2JCVA 3A06A 5AENA 4Y67A 4MKTA 4ZW8A 2FFLA 2WZGA 4XN1A 2EGHA 3ZHZA 4ZQHA 4K5PA 3B34A 2C82A 1MW2A 2PUSA 2JD1A 3IIEA 3PUUA 3CZKA 3RC3A 4R5XA 4RVBA 3FH7A 2JV7A 4XMWA 5EV7A 3FH5A 1JG9A 2JD2A 3EBHA 1JGIA 4MS6A 3CIAA 3UEQA 2WZFA 3VVMA 4A03A 4QHPA 1OR7A 3FULA 3FUKA 4OOEA 4XMUA 3ANMA 5DLLA 2PL5A 3UCQA 2Y1CA 3FTYA 3VVLA 4XNBA 2JD0A 2RJIA 2Y1GA 4JNDA 4Q4IA 4ZX3A 3CHQA 4XO5A 3U9WA 4FCAA 3A14A 4XMXA 4K5MA 1Q0LA 3CHOA 3AUAA 2Y1FA 4ZX6A 2VJ8A 4XNAA 4X2UA 5JBIA 1Q0QA 1K5HA 1H3LA 3FTWA 3B7UX 4PW4A 4XN8A 2ZXGA 4OOFA 4R5VA 4ZX4A 4ZQEA 4AR9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2C5Z A;  2A7O A; 
#chains in the Genus database with same CATH topology
 3RC8 A;  4XO3 A;  4XN7 A;  4AIC A;  3FU5 A;  3FUM A;  4ZQT A;  1Q0H A;  3T0Y A;  4AYS A;  4PVB A;  4K5O A;  1GW6 A;  3WQQ A;  3ZHX A;  4CXF A;  3CHR A;  1RP3 A;  2XQ0 A;  4R7L A;  3EBI A;  1ONO A;  3CHS A;  3Q43 A;  4Y6R A;  2R59 A;  4ZX5 A;  3FUN A;  4FLS A;  3CHP A;  2C5Z A;  4KP7 A;  4ARF A;  2DQM A;  4AR8 A;  5JAZ A;  5JNL A;  4RCV A;  4QME A;  3QJX A;  4QUO A;  4LUP A;  1SC5 A;  4Q4E A;  3T8V A;  1MW1 A;  5FWQ A;  3CZL A;  3FTV A;  4XN9 A;  3RAS A;  5BPP A;  1G5A A;  2R70 A;  2HPO A;  3CZE A;  5HNF A;  4J3B A;  3CZG A;  3FUD A;  4FLO A;  3FTS A;  3FH8 A;  3JSZ A;  3Q44 A;  1MW0 A;  4XO4 A;  2MAO A;  2QVW A;  3HW2 A;  4XMZ A;  3B2P A;  2DQ6 A;  3B3B A;  4RSY A;  1MVY A;  5JMP A;  3WQS B;  1SQM A;  1JVS A;  5DUL A;  5JMW A;  4FLR A;  4XND A;  4GAE A;  3FUI A;  4QIR A;  2R72 A;  1MW3 A;  2O7G A;  3ZI0 A;  3CXB A;  3FUE A;  4XN2 A;  3R0I A;  4K5L A;  4ZW7 A;  1R0L A;  4BKX A;  4XMT A;  3ANL A;  3FHE A;  2A7O A;  1T1R A;  2QJ1 A;  2XPY A;  2Y1D A;  3EBG A;  3FTX A;  2B61 A;  3B7S A;  5HNH A;  3WQR A;  2Y1E A;  1X3Z A;  3FU3 A;  3FUH A;  4K5N A;  1ONN A;  2JCX A;  3FTU A;  4PU2 A;  4Y6S A;  4Y6P A;  3AU9 A;  3B37 A;  4XN5 A;  1S46 A;  4NQW A;  4XMV A;  2GTQ A;  1T1S A;  3B7R L;  4ZW5 A;  4ZW3 A;  3B2X A;  5JO0 A;  2VLA A;  5DYF A;  2WPG A;  3ANN A;  3B7T A;  4GAA A;  3UER A;  3FU6 A;  3FUJ A;  4AR1 A;  3FTZ A;  3KED A;  5HLT A;  4QPE A;  1R0K A;  3FU0 A;  2HPT A;  5JC1 A;  4ZW6 A;  1H19 A;  3JT1 A;  1X3W A;  4R5T A;  4ZQF A;  2PGG A;  1HS6 A;  4DPR A;  4ZQG A;  3AU8 A;  4ZN6 A;  3ZHY A;  2JCY A;  4FLQ A;  2XPZ A;  3FUF A;  4XN4 A;  1ONP A;  1SG7 A;  4L2L A;  2MAP A;  1ZS2 A;  2JCV A;  3A06 A;  5AEN A;  4Y67 A;  4MKT A;  4ZW8 A;  2FFL A;  2WZG A;  4XN1 A;  2EGH A;  3ZHZ A;  4ZQH A;  4K5P A;  3B34 A;  2C82 A;  1MW2 A;  2PUS A;  2JD1 A;  3IIE A;  3PUU A;  3CZK A;  3RC3 A;  4R5X A;  4RVB A;  3FH7 A;  2JV7 A;  4XMW A;  5EV7 A;  3FH5 A;  1JG9 A;  2JD2 A;  3EBH A;  1JGI A;  4MS6 A;  3CIA A;  3UEQ A;  2WZF A;  3VVM A;  4A03 A;  4QHP A;  1OR7 A;  3FUL A;  3FUK A;  4OOE A;  4XMU A;  3ANM A;  5DLL A;  2PL5 A;  3UCQ A;  2Y1C A;  3FTY A;  3VVL A;  4XNB A;  2JD0 A;  2RJI A;  2Y1G A;  4JND A;  4Q4I A;  4ZX3 A;  3CHQ A;  4XO5 A;  3U9W A;  4FCA A;  3A14 A;  4XMX A;  4K5M A;  1Q0L A;  3CHO A;  3AUA A;  2Y1F A;  4ZX6 A;  2VJ8 A;  4XNA A;  4X2U A;  5JBI A;  1Q0Q A;  1K5H A;  1H3L A;  3FTW A;  3B7U X;  4PW4 A;  4XN8 A;  2ZXG A;  4OOF A;  4R5V A;  4ZX4 A;  4ZQE A;  4AR9 A; 
#chains in the Genus database with same CATH homology
 3RC8 A;  4XO3 A;  4XN7 A;  4AIC A;  3FU5 A;  3FUM A;  4ZQT A;  1Q0H A;  3T0Y A;  4AYS A;  4PVB A;  4K5O A;  1GW6 A;  3WQQ A;  3ZHX A;  4CXF A;  3CHR A;  1RP3 A;  2XQ0 A;  4R7L A;  3EBI A;  1ONO A;  3CHS A;  3Q43 A;  4Y6R A;  2R59 A;  4ZX5 A;  3FUN A;  4FLS A;  3CHP A;  2C5Z A;  4KP7 A;  4ARF A;  2DQM A;  4AR8 A;  5JAZ A;  5JNL A;  4RCV A;  4QME A;  3QJX A;  4QUO A;  4LUP A;  1SC5 A;  4Q4E A;  3T8V A;  1MW1 A;  5FWQ A;  3CZL A;  3FTV A;  4XN9 A;  3RAS A;  5BPP A;  1G5A A;  2R70 A;  2HPO A;  3CZE A;  5HNF A;  4J3B A;  3CZG A;  3FUD A;  4FLO A;  3FTS A;  3FH8 A;  3JSZ A;  3Q44 A;  1MW0 A;  4XO4 A;  2MAO A;  2QVW A;  4XMZ A;  3B2P A;  2DQ6 A;  3B3B A;  4RSY A;  1MVY A;  5JMP A;  3WQS B;  1SQM A;  1JVS A;  5DUL A;  5JMW A;  4FLR A;  4XND A;  4GAE A;  3FUI A;  4QIR A;  2R72 A;  1MW3 A;  2O7G A;  3ZI0 A;  4XN2 A;  3FUE A;  4ZW7 A;  3R0I A;  4K5L A;  4BKX A;  1R0L A;  4XMT A;  3ANL A;  3FHE A;  2A7O A;  1T1R A;  2QJ1 A;  2XPY A;  2Y1D A;  3EBG A;  3FTX A;  2B61 A;  3B7S A;  5HNH A;  3WQR A;  2Y1E A;  1X3Z A;  3FU3 A;  3FUH A;  4K5N A;  1ONN A;  2JCX A;  3FTU A;  4PU2 A;  4Y6S A;  4Y6P A;  3AU9 A;  3B37 A;  4XN5 A;  1S46 A;  4NQW A;  4XMV A;  2GTQ A;  1T1S A;  3B7R L;  4ZW5 A;  4ZW3 A;  3B2X A;  5JO0 A;  2VLA A;  5DYF A;  2WPG A;  3ANN A;  3B7T A;  4GAA A;  3UER A;  3FU6 A;  3FUJ A;  4AR1 A;  3FTZ A;  3KED A;  5HLT A;  4QPE A;  1R0K A;  3FU0 A;  2HPT A;  5JC1 A;  4ZW6 A;  1H19 A;  3JT1 A;  1X3W A;  4R5T A;  4ZQF A;  2PGG A;  1HS6 A;  4DPR A;  4ZQG A;  3AU8 A;  4ZN6 A;  3ZHY A;  2JCY A;  4FLQ A;  2XPZ A;  3FUF A;  4XN4 A;  1ONP A;  1SG7 A;  4L2L A;  2MAP A;  1ZS2 A;  2JCV A;  3A06 A;  5AEN A;  4Y67 A;  4MKT A;  4ZW8 A;  2FFL A;  2WZG A;  4XN1 A;  2EGH A;  3ZHZ A;  4ZQH A;  4K5P A;  3B34 A;  2C82 A;  1MW2 A;  2PUS A;  2JD1 A;  3IIE A;  3PUU A;  3CZK A;  3RC3 A;  4R5X A;  4RVB A;  3FH7 A;  2JV7 A;  4XMW A;  5EV7 A;  3FH5 A;  1JG9 A;  2JD2 A;  3EBH A;  1JGI A;  4MS6 A;  3CIA A;  3UEQ A;  2WZF A;  3VVM A;  4A03 A;  4QHP A;  1OR7 A;  3FUL A;  3FUK A;  4OOE A;  4XMU A;  3ANM A;  5DLL A;  2PL5 A;  3UCQ A;  2Y1C A;  3FTY A;  3VVL A;  4XNB A;  2JD0 A;  2RJI A;  2Y1G A;  4JND A;  4Q4I A;  4ZX3 A;  3CHQ A;  4XO5 A;  3U9W A;  4FCA A;  3A14 A;  4XMX A;  4K5M A;  1Q0L A;  3CHO A;  3AUA A;  2Y1F A;  4ZX6 A;  2VJ8 A;  4XNA A;  4X2U A;  5JBI A;  1Q0Q A;  1K5H A;  1H3L A;  3FTW A;  3B7U X;  4PW4 A;  4XN8 A;  2ZXG A;  4OOF A;  4R5V A;  4ZX4 A;  4ZQE A;  4AR9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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