4LUPA

Crystal structure of the complex formed by region of e. coli sigmae bound to its -10 element non template strand
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
91
structure length
91
Chain Sequence
LTDQVLVERVQKGDQKAFNLLVVRYQHKVASLVSRYVPSGDVPDVVQEAFIKAYRALDSFRGDSAFYTWLYRIAVNTAKNYLVAQGRRLEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for -10 promoter element melting by environmentally induced sigma factors.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Escherichia coli
molecule keywords RNA polymerase sigma factor
total genus 36
structure length 91
sequence length 91
chains with identical sequence C
ec nomenclature
pdb deposition date 2013-07-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04542 Sigma70_r2 Sigma-70 region 2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1740.10 Mainly Alpha Orthogonal Bundle Rna Polymerase Sigma Factor; Chain: A Rna Polymerase Sigma Factor; Chain: A 4lupA00
1ONPA 5JC1A 4FLRA 1MW0A 4Y6PA 3ANNA 4Y67A 3CZKA 3AU9A 4ZQFA 1MW2A 3UEQA 4LUPA 3A06A 3ZHXA 4NQWA 4AYSA 1SC5A 3ZHYA 2JD0A 1Q0LA 1ONOA 3A14A 1R0KA 2Y1CA 4A03A 2JCXA 3R0IA 4OOEA 1JVSA 3AUAA 1R0LA 1JGIA 4OOFA 1K5HA 5JO0A 5JBIA 2O7GA 4ZQGA 2JD1A 1Q0QA 3CZGA 4FLSA 1OR7A 1JG9A 2WPGA 4KP7A 5JMWA 1ZS2A 3ANMA 1MW3A 2Y1FA 1S46A 1ONNA 1Q0HA 2MAOA 4ZQEA 3ZHZA 1RP3A 3RASA 1G5AA 2EGHA 2Y1DA 2Y1EA 5JMPA 2JD2A 3WQRA 4ZN6A 2MAPA 1T1SA 4RCVA 1MVYA 3ANLA 3AU8A 2C82A 2JCYA 1H3LA 4Y6RA 3UCQA 4GAEA 4ZQHA 2Y1GA 4FLOA 4FLQA 1T1RA 3UERA 3T0YA 4AICA 3CZEA 2JCVA 3WQSB 3WQQA 5DULA 1MW1A 4CXFA 3ZI0A 5JNLA 3CZLA 3IIEA 5JAZA 4Y6SA
chains in the Genus database with same CATH superfamily
4XO5A 1ONPA 4XO3A 4PW4A 3B34A 5JC1A 4FLRA 1MW0A 2PUSA 4Y6PA 3ANNA 2VJ8A 3B7RL 3B3BA 3FH5A 5HNFA 3FTXA 3B37A 4Y67A 4ZW3A 2PGGA 3CZKA 3FHEA 4XMTA 3AU9A 3CHOA 4AR8A 4ZQFA 2VLAA 1MW2A 4XN5A 3UEQA 4K5NA 4QUOA 2ZXGA 4ZX3A 2XPYA 4LUPA 3A06A 3ZHXA 4NQWA 4AYSA 5BPPA 2JV7A 3B2XA 2RJIA 3FTWA 4JNDA 1SC5A 4RVBA 4Q4IA 3ZHYA 4XO4A 3FUMA 2JD0A 4QHPA 5AENA 4BKXA 1Q0LA 4R7LA 1ONOA 3FTUA 5HNHA 3A14A 3KEDA 1R0KA 3HW2A 4ZW6A 2DQ6A 2Y1CA 4A03A 3EBIA 2WZFA 2JCXA 3R0IA 4OOEA 1JVSA 3AUAA 1R0LA 3FUJA 3FUHA 1JGIA 3CHQA 4XN8A 3RC3A 4OOFA 1K5HA 4XN1A 2QJ1A 2XQ0A 2HPTA 5JBIA 5JO0A 1X3WA 2O7GA 4ZQGA 3FUIA 2JD1A 1Q0QA 5DYFA 1SG7A 5HLTA 4PU2A 3U9WA 4PVBA 3CHRA 3CZGA 4FLSA 2R70A 1OR7A 1JG9A 4K5OA 2WPGA 4XNDA 4KP7A 4Q4EA 3EBHA 3FTSA 3T8VA 2HPOA 5JMWA 1X3ZA 1ZS2A 3ANMA 3FTZA 3FUDA 1MW3A 2Y1FA 3IIEA 4XMXA 1S46A 4DPRA 4XMWA 2R72A 2B61A 2FFLA 4R5VA 4XN4A 4ZX4A 1ONNA 1Q0HA 4XNAA 2MAOA 1GW6A 4ZQEA 3ZHZA 4R5TA 1RP3A 3RASA 3B7TA 1G5AA 5EV7A 2WZGA 4GAAA 3CIAA 2EGHA 1H19A 2Y1DA 3JSZA 2Y1EA 5JMPA 2JD2A 2XPZA 2A7OA 3FU5A 4MKTA 4QPEA 3WQRA 4ZN6A 2MAPA 3FUFA 1T1SA 1SQMA 4RCVA 4XN9A 3RC8A 4XMVA 4X2UA 5FWQA 3FTVA 3VVMA 1MVYA 3CHPA 4ZX6A 3EBGA 3CXBA 3FH7A 3ANLA 3FU3A 4XNBA 3AU8A 1HS6A 4QIRA 3VVLA 2C82A 2JCYA 4ARFA 4K5MA 4ZQTA 1H3LA 4FCAA 3FUNA 4Y6RA 3Q43A 4XMZA 4GAEA 4ZQHA 2Y1GA 4FLOA 3UCQA 3FUEA 4ZW5A 4AR9A 3FUKA 4AR1A 4FLQA 1T1RA 4RSYA 3B7SA 3UERA 3FULA 3T0YA 3FH8A 3Q44A 3FU0A 4AICA 2C5ZA 4R5XA 2DQMA 4XN7A 5DLLA 2GTQA 3CZEA 2JCVA 2PL5A 4J3BA 4QMEA 4ZW8A 3WQSB 3FU6A 5DULA 3WQQA 1MW1A 4CXFA 3JT1A 3B7UX 4L2LA 3PUUA 4ZW7A 4XN2A 4K5PA 2QVWA 3ZI0A 5JNLA 3CHSA 4MS6A 4XMUA 3QJXA 3CZLA 3FTYA 4ZX5A 3B2PA 2R59A 5JAZA 4K5LA 4Y6SA
chains in the Genus database with same CATH topology
4XO5A 1ONPA 4XO3A 4PW4A 3B34A 5JC1A 4FLRA 1MW0A 2PUSA 4Y6PA 3ANNA 2VJ8A 3B7RL 3B3BA 3FH5A 5HNFA 3FTXA 3B37A 4Y67A 4ZW3A 2PGGA 3CZKA 3FHEA 4XMTA 3AU9A 3CHOA 4AR8A 4ZQFA 2VLAA 1MW2A 4XN5A 3UEQA 4K5NA 4QUOA 2ZXGA 4ZX3A 2XPYA 4LUPA 3A06A 3ZHXA 4NQWA 4AYSA 5BPPA 2JV7A 3B2XA 2RJIA 3FTWA 4JNDA 1SC5A 4RVBA 4Q4IA 3ZHYA 4XO4A 3FUMA 2JD0A 4QHPA 5AENA 4BKXA 1Q0LA 4R7LA 1ONOA 3FTUA 5HNHA 3A14A 3KEDA 1R0KA 4ZW6A 2DQ6A 2Y1CA 4A03A 3EBIA 2WZFA 2JCXA 3R0IA 4OOEA 1JVSA 3AUAA 1R0LA 3FUJA 3FUHA 1JGIA 3CHQA 4XN8A 3RC3A 4OOFA 1K5HA 4XN1A 2QJ1A 2XQ0A 2HPTA 5JBIA 5JO0A 1X3WA 2O7GA 4ZQGA 3FUIA 2JD1A 1Q0QA 5DYFA 1SG7A 5HLTA 4PU2A 3U9WA 4PVBA 3CHRA 3CZGA 4FLSA 2R70A 1OR7A 1JG9A 4K5OA 2WPGA 4XNDA 4KP7A 4Q4EA 3EBHA 3FTSA 3T8VA 2HPOA 5JMWA 1X3ZA 1ZS2A 3ANMA 3FTZA 3FUDA 1MW3A 2Y1FA 3IIEA 4XMXA 1S46A 4DPRA 4XMWA 2R72A 2B61A 2FFLA 4R5VA 4XN4A 4ZX4A 1ONNA 1Q0HA 4XNAA 2MAOA 1GW6A 4ZQEA 3ZHZA 4R5TA 1RP3A 3RASA 3B7TA 1G5AA 5EV7A 2WZGA 4GAAA 3CIAA 2EGHA 1H19A 2Y1DA 3JSZA 2Y1EA 5JMPA 2JD2A 2XPZA 2A7OA 3FU5A 4MKTA 4QPEA 3WQRA 4ZN6A 2MAPA 3FUFA 1T1SA 1SQMA 4RCVA 4XN9A 3RC8A 4XMVA 4X2UA 5FWQA 3FTVA 3VVMA 1MVYA 3CHPA 4ZX6A 3EBGA 3FH7A 3ANLA 3FU3A 4XNBA 3AU8A 1HS6A 4QIRA 3VVLA 2C82A 2JCYA 4ARFA 4K5MA 4ZQTA 1H3LA 4FCAA 3FUNA 4Y6RA 3Q43A 4XMZA 4GAEA 4ZQHA 2Y1GA 4FLOA 3UCQA 3FUEA 4ZW5A 4AR9A 3FUKA 4AR1A 4FLQA 1T1RA 4RSYA 3B7SA 3UERA 3FULA 3T0YA 3FH8A 3Q44A 3FU0A 4AICA 2C5ZA 4R5XA 2DQMA 4XN7A 5DLLA 2GTQA 3CZEA 2JCVA 2PL5A 4J3BA 4QMEA 4ZW8A 3WQSB 3FU6A 5DULA 3WQQA 1MW1A 4CXFA 3JT1A 3B7UX 4L2LA 3PUUA 4ZW7A 4XN2A 4K5PA 2QVWA 3ZI0A 5JNLA 3CHSA 4MS6A 4XMUA 3QJXA 3CZLA 3FTYA 4ZX5A 3B2PA 2R59A 5JAZA 4K5LA 4Y6SA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ONP A;  5JC1 A;  4FLR A;  1MW0 A;  4Y6P A;  3ANN A;  4Y67 A;  3CZK A;  3AU9 A;  4ZQF A;  1MW2 A;  3UEQ A;  4LUP A;  3A06 A;  3ZHX A;  4NQW A;  4AYS A;  1SC5 A;  3ZHY A;  2JD0 A;  1Q0L A;  1ONO A;  3A14 A;  1R0K A;  2Y1C A;  4A03 A;  2JCX A;  3R0I A;  4OOE A;  1JVS A;  3AUA A;  1R0L A;  1JGI A;  4OOF A;  1K5H A;  5JO0 A;  5JBI A;  2O7G A;  4ZQG A;  2JD1 A;  1Q0Q A;  3CZG A;  4FLS A;  1OR7 A;  1JG9 A;  2WPG A;  4KP7 A;  5JMW A;  1ZS2 A;  3ANM A;  1MW3 A;  2Y1F A;  1S46 A;  1ONN A;  1Q0H A;  2MAO A;  4ZQE A;  3ZHZ A;  1RP3 A;  3RAS A;  1G5A A;  2EGH A;  2Y1D A;  2Y1E A;  5JMP A;  2JD2 A;  3WQR A;  4ZN6 A;  2MAP A;  1T1S A;  4RCV A;  1MVY A;  3ANL A;  3AU8 A;  2C82 A;  2JCY A;  1H3L A;  4Y6R A;  3UCQ A;  4GAE A;  4ZQH A;  2Y1G A;  4FLO A;  4FLQ A;  1T1R A;  3UER A;  3T0Y A;  4AIC A;  3CZE A;  2JCV A;  3WQS B;  3WQQ A;  5DUL A;  1MW1 A;  4CXF A;  3ZI0 A;  5JNL A;  3CZL A;  3IIE A;  5JAZ A;  4Y6S A; 
#chains in the Genus database with same CATH topology
 4XO5 A;  1ONP A;  4XO3 A;  4PW4 A;  3B34 A;  5JC1 A;  4FLR A;  1MW0 A;  2PUS A;  4Y6P A;  3ANN A;  2VJ8 A;  3B7R L;  3B3B A;  3FH5 A;  5HNF A;  3FTX A;  3B37 A;  4Y67 A;  4ZW3 A;  2PGG A;  3CZK A;  3FHE A;  4XMT A;  3AU9 A;  3CHO A;  4AR8 A;  4ZQF A;  2VLA A;  1MW2 A;  4XN5 A;  3UEQ A;  4K5N A;  4QUO A;  2ZXG A;  4ZX3 A;  2XPY A;  4LUP A;  3A06 A;  3ZHX A;  4NQW A;  4AYS A;  5BPP A;  2JV7 A;  3B2X A;  2RJI A;  3FTW A;  4JND A;  1SC5 A;  4RVB A;  4Q4I A;  3ZHY A;  4XO4 A;  3FUM A;  2JD0 A;  4QHP A;  5AEN A;  4BKX A;  1Q0L A;  4R7L A;  1ONO A;  3FTU A;  5HNH A;  3A14 A;  3KED A;  1R0K A;  3HW2 A;  4ZW6 A;  2DQ6 A;  2Y1C A;  4A03 A;  3EBI A;  2WZF A;  2JCX A;  3R0I A;  4OOE A;  1JVS A;  3AUA A;  1R0L A;  3FUJ A;  3FUH A;  1JGI A;  3CHQ A;  4XN8 A;  3RC3 A;  4OOF A;  1K5H A;  4XN1 A;  2QJ1 A;  2XQ0 A;  2HPT A;  5JBI A;  5JO0 A;  1X3W A;  2O7G A;  4ZQG A;  3FUI A;  2JD1 A;  1Q0Q A;  5DYF A;  1SG7 A;  5HLT A;  4PU2 A;  3U9W A;  4PVB A;  3CHR A;  3CZG A;  4FLS A;  2R70 A;  1OR7 A;  1JG9 A;  4K5O A;  2WPG A;  4XND A;  4KP7 A;  4Q4E A;  3EBH A;  3FTS A;  3T8V A;  2HPO A;  5JMW A;  1X3Z A;  1ZS2 A;  3ANM A;  3FTZ A;  3FUD A;  1MW3 A;  2Y1F A;  3IIE A;  4XMX A;  1S46 A;  4DPR A;  4XMW A;  2R72 A;  2B61 A;  2FFL A;  4R5V A;  4XN4 A;  4ZX4 A;  1ONN A;  1Q0H A;  4XNA A;  2MAO A;  1GW6 A;  4ZQE A;  3ZHZ A;  4R5T A;  1RP3 A;  3RAS A;  3B7T A;  1G5A A;  5EV7 A;  2WZG A;  4GAA A;  3CIA A;  2EGH A;  1H19 A;  2Y1D A;  3JSZ A;  2Y1E A;  5JMP A;  2JD2 A;  2XPZ A;  2A7O A;  3FU5 A;  4MKT A;  4QPE A;  3WQR A;  4ZN6 A;  2MAP A;  3FUF A;  1T1S A;  1SQM A;  4RCV A;  4XN9 A;  3RC8 A;  4XMV A;  4X2U A;  5FWQ A;  3FTV A;  3VVM A;  1MVY A;  3CHP A;  4ZX6 A;  3EBG A;  3CXB A;  3FH7 A;  3ANL A;  3FU3 A;  4XNB A;  3AU8 A;  1HS6 A;  4QIR A;  3VVL A;  2C82 A;  2JCY A;  4ARF A;  4K5M A;  4ZQT A;  1H3L A;  4FCA A;  3FUN A;  4Y6R A;  3Q43 A;  4XMZ A;  4GAE A;  4ZQH A;  2Y1G A;  4FLO A;  3UCQ A;  3FUE A;  4ZW5 A;  4AR9 A;  3FUK A;  4AR1 A;  4FLQ A;  1T1R A;  4RSY A;  3B7S A;  3UER A;  3FUL A;  3T0Y A;  3FH8 A;  3Q44 A;  3FU0 A;  4AIC A;  2C5Z A;  4R5X A;  2DQM A;  4XN7 A;  5DLL A;  2GTQ A;  3CZE A;  2JCV A;  2PL5 A;  4J3B A;  4QME A;  4ZW8 A;  3WQS B;  3FU6 A;  5DUL A;  3WQQ A;  1MW1 A;  4CXF A;  3JT1 A;  3B7U X;  4L2L A;  3PUU A;  4ZW7 A;  4XN2 A;  4K5P A;  2QVW A;  3ZI0 A;  5JNL A;  3CHS A;  4MS6 A;  4XMU A;  3QJX A;  3CZL A;  3FTY A;  4ZX5 A;  3B2P A;  2R59 A;  5JAZ A;  4K5L A;  4Y6S A; 
#chains in the Genus database with same CATH homology
 4XO5 A;  1ONP A;  4XO3 A;  4PW4 A;  3B34 A;  5JC1 A;  4FLR A;  1MW0 A;  2PUS A;  4Y6P A;  3ANN A;  2VJ8 A;  3B7R L;  3B3B A;  3FH5 A;  5HNF A;  3FTX A;  3B37 A;  4Y67 A;  4ZW3 A;  2PGG A;  3CZK A;  3FHE A;  4XMT A;  3AU9 A;  3CHO A;  4AR8 A;  4ZQF A;  2VLA A;  1MW2 A;  4XN5 A;  3UEQ A;  4K5N A;  4QUO A;  2ZXG A;  4ZX3 A;  2XPY A;  4LUP A;  3A06 A;  3ZHX A;  4NQW A;  4AYS A;  5BPP A;  2JV7 A;  3B2X A;  2RJI A;  3FTW A;  4JND A;  1SC5 A;  4RVB A;  4Q4I A;  3ZHY A;  4XO4 A;  3FUM A;  2JD0 A;  4QHP A;  5AEN A;  4BKX A;  1Q0L A;  4R7L A;  1ONO A;  3FTU A;  5HNH A;  3A14 A;  3KED A;  1R0K A;  4ZW6 A;  2DQ6 A;  2Y1C A;  4A03 A;  3EBI A;  2WZF A;  2JCX A;  3R0I A;  4OOE A;  1JVS A;  3AUA A;  1R0L A;  3FUJ A;  3FUH A;  1JGI A;  3CHQ A;  4XN8 A;  3RC3 A;  4OOF A;  1K5H A;  4XN1 A;  2QJ1 A;  2XQ0 A;  2HPT A;  5JBI A;  5JO0 A;  1X3W A;  2O7G A;  4ZQG A;  3FUI A;  2JD1 A;  1Q0Q A;  5DYF A;  1SG7 A;  5HLT A;  4PU2 A;  3U9W A;  4PVB A;  3CHR A;  3CZG A;  4FLS A;  2R70 A;  1OR7 A;  1JG9 A;  4K5O A;  2WPG A;  4XND A;  4KP7 A;  4Q4E A;  3EBH A;  3FTS A;  3T8V A;  2HPO A;  5JMW A;  1X3Z A;  1ZS2 A;  3ANM A;  3FTZ A;  3FUD A;  1MW3 A;  2Y1F A;  3IIE A;  4XMX A;  1S46 A;  4DPR A;  4XMW A;  2R72 A;  2B61 A;  2FFL A;  4R5V A;  4XN4 A;  4ZX4 A;  1ONN A;  1Q0H A;  4XNA A;  2MAO A;  1GW6 A;  4ZQE A;  3ZHZ A;  4R5T A;  1RP3 A;  3RAS A;  3B7T A;  1G5A A;  5EV7 A;  2WZG A;  4GAA A;  3CIA A;  2EGH A;  1H19 A;  2Y1D A;  3JSZ A;  2Y1E A;  5JMP A;  2JD2 A;  2XPZ A;  2A7O A;  3FU5 A;  4MKT A;  4QPE A;  3WQR A;  4ZN6 A;  2MAP A;  3FUF A;  1T1S A;  1SQM A;  4RCV A;  4XN9 A;  3RC8 A;  4XMV A;  4X2U A;  5FWQ A;  3FTV A;  3VVM A;  1MVY A;  3CHP A;  4ZX6 A;  3EBG A;  3FH7 A;  3ANL A;  3FU3 A;  4XNB A;  3AU8 A;  1HS6 A;  4QIR A;  3VVL A;  2C82 A;  2JCY A;  4ARF A;  4K5M A;  4ZQT A;  1H3L A;  4FCA A;  3FUN A;  4Y6R A;  3Q43 A;  4XMZ A;  4GAE A;  4ZQH A;  2Y1G A;  4FLO A;  3UCQ A;  3FUE A;  4ZW5 A;  4AR9 A;  3FUK A;  4AR1 A;  4FLQ A;  1T1R A;  4RSY A;  3B7S A;  3UER A;  3FUL A;  3T0Y A;  3FH8 A;  3Q44 A;  3FU0 A;  4AIC A;  2C5Z A;  4R5X A;  2DQM A;  4XN7 A;  5DLL A;  2GTQ A;  3CZE A;  2JCV A;  2PL5 A;  4J3B A;  4QME A;  4ZW8 A;  3WQS B;  3FU6 A;  5DUL A;  3WQQ A;  1MW1 A;  4CXF A;  3JT1 A;  3B7U X;  4L2L A;  3PUU A;  4ZW7 A;  4XN2 A;  4K5P A;  2QVW A;  3ZI0 A;  5JNL A;  3CHS A;  4MS6 A;  4XMU A;  3QJX A;  3CZL A;  3FTY A;  4ZX5 A;  3B2P A;  2R59 A;  5JAZ A;  4K5L A;  4Y6S A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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