4TR6A

Crystal structure of dna polymerase sliding clamp from bacillus subtilis
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
380
structure length
380
Chain Sequence
SHMKFTIQKDRLVESVQDVLKAVSSRTTIPILTGIKIVASDDGVSFTGSDSDISIESFIPKEEGDKEIVTIEQPGSIVLQARFFSEIVKKLPMATVEIEVQNQYLTIIRSGKAEFNLNGLDADEYPHLPQIEEHHAIQIPTDLLKNLIRQTVFAVSTSETRPILTGVNWKVEQSELLCTATDSHRLALRKAKLDIPEDRSYNVVIPGKSLTELSKILDDNQELVDIVITETQVLFKAKNVLFFSRLLDGNYPDTTSLIPQDSKTEIIVNTKEFLQAIDRASLLAREGRNNVVKLSAKPAESIEISSNSPEIGKVVEAIVADQIEGEELNISFSPKYMLDALKVLEGAEIRVSFTGAMRPFLIRTPNDETIVQLILPVRTY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Differential Modes of Peptide Binding onto Replicative Sliding Clamps from Various Bacterial Origins.
pubmed doi rcsb
molecule tags Dna binding protein
source organism Bacillus subtilis
molecule keywords DNA polymerase III subunit beta
total genus 91
structure length 380
sequence length 380
chains with identical sequence B
ec nomenclature ec 2.7.7.7: DNA-directed DNA polymerase.
pdb deposition date 2014-06-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00712 DNA_pol3_beta DNA polymerase III beta subunit, N-terminal domain
A PF02767 DNA_pol3_beta_2 DNA polymerase III beta subunit, central domain
A PF02768 DNA_pol3_beta_3 DNA polymerase III beta subunit, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4tr6A01
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 4tr6A02
4K3MA 5CFKA 5E0VA 1VPKA 2AWAA 1PLQA 1ISQA 3LX2A 4K3QA 3P87A 1UD9A 2IX2A 3L0XA 1PLRA 5AUJA 4D2GA 2IX2B 4N9AA 4TR8A 5AGUA 2IJXA 3GPNA 2HIIC 3F1VA 3G65A 4OVHA 3P16A 4RKIA 3D1FA 5FVEA 2ZVWA 3G65B 5H0TA 4TR6A 2NTIC 3G65C 4PNWA 4N98A 3Q4KA 3F1WA 5JNED 3V61B 3FDSC 4MJRA 5AH4A 2ZVLA 1UL1A 1T6LA 2HIKC 4K3PA 3TBLA 5IWDA 1VYMA 4HK1A 4MJPA 4PNVA 3HSLX 5DAIA 2POLA 4TR7A 1DMLA 4S3IA 3BEPA 4K3SA 1VYJA 3GPMA 3P83A 5HACA 3U60F 1CZDA 3P91A 5E0TA 5FRQA 1RXMA 2HIIA 3L0WA 3I2MX 4N97A 3RB9A 2HIIB 2Z0LA 3Q4JA 4L6PA 2NTIA 3D1GA 5IXAA 1YYPA 3GGRC 3V60B 2IZOC 4TSZA 2NTIB 4YHRA 5E0UA 2ZVMA 2IO4A 2OD8A 4CS5A 3L10A 5IY4A 3PGEB 4PNUA 1JQJA 5AH2A 2HIKA 2IO4B 4MJQA 3U5ZF 1UNNA 3PWEA 3T0PA 2HIKB 3FDSD 1SXJF 4OVFA 1U76A 3A2FB 4K3KA 1B77A 4N99A 1MMIA 4N95A 4K3OA 1RXZA 3IFVA 4K74A 3GGRA 1IZ5A 3AIZC 4RJFA 3GGRB 2ZVVA 2IZOB 3A1JA 5AGVA 3D1EA 3A1JC 4K3RA 2AVTA 1AXCA 3QSBA 3Q4LA 3QSBB 1IZ4A 3K4XA 4OVGA 3U61F 1W60A 5B7OA 2XURA 1GE8A 3VKXA 4N94A 2ZVKA 4K3LA 3LX1A 3AIZA 3V62B 2IX2C 4L60A 5DA7A 4TRTA 1OK7A 4N96A 3HI8A 4ZTDA 1JQLA 3A1JB 3AIXA 1RWZA 3AIXB 5A6DA 3WGWA 1U7BA 1B8HA
chains in the Genus database with same CATH superfamily
4K3MA 5CFKA 5E0VA 1VPKA 2AWAA 1PLQA 1ISQA 3LX2A 4K3QA 3P87A 1UD9A 2IX2A 3L0XA 1PLRA 5AUJA 4D2GA 2IX2B 4N9AA 3L0XB 4TR8A 5AGUA 2IJXA 3GPNA 2HIIC 3F1VA 3G65A 4OVHA 3P16A 4RKIA 3D1FA 5FVEA 2ZVWA 3G65B 5H0TA 4TR6A 2NTIC 3G65C 4PNWA 4N98A 3Q4KA 3F1WA 5JNED 3V61B 3FDSC 4MJRA 5AH4A 2ZVLA 1UL1A 1T6LA 2HIKC 4K3PA 3TBLA 5IWDA 1VYMA 4HK1A 4MJPA 4PNVA 3HSLX 5DAIA 2POLA 4TR7A 1DMLA 4S3IA 3BEPA 4K3SA 1VYJA 3GPMA 3P83A 5HACA 3U60F 1CZDA 3P91A 5E0TA 5FRQA 1RXMA 2HIIA 3L0WA 3I2MX 4N97A 3RB9A 2HIIB 2Z0LA 3L0WB 3Q4JA 4L6PA 2NTIA 3D1GA 5IXAA 1YYPA 3GGRC 3V60B 2IZOC 4TSZA 2NTIB 4YHRA 5E0UA 2ZVMA 3PGEA 2IO4A 2OD8A 4CS5A 3L10A 5IY4A 3PGEB 4PNUA 1JQJA 5AH2A 2HIKA 3L10B 4MJQA 2IO4B 3U5ZF 1UNNA 3PWEA 3T0PA 2HIKB 3FDSD 1SXJF 4OVFA 1U76A 3A2FB 4K3KA 1B77A 4N99A 1MMIA 4N95A 4K3OA 1RXZA 3IFVA 4K74A 3GGRA 1IZ5A 3AIZC 4RJFA 3GGRB 2ZVVA 2IZOB 3A1JA 5AGVA 3D1EA 3A1JC 4K3RA 2AVTA 1AXCA 3QSBA 3Q4LA 3QSBB 1IZ4A 3K4XA 4OVGA 3U61F 1W60A 5B7OA 2XURA 1GE8A 3VKXA 4N94A 2ZVKA 4K3LA 3LX1A 3AIZA 3V62B 2IX2C 4L60A 5DA7A 4TRTA 1OK7A 4N96A 3HI8A 4ZTDA 1JQLA 3A1JB 3AIXA 1RWZA 3AIXB 5A6DA 3WGWA 1U7BA 1B8HA
chains in the Genus database with same CATH topology
4K3MA 5CFKA 5E0VA 1VPKA 2AWAA 1PLQA 1ISQA 3LX2A 4K3QA 3P87A 1UD9A 2IX2A 3L0XA 1PLRA 5AUJA 4D2GA 2IX2B 4N9AA 4TR8A 5AGUA 2IJXA 3GPNA 2HIIC 3F1VA 3G65A 4OVHA 3P16A 4RKIA 3D1FA 5FVEA 2ZVWA 3G65B 5H0TA 4TR6A 2NTIC 3G65C 4PNWA 4N98A 3Q4KA 3F1WA 5JNED 3V61B 3FDSC 4MJRA 5AH4A 2ZVLA 1UL1A 1T6LA 2HIKC 4K3PA 3TBLA 5IWDA 1VYMA 4HK1A 4MJPA 4PNVA 3HSLX 5DAIA 2POLA 4TR7A 1DMLA 4S3IA 3BEPA 4K3SA 1VYJA 3GPMA 3P83A 5HACA 3U60F 1CZDA 3P91A 5E0TA 5FRQA 1RXMA 2HIIA 3L0WA 3I2MX 4N97A 3RB9A 2HIIB 2Z0LA 3Q4JA 4L6PA 2NTIA 3D1GA 5IXAA 1YYPA 3GGRC 3V60B 2IZOC 4TSZA 2NTIB 4YHRA 5E0UA 2ZVMA 2IO4A 2OD8A 4CS5A 3L10A 5IY4A 3PGEB 4PNUA 1JQJA 5AH2A 2HIKA 2IO4B 4MJQA 3U5ZF 1UNNA 3PWEA 3T0PA 2HIKB 3FDSD 1SXJF 4OVFA 1U76A 3A2FB 4K3KA 1B77A 4N99A 1MMIA 4N95A 4K3OA 1RXZA 3IFVA 4K74A 3GGRA 1IZ5A 3AIZC 4RJFA 3GGRB 2ZVVA 2IZOB 3A1JA 5AGVA 3D1EA 3A1JC 4K3RA 2AVTA 1AXCA 3QSBA 3Q4LA 3QSBB 1IZ4A 3K4XA 4OVGA 3U61F 1W60A 5B7OA 2XURA 1GE8A 3VKXA 4N94A 2ZVKA 4K3LA 3LX1A 3AIZA 3V62B 2IX2C 4L60A 5DA7A 4TRTA 1OK7A 4N96A 3HI8A 4ZTDA 1JQLA 3A1JB 3AIXA 1RWZA 3AIXB 5A6DA 3WGWA 1U7BA 1B8HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4K3M A;  5CFK A;  5E0V A;  1VPK A;  2AWA A;  1PLQ A;  1ISQ A;  3LX2 A;  4K3Q A;  3P87 A;  1UD9 A;  2IX2 A;  3L0X A;  1PLR A;  5AUJ A;  4D2G A;  2IX2 B;  4N9A A;  4TR8 A;  5AGU A;  2IJX A;  3GPN A;  2HII C;  3F1V A;  3G65 A;  4OVH A;  3P16 A;  4RKI A;  3D1F A;  5FVE A;  2ZVW A;  3G65 B;  5H0T A;  4TR6 A;  2NTI C;  3G65 C;  4PNW A;  4N98 A;  3Q4K A;  3F1W A;  5JNE D;  3V61 B;  3FDS C;  4MJR A;  5AH4 A;  2ZVL A;  1UL1 A;  1T6L A;  2HIK C;  4K3P A;  3TBL A;  5IWD A;  1VYM A;  4HK1 A;  4MJP A;  4PNV A;  3HSL X;  5DAI A;  2POL A;  4TR7 A;  1DML A;  4S3I A;  3BEP A;  4K3S A;  1VYJ A;  3GPM A;  3P83 A;  5HAC A;  3U60 F;  1CZD A;  3P91 A;  5E0T A;  5FRQ A;  1RXM A;  2HII A;  3L0W A;  3I2M X;  4N97 A;  3RB9 A;  2HII B;  2Z0L A;  3Q4J A;  4L6P A;  2NTI A;  3D1G A;  5IXA A;  1YYP A;  3GGR C;  3V60 B;  2IZO C;  4TSZ A;  2NTI B;  4YHR A;  5E0U A;  2ZVM A;  2IO4 A;  2OD8 A;  4CS5 A;  3L10 A;  5IY4 A;  3PGE B;  4PNU A;  1JQJ A;  5AH2 A;  2HIK A;  2IO4 B;  4MJQ A;  3U5Z F;  1UNN A;  3PWE A;  3T0P A;  2HIK B;  3FDS D;  1SXJ F;  4OVF A;  1U76 A;  3A2F B;  4K3K A;  1B77 A;  4N99 A;  1MMI A;  4N95 A;  4K3O A;  1RXZ A;  3IFV A;  4K74 A;  3GGR A;  1IZ5 A;  3AIZ C;  4RJF A;  3GGR B;  2ZVV A;  2IZO B;  3A1J A;  5AGV A;  3D1E A;  3A1J C;  4K3R A;  2AVT A;  1AXC A;  3QSB A;  3Q4L A;  3QSB B;  1IZ4 A;  3K4X A;  4OVG A;  3U61 F;  1W60 A;  5B7O A;  2XUR A;  1GE8 A;  3VKX A;  4N94 A;  2ZVK A;  4K3L A;  3LX1 A;  3AIZ A;  3V62 B;  2IX2 C;  4L60 A;  5DA7 A;  4TRT A;  1OK7 A;  4N96 A;  3HI8 A;  4ZTD A;  1JQL A;  3A1J B;  3AIX A;  1RWZ A;  3AIX B;  5A6D A;  3WGW A;  1U7B A;  1B8H A; 
#chains in the Genus database with same CATH topology
 4K3M A;  5CFK A;  5E0V A;  1VPK A;  2AWA A;  1PLQ A;  1ISQ A;  3LX2 A;  4K3Q A;  3P87 A;  1UD9 A;  2IX2 A;  3L0X A;  1PLR A;  5AUJ A;  4D2G A;  2IX2 B;  4N9A A;  3L0X B;  4TR8 A;  5AGU A;  2IJX A;  3GPN A;  2HII C;  3F1V A;  3G65 A;  4OVH A;  3P16 A;  4RKI A;  3D1F A;  5FVE A;  2ZVW A;  3G65 B;  5H0T A;  4TR6 A;  2NTI C;  3G65 C;  4PNW A;  4N98 A;  3Q4K A;  3F1W A;  5JNE D;  3V61 B;  3FDS C;  4MJR A;  5AH4 A;  2ZVL A;  1UL1 A;  1T6L A;  2HIK C;  4K3P A;  3TBL A;  5IWD A;  1VYM A;  4HK1 A;  4MJP A;  4PNV A;  3HSL X;  5DAI A;  2POL A;  4TR7 A;  1DML A;  4S3I A;  3BEP A;  4K3S A;  1VYJ A;  3GPM A;  3P83 A;  5HAC A;  3U60 F;  1CZD A;  3P91 A;  5E0T A;  5FRQ A;  1RXM A;  2HII A;  3L0W A;  3I2M X;  4N97 A;  3RB9 A;  2HII B;  2Z0L A;  3L0W B;  3Q4J A;  4L6P A;  2NTI A;  3D1G A;  5IXA A;  1YYP A;  3GGR C;  3V60 B;  2IZO C;  4TSZ A;  2NTI B;  4YHR A;  5E0U A;  2ZVM A;  3PGE A;  2IO4 A;  2OD8 A;  4CS5 A;  3L10 A;  5IY4 A;  3PGE B;  4PNU A;  1JQJ A;  5AH2 A;  2HIK A;  3L10 B;  4MJQ A;  2IO4 B;  3U5Z F;  1UNN A;  3PWE A;  3T0P A;  2HIK B;  3FDS D;  1SXJ F;  4OVF A;  1U76 A;  3A2F B;  4K3K A;  1B77 A;  4N99 A;  1MMI A;  4N95 A;  4K3O A;  1RXZ A;  3IFV A;  4K74 A;  3GGR A;  1IZ5 A;  3AIZ C;  4RJF A;  3GGR B;  2ZVV A;  2IZO B;  3A1J A;  5AGV A;  3D1E A;  3A1J C;  4K3R A;  2AVT A;  1AXC A;  3QSB A;  3Q4L A;  3QSB B;  1IZ4 A;  3K4X A;  4OVG A;  3U61 F;  1W60 A;  5B7O A;  2XUR A;  1GE8 A;  3VKX A;  4N94 A;  2ZVK A;  4K3L A;  3LX1 A;  3AIZ A;  3V62 B;  2IX2 C;  4L60 A;  5DA7 A;  4TRT A;  1OK7 A;  4N96 A;  3HI8 A;  4ZTD A;  1JQL A;  3A1J B;  3AIX A;  1RWZ A;  3AIX B;  5A6D A;  3WGW A;  1U7B A;  1B8H A; 
#chains in the Genus database with same CATH homology
 4K3M A;  5CFK A;  5E0V A;  1VPK A;  2AWA A;  1PLQ A;  1ISQ A;  3LX2 A;  4K3Q A;  3P87 A;  1UD9 A;  2IX2 A;  3L0X A;  1PLR A;  5AUJ A;  4D2G A;  2IX2 B;  4N9A A;  4TR8 A;  5AGU A;  2IJX A;  3GPN A;  2HII C;  3F1V A;  3G65 A;  4OVH A;  3P16 A;  4RKI A;  3D1F A;  5FVE A;  2ZVW A;  3G65 B;  5H0T A;  4TR6 A;  2NTI C;  3G65 C;  4PNW A;  4N98 A;  3Q4K A;  3F1W A;  5JNE D;  3V61 B;  3FDS C;  4MJR A;  5AH4 A;  2ZVL A;  1UL1 A;  1T6L A;  2HIK C;  4K3P A;  3TBL A;  5IWD A;  1VYM A;  4HK1 A;  4MJP A;  4PNV A;  3HSL X;  5DAI A;  2POL A;  4TR7 A;  1DML A;  4S3I A;  3BEP A;  4K3S A;  1VYJ A;  3GPM A;  3P83 A;  5HAC A;  3U60 F;  1CZD A;  3P91 A;  5E0T A;  5FRQ A;  1RXM A;  2HII A;  3L0W A;  3I2M X;  4N97 A;  3RB9 A;  2HII B;  2Z0L A;  3Q4J A;  4L6P A;  2NTI A;  3D1G A;  5IXA A;  1YYP A;  3GGR C;  3V60 B;  2IZO C;  4TSZ A;  2NTI B;  4YHR A;  5E0U A;  2ZVM A;  2IO4 A;  2OD8 A;  4CS5 A;  3L10 A;  5IY4 A;  3PGE B;  4PNU A;  1JQJ A;  5AH2 A;  2HIK A;  2IO4 B;  4MJQ A;  3U5Z F;  1UNN A;  3PWE A;  3T0P A;  2HIK B;  3FDS D;  1SXJ F;  4OVF A;  1U76 A;  3A2F B;  4K3K A;  1B77 A;  4N99 A;  1MMI A;  4N95 A;  4K3O A;  1RXZ A;  3IFV A;  4K74 A;  3GGR A;  1IZ5 A;  3AIZ C;  4RJF A;  3GGR B;  2ZVV A;  2IZO B;  3A1J A;  5AGV A;  3D1E A;  3A1J C;  4K3R A;  2AVT A;  1AXC A;  3QSB A;  3Q4L A;  3QSB B;  1IZ4 A;  3K4X A;  4OVG A;  3U61 F;  1W60 A;  5B7O A;  2XUR A;  1GE8 A;  3VKX A;  4N94 A;  2ZVK A;  4K3L A;  3LX1 A;  3AIZ A;  3V62 B;  2IX2 C;  4L60 A;  5DA7 A;  4TRT A;  1OK7 A;  4N96 A;  3HI8 A;  4ZTD A;  1JQL A;  3A1J B;  3AIX A;  1RWZ A;  3AIX B;  5A6D A;  3WGW A;  1U7B A;  1B8H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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