The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
88
|
sequence length |
275
|
structure length |
275
|
Chain Sequence |
LYEDPPDQKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQCPLKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites.
pubmed doi rcsb |
| molecule keywords |
AP ENDONUCLEASE 1
|
| molecule tags |
Dna repair
|
| source organism |
Homo sapiens
|
| total genus |
88
|
| structure length |
275
|
| sequence length |
275
|
| ec nomenclature |
ec
4.2.99.18: DNA-(apurinic or apyrimidinic site) lyase. |
| pdb deposition date | 1998-06-19 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF03372 | Exo_endo_phos | Endonuclease/Exonuclease/phosphatase family |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | 4-Layer Sandwich | Deoxyribonuclease I; Chain A | Endonuclease/exonuclease/phosphatase |
#chains in the Genus database with same CATH superfamily 1I9Y A; 2DDR A; 2V0R A; 3G0A A; 4GYZ A; 4F1R A; 5J8N A; 4GZ2 A; 2JC4 A; 2DNJ A; 3U8U A; 4B5I A; 2D1K B; 1ATN D; 5DG0 A; 3I41 A; 4F1H B; 2VOA A; 4L20 A; 3I46 A; 1SR4 B; 3K55 A; 2EI9 A; 1NTF A; 2V0S A; 5DFF A; 1DNK A; 4FPV A; 3NR8 A; 3G2D A; 5J3Z A; 3I48 A; 4LND A; 3MTC A; 2DDS A; 3NGN A; 4A9C A; 2XSW A; 2IMQ X; 2O3H A; 3G00 A; 5J3P A; 1BIX A; 3G0R A; 3W2Y A; 2F1N A; 2F2F B; 1YJH A; 2A40 B; 3DNI A; 1DE8 A; 1E9N A; 5INL A; 2A3Z B; 4QHD A; 1HD7 A; 1I9Z A; 5CFE A; 3TEB A; 4JG3 A; 5A7J A; 3G91 A; 5INK A; 4GEW A; 4QH9 A; 2O3C A; 3G3C A; 1WDU A; 4GZ0 A; 4B5M A; 5INO A; 4FVA A; 5INP A; 1DEW A; 4K6L F; 4B5F A; 3W3D B; 5J42 A; 3NGO A; 3FZI A; 5J3S A; 4L21 A; 4GZ1 A; 3G4T A; 1SI6 X; 2DDT A; 4QHE A; 4F1I A; 3G1K A; 3G6S A; 3L1W A; 5DV2 A; 4AWN A; 3I5V A; 3MPR A; 4CML A; 5DFI A; 4B5G A; 2J63 A; 5INM A; 1VYB A; 3GA6 A; 5DFJ A; 3WCX A; 4IEM A; 4B5J A; 3G2C A; 1Y21 A; 4F1H A; 2UYR X; 4CMN A; 2A42 B; 2JC5 A; 4B5H A; 4L1Z A; 1DE9 A; 3W2X A; 3N9V A; 4L1Y A; 5DV4 A; 5INN A; 3G8V A; 5DFH A; 4RUW A; 5A7I A; 3G38 A; 5INQ A; 2A41 B; 5EWT A; 3G3Y A; 1ZWX A; 3CJC D; 5HT2 A; 3NGQ A; 4PUQ A; 5CFG A; 2ISI A; 1AKO A; 4C1R A; #chains in the Genus database with same CATH topology 1I9Y A; 2DDR A; 2V0R A; 3G0A A; 4GYZ A; 4F1R A; 5J8N A; 4GZ2 A; 2JC4 A; 2DNJ A; 3U8U A; 4B5I A; 2D1K B; 1ATN D; 5DG0 A; 3I41 A; 4F1H B; 2VOA A; 4L20 A; 3I46 A; 1SR4 B; 3K55 A; 2EI9 A; 1NTF A; 2V0S A; 5DFF A; 1DNK A; 4FPV A; 3NR8 A; 3G2D A; 5J3Z A; 3I48 A; 4LND A; 3MTC A; 2DDS A; 3NGN A; 4A9C A; 2XSW A; 2IMQ X; 2O3H A; 3G00 A; 5J3P A; 1BIX A; 3G0R A; 3W2Y A; 2F1N A; 2F2F B; 1YJH A; 2A40 B; 3DNI A; 1DE8 A; 1E9N A; 5INL A; 2A3Z B; 4QHD A; 1HD7 A; 1I9Z A; 5CFE A; 3TEB A; 4JG3 A; 5A7J A; 3G91 A; 5INK A; 4GEW A; 4QH9 A; 2O3C A; 3G3C A; 1WDU A; 4GZ0 A; 4B5M A; 5INO A; 4FVA A; 5INP A; 1DEW A; 4K6L F; 4B5F A; 3W3D B; 5J42 A; 3NGO A; 3FZI A; 5J3S A; 4L21 A; 4GZ1 A; 3G4T A; 1SI6 X; 2DDT A; 4QHE A; 4F1I A; 3G1K A; 3G6S A; 3L1W A; 5DV2 A; 4AWN A; 3I5V A; 3MPR A; 4CML A; 5DFI A; 4B5G A; 2J63 A; 5INM A; 1VYB A; 3GA6 A; 5DFJ A; 3WCX A; 4IEM A; 4B5J A; 3G2C A; 1Y21 A; 4F1H A; 2UYR X; 4CMN A; 2A42 B; 2JC5 A; 4B5H A; 4L1Z A; 1DE9 A; 3W2X A; 3N9V A; 4L1Y A; 5DV4 A; 5INN A; 3G8V A; 5DFH A; 4RUW A; 5A7I A; 3G38 A; 5INQ A; 2A41 B; 5EWT A; 3G3Y A; 1ZWX A; 3CJC D; 5HT2 A; 3NGQ A; 4PUQ A; 5CFG A; 2ISI A; 1AKO A; 4C1R A; #chains in the Genus database with same CATH homology 1I9Y A; 2DDR A; 2V0R A; 3G0A A; 4GYZ A; 4F1R A; 5J8N A; 4GZ2 A; 2JC4 A; 2DNJ A; 3U8U A; 4B5I A; 2D1K B; 1ATN D; 5DG0 A; 3I41 A; 4F1H B; 2VOA A; 4L20 A; 3I46 A; 1SR4 B; 3K55 A; 2EI9 A; 1NTF A; 2V0S A; 5DFF A; 1DNK A; 4FPV A; 3NR8 A; 3G2D A; 5J3Z A; 3I48 A; 4LND A; 3MTC A; 2DDS A; 3NGN A; 4A9C A; 2XSW A; 2IMQ X; 2O3H A; 3G00 A; 5J3P A; 1BIX A; 3G0R A; 3W2Y A; 2F1N A; 2F2F B; 1YJH A; 2A40 B; 3DNI A; 1DE8 A; 1E9N A; 5INL A; 2A3Z B; 4QHD A; 1HD7 A; 1I9Z A; 5CFE A; 3TEB A; 4JG3 A; 5A7J A; 3G91 A; 5INK A; 4GEW A; 4QH9 A; 2O3C A; 3G3C A; 1WDU A; 4GZ0 A; 4B5M A; 5INO A; 4FVA A; 5INP A; 1DEW A; 4K6L F; 4B5F A; 3W3D B; 5J42 A; 3NGO A; 3FZI A; 5J3S A; 4L21 A; 4GZ1 A; 3G4T A; 1SI6 X; 2DDT A; 4QHE A; 4F1I A; 3G1K A; 3G6S A; 3L1W A; 5DV2 A; 4AWN A; 3I5V A; 3MPR A; 4CML A; 5DFI A; 4B5G A; 2J63 A; 5INM A; 1VYB A; 3GA6 A; 5DFJ A; 3WCX A; 4IEM A; 4B5J A; 3G2C A; 1Y21 A; 4F1H A; 2UYR X; 4CMN A; 2A42 B; 2JC5 A; 4B5H A; 4L1Z A; 1DE9 A; 3W2X A; 3N9V A; 4L1Y A; 5DV4 A; 5INN A; 3G8V A; 5DFH A; 4RUW A; 5A7I A; 3G38 A; 5INQ A; 2A41 B; 5EWT A; 3G3Y A; 1ZWX A; 3CJC D; 5HT2 A; 3NGQ A; 4PUQ A; 5CFG A; 2ISI A; 1AKO A; 4C1R A;
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