5A7IA

Crystal structure of inpp5b in complex with biphenyl 3,3',4,4',5,5'- hexakisphosphate
Total Genus 89
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
313
structure length
313
Chain Sequence
MYTYIQNFRFFAGTYNVNGQSPKECLRLWLSNGIQAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPLTISNHDVILWLGDLNYRIEELDVEKVKKLIEEKDFQMLYAYDQLKIQVAAKTVFEGFTEGELTFQPTYKYDTGSDDWDTSEKCRAPAWCDRILWKGKNITQLSYQSHMALKTSDHKPVSSVFDIGVRVVAHHHHHH
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal Structures of Type-II Inositol Polyphosphate 5-Phosphatase Inpp5B with Synthetic Inositol Polyphosphate Surrogates Reveal New Mechanistic Insights for the Inositol 5-Phosphatase Family.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords TYPE II INOSITOL 1,4,5-TRISPHOSPHATE 5-PHOSPHATASE
total genus 89
structure length 313
sequence length 313
ec nomenclature ec 3.1.3.36: Phosphoinositide 5-phosphatase.
pdb deposition date 2015-07-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 5a7iA00
5J8NA 4FPVA 2F1NA 2O3CA 4F1HB 1DEWA 3NGOA 5A7JA 4GZ0A 5DFIA 5J3PA 5CFEA 3W3DB 4K6LF 1WDUA 2V0SA 2JC4A 3G3YA 4B5JA 3DNIA 2DDRA 5INNA 1BIXA 4F1IA 1SR4B 3FZIA 2JC5A 2UYRX 3W2XA 5INMA 4B5GA 5INKA 2A40B 1VYBA 1DE9A 5DV4A 4GZ1A 4LNDA 2D1KB 3I5VA 2ISIA 3G2CA 1ATND 1HD7A 4B5MA 4JG3A 4B5HA 4QHDA 3G0RA 1DE8A 3GA6A 3G00A 3I41A 3I46A 4GEWA 2EI9A 4QHEA 3G38A 3K55A 4PUQA 2A42B 3NR8A 5EWTA 3MTCA 1I9YA 3I48A 3NGQA 3G2DA 2F2FB 3L1WA 4QH9A 5CFGA 4RUWA 3TEBA 2A3ZB 5DG0A 2O3HA 5INQA 3N9VA 5INPA 1E9NA 5DV2A 3G4TA 1AKOA 1I9ZA 1NTFA 3G0AA 5DFHA 4IEMA 3MPRA 5HT2A 3G3CA 4L21A 3U8UA 5J42A 5DFFA 2J63A 4FVAA 1ZWXA 4L20A 2IMQX 1DNKA 2A41B 2XSWA 1SI6X 1YJHA 4A9CA 4L1YA 5INOA 4B5FA 4B5IA 4F1RA 4L1ZA 3NGNA 4GZ2A 2DDTA 4CMLA 2VOAA 4GYZA 3G1KA 5J3SA 3G8VA 4F1HA 2V0RA 5A7IA 4CMNA 3G6SA 5DFJA 3G91A 5INLA 1Y21A 2DNJA 2DDSA 3WCXA 4AWNA 5J3ZA 3CJCD 3W2YA 4C1RA
chains in the Genus database with same CATH superfamily
5J8NA 4FPVA 2F1NA 2O3CA 4F1HB 1DEWA 3NGOA 5A7JA 4GZ0A 5DFIA 5J3PA 5CFEA 3W3DB 4K6LF 1WDUA 2V0SA 2JC4A 3G3YA 4B5JA 3DNIA 2DDRA 5INNA 1BIXA 4F1IA 1SR4B 3FZIA 2JC5A 2UYRX 3W2XA 5INMA 4B5GA 5INKA 2A40B 1VYBA 1DE9A 5DV4A 4GZ1A 4LNDA 2D1KB 3I5VA 2ISIA 3G2CA 1ATND 1HD7A 4B5MA 4JG3A 4B5HA 4QHDA 3G0RA 1DE8A 3GA6A 3G00A 3I41A 3I46A 4GEWA 2EI9A 4QHEA 3G38A 3K55A 4PUQA 2A42B 3NR8A 5EWTA 3MTCA 1I9YA 3I48A 3NGQA 3G2DA 2F2FB 3L1WA 4QH9A 5CFGA 4RUWA 3TEBA 2A3ZB 5DG0A 2O3HA 5INQA 3N9VA 5INPA 1E9NA 5DV2A 3G4TA 1AKOA 1I9ZA 1NTFA 3G0AA 5DFHA 4IEMA 3MPRA 5HT2A 3G3CA 4L21A 3U8UA 5J42A 5DFFA 2J63A 4FVAA 1ZWXA 4L20A 2IMQX 1DNKA 2A41B 2XSWA 1SI6X 1YJHA 4A9CA 4L1YA 5INOA 4B5FA 4B5IA 4F1RA 4L1ZA 3NGNA 4GZ2A 2DDTA 4CMLA 2VOAA 4GYZA 3G1KA 5J3SA 3G8VA 4F1HA 2V0RA 5A7IA 4CMNA 3G6SA 5DFJA 3G91A 5INLA 1Y21A 2DNJA 2DDSA 3WCXA 4AWNA 5J3ZA 3CJCD 3W2YA 4C1RA
chains in the Genus database with same CATH topology
5J8NA 4FPVA 2F1NA 2O3CA 4F1HB 1DEWA 3NGOA 5A7JA 4GZ0A 5DFIA 5J3PA 5CFEA 3W3DB 4K6LF 1WDUA 2V0SA 2JC4A 3G3YA 4B5JA 3DNIA 2DDRA 5INNA 1BIXA 4F1IA 1SR4B 3FZIA 2JC5A 2UYRX 3W2XA 5INMA 4B5GA 5INKA 2A40B 1VYBA 1DE9A 5DV4A 4GZ1A 4LNDA 2D1KB 3I5VA 2ISIA 3G2CA 1ATND 1HD7A 4B5MA 4JG3A 4B5HA 4QHDA 3G0RA 1DE8A 3GA6A 3G00A 3I41A 3I46A 4GEWA 2EI9A 4QHEA 3G38A 3K55A 4PUQA 2A42B 3NR8A 5EWTA 3MTCA 1I9YA 3I48A 3NGQA 3G2DA 2F2FB 3L1WA 4QH9A 5CFGA 4RUWA 3TEBA 2A3ZB 5DG0A 2O3HA 5INQA 3N9VA 5INPA 1E9NA 5DV2A 3G4TA 1AKOA 1I9ZA 1NTFA 3G0AA 5DFHA 4IEMA 3MPRA 5HT2A 3G3CA 4L21A 3U8UA 5J42A 5DFFA 2J63A 4FVAA 1ZWXA 4L20A 2IMQX 1DNKA 2A41B 2XSWA 1SI6X 1YJHA 4A9CA 4L1YA 5INOA 4B5FA 4B5IA 4F1RA 4L1ZA 3NGNA 4GZ2A 2DDTA 4CMLA 2VOAA 4GYZA 3G1KA 5J3SA 3G8VA 4F1HA 2V0RA 5A7IA 4CMNA 3G6SA 5DFJA 3G91A 5INLA 1Y21A 2DNJA 2DDSA 3WCXA 4AWNA 5J3ZA 3CJCD 3W2YA 4C1RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5J8N A;  4FPV A;  2F1N A;  2O3C A;  4F1H B;  1DEW A;  3NGO A;  5A7J A;  4GZ0 A;  5DFI A;  5J3P A;  5CFE A;  3W3D B;  4K6L F;  1WDU A;  2V0S A;  2JC4 A;  3G3Y A;  4B5J A;  3DNI A;  2DDR A;  5INN A;  1BIX A;  4F1I A;  1SR4 B;  3FZI A;  2JC5 A;  2UYR X;  3W2X A;  5INM A;  4B5G A;  5INK A;  2A40 B;  1VYB A;  1DE9 A;  5DV4 A;  4GZ1 A;  4LND A;  2D1K B;  3I5V A;  2ISI A;  3G2C A;  1ATN D;  1HD7 A;  4B5M A;  4JG3 A;  4B5H A;  4QHD A;  3G0R A;  1DE8 A;  3GA6 A;  3G00 A;  3I41 A;  3I46 A;  4GEW A;  2EI9 A;  4QHE A;  3G38 A;  3K55 A;  4PUQ A;  2A42 B;  3NR8 A;  5EWT A;  3MTC A;  1I9Y A;  3I48 A;  3NGQ A;  3G2D A;  2F2F B;  3L1W A;  4QH9 A;  5CFG A;  4RUW A;  3TEB A;  2A3Z B;  5DG0 A;  2O3H A;  5INQ A;  3N9V A;  5INP A;  1E9N A;  5DV2 A;  3G4T A;  1AKO A;  1I9Z A;  1NTF A;  3G0A A;  5DFH A;  4IEM A;  3MPR A;  5HT2 A;  3G3C A;  4L21 A;  3U8U A;  5J42 A;  5DFF A;  2J63 A;  4FVA A;  1ZWX A;  4L20 A;  2IMQ X;  1DNK A;  2A41 B;  2XSW A;  1SI6 X;  1YJH A;  4A9C A;  4L1Y A;  5INO A;  4B5F A;  4B5I A;  4F1R A;  4L1Z A;  3NGN A;  4GZ2 A;  2DDT A;  4CML A;  2VOA A;  4GYZ A;  3G1K A;  5J3S A;  3G8V A;  4F1H A;  2V0R A;  5A7I A;  4CMN A;  3G6S A;  5DFJ A;  3G91 A;  5INL A;  1Y21 A;  2DNJ A;  2DDS A;  3WCX A;  4AWN A;  5J3Z A;  3CJC D;  3W2Y A;  4C1R A; 
#chains in the Genus database with same CATH topology
 5J8N A;  4FPV A;  2F1N A;  2O3C A;  4F1H B;  1DEW A;  3NGO A;  5A7J A;  4GZ0 A;  5DFI A;  5J3P A;  5CFE A;  3W3D B;  4K6L F;  1WDU A;  2V0S A;  2JC4 A;  3G3Y A;  4B5J A;  3DNI A;  2DDR A;  5INN A;  1BIX A;  4F1I A;  1SR4 B;  3FZI A;  2JC5 A;  2UYR X;  3W2X A;  5INM A;  4B5G A;  5INK A;  2A40 B;  1VYB A;  1DE9 A;  5DV4 A;  4GZ1 A;  4LND A;  2D1K B;  3I5V A;  2ISI A;  3G2C A;  1ATN D;  1HD7 A;  4B5M A;  4JG3 A;  4B5H A;  4QHD A;  3G0R A;  1DE8 A;  3GA6 A;  3G00 A;  3I41 A;  3I46 A;  4GEW A;  2EI9 A;  4QHE A;  3G38 A;  3K55 A;  4PUQ A;  2A42 B;  3NR8 A;  5EWT A;  3MTC A;  1I9Y A;  3I48 A;  3NGQ A;  3G2D A;  2F2F B;  3L1W A;  4QH9 A;  5CFG A;  4RUW A;  3TEB A;  2A3Z B;  5DG0 A;  2O3H A;  5INQ A;  3N9V A;  5INP A;  1E9N A;  5DV2 A;  3G4T A;  1AKO A;  1I9Z A;  1NTF A;  3G0A A;  5DFH A;  4IEM A;  3MPR A;  5HT2 A;  3G3C A;  4L21 A;  3U8U A;  5J42 A;  5DFF A;  2J63 A;  4FVA A;  1ZWX A;  4L20 A;  2IMQ X;  1DNK A;  2A41 B;  2XSW A;  1SI6 X;  1YJH A;  4A9C A;  4L1Y A;  5INO A;  4B5F A;  4B5I A;  4F1R A;  4L1Z A;  3NGN A;  4GZ2 A;  2DDT A;  4CML A;  2VOA A;  4GYZ A;  3G1K A;  5J3S A;  3G8V A;  4F1H A;  2V0R A;  5A7I A;  4CMN A;  3G6S A;  5DFJ A;  3G91 A;  5INL A;  1Y21 A;  2DNJ A;  2DDS A;  3WCX A;  4AWN A;  5J3Z A;  3CJC D;  3W2Y A;  4C1R A; 
#chains in the Genus database with same CATH homology
 5J8N A;  4FPV A;  2F1N A;  2O3C A;  4F1H B;  1DEW A;  3NGO A;  5A7J A;  4GZ0 A;  5DFI A;  5J3P A;  5CFE A;  3W3D B;  4K6L F;  1WDU A;  2V0S A;  2JC4 A;  3G3Y A;  4B5J A;  3DNI A;  2DDR A;  5INN A;  1BIX A;  4F1I A;  1SR4 B;  3FZI A;  2JC5 A;  2UYR X;  3W2X A;  5INM A;  4B5G A;  5INK A;  2A40 B;  1VYB A;  1DE9 A;  5DV4 A;  4GZ1 A;  4LND A;  2D1K B;  3I5V A;  2ISI A;  3G2C A;  1ATN D;  1HD7 A;  4B5M A;  4JG3 A;  4B5H A;  4QHD A;  3G0R A;  1DE8 A;  3GA6 A;  3G00 A;  3I41 A;  3I46 A;  4GEW A;  2EI9 A;  4QHE A;  3G38 A;  3K55 A;  4PUQ A;  2A42 B;  3NR8 A;  5EWT A;  3MTC A;  1I9Y A;  3I48 A;  3NGQ A;  3G2D A;  2F2F B;  3L1W A;  4QH9 A;  5CFG A;  4RUW A;  3TEB A;  2A3Z B;  5DG0 A;  2O3H A;  5INQ A;  3N9V A;  5INP A;  1E9N A;  5DV2 A;  3G4T A;  1AKO A;  1I9Z A;  1NTF A;  3G0A A;  5DFH A;  4IEM A;  3MPR A;  5HT2 A;  3G3C A;  4L21 A;  3U8U A;  5J42 A;  5DFF A;  2J63 A;  4FVA A;  1ZWX A;  4L20 A;  2IMQ X;  1DNK A;  2A41 B;  2XSW A;  1SI6 X;  1YJH A;  4A9C A;  4L1Y A;  5INO A;  4B5F A;  4B5I A;  4F1R A;  4L1Z A;  3NGN A;  4GZ2 A;  2DDT A;  4CML A;  2VOA A;  4GYZ A;  3G1K A;  5J3S A;  3G8V A;  4F1H A;  2V0R A;  5A7I A;  4CMN A;  3G6S A;  5DFJ A;  3G91 A;  5INL A;  1Y21 A;  2DNJ A;  2DDS A;  3WCX A;  4AWN A;  5J3Z A;  3CJC D;  3W2Y A;  4C1R A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...