3GA6A

Mth0212 in complex with two dna helices
Total Genus 83
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
83
sequence length
254
structure length
254
Chain Sequence
VLKIISWNVNGLRAVHRKGFLKWFMEEKPDILCLQEIKAAPEQLPRKLRHVEGYRSFFTPAERKGYSGVAMYTKVPPSSLREGFGVERFDTEGRIQIADFDDFLLYNIYFPNGKMSEERLKYKLEFYDAFLEDVNRERDSGRNVIICGNFNTAHREIDLARPKENSNVSGFLPVERAWIDKFIENGYVDTFRMFNSDPGQYTWWSYRTRARERNVGWRLDYFFVNEEFKGKVKRSWILSDVMGSDHCPIGLEIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal Structure Analysis of DNA Uridine Endonuclease Mth212 Bound to DNA
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Methanothermobacter thermautotrophicus
molecule keywords Exodeoxyribonuclease
total genus 83
structure length 254
sequence length 254
chains with identical sequence B
ec nomenclature ec 3.1.11.2: Exodeoxyribonuclease III.
pdb deposition date 2009-02-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 3ga6A00
2J63A 5DFFA 4GZ2A 2A3ZB 4FPVA 3G0AA 5DG0A 1YJHA 4RUWA 3G2CA 1BIXA 4F1IA 4GZ0A 1DEWA 4C1RA 3G91A 5EWTA 4A9CA 2O3HA 2XSWA 4QHDA 4GZ1A 3CJCD 3FZIA 4L21A 3NGNA 4LNDA 5J42A 3G00A 4B5HA 3G3YA 3G2DA 2DDTA 3G0RA 4CMNA 1ATND 4K6LF 4CMLA 4GYZA 2A41B 3I5VA 3W2YA 4FVAA 1ZWXA 5A7IA 5DV2A 5DFHA 4B5MA 3W3DB 5INKA 1DNKA 3MTCA 4L1ZA 3K55A 3L1WA 1DE8A 2JC5A 4PUQA 4B5JA 2DDSA 5DFJA 3I41A 3N9VA 3DNIA 4GEWA 4QH9A 2DDRA 1SI6X 3NGQA 2V0SA 5J3ZA 5J3SA 3G1KA 3NR8A 5CFEA 2O3CA 5DV4A 1NTFA 1I9ZA 5INQA 4L20A 3GA6A 2F2FB 2F1NA 3G38A 5INNA 5INMA 4F1RA 5HT2A 4B5GA 4QHEA 3G8VA 1DE9A 3G3CA 5INLA 2ISIA 2IMQX 3W2XA 4B5IA 5DFIA 2V0RA 5CFGA 1AKOA 3NGOA 3U8UA 1WDUA 2EI9A 3G6SA 4L1YA 1VYBA 4AWNA 2D1KB 4IEMA 2DNJA 2A42B 3TEBA 1E9NA 5INPA 4F1HB 1Y21A 1I9YA 2UYRX 4JG3A 2A40B 4F1HA 4B5FA 5J3PA 3I48A 5J8NA 2VOAA 3I46A 1SR4B 3MPRA 2JC4A 5INOA 5A7JA 3G4TA 1HD7A 3WCXA
chains in the Genus database with same CATH superfamily
2J63A 5DFFA 4GZ2A 2A3ZB 4FPVA 3G0AA 5DG0A 1YJHA 4RUWA 3G2CA 1BIXA 4F1IA 4GZ0A 1DEWA 4C1RA 3G91A 5EWTA 4A9CA 2O3HA 2XSWA 4QHDA 4GZ1A 3CJCD 3FZIA 4L21A 3NGNA 4LNDA 5J42A 3G00A 4B5HA 3G3YA 3G2DA 2DDTA 3G0RA 4CMNA 1ATND 4K6LF 4CMLA 4GYZA 2A41B 3I5VA 3W2YA 4FVAA 1ZWXA 5A7IA 5DV2A 5DFHA 4B5MA 3W3DB 5INKA 1DNKA 3MTCA 4L1ZA 3K55A 3L1WA 1DE8A 2JC5A 4PUQA 4B5JA 2DDSA 5DFJA 3I41A 3N9VA 3DNIA 4GEWA 4QH9A 2DDRA 1SI6X 3NGQA 2V0SA 5J3ZA 5J3SA 3G1KA 3NR8A 5CFEA 2O3CA 5DV4A 1NTFA 1I9ZA 5INQA 4L20A 3GA6A 2F2FB 2F1NA 3G38A 5INNA 5INMA 4F1RA 5HT2A 4B5GA 4QHEA 3G8VA 1DE9A 3G3CA 5INLA 2ISIA 2IMQX 3W2XA 4B5IA 5DFIA 2V0RA 5CFGA 1AKOA 3NGOA 3U8UA 1WDUA 2EI9A 3G6SA 4L1YA 1VYBA 4AWNA 2D1KB 4IEMA 2DNJA 2A42B 3TEBA 1E9NA 5INPA 4F1HB 1Y21A 1I9YA 2UYRX 4JG3A 2A40B 4F1HA 4B5FA 5J3PA 3I48A 5J8NA 2VOAA 3I46A 1SR4B 3MPRA 2JC4A 5INOA 5A7JA 3G4TA 1HD7A 3WCXA
chains in the Genus database with same CATH topology
2J63A 5DFFA 4GZ2A 2A3ZB 4FPVA 3G0AA 5DG0A 1YJHA 4RUWA 3G2CA 1BIXA 4F1IA 4GZ0A 1DEWA 4C1RA 3G91A 5EWTA 4A9CA 2O3HA 2XSWA 4QHDA 4GZ1A 3CJCD 3FZIA 4L21A 3NGNA 4LNDA 5J42A 3G00A 4B5HA 3G3YA 3G2DA 2DDTA 3G0RA 4CMNA 1ATND 4K6LF 4CMLA 4GYZA 2A41B 3I5VA 3W2YA 4FVAA 1ZWXA 5A7IA 5DV2A 5DFHA 4B5MA 3W3DB 5INKA 1DNKA 3MTCA 4L1ZA 3K55A 3L1WA 1DE8A 2JC5A 4PUQA 4B5JA 2DDSA 5DFJA 3I41A 3N9VA 3DNIA 4GEWA 4QH9A 2DDRA 1SI6X 3NGQA 2V0SA 5J3ZA 5J3SA 3G1KA 3NR8A 5CFEA 2O3CA 5DV4A 1NTFA 1I9ZA 5INQA 4L20A 3GA6A 2F2FB 2F1NA 3G38A 5INNA 5INMA 4F1RA 5HT2A 4B5GA 4QHEA 3G8VA 1DE9A 3G3CA 5INLA 2ISIA 2IMQX 3W2XA 4B5IA 5DFIA 2V0RA 5CFGA 1AKOA 3NGOA 3U8UA 1WDUA 2EI9A 3G6SA 4L1YA 1VYBA 4AWNA 2D1KB 4IEMA 2DNJA 2A42B 3TEBA 1E9NA 5INPA 4F1HB 1Y21A 1I9YA 2UYRX 4JG3A 2A40B 4F1HA 4B5FA 5J3PA 3I48A 5J8NA 2VOAA 3I46A 1SR4B 3MPRA 2JC4A 5INOA 5A7JA 3G4TA 1HD7A 3WCXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2J63 A;  5DFF A;  4GZ2 A;  2A3Z B;  4FPV A;  3G0A A;  5DG0 A;  1YJH A;  4RUW A;  3G2C A;  1BIX A;  4F1I A;  4GZ0 A;  1DEW A;  4C1R A;  3G91 A;  5EWT A;  4A9C A;  2O3H A;  2XSW A;  4QHD A;  4GZ1 A;  3CJC D;  3FZI A;  4L21 A;  3NGN A;  4LND A;  5J42 A;  3G00 A;  4B5H A;  3G3Y A;  3G2D A;  2DDT A;  3G0R A;  4CMN A;  1ATN D;  4K6L F;  4CML A;  4GYZ A;  2A41 B;  3I5V A;  3W2Y A;  4FVA A;  1ZWX A;  5A7I A;  5DV2 A;  5DFH A;  4B5M A;  3W3D B;  5INK A;  1DNK A;  3MTC A;  4L1Z A;  3K55 A;  3L1W A;  1DE8 A;  2JC5 A;  4PUQ A;  4B5J A;  2DDS A;  5DFJ A;  3I41 A;  3N9V A;  3DNI A;  4GEW A;  4QH9 A;  2DDR A;  1SI6 X;  3NGQ A;  2V0S A;  5J3Z A;  5J3S A;  3G1K A;  3NR8 A;  5CFE A;  2O3C A;  5DV4 A;  1NTF A;  1I9Z A;  5INQ A;  4L20 A;  3GA6 A;  2F2F B;  2F1N A;  3G38 A;  5INN A;  5INM A;  4F1R A;  5HT2 A;  4B5G A;  4QHE A;  3G8V A;  1DE9 A;  3G3C A;  5INL A;  2ISI A;  2IMQ X;  3W2X A;  4B5I A;  5DFI A;  2V0R A;  5CFG A;  1AKO A;  3NGO A;  3U8U A;  1WDU A;  2EI9 A;  3G6S A;  4L1Y A;  1VYB A;  4AWN A;  2D1K B;  4IEM A;  2DNJ A;  2A42 B;  3TEB A;  1E9N A;  5INP A;  4F1H B;  1Y21 A;  1I9Y A;  2UYR X;  4JG3 A;  2A40 B;  4F1H A;  4B5F A;  5J3P A;  3I48 A;  5J8N A;  2VOA A;  3I46 A;  1SR4 B;  3MPR A;  2JC4 A;  5INO A;  5A7J A;  3G4T A;  1HD7 A;  3WCX A; 
#chains in the Genus database with same CATH topology
 2J63 A;  5DFF A;  4GZ2 A;  2A3Z B;  4FPV A;  3G0A A;  5DG0 A;  1YJH A;  4RUW A;  3G2C A;  1BIX A;  4F1I A;  4GZ0 A;  1DEW A;  4C1R A;  3G91 A;  5EWT A;  4A9C A;  2O3H A;  2XSW A;  4QHD A;  4GZ1 A;  3CJC D;  3FZI A;  4L21 A;  3NGN A;  4LND A;  5J42 A;  3G00 A;  4B5H A;  3G3Y A;  3G2D A;  2DDT A;  3G0R A;  4CMN A;  1ATN D;  4K6L F;  4CML A;  4GYZ A;  2A41 B;  3I5V A;  3W2Y A;  4FVA A;  1ZWX A;  5A7I A;  5DV2 A;  5DFH A;  4B5M A;  3W3D B;  5INK A;  1DNK A;  3MTC A;  4L1Z A;  3K55 A;  3L1W A;  1DE8 A;  2JC5 A;  4PUQ A;  4B5J A;  2DDS A;  5DFJ A;  3I41 A;  3N9V A;  3DNI A;  4GEW A;  4QH9 A;  2DDR A;  1SI6 X;  3NGQ A;  2V0S A;  5J3Z A;  5J3S A;  3G1K A;  3NR8 A;  5CFE A;  2O3C A;  5DV4 A;  1NTF A;  1I9Z A;  5INQ A;  4L20 A;  3GA6 A;  2F2F B;  2F1N A;  3G38 A;  5INN A;  5INM A;  4F1R A;  5HT2 A;  4B5G A;  4QHE A;  3G8V A;  1DE9 A;  3G3C A;  5INL A;  2ISI A;  2IMQ X;  3W2X A;  4B5I A;  5DFI A;  2V0R A;  5CFG A;  1AKO A;  3NGO A;  3U8U A;  1WDU A;  2EI9 A;  3G6S A;  4L1Y A;  1VYB A;  4AWN A;  2D1K B;  4IEM A;  2DNJ A;  2A42 B;  3TEB A;  1E9N A;  5INP A;  4F1H B;  1Y21 A;  1I9Y A;  2UYR X;  4JG3 A;  2A40 B;  4F1H A;  4B5F A;  5J3P A;  3I48 A;  5J8N A;  2VOA A;  3I46 A;  1SR4 B;  3MPR A;  2JC4 A;  5INO A;  5A7J A;  3G4T A;  1HD7 A;  3WCX A; 
#chains in the Genus database with same CATH homology
 2J63 A;  5DFF A;  4GZ2 A;  2A3Z B;  4FPV A;  3G0A A;  5DG0 A;  1YJH A;  4RUW A;  3G2C A;  1BIX A;  4F1I A;  4GZ0 A;  1DEW A;  4C1R A;  3G91 A;  5EWT A;  4A9C A;  2O3H A;  2XSW A;  4QHD A;  4GZ1 A;  3CJC D;  3FZI A;  4L21 A;  3NGN A;  4LND A;  5J42 A;  3G00 A;  4B5H A;  3G3Y A;  3G2D A;  2DDT A;  3G0R A;  4CMN A;  1ATN D;  4K6L F;  4CML A;  4GYZ A;  2A41 B;  3I5V A;  3W2Y A;  4FVA A;  1ZWX A;  5A7I A;  5DV2 A;  5DFH A;  4B5M A;  3W3D B;  5INK A;  1DNK A;  3MTC A;  4L1Z A;  3K55 A;  3L1W A;  1DE8 A;  2JC5 A;  4PUQ A;  4B5J A;  2DDS A;  5DFJ A;  3I41 A;  3N9V A;  3DNI A;  4GEW A;  4QH9 A;  2DDR A;  1SI6 X;  3NGQ A;  2V0S A;  5J3Z A;  5J3S A;  3G1K A;  3NR8 A;  5CFE A;  2O3C A;  5DV4 A;  1NTF A;  1I9Z A;  5INQ A;  4L20 A;  3GA6 A;  2F2F B;  2F1N A;  3G38 A;  5INN A;  5INM A;  4F1R A;  5HT2 A;  4B5G A;  4QHE A;  3G8V A;  1DE9 A;  3G3C A;  5INL A;  2ISI A;  2IMQ X;  3W2X A;  4B5I A;  5DFI A;  2V0R A;  5CFG A;  1AKO A;  3NGO A;  3U8U A;  1WDU A;  2EI9 A;  3G6S A;  4L1Y A;  1VYB A;  4AWN A;  2D1K B;  4IEM A;  2DNJ A;  2A42 B;  3TEB A;  1E9N A;  5INP A;  4F1H B;  1Y21 A;  1I9Y A;  2UYR X;  4JG3 A;  2A40 B;  4F1H A;  4B5F A;  5J3P A;  3I48 A;  5J8N A;  2VOA A;  3I46 A;  1SR4 B;  3MPR A;  2JC4 A;  5INO A;  5A7J A;  3G4T A;  1HD7 A;  3WCX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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