2DDRA

Crystal structure of sphingomyelinase from bacillus cereus with calcium ion
Total Genus 94
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
299
structure length
288
Chain Sequence
NDTLKVMTHNVYMLSTNLYPNWGQTERADLIGAADYIKNQDVVILNEVFDNSASDRLLGNLKKEYPNQTAVLGRSSGSEWDKTLGNYSSSTPEDGGVAIVSKWPIAEKIQYVFAKGCLSNKGFVYTKIKKNDRFVHVIGTHLQAESPASVRTNQLKEIQDFIKNKNIPNNEYVLIGGDMNVNKINAENNNDSEYASMFKTLNASVPSYTGHTATWDATTNSIAKYNFPDSPAEYLDYIIASKDHANPSYIENKVLQPKSPQWTVTSWFQKYTYNDYSDHYPVEATISM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural Basis of the Sphingomyelin Phosphodiesterase Activity in Neutral Sphingomyelinase from Bacillus cereus.
pubmed doi rcsb
molecule tags Hydrolase
source organism Bacillus cereus
molecule keywords Sphingomyelin phosphodiesterase
total genus 94
structure length 288
sequence length 299
chains with identical sequence B, C, D
ec nomenclature ec 3.1.4.12: Sphingomyelin phosphodiesterase.
pdb deposition date 2006-02-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 2ddrA00
3GA6A 2O3CA 4GZ1A 1DEWA 4QH9A 3G8VA 2EI9A 4GZ2A 3W2XA 3NGQA 3G0RA 1SR4B 2JC4A 5INOA 3TEBA 1VYBA 4GYZA 4L1ZA 3N9VA 4RUWA 4L21A 4GEWA 3I48A 3G00A 3NR8A 2A41B 4B5MA 2A42B 3G2DA 3I46A 2JC5A 5DFFA 2A3ZB 4L20A 3MTCA 2F2FB 2IMQX 4F1IA 5J42A 5J8NA 5HT2A 1NTFA 3NGNA 2A40B 5INMA 1AKOA 2O3HA 1DE9A 1I9YA 4F1HA 1SI6X 4CMNA 5INLA 2XSWA 3MPRA 3G0AA 3WCXA 4QHEA 5J3ZA 5J3SA 5A7JA 1ATND 3I5VA 3DNIA 1HD7A 3G2CA 2V0SA 1YJHA 5CFGA 3U8UA 5INQA 2D1KB 5DV2A 1DNKA 2J63A 4F1HB 4K6LF 4IEMA 1E9NA 5A7IA 2DDTA 4QHDA 4F1RA 3K55A 3G6SA 4L1YA 3L1WA 1ZWXA 4JG3A 4B5IA 5DG0A 5INPA 3I41A 4C1RA 2V0RA 3FZIA 4B5GA 1Y21A 3NGOA 3G3CA 3G1KA 3CJCD 4FVAA 5EWTA 3W3DB 5DFJA 4CMLA 3G38A 5INNA 3G91A 2ISIA 4LNDA 5CFEA 4B5JA 5DV4A 4A9CA 2UYRX 3G4TA 4B5FA 2DDSA 2DDRA 4PUQA 4AWNA 1DE8A 4B5HA 5INKA 1I9ZA 1WDUA 5J3PA 4FPVA 1BIXA 2VOAA 2DNJA 4GZ0A 3G3YA 5DFIA 2F1NA 3W2YA 5DFHA
chains in the Genus database with same CATH superfamily
3GA6A 2O3CA 4GZ1A 1DEWA 4QH9A 3G8VA 2EI9A 4GZ2A 3W2XA 3NGQA 3G0RA 1SR4B 2JC4A 5INOA 3TEBA 1VYBA 4GYZA 4L1ZA 3N9VA 4RUWA 4L21A 4GEWA 3I48A 3G00A 3NR8A 2A41B 4B5MA 2A42B 3G2DA 3I46A 2JC5A 5DFFA 2A3ZB 4L20A 3MTCA 2F2FB 2IMQX 4F1IA 5J42A 5J8NA 5HT2A 1NTFA 3NGNA 2A40B 5INMA 1AKOA 2O3HA 1DE9A 1I9YA 4F1HA 1SI6X 4CMNA 5INLA 2XSWA 3MPRA 3G0AA 3WCXA 4QHEA 5J3ZA 5J3SA 5A7JA 1ATND 3I5VA 3DNIA 1HD7A 3G2CA 2V0SA 1YJHA 5CFGA 3U8UA 5INQA 2D1KB 5DV2A 1DNKA 2J63A 4F1HB 4K6LF 4IEMA 1E9NA 5A7IA 2DDTA 4QHDA 4F1RA 3K55A 3G6SA 4L1YA 3L1WA 1ZWXA 4JG3A 4B5IA 5DG0A 5INPA 3I41A 4C1RA 2V0RA 3FZIA 4B5GA 1Y21A 3NGOA 3G3CA 3G1KA 3CJCD 4FVAA 5EWTA 3W3DB 5DFJA 4CMLA 3G38A 5INNA 3G91A 2ISIA 4LNDA 5CFEA 4B5JA 5DV4A 4A9CA 2UYRX 3G4TA 4B5FA 2DDSA 2DDRA 4PUQA 4AWNA 1DE8A 4B5HA 5INKA 1I9ZA 1WDUA 5J3PA 4FPVA 1BIXA 2VOAA 2DNJA 4GZ0A 3G3YA 5DFIA 2F1NA 3W2YA 5DFHA
chains in the Genus database with same CATH topology
3GA6A 2O3CA 4GZ1A 1DEWA 4QH9A 3G8VA 2EI9A 4GZ2A 3W2XA 3NGQA 3G0RA 1SR4B 2JC4A 5INOA 3TEBA 1VYBA 4GYZA 4L1ZA 3N9VA 4RUWA 4L21A 4GEWA 3I48A 3G00A 3NR8A 2A41B 4B5MA 2A42B 3G2DA 3I46A 2JC5A 5DFFA 2A3ZB 4L20A 3MTCA 2F2FB 2IMQX 4F1IA 5J42A 5J8NA 5HT2A 1NTFA 3NGNA 2A40B 5INMA 1AKOA 2O3HA 1DE9A 1I9YA 4F1HA 1SI6X 4CMNA 5INLA 2XSWA 3MPRA 3G0AA 3WCXA 4QHEA 5J3ZA 5J3SA 5A7JA 1ATND 3I5VA 3DNIA 1HD7A 3G2CA 2V0SA 1YJHA 5CFGA 3U8UA 5INQA 2D1KB 5DV2A 1DNKA 2J63A 4F1HB 4K6LF 4IEMA 1E9NA 5A7IA 2DDTA 4QHDA 4F1RA 3K55A 3G6SA 4L1YA 3L1WA 1ZWXA 4JG3A 4B5IA 5DG0A 5INPA 3I41A 4C1RA 2V0RA 3FZIA 4B5GA 1Y21A 3NGOA 3G3CA 3G1KA 3CJCD 4FVAA 5EWTA 3W3DB 5DFJA 4CMLA 3G38A 5INNA 3G91A 2ISIA 4LNDA 5CFEA 4B5JA 5DV4A 4A9CA 2UYRX 3G4TA 4B5FA 2DDSA 2DDRA 4PUQA 4AWNA 1DE8A 4B5HA 5INKA 1I9ZA 1WDUA 5J3PA 4FPVA 1BIXA 2VOAA 2DNJA 4GZ0A 3G3YA 5DFIA 2F1NA 3W2YA 5DFHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GA6 A;  2O3C A;  4GZ1 A;  1DEW A;  4QH9 A;  3G8V A;  2EI9 A;  4GZ2 A;  3W2X A;  3NGQ A;  3G0R A;  1SR4 B;  2JC4 A;  5INO A;  3TEB A;  1VYB A;  4GYZ A;  4L1Z A;  3N9V A;  4RUW A;  4L21 A;  4GEW A;  3I48 A;  3G00 A;  3NR8 A;  2A41 B;  4B5M A;  2A42 B;  3G2D A;  3I46 A;  2JC5 A;  5DFF A;  2A3Z B;  4L20 A;  3MTC A;  2F2F B;  2IMQ X;  4F1I A;  5J42 A;  5J8N A;  5HT2 A;  1NTF A;  3NGN A;  2A40 B;  5INM A;  1AKO A;  2O3H A;  1DE9 A;  1I9Y A;  4F1H A;  1SI6 X;  4CMN A;  5INL A;  2XSW A;  3MPR A;  3G0A A;  3WCX A;  4QHE A;  5J3Z A;  5J3S A;  5A7J A;  1ATN D;  3I5V A;  3DNI A;  1HD7 A;  3G2C A;  2V0S A;  1YJH A;  5CFG A;  3U8U A;  5INQ A;  2D1K B;  5DV2 A;  1DNK A;  2J63 A;  4F1H B;  4K6L F;  4IEM A;  1E9N A;  5A7I A;  2DDT A;  4QHD A;  4F1R A;  3K55 A;  3G6S A;  4L1Y A;  3L1W A;  1ZWX A;  4JG3 A;  4B5I A;  5DG0 A;  5INP A;  3I41 A;  4C1R A;  2V0R A;  3FZI A;  4B5G A;  1Y21 A;  3NGO A;  3G3C A;  3G1K A;  3CJC D;  4FVA A;  5EWT A;  3W3D B;  5DFJ A;  4CML A;  3G38 A;  5INN A;  3G91 A;  2ISI A;  4LND A;  5CFE A;  4B5J A;  5DV4 A;  4A9C A;  2UYR X;  3G4T A;  4B5F A;  2DDS A;  2DDR A;  4PUQ A;  4AWN A;  1DE8 A;  4B5H A;  5INK A;  1I9Z A;  1WDU A;  5J3P A;  4FPV A;  1BIX A;  2VOA A;  2DNJ A;  4GZ0 A;  3G3Y A;  5DFI A;  2F1N A;  3W2Y A;  5DFH A; 
#chains in the Genus database with same CATH topology
 3GA6 A;  2O3C A;  4GZ1 A;  1DEW A;  4QH9 A;  3G8V A;  2EI9 A;  4GZ2 A;  3W2X A;  3NGQ A;  3G0R A;  1SR4 B;  2JC4 A;  5INO A;  3TEB A;  1VYB A;  4GYZ A;  4L1Z A;  3N9V A;  4RUW A;  4L21 A;  4GEW A;  3I48 A;  3G00 A;  3NR8 A;  2A41 B;  4B5M A;  2A42 B;  3G2D A;  3I46 A;  2JC5 A;  5DFF A;  2A3Z B;  4L20 A;  3MTC A;  2F2F B;  2IMQ X;  4F1I A;  5J42 A;  5J8N A;  5HT2 A;  1NTF A;  3NGN A;  2A40 B;  5INM A;  1AKO A;  2O3H A;  1DE9 A;  1I9Y A;  4F1H A;  1SI6 X;  4CMN A;  5INL A;  2XSW A;  3MPR A;  3G0A A;  3WCX A;  4QHE A;  5J3Z A;  5J3S A;  5A7J A;  1ATN D;  3I5V A;  3DNI A;  1HD7 A;  3G2C A;  2V0S A;  1YJH A;  5CFG A;  3U8U A;  5INQ A;  2D1K B;  5DV2 A;  1DNK A;  2J63 A;  4F1H B;  4K6L F;  4IEM A;  1E9N A;  5A7I A;  2DDT A;  4QHD A;  4F1R A;  3K55 A;  3G6S A;  4L1Y A;  3L1W A;  1ZWX A;  4JG3 A;  4B5I A;  5DG0 A;  5INP A;  3I41 A;  4C1R A;  2V0R A;  3FZI A;  4B5G A;  1Y21 A;  3NGO A;  3G3C A;  3G1K A;  3CJC D;  4FVA A;  5EWT A;  3W3D B;  5DFJ A;  4CML A;  3G38 A;  5INN A;  3G91 A;  2ISI A;  4LND A;  5CFE A;  4B5J A;  5DV4 A;  4A9C A;  2UYR X;  3G4T A;  4B5F A;  2DDS A;  2DDR A;  4PUQ A;  4AWN A;  1DE8 A;  4B5H A;  5INK A;  1I9Z A;  1WDU A;  5J3P A;  4FPV A;  1BIX A;  2VOA A;  2DNJ A;  4GZ0 A;  3G3Y A;  5DFI A;  2F1N A;  3W2Y A;  5DFH A; 
#chains in the Genus database with same CATH homology
 3GA6 A;  2O3C A;  4GZ1 A;  1DEW A;  4QH9 A;  3G8V A;  2EI9 A;  4GZ2 A;  3W2X A;  3NGQ A;  3G0R A;  1SR4 B;  2JC4 A;  5INO A;  3TEB A;  1VYB A;  4GYZ A;  4L1Z A;  3N9V A;  4RUW A;  4L21 A;  4GEW A;  3I48 A;  3G00 A;  3NR8 A;  2A41 B;  4B5M A;  2A42 B;  3G2D A;  3I46 A;  2JC5 A;  5DFF A;  2A3Z B;  4L20 A;  3MTC A;  2F2F B;  2IMQ X;  4F1I A;  5J42 A;  5J8N A;  5HT2 A;  1NTF A;  3NGN A;  2A40 B;  5INM A;  1AKO A;  2O3H A;  1DE9 A;  1I9Y A;  4F1H A;  1SI6 X;  4CMN A;  5INL A;  2XSW A;  3MPR A;  3G0A A;  3WCX A;  4QHE A;  5J3Z A;  5J3S A;  5A7J A;  1ATN D;  3I5V A;  3DNI A;  1HD7 A;  3G2C A;  2V0S A;  1YJH A;  5CFG A;  3U8U A;  5INQ A;  2D1K B;  5DV2 A;  1DNK A;  2J63 A;  4F1H B;  4K6L F;  4IEM A;  1E9N A;  5A7I A;  2DDT A;  4QHD A;  4F1R A;  3K55 A;  3G6S A;  4L1Y A;  3L1W A;  1ZWX A;  4JG3 A;  4B5I A;  5DG0 A;  5INP A;  3I41 A;  4C1R A;  2V0R A;  3FZI A;  4B5G A;  1Y21 A;  3NGO A;  3G3C A;  3G1K A;  3CJC D;  4FVA A;  5EWT A;  3W3D B;  5DFJ A;  4CML A;  3G38 A;  5INN A;  3G91 A;  2ISI A;  4LND A;  5CFE A;  4B5J A;  5DV4 A;  4A9C A;  2UYR X;  3G4T A;  4B5F A;  2DDS A;  2DDR A;  4PUQ A;  4AWN A;  1DE8 A;  4B5H A;  5INK A;  1I9Z A;  1WDU A;  5J3P A;  4FPV A;  1BIX A;  2VOA A;  2DNJ A;  4GZ0 A;  3G3Y A;  5DFI A;  2F1N A;  3W2Y A;  5DFH A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...