3WCXA

Crystal structure of sphingomyelinase c from streptomyces griseocarneus
Total Genus 99
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
292
structure length
291
Chain Sequence
TPSLKVLTYNTFLMSTGLYPNWGQEHRAREIAAAGFFQGNDVVVLQEAFDNAAADGLKAAAADRYPYQTPVVGRSRDGWDATGGKYSATTPEDGGVTVLSKWPIVRKEQVIFNDACGADWWSNKGFAYVVLNVGGTRVHVVGTHAQSTDSGCAAGEAAADRSRQFRQIDAFLDAKNIPADEQVMLAGDLNVDSHSAEYASMLADGDLAPADSRAGHPYSFDTKENSIAAYRYPTDPREDLDYVLHRNGHARPAGWRNTVVQETSAPWTVSSWKRYTYTDLSGHYPVIAGAN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Sphingomyelinase C from Streptomyces griseocarneus
rcsb
molecule tags Hydrolase
source organism Streptomyces griseocarneus
molecule keywords Sphingomyelinase C
total genus 99
structure length 291
sequence length 292
ec nomenclature ec 3.1.4.12: Sphingomyelin phosphodiesterase.
pdb deposition date 2013-06-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 3wcxA00
5J42A 3GA6A 4QHDA 4GZ2A 5A7IA 4L1YA 1Y21A 4PUQA 4JG3A 4F1HB 4C1RA 5J3ZA 3TEBA 4QH9A 3I5VA 5INOA 4GZ1A 3G38A 5A7JA 3I41A 2O3CA 1E9NA 2F2FB 4GZ0A 4B5IA 4RUWA 2A42B 5HT2A 4B5HA 2DNJA 1YJHA 1I9ZA 3G6SA 4LNDA 3NGOA 3I46A 4F1IA 4GEWA 5CFEA 4B5MA 3G1KA 2ISIA 4GYZA 1DEWA 5J3SA 2F1NA 1WDUA 2DDTA 3W2YA 5DFFA 3N9VA 5INPA 3G00A 3G0RA 2O3HA 3MPRA 4FPVA 5EWTA 4K6LF 3G3YA 2DDRA 2XSWA 2A40B 5DFHA 2UYRX 4A9CA 5J3PA 1DE8A 5DV2A 1ZWXA 3U8UA 1I9YA 3G0AA 5DFJA 4F1RA 2JC5A 5DG0A 5INNA 3CJCD 3WCXA 1SR4B 3MTCA 4QHEA 3DNIA 4B5JA 3NGQA 4FVAA 2A3ZB 4L20A 3FZIA 4L21A 3G4TA 2V0RA 3L1WA 5INMA 5CFGA 5INLA 3NR8A 4CMNA 5INKA 2V0SA 3G8VA 5INQA 5J8NA 1BIXA 3K55A 3G91A 3NGNA 3W3DB 1NTFA 3G2CA 1HD7A 1DE9A 2VOAA 5DFIA 4B5FA 3G3CA 2IMQX 3G2DA 4AWNA 4IEMA 4B5GA 2EI9A 2D1KB 2DDSA 4F1HA 1VYBA 4CMLA 3W2XA 2JC4A 4L1ZA 1SI6X 1AKOA 3I48A 2A41B 5DV4A 1DNKA 1ATND 2J63A
chains in the Genus database with same CATH superfamily
5J42A 3GA6A 4QHDA 4GZ2A 5A7IA 4L1YA 1Y21A 4PUQA 4JG3A 4F1HB 4C1RA 5J3ZA 3TEBA 4QH9A 3I5VA 5INOA 4GZ1A 3G38A 5A7JA 3I41A 2O3CA 1E9NA 2F2FB 4GZ0A 4B5IA 4RUWA 2A42B 5HT2A 4B5HA 2DNJA 1YJHA 1I9ZA 3G6SA 4LNDA 3NGOA 3I46A 4F1IA 4GEWA 5CFEA 4B5MA 3G1KA 2ISIA 4GYZA 1DEWA 5J3SA 2F1NA 1WDUA 2DDTA 3W2YA 5DFFA 3N9VA 5INPA 3G00A 3G0RA 2O3HA 3MPRA 4FPVA 5EWTA 4K6LF 3G3YA 2DDRA 2XSWA 2A40B 5DFHA 2UYRX 4A9CA 5J3PA 1DE8A 5DV2A 1ZWXA 3U8UA 1I9YA 3G0AA 5DFJA 4F1RA 2JC5A 5DG0A 5INNA 3CJCD 3WCXA 1SR4B 3MTCA 4QHEA 3DNIA 4B5JA 3NGQA 4FVAA 2A3ZB 4L20A 3FZIA 4L21A 3G4TA 2V0RA 3L1WA 5INMA 5CFGA 5INLA 3NR8A 4CMNA 5INKA 2V0SA 3G8VA 5INQA 5J8NA 1BIXA 3K55A 3G91A 3NGNA 3W3DB 1NTFA 3G2CA 1HD7A 1DE9A 2VOAA 5DFIA 4B5FA 3G3CA 2IMQX 3G2DA 4AWNA 4IEMA 4B5GA 2EI9A 2D1KB 2DDSA 4F1HA 1VYBA 4CMLA 3W2XA 2JC4A 4L1ZA 1SI6X 1AKOA 3I48A 2A41B 5DV4A 1DNKA 1ATND 2J63A
chains in the Genus database with same CATH topology
5J42A 3GA6A 4QHDA 4GZ2A 5A7IA 4L1YA 1Y21A 4PUQA 4JG3A 4F1HB 4C1RA 5J3ZA 3TEBA 4QH9A 3I5VA 5INOA 4GZ1A 3G38A 5A7JA 3I41A 2O3CA 1E9NA 2F2FB 4GZ0A 4B5IA 4RUWA 2A42B 5HT2A 4B5HA 2DNJA 1YJHA 1I9ZA 3G6SA 4LNDA 3NGOA 3I46A 4F1IA 4GEWA 5CFEA 4B5MA 3G1KA 2ISIA 4GYZA 1DEWA 5J3SA 2F1NA 1WDUA 2DDTA 3W2YA 5DFFA 3N9VA 5INPA 3G00A 3G0RA 2O3HA 3MPRA 4FPVA 5EWTA 4K6LF 3G3YA 2DDRA 2XSWA 2A40B 5DFHA 2UYRX 4A9CA 5J3PA 1DE8A 5DV2A 1ZWXA 3U8UA 1I9YA 3G0AA 5DFJA 4F1RA 2JC5A 5DG0A 5INNA 3CJCD 3WCXA 1SR4B 3MTCA 4QHEA 3DNIA 4B5JA 3NGQA 4FVAA 2A3ZB 4L20A 3FZIA 4L21A 3G4TA 2V0RA 3L1WA 5INMA 5CFGA 5INLA 3NR8A 4CMNA 5INKA 2V0SA 3G8VA 5INQA 5J8NA 1BIXA 3K55A 3G91A 3NGNA 3W3DB 1NTFA 3G2CA 1HD7A 1DE9A 2VOAA 5DFIA 4B5FA 3G3CA 2IMQX 3G2DA 4AWNA 4IEMA 4B5GA 2EI9A 2D1KB 2DDSA 4F1HA 1VYBA 4CMLA 3W2XA 2JC4A 4L1ZA 1SI6X 1AKOA 3I48A 2A41B 5DV4A 1DNKA 1ATND 2J63A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5J42 A;  3GA6 A;  4QHD A;  4GZ2 A;  5A7I A;  4L1Y A;  1Y21 A;  4PUQ A;  4JG3 A;  4F1H B;  4C1R A;  5J3Z A;  3TEB A;  4QH9 A;  3I5V A;  5INO A;  4GZ1 A;  3G38 A;  5A7J A;  3I41 A;  2O3C A;  1E9N A;  2F2F B;  4GZ0 A;  4B5I A;  4RUW A;  2A42 B;  5HT2 A;  4B5H A;  2DNJ A;  1YJH A;  1I9Z A;  3G6S A;  4LND A;  3NGO A;  3I46 A;  4F1I A;  4GEW A;  5CFE A;  4B5M A;  3G1K A;  2ISI A;  4GYZ A;  1DEW A;  5J3S A;  2F1N A;  1WDU A;  2DDT A;  3W2Y A;  5DFF A;  3N9V A;  5INP A;  3G00 A;  3G0R A;  2O3H A;  3MPR A;  4FPV A;  5EWT A;  4K6L F;  3G3Y A;  2DDR A;  2XSW A;  2A40 B;  5DFH A;  2UYR X;  4A9C A;  5J3P A;  1DE8 A;  5DV2 A;  1ZWX A;  3U8U A;  1I9Y A;  3G0A A;  5DFJ A;  4F1R A;  2JC5 A;  5DG0 A;  5INN A;  3CJC D;  3WCX A;  1SR4 B;  3MTC A;  4QHE A;  3DNI A;  4B5J A;  3NGQ A;  4FVA A;  2A3Z B;  4L20 A;  3FZI A;  4L21 A;  3G4T A;  2V0R A;  3L1W A;  5INM A;  5CFG A;  5INL A;  3NR8 A;  4CMN A;  5INK A;  2V0S A;  3G8V A;  5INQ A;  5J8N A;  1BIX A;  3K55 A;  3G91 A;  3NGN A;  3W3D B;  1NTF A;  3G2C A;  1HD7 A;  1DE9 A;  2VOA A;  5DFI A;  4B5F A;  3G3C A;  2IMQ X;  3G2D A;  4AWN A;  4IEM A;  4B5G A;  2EI9 A;  2D1K B;  2DDS A;  4F1H A;  1VYB A;  4CML A;  3W2X A;  2JC4 A;  4L1Z A;  1SI6 X;  1AKO A;  3I48 A;  2A41 B;  5DV4 A;  1DNK A;  1ATN D;  2J63 A; 
#chains in the Genus database with same CATH topology
 5J42 A;  3GA6 A;  4QHD A;  4GZ2 A;  5A7I A;  4L1Y A;  1Y21 A;  4PUQ A;  4JG3 A;  4F1H B;  4C1R A;  5J3Z A;  3TEB A;  4QH9 A;  3I5V A;  5INO A;  4GZ1 A;  3G38 A;  5A7J A;  3I41 A;  2O3C A;  1E9N A;  2F2F B;  4GZ0 A;  4B5I A;  4RUW A;  2A42 B;  5HT2 A;  4B5H A;  2DNJ A;  1YJH A;  1I9Z A;  3G6S A;  4LND A;  3NGO A;  3I46 A;  4F1I A;  4GEW A;  5CFE A;  4B5M A;  3G1K A;  2ISI A;  4GYZ A;  1DEW A;  5J3S A;  2F1N A;  1WDU A;  2DDT A;  3W2Y A;  5DFF A;  3N9V A;  5INP A;  3G00 A;  3G0R A;  2O3H A;  3MPR A;  4FPV A;  5EWT A;  4K6L F;  3G3Y A;  2DDR A;  2XSW A;  2A40 B;  5DFH A;  2UYR X;  4A9C A;  5J3P A;  1DE8 A;  5DV2 A;  1ZWX A;  3U8U A;  1I9Y A;  3G0A A;  5DFJ A;  4F1R A;  2JC5 A;  5DG0 A;  5INN A;  3CJC D;  3WCX A;  1SR4 B;  3MTC A;  4QHE A;  3DNI A;  4B5J A;  3NGQ A;  4FVA A;  2A3Z B;  4L20 A;  3FZI A;  4L21 A;  3G4T A;  2V0R A;  3L1W A;  5INM A;  5CFG A;  5INL A;  3NR8 A;  4CMN A;  5INK A;  2V0S A;  3G8V A;  5INQ A;  5J8N A;  1BIX A;  3K55 A;  3G91 A;  3NGN A;  3W3D B;  1NTF A;  3G2C A;  1HD7 A;  1DE9 A;  2VOA A;  5DFI A;  4B5F A;  3G3C A;  2IMQ X;  3G2D A;  4AWN A;  4IEM A;  4B5G A;  2EI9 A;  2D1K B;  2DDS A;  4F1H A;  1VYB A;  4CML A;  3W2X A;  2JC4 A;  4L1Z A;  1SI6 X;  1AKO A;  3I48 A;  2A41 B;  5DV4 A;  1DNK A;  1ATN D;  2J63 A; 
#chains in the Genus database with same CATH homology
 5J42 A;  3GA6 A;  4QHD A;  4GZ2 A;  5A7I A;  4L1Y A;  1Y21 A;  4PUQ A;  4JG3 A;  4F1H B;  4C1R A;  5J3Z A;  3TEB A;  4QH9 A;  3I5V A;  5INO A;  4GZ1 A;  3G38 A;  5A7J A;  3I41 A;  2O3C A;  1E9N A;  2F2F B;  4GZ0 A;  4B5I A;  4RUW A;  2A42 B;  5HT2 A;  4B5H A;  2DNJ A;  1YJH A;  1I9Z A;  3G6S A;  4LND A;  3NGO A;  3I46 A;  4F1I A;  4GEW A;  5CFE A;  4B5M A;  3G1K A;  2ISI A;  4GYZ A;  1DEW A;  5J3S A;  2F1N A;  1WDU A;  2DDT A;  3W2Y A;  5DFF A;  3N9V A;  5INP A;  3G00 A;  3G0R A;  2O3H A;  3MPR A;  4FPV A;  5EWT A;  4K6L F;  3G3Y A;  2DDR A;  2XSW A;  2A40 B;  5DFH A;  2UYR X;  4A9C A;  5J3P A;  1DE8 A;  5DV2 A;  1ZWX A;  3U8U A;  1I9Y A;  3G0A A;  5DFJ A;  4F1R A;  2JC5 A;  5DG0 A;  5INN A;  3CJC D;  3WCX A;  1SR4 B;  3MTC A;  4QHE A;  3DNI A;  4B5J A;  3NGQ A;  4FVA A;  2A3Z B;  4L20 A;  3FZI A;  4L21 A;  3G4T A;  2V0R A;  3L1W A;  5INM A;  5CFG A;  5INL A;  3NR8 A;  4CMN A;  5INK A;  2V0S A;  3G8V A;  5INQ A;  5J8N A;  1BIX A;  3K55 A;  3G91 A;  3NGN A;  3W3D B;  1NTF A;  3G2C A;  1HD7 A;  1DE9 A;  2VOA A;  5DFI A;  4B5F A;  3G3C A;  2IMQ X;  3G2D A;  4AWN A;  4IEM A;  4B5G A;  2EI9 A;  2D1K B;  2DDS A;  4F1H A;  1VYB A;  4CML A;  3W2X A;  2JC4 A;  4L1Z A;  1SI6 X;  1AKO A;  3I48 A;  2A41 B;  5DV4 A;  1DNK A;  1ATN D;  2J63 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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