1I9ZA

Crystal structure of inositol polyphosphate 5-phosphatase domain (ipp5c) of spsynaptojanin in complex with inositol (1,4)-bisphosphate and calcium ion
Total Genus 114
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
114
sequence length
345
structure length
336
Chain Sequence
YDPIHEYVNHELRKRENEFSEHKNVKIFVASYNLNGCSATTKLENWLFPENTPLADIYVVGFQEIVQLTSADPAKRREWESCVKRLLNGKCTSGPGYVQLRSGQLVGTALMIFCKESCLPSIKNVEGTVKKTGLGNKGAVAIRFDYEDTGLCFITSHLAAGYTNYDERDHDYRTIASGLRFRRGRSIFNHDYVVWFGDFNYRISLTYEEVVPCIAQGKLSYLFEYDQLNKQMLTGKVFPFFSELPITFPPTYKFDIGTDIYDTSDKHRVPAWTDRILYRGELVPHSYQSVPLYYSDHRPIYATYEANIVKVDREKKKILFEELYNQRKQEVRDASQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Specificity determinants in phosphoinositide dephosphorylation: crystal structure of an archetypal inositol polyphosphate 5-phosphatase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Schizosaccharomyces pombe
molecule keywords PHOSPHATIDYLINOSITOL PHOSPHATE PHOSPHATASE
total genus 114
structure length 336
sequence length 345
ec nomenclature ec 3.1.3.36: Phosphoinositide 5-phosphatase.
pdb deposition date 2001-03-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 1i9zA00
1NTFA 5J8NA 4B5MA 5INLA 5INKA 2JC4A 4A9CA 2DDRA 1E9NA 4B5HA 4K6LF 3G6SA 1DE8A 3K55A 5INNA 2UYRX 2A40B 5A7IA 5INPA 1VYBA 4L21A 5EWTA 1Y21A 3GA6A 3I46A 2A3ZB 1WDUA 3U8UA 4L20A 3G2CA 2DNJA 2ISIA 5DV4A 5HT2A 4RUWA 2VOAA 2IMQX 2DDTA 5CFGA 4B5GA 3WCXA 3NGQA 3G4TA 4CMLA 2XSWA 5J3SA 4QH9A 5INMA 4B5FA 1I9YA 3W3DB 5DFIA 4B5IA 3G38A 4F1IA 4PUQA 2JC5A 2DDSA 4B5JA 5DG0A 4GYZA 2V0SA 5INOA 1SR4B 4JG3A 3MPRA 4AWNA 3DNIA 4L1YA 2D1KB 3MTCA 3G8VA 1AKOA 2O3HA 1DNKA 4GEWA 4FVAA 3G3CA 4F1HB 4L1ZA 2A41B 2F2FB 3NGNA 4GZ0A 3G1KA 5J3ZA 5DFJA 3I41A 5J3PA 1I9ZA 4FPVA 4F1HA 3G3YA 3G0AA 2EI9A 3N9VA 5CFEA 1HD7A 1SI6X 3G00A 4QHDA 3W2YA 5DFFA 4CMNA 2V0RA 3G2DA 1ATND 1YJHA 4F1RA 3CJCD 3NGOA 3FZIA 2J63A 3G91A 5A7JA 2A42B 3I5VA 5INQA 3L1WA 1DEWA 1BIXA 1ZWXA 3I48A 4QHEA 4IEMA 2F1NA 5DFHA 3TEBA 5J42A 2O3CA 3NR8A 4C1RA 5DV2A 3G0RA 4LNDA 3W2XA 1DE9A 4GZ1A 4GZ2A
chains in the Genus database with same CATH superfamily
1NTFA 5J8NA 4B5MA 5INLA 5INKA 2JC4A 4A9CA 2DDRA 1E9NA 4B5HA 4K6LF 3G6SA 1DE8A 3K55A 5INNA 2UYRX 2A40B 5A7IA 5INPA 1VYBA 4L21A 5EWTA 1Y21A 3GA6A 3I46A 2A3ZB 1WDUA 3U8UA 4L20A 3G2CA 2DNJA 2ISIA 5DV4A 5HT2A 4RUWA 2VOAA 2IMQX 2DDTA 5CFGA 4B5GA 3WCXA 3NGQA 3G4TA 4CMLA 2XSWA 5J3SA 4QH9A 5INMA 4B5FA 1I9YA 3W3DB 5DFIA 4B5IA 3G38A 4F1IA 4PUQA 2JC5A 2DDSA 4B5JA 5DG0A 4GYZA 2V0SA 5INOA 1SR4B 4JG3A 3MPRA 4AWNA 3DNIA 4L1YA 2D1KB 3MTCA 3G8VA 1AKOA 2O3HA 1DNKA 4GEWA 4FVAA 3G3CA 4F1HB 4L1ZA 2A41B 2F2FB 3NGNA 4GZ0A 3G1KA 5J3ZA 5DFJA 3I41A 5J3PA 1I9ZA 4FPVA 4F1HA 3G3YA 3G0AA 2EI9A 3N9VA 5CFEA 1HD7A 1SI6X 3G00A 4QHDA 3W2YA 5DFFA 4CMNA 2V0RA 3G2DA 1ATND 1YJHA 4F1RA 3CJCD 3NGOA 3FZIA 2J63A 3G91A 5A7JA 2A42B 3I5VA 5INQA 3L1WA 1DEWA 1BIXA 1ZWXA 3I48A 4QHEA 4IEMA 2F1NA 5DFHA 3TEBA 5J42A 2O3CA 3NR8A 4C1RA 5DV2A 3G0RA 4LNDA 3W2XA 1DE9A 4GZ1A 4GZ2A
chains in the Genus database with same CATH topology
1NTFA 5J8NA 4B5MA 5INLA 5INKA 2JC4A 4A9CA 2DDRA 1E9NA 4B5HA 4K6LF 3G6SA 1DE8A 3K55A 5INNA 2UYRX 2A40B 5A7IA 5INPA 1VYBA 4L21A 5EWTA 1Y21A 3GA6A 3I46A 2A3ZB 1WDUA 3U8UA 4L20A 3G2CA 2DNJA 2ISIA 5DV4A 5HT2A 4RUWA 2VOAA 2IMQX 2DDTA 5CFGA 4B5GA 3WCXA 3NGQA 3G4TA 4CMLA 2XSWA 5J3SA 4QH9A 5INMA 4B5FA 1I9YA 3W3DB 5DFIA 4B5IA 3G38A 4F1IA 4PUQA 2JC5A 2DDSA 4B5JA 5DG0A 4GYZA 2V0SA 5INOA 1SR4B 4JG3A 3MPRA 4AWNA 3DNIA 4L1YA 2D1KB 3MTCA 3G8VA 1AKOA 2O3HA 1DNKA 4GEWA 4FVAA 3G3CA 4F1HB 4L1ZA 2A41B 2F2FB 3NGNA 4GZ0A 3G1KA 5J3ZA 5DFJA 3I41A 5J3PA 1I9ZA 4FPVA 4F1HA 3G3YA 3G0AA 2EI9A 3N9VA 5CFEA 1HD7A 1SI6X 3G00A 4QHDA 3W2YA 5DFFA 4CMNA 2V0RA 3G2DA 1ATND 1YJHA 4F1RA 3CJCD 3NGOA 3FZIA 2J63A 3G91A 5A7JA 2A42B 3I5VA 5INQA 3L1WA 1DEWA 1BIXA 1ZWXA 3I48A 4QHEA 4IEMA 2F1NA 5DFHA 3TEBA 5J42A 2O3CA 3NR8A 4C1RA 5DV2A 3G0RA 4LNDA 3W2XA 1DE9A 4GZ1A 4GZ2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NTF A;  5J8N A;  4B5M A;  5INL A;  5INK A;  2JC4 A;  4A9C A;  2DDR A;  1E9N A;  4B5H A;  4K6L F;  3G6S A;  1DE8 A;  3K55 A;  5INN A;  2UYR X;  2A40 B;  5A7I A;  5INP A;  1VYB A;  4L21 A;  5EWT A;  1Y21 A;  3GA6 A;  3I46 A;  2A3Z B;  1WDU A;  3U8U A;  4L20 A;  3G2C A;  2DNJ A;  2ISI A;  5DV4 A;  5HT2 A;  4RUW A;  2VOA A;  2IMQ X;  2DDT A;  5CFG A;  4B5G A;  3WCX A;  3NGQ A;  3G4T A;  4CML A;  2XSW A;  5J3S A;  4QH9 A;  5INM A;  4B5F A;  1I9Y A;  3W3D B;  5DFI A;  4B5I A;  3G38 A;  4F1I A;  4PUQ A;  2JC5 A;  2DDS A;  4B5J A;  5DG0 A;  4GYZ A;  2V0S A;  5INO A;  1SR4 B;  4JG3 A;  3MPR A;  4AWN A;  3DNI A;  4L1Y A;  2D1K B;  3MTC A;  3G8V A;  1AKO A;  2O3H A;  1DNK A;  4GEW A;  4FVA A;  3G3C A;  4F1H B;  4L1Z A;  2A41 B;  2F2F B;  3NGN A;  4GZ0 A;  3G1K A;  5J3Z A;  5DFJ A;  3I41 A;  5J3P A;  1I9Z A;  4FPV A;  4F1H A;  3G3Y A;  3G0A A;  2EI9 A;  3N9V A;  5CFE A;  1HD7 A;  1SI6 X;  3G00 A;  4QHD A;  3W2Y A;  5DFF A;  4CMN A;  2V0R A;  3G2D A;  1ATN D;  1YJH A;  4F1R A;  3CJC D;  3NGO A;  3FZI A;  2J63 A;  3G91 A;  5A7J A;  2A42 B;  3I5V A;  5INQ A;  3L1W A;  1DEW A;  1BIX A;  1ZWX A;  3I48 A;  4QHE A;  4IEM A;  2F1N A;  5DFH A;  3TEB A;  5J42 A;  2O3C A;  3NR8 A;  4C1R A;  5DV2 A;  3G0R A;  4LND A;  3W2X A;  1DE9 A;  4GZ1 A;  4GZ2 A; 
#chains in the Genus database with same CATH topology
 1NTF A;  5J8N A;  4B5M A;  5INL A;  5INK A;  2JC4 A;  4A9C A;  2DDR A;  1E9N A;  4B5H A;  4K6L F;  3G6S A;  1DE8 A;  3K55 A;  5INN A;  2UYR X;  2A40 B;  5A7I A;  5INP A;  1VYB A;  4L21 A;  5EWT A;  1Y21 A;  3GA6 A;  3I46 A;  2A3Z B;  1WDU A;  3U8U A;  4L20 A;  3G2C A;  2DNJ A;  2ISI A;  5DV4 A;  5HT2 A;  4RUW A;  2VOA A;  2IMQ X;  2DDT A;  5CFG A;  4B5G A;  3WCX A;  3NGQ A;  3G4T A;  4CML A;  2XSW A;  5J3S A;  4QH9 A;  5INM A;  4B5F A;  1I9Y A;  3W3D B;  5DFI A;  4B5I A;  3G38 A;  4F1I A;  4PUQ A;  2JC5 A;  2DDS A;  4B5J A;  5DG0 A;  4GYZ A;  2V0S A;  5INO A;  1SR4 B;  4JG3 A;  3MPR A;  4AWN A;  3DNI A;  4L1Y A;  2D1K B;  3MTC A;  3G8V A;  1AKO A;  2O3H A;  1DNK A;  4GEW A;  4FVA A;  3G3C A;  4F1H B;  4L1Z A;  2A41 B;  2F2F B;  3NGN A;  4GZ0 A;  3G1K A;  5J3Z A;  5DFJ A;  3I41 A;  5J3P A;  1I9Z A;  4FPV A;  4F1H A;  3G3Y A;  3G0A A;  2EI9 A;  3N9V A;  5CFE A;  1HD7 A;  1SI6 X;  3G00 A;  4QHD A;  3W2Y A;  5DFF A;  4CMN A;  2V0R A;  3G2D A;  1ATN D;  1YJH A;  4F1R A;  3CJC D;  3NGO A;  3FZI A;  2J63 A;  3G91 A;  5A7J A;  2A42 B;  3I5V A;  5INQ A;  3L1W A;  1DEW A;  1BIX A;  1ZWX A;  3I48 A;  4QHE A;  4IEM A;  2F1N A;  5DFH A;  3TEB A;  5J42 A;  2O3C A;  3NR8 A;  4C1R A;  5DV2 A;  3G0R A;  4LND A;  3W2X A;  1DE9 A;  4GZ1 A;  4GZ2 A; 
#chains in the Genus database with same CATH homology
 1NTF A;  5J8N A;  4B5M A;  5INL A;  5INK A;  2JC4 A;  4A9C A;  2DDR A;  1E9N A;  4B5H A;  4K6L F;  3G6S A;  1DE8 A;  3K55 A;  5INN A;  2UYR X;  2A40 B;  5A7I A;  5INP A;  1VYB A;  4L21 A;  5EWT A;  1Y21 A;  3GA6 A;  3I46 A;  2A3Z B;  1WDU A;  3U8U A;  4L20 A;  3G2C A;  2DNJ A;  2ISI A;  5DV4 A;  5HT2 A;  4RUW A;  2VOA A;  2IMQ X;  2DDT A;  5CFG A;  4B5G A;  3WCX A;  3NGQ A;  3G4T A;  4CML A;  2XSW A;  5J3S A;  4QH9 A;  5INM A;  4B5F A;  1I9Y A;  3W3D B;  5DFI A;  4B5I A;  3G38 A;  4F1I A;  4PUQ A;  2JC5 A;  2DDS A;  4B5J A;  5DG0 A;  4GYZ A;  2V0S A;  5INO A;  1SR4 B;  4JG3 A;  3MPR A;  4AWN A;  3DNI A;  4L1Y A;  2D1K B;  3MTC A;  3G8V A;  1AKO A;  2O3H A;  1DNK A;  4GEW A;  4FVA A;  3G3C A;  4F1H B;  4L1Z A;  2A41 B;  2F2F B;  3NGN A;  4GZ0 A;  3G1K A;  5J3Z A;  5DFJ A;  3I41 A;  5J3P A;  1I9Z A;  4FPV A;  4F1H A;  3G3Y A;  3G0A A;  2EI9 A;  3N9V A;  5CFE A;  1HD7 A;  1SI6 X;  3G00 A;  4QHD A;  3W2Y A;  5DFF A;  4CMN A;  2V0R A;  3G2D A;  1ATN D;  1YJH A;  4F1R A;  3CJC D;  3NGO A;  3FZI A;  2J63 A;  3G91 A;  5A7J A;  2A42 B;  3I5V A;  5INQ A;  3L1W A;  1DEW A;  1BIX A;  1ZWX A;  3I48 A;  4QHE A;  4IEM A;  2F1N A;  5DFH A;  3TEB A;  5J42 A;  2O3C A;  3NR8 A;  4C1R A;  5DV2 A;  3G0R A;  4LND A;  3W2X A;  1DE9 A;  4GZ1 A;  4GZ2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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