1F82A

Botulinum neurotoxin type b catalytic domain
Total Genus 127
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
127
sequence length
424
structure length
424
Chain Sequence
PVTINNFNYNDPIDNNNIIMMEPPFARGTGRYYKAFKITDRIWIIPERYTFGYKPEDFNKSSGIFNRDVCEYYDPDYLNTNDKKNIFLQTMIKLFNRIKSKPLGEKLLEMIINGIPYLGDRRVPLEEFNTNIASVTVNKLISNPGEVERKKGIFANLIIFGPGPVLNENETIDIGIQNHFASREGFGGIMQMKFCPEYVSVFNNVQENKGASIFNRRGYFSDPALILMHELIHVLHGLYGIKVDDLPIVPNEKKFFMQSTDAIQAEELYTFGGQDPSIITPSTDKSIYDKVLQNFRGIVDRLNKVLVCISDPNININIYKNKFKDKYKFVEDSEGKYSIDVESFDKLYKSLMFGFTETNIAENYKIKTRASYFSDSLPPVKIKNLLDNEIYTIEEGFNISDKDMEKEYRGQNKAINKQAYEEIS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Cocrystal structure of synaptobrevin-II bound to botulinum neurotoxin type B at 2.0 A resolution.
pubmed doi rcsb
molecule tags Toxin,hydrolase
source organism Clostridium botulinum
molecule keywords BOTULINUM NEUROTOXIN TYPE B
total genus 127
structure length 424
sequence length 424
ec nomenclature ec 3.4.24.69: Bontoxilysin.
pdb deposition date 2000-06-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01742 Peptidase_M27 Clostridial neurotoxin zinc protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1240.10 Alpha Beta Alpha-Beta Complex Zincin-like Metalloproteases ("zincins"), catalytic domain like 1f82A00
3QW8A 1ZL5A 3DS9A 3DDBA 1G9DA 3BOOA 3QIZA 4HEVA 1G9BA 3FFZA 1Z7HA 3FIEA 1F31A 4KTXA 3QJ0A 3ZUQA 3V0AA 1S0EA 2ILPA 1I1EA 2ISEA 2XHLA 1ZKXA 4J1LA 3V0BA 2G7KA 1E1HA 1S0DA 2ISHA 1ZL6A 4ELCA 3FIIA 1ZN3A 3QW5A 3C88A 4KS6A 3BONA 3D3XA 4KUFA 1ZB7A 1S0CA 5BQNA 2IMBA 3K3QB 3VUOA 1S0FA 2A97A 1F82A 3QIXA 2G7NA 3NF3A 2NP0A 2ISGA 3DDAA 4EL4A 1T3AA 3ZUSA 2IMCA 3QIYA 4EJ5A 1EPWA 1S0GA 4ZKTB 3BWIA 3BOKA 1YVGA 2ETFA 2FPQA 3V0BB 3C8BA 2W2DA 2G7PA 1ZKWA 1S0BA 3C8AA 3DSEA 3QW6A 2A8AA 1XTFA 3BTAA 3DEBA 3V0AB 3C89A 4ZJXA 2NYYA 2IMAA 2G7QA 1G9CA 5BQMA 1G9AA 3QW7A 3ZURA 1T3CA 2QN0A 2NZ9A 1XTGA
chains in the Genus database with same CATH superfamily
3QW8A 1ZL5A 3DS9A 3DDBA 1G9DA 3BOOA 3QIZA 4HEVA 1G9BA 3FFZA 1Z7HA 3FIEA 1F31A 4KTXA 3QJ0A 3ZUQA 4JIUA 3V0AA 1S0EA 2ILPA 1I1EA 4AW6A 2ISEA 2XHLA 1ZKXA 4J1LA 3V0BA 2G7KA 1E1HA 1S0DA 2ISHA 1ZL6A 4ELCA 3FIIA 1ZN3A 3QW5A 2EJQA 3C88A 4KS6A 3BONA 3D3XA 4IL3A 4KUFA 1ZB7A 1S0CA 5BQNA 2IMBA 3K3QB 3VUOA 1S0FA 2A97A 1F82A 3QIXA 2G7NA 3NF3A 2NP0A 2ISGA 3DDAA 3CQBA 4EL4A 1T3AA 3ZUSA 2IMCA 3E11A 3QIYA 4EJ5A 1EPWA 4QHFA 1S0GA 4ZKTB 3BWIA 3BOKA 1YVGA 2ETFA 2FPQA 3V0BB 3C8BA 2W2DA 2G7PA 1ZKWA 1S0BA 3C8AA 3DSEA 3QW6A 2A8AA 1XTFA 4JIXA 3BTAA 3DEBA 3V0AB 3C89A 4ZJXA 2NYYA 2IMAA 2G7QA 1G9CA 5BQMA 1G9AA 3QW7A 3ZURA 1T3CA 2YPTA 2QN0A 2NZ9A 1XTGA
chains in the Genus database with same CATH topology
3QW8A 1ZL5A 3DS9A 3DDBA 1G9DA 3BOOA 3QIZA 4HEVA 1G9BA 3FFZA 1Z7HA 3FIEA 1F31A 4KTXA 3QJ0A 3ZUQA 3V0AA 1S0EA 2ILPA 1I1EA 2ISEA 2XHLA 1ZKXA 4J1LA 3V0BA 2G7KA 1E1HA 1S0DA 2ISHA 1ZL6A 4ELCA 3FIIA 1ZN3A 3QW5A 3C88A 4KS6A 3BONA 3D3XA 4KUFA 1ZB7A 1S0CA 5BQNA 2IMBA 3K3QB 3VUOA 1S0FA 2A97A 1F82A 3QIXA 2G7NA 3NF3A 2NP0A 2ISGA 3DDAA 4EL4A 1T3AA 3ZUSA 2IMCA 3QIYA 4EJ5A 1EPWA 1S0GA 4ZKTB 3BWIA 3BOKA 1YVGA 2ETFA 2FPQA 3V0BB 3C8BA 2W2DA 2G7PA 1ZKWA 1S0BA 3C8AA 3DSEA 3QW6A 2A8AA 1XTFA 3BTAA 3DEBA 3V0AB 3C89A 4ZJXA 2NYYA 2IMAA 2G7QA 1G9CA 5BQMA 1G9AA 3QW7A 3ZURA 1T3CA 2QN0A 2NZ9A 1XTGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QW8 A;  1ZL5 A;  3DS9 A;  3DDB A;  1G9D A;  3BOO A;  3QIZ A;  4HEV A;  1G9B A;  3FFZ A;  1Z7H A;  3FIE A;  1F31 A;  4KTX A;  3QJ0 A;  3ZUQ A;  3V0A A;  1S0E A;  2ILP A;  1I1E A;  2ISE A;  2XHL A;  1ZKX A;  4J1L A;  3V0B A;  2G7K A;  1E1H A;  1S0D A;  2ISH A;  1ZL6 A;  4ELC A;  3FII A;  1ZN3 A;  3QW5 A;  3C88 A;  4KS6 A;  3BON A;  3D3X A;  4KUF A;  1ZB7 A;  1S0C A;  5BQN A;  2IMB A;  3K3Q B;  3VUO A;  1S0F A;  2A97 A;  1F82 A;  3QIX A;  2G7N A;  3NF3 A;  2NP0 A;  2ISG A;  3DDA A;  4EL4 A;  1T3A A;  3ZUS A;  2IMC A;  3QIY A;  4EJ5 A;  1EPW A;  1S0G A;  4ZKT B;  3BWI A;  3BOK A;  1YVG A;  2ETF A;  2FPQ A;  3V0B B;  3C8B A;  2W2D A;  2G7P A;  1ZKW A;  1S0B A;  3C8A A;  3DSE A;  3QW6 A;  2A8A A;  1XTF A;  3BTA A;  3DEB A;  3V0A B;  3C89 A;  4ZJX A;  2NYY A;  2IMA A;  2G7Q A;  1G9C A;  5BQM A;  1G9A A;  3QW7 A;  3ZUR A;  1T3C A;  2QN0 A;  2NZ9 A;  1XTG A; 
#chains in the Genus database with same CATH topology
 3QW8 A;  1ZL5 A;  3DS9 A;  3DDB A;  1G9D A;  3BOO A;  3QIZ A;  4HEV A;  1G9B A;  3FFZ A;  1Z7H A;  3FIE A;  1F31 A;  4KTX A;  3QJ0 A;  3ZUQ A;  4JIU A;  3V0A A;  1S0E A;  2ILP A;  1I1E A;  4AW6 A;  2ISE A;  2XHL A;  1ZKX A;  4J1L A;  3V0B A;  2G7K A;  1E1H A;  1S0D A;  2ISH A;  1ZL6 A;  4ELC A;  3FII A;  1ZN3 A;  3QW5 A;  2EJQ A;  3C88 A;  4KS6 A;  3BON A;  3D3X A;  4IL3 A;  4KUF A;  1ZB7 A;  1S0C A;  5BQN A;  2IMB A;  3K3Q B;  3VUO A;  1S0F A;  2A97 A;  1F82 A;  3QIX A;  2G7N A;  3NF3 A;  2NP0 A;  2ISG A;  3DDA A;  3CQB A;  4EL4 A;  1T3A A;  3ZUS A;  2IMC A;  3E11 A;  3QIY A;  4EJ5 A;  1EPW A;  4QHF A;  1S0G A;  4ZKT B;  3BWI A;  3BOK A;  1YVG A;  2ETF A;  2FPQ A;  3V0B B;  3C8B A;  2W2D A;  2G7P A;  1ZKW A;  1S0B A;  3C8A A;  3DSE A;  3QW6 A;  2A8A A;  1XTF A;  4JIX A;  3BTA A;  3DEB A;  3V0A B;  3C89 A;  4ZJX A;  2NYY A;  2IMA A;  2G7Q A;  1G9C A;  5BQM A;  1G9A A;  3QW7 A;  3ZUR A;  1T3C A;  2YPT A;  2QN0 A;  2NZ9 A;  1XTG A; 
#chains in the Genus database with same CATH homology
 3QW8 A;  1ZL5 A;  3DS9 A;  3DDB A;  1G9D A;  3BOO A;  3QIZ A;  4HEV A;  1G9B A;  3FFZ A;  1Z7H A;  3FIE A;  1F31 A;  4KTX A;  3QJ0 A;  3ZUQ A;  3V0A A;  1S0E A;  2ILP A;  1I1E A;  2ISE A;  2XHL A;  1ZKX A;  4J1L A;  3V0B A;  2G7K A;  1E1H A;  1S0D A;  2ISH A;  1ZL6 A;  4ELC A;  3FII A;  1ZN3 A;  3QW5 A;  3C88 A;  4KS6 A;  3BON A;  3D3X A;  4KUF A;  1ZB7 A;  1S0C A;  5BQN A;  2IMB A;  3K3Q B;  3VUO A;  1S0F A;  2A97 A;  1F82 A;  3QIX A;  2G7N A;  3NF3 A;  2NP0 A;  2ISG A;  3DDA A;  4EL4 A;  1T3A A;  3ZUS A;  2IMC A;  3QIY A;  4EJ5 A;  1EPW A;  1S0G A;  4ZKT B;  3BWI A;  3BOK A;  1YVG A;  2ETF A;  2FPQ A;  3V0B B;  3C8B A;  2W2D A;  2G7P A;  1ZKW A;  1S0B A;  3C8A A;  3DSE A;  3QW6 A;  2A8A A;  1XTF A;  3BTA A;  3DEB A;  3V0A B;  3C89 A;  4ZJX A;  2NYY A;  2IMA A;  2G7Q A;  1G9C A;  5BQM A;  1G9A A;  3QW7 A;  3ZUR A;  1T3C A;  2QN0 A;  2NZ9 A;  1XTG A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...