1F82 | Genus

Total Genus 127

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	127
sequence length	424
structure length	424
Chain Sequence	PVTINNFNYNDPIDNNNIIMMEPPFARGTGRYYKAFKITDRIWIIPERYTFGYKPEDFNKSSGIFNRDVCEYYDPDYLNTNDKKNIFLQTMIKLFNRIKSKPLGEKLLEMIINGIPYLGDRRVPLEEFNTNIASVTVNKLISNPGEVERKKGIFANLIIFGPGPVLNENETIDIGIQNHFASREGFGGIMQMKFCPEYVSVFNNVQENKGASIFNRRGYFSDPALILMHELIHVLHGLYGIKVDDLPIVPNEKKFFMQSTDAIQAEELYTFGGQDPSIITPSTDKSIYDKVLQNFRGIVDRLNKVLVCISDPNININIYKNKFKDKYKFVEDSEGKYSIDVESFDKLYKSLMFGFTETNIAENYKIKTRASYFSDSLPPVKIKNLLDNEIYTIEEGFNISDKDMEKEYRGQNKAINKQAYEEIS

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Toxin,hydrolase
source organism	Clostridium botulinum
publication title	Cocrystal structure of synaptobrevin-II bound to botulinum neurotoxin type B at 2.0 A resolution. pubmed doi rcsb
molecule keywords	BOTULINUM NEUROTOXIN TYPE B
total genus	127
structure length	424
sequence length	424
ec nomenclature	ec 3.4.24.69: Bontoxilysin.
pdb deposition date	2000-06-28

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01742	Peptidase_M27	Clostridial neurotoxin zinc protease

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.90.1240.10	Alpha Beta	Alpha-Beta Complex	Zincin-like	Metalloproteases ("zincins"), catalytic domain like	1f82A00

3BTAA 1ZN3A 2QN0A 3ZURA 3V0BA 4HEVA 4KS6A 3DS9A 3QW6A 2IMAA 1ZL6A 1ZL5A 3BONA 1EPWA 1S0GA 1S0DA 1E1HA 3NF3A 3FFZA 2W2DA 3V0BB 1G9DA 2FPQA 4KUFA 1T3CA 4ZJXA 4EJ5A 1XTGA 2NP0A 3ZUSA 3K3QB 2NYYA 3QIZA 4ELCA 1S0BA 4ZKTB 3D3XA 1S0CA 3QIYA 3ZUQA 3DDBA 2ISGA 1S0FA 4KTXA 1S0EA 3QW8A 2G7QA 2IMBA 2G7NA 3C89A 2NZ9A 2XHLA 3BOOA 1T3AA 1Z7HA 3V0AB 3QW5A 3C8BA 4EL4A 1F31A 3FIEA 1I1EA 2A8AA 1G9BA 5BQNA 5BQMA 1ZKXA 2G7PA 1YVGA 3BOKA 3FIIA 2G7KA 1XTFA 3V0AA 3DDAA 2IMCA 3C8AA 2ISEA 3QJ0A 2ISHA 1G9AA 3DSEA 4J1LA 3DEBA 3QIXA 1G9CA 3BWIA 3QW7A 1ZKWA 3VUOA 2A97A 3C88A 1F82A 2ILPA 2ETFA 1ZB7A
chains in the Genus database with same CATH superfamily

3BTAA 1ZN3A 2QN0A 3ZURA 3V0BA 4HEVA 4KS6A 3DS9A 3QW6A 2IMAA 1ZL6A 1ZL5A 3BONA 1EPWA 1S0GA 1S0DA 1E1HA 3NF3A 3FFZA 2W2DA 4QHFA 3V0BB 1G9DA 2FPQA 4KUFA 1T3CA 4ZJXA 4EJ5A 1XTGA 2NP0A 3ZUSA 3K3QB 2NYYA 3QIZA 4ELCA 1S0BA 4ZKTB 3D3XA 1S0CA 3QIYA 3ZUQA 3DDBA 2ISGA 1S0FA 3CQBA 4KTXA 1S0EA 3QW8A 2G7QA 2IMBA 2G7NA 2EJQA 3C89A 2NZ9A 4IL3A 2XHLA 3BOOA 4AW6A 1T3AA 3E11A 1Z7HA 3V0AB 3QW5A 3C8BA 4EL4A 1F31A 3FIEA 1I1EA 2A8AA 1G9BA 5BQNA 5BQMA 1ZKXA 2G7PA 1YVGA 3BOKA 3FIIA 2G7KA 1XTFA 3V0AA 3DDAA 4JIUA 2IMCA 3C8AA 2ISEA 3QJ0A 2YPTA 2ISHA 1G9AA 3DSEA 4J1LA 3DEBA 4JIXA 3QIXA 1G9CA 3BWIA 3QW7A 1ZKWA 3VUOA 2A97A 3C88A 1F82A 2ILPA 2ETFA 1ZB7A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 3BTA A;  1ZN3 A;  2QN0 A;  3ZUR A;  3V0B A;  4HEV A;  4KS6 A;  3DS9 A;  3QW6 A;  2IMA A;  1ZL6 A;  1ZL5 A;  3BON A;  1EPW A;  1S0G A;  1S0D A;  1E1H A;  3NF3 A;  3FFZ A;  2W2D A;  3V0B B;  1G9D A;  2FPQ A;  4KUF A;  1T3C A;  4ZJX A;  4EJ5 A;  1XTG A;  2NP0 A;  3ZUS A;  3K3Q B;  2NYY A;  3QIZ A;  4ELC A;  1S0B A;  4ZKT B;  3D3X A;  1S0C A;  3QIY A;  3ZUQ A;  3DDB A;  2ISG A;  1S0F A;  4KTX A;  1S0E A;  3QW8 A;  2G7Q A;  2IMB A;  2G7N A;  3C89 A;  2NZ9 A;  2XHL A;  3BOO A;  1T3A A;  1Z7H A;  3V0A B;  3QW5 A;  3C8B A;  4EL4 A;  1F31 A;  3FIE A;  1I1E A;  2A8A A;  1G9B A;  5BQN A;  5BQM A;  1ZKX A;  2G7P A;  1YVG A;  3BOK A;  3FII A;  2G7K A;  1XTF A;  3V0A A;  3DDA A;  2IMC A;  3C8A A;  2ISE A;  3QJ0 A;  2ISH A;  1G9A A;  3DSE A;  4J1L A;  3DEB A;  3QIX A;  1G9C A;  3BWI A;  3QW7 A;  1ZKW A;  3VUO A;  2A97 A;  3C88 A;  1F82 A;  2ILP A;  2ETF A;  1ZB7 A; 
#chains in the Genus database with same CATH topology
 3BTA A;  1ZN3 A;  2QN0 A;  3ZUR A;  3V0B A;  4HEV A;  4KS6 A;  3DS9 A;  3QW6 A;  2IMA A;  1ZL6 A;  1ZL5 A;  3BON A;  1EPW A;  1S0G A;  1S0D A;  1E1H A;  3NF3 A;  3FFZ A;  2W2D A;  4QHF A;  3V0B B;  1G9D A;  2FPQ A;  4KUF A;  1T3C A;  4ZJX A;  4EJ5 A;  1XTG A;  2NP0 A;  3ZUS A;  3K3Q B;  2NYY A;  3QIZ A;  4ELC A;  1S0B A;  4ZKT B;  3D3X A;  1S0C A;  3QIY A;  3ZUQ A;  3DDB A;  2ISG A;  1S0F A;  3CQB A;  4KTX A;  1S0E A;  3QW8 A;  2G7Q A;  2IMB A;  2G7N A;  2EJQ A;  3C89 A;  2NZ9 A;  4IL3 A;  2XHL A;  3BOO A;  4AW6 A;  1T3A A;  3E11 A;  1Z7H A;  3V0A B;  3QW5 A;  3C8B A;  4EL4 A;  1F31 A;  3FIE A;  1I1E A;  2A8A A;  1G9B A;  5BQN A;  5BQM A;  1ZKX A;  2G7P A;  1YVG A;  3BOK A;  3FII A;  2G7K A;  1XTF A;  3V0A A;  3DDA A;  4JIU A;  2IMC A;  3C8A A;  2ISE A;  3QJ0 A;  2YPT A;  2ISH A;  1G9A A;  3DSE A;  4J1L A;  3DEB A;  4JIX A;  3QIX A;  1G9C A;  3BWI A;  3QW7 A;  1ZKW A;  3VUO A;  2A97 A;  3C88 A;  1F82 A;  2ILP A;  2ETF A;  1ZB7 A; 
#chains in the Genus database with same CATH homology
 3BTA A;  1ZN3 A;  2QN0 A;  3ZUR A;  3V0B A;  4HEV A;  4KS6 A;  3DS9 A;  3QW6 A;  2IMA A;  1ZL6 A;  1ZL5 A;  3BON A;  1EPW A;  1S0G A;  1S0D A;  1E1H A;  3NF3 A;  3FFZ A;  2W2D A;  3V0B B;  1G9D A;  2FPQ A;  4KUF A;  1T3C A;  4ZJX A;  4EJ5 A;  1XTG A;  2NP0 A;  3ZUS A;  3K3Q B;  2NYY A;  3QIZ A;  4ELC A;  1S0B A;  4ZKT B;  3D3X A;  1S0C A;  3QIY A;  3ZUQ A;  3DDB A;  2ISG A;  1S0F A;  4KTX A;  1S0E A;  3QW8 A;  2G7Q A;  2IMB A;  2G7N A;  3C89 A;  2NZ9 A;  2XHL A;  3BOO A;  1T3A A;  1Z7H A;  3V0A B;  3QW5 A;  3C8B A;  4EL4 A;  1F31 A;  3FIE A;  1I1E A;  2A8A A;  1G9B A;  5BQN A;  5BQM A;  1ZKX A;  2G7P A;  1YVG A;  3BOK A;  3FII A;  2G7K A;  1XTF A;  3V0A A;  3DDA A;  2IMC A;  3C8A A;  2ISE A;  3QJ0 A;  2ISH A;  1G9A A;  3DSE A;  4J1L A;  3DEB A;  3QIX A;  1G9C A;  3BWI A;  3QW7 A;  1ZKW A;  3VUO A;  2A97 A;  3C88 A;  1F82 A;  2ILP A;  2ETF A;  1ZB7 A;

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similar chains in the Genus database (?% sequence similarity)

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1F82A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations