1I9ZA

Crystal structure of inositol polyphosphate 5-phosphatase domain (ipp5c) of spsynaptojanin in complex with inositol (1,4)-bisphosphate and calcium ion
Total Genus 114
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
114
sequence length
345
structure length
336
Chain Sequence
YDPIHEYVNHELRKRENEFSEHKNVKIFVASYNLNGCSATTKLENWLFPENTPLADIYVVGFQEIVQLTSADPAKRREWESCVKRLLNGKCTSGPGYVQLRSGQLVGTALMIFCKESCLPSIKNVEGTVKKTGLGNKGAVAIRFDYEDTGLCFITSHLAAGYTNYDERDHDYRTIASGLRFRRGRSIFNHDYVVWFGDFNYRISLTYEEVVPCIAQGKLSYLFEYDQLNKQMLTGKVFPFFSELPITFPPTYKFDIGTDIYDTSDKHRVPAWTDRILYRGELVPHSYQSVPLYYSDHRPIYATYEANIVKVDREKKKILFEELYNQRKQEVRDASQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Specificity determinants in phosphoinositide dephosphorylation: crystal structure of an archetypal inositol polyphosphate 5-phosphatase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Schizosaccharomyces pombe
molecule keywords PHOSPHATIDYLINOSITOL PHOSPHATE PHOSPHATASE
total genus 114
structure length 336
sequence length 345
ec nomenclature ec 3.1.3.36: Phosphoinositide 5-phosphatase.
pdb deposition date 2001-03-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 1i9zA00
2F2FB 4QHEA 4A9CA 2O3CA 4L20A 4C1RA 5DFFA 1YJHA 5J42A 3G38A 3I46A 1SI6X 3W2XA 4GEWA 4GZ1A 2V0RA 3TEBA 3G3YA 1DNKA 2A40B 3NGNA 2A41B 3NGQA 4RUWA 5DFJA 3MPRA 5J3SA 4QHDA 5EWTA 2V0SA 3G4TA 5J8NA 3G2CA 2D1KB 3G0RA 2DDSA 3G3CA 3G0AA 4QH9A 5A7JA 4GZ2A 5INOA 3L1WA 3FZIA 3NGOA 5INKA 2IMQX 2UYRX 5DFHA 1E9NA 5DV2A 4L21A 2J63A 4IEMA 3W3DB 1DE9A 3N9VA 5CFEA 4LNDA 4GYZA 4B5GA 1ZWXA 2F1NA 2O3HA 5INQA 4F1RA 1DEWA 4B5FA 2JC5A 3G00A 1SR4B 3W2YA 3GA6A 1VYBA 4F1HA 5INNA 5INPA 2DDRA 3G6SA 1HD7A 4B5JA 3I5VA 5HT2A 3G8VA 3G91A 3NR8A 3I48A 4B5HA 2A3ZB 4FVAA 3G2DA 4JG3A 1AKOA 2XSWA 1ATND 5DG0A 4L1ZA 4CMLA 4F1HB 5DV4A 1DE8A 3K55A 5INLA 2EI9A 3G1KA 4L1YA 5CFGA 4PUQA 2VOAA 5INMA 5DFIA 5J3ZA 2A42B 4B5MA 5A7IA 2JC4A 4AWNA 4F1IA 1Y21A 3WCXA 1WDUA 3U8UA 2DNJA 4B5IA 1BIXA 3I41A 2DDTA 3DNIA 1I9ZA 5J3PA 4GZ0A 1I9YA 2ISIA 4FPVA 3MTCA 4CMNA 4K6LF 1NTFA 3CJCD
chains in the Genus database with same CATH superfamily
2F2FB 4QHEA 4A9CA 2O3CA 4L20A 4C1RA 5DFFA 1YJHA 5J42A 3G38A 3I46A 1SI6X 3W2XA 4GEWA 4GZ1A 2V0RA 3TEBA 3G3YA 1DNKA 2A40B 3NGNA 2A41B 3NGQA 4RUWA 5DFJA 3MPRA 5J3SA 4QHDA 5EWTA 2V0SA 3G4TA 5J8NA 3G2CA 2D1KB 3G0RA 2DDSA 3G3CA 3G0AA 4QH9A 5A7JA 4GZ2A 5INOA 3L1WA 3FZIA 3NGOA 5INKA 2IMQX 2UYRX 5DFHA 1E9NA 5DV2A 4L21A 2J63A 4IEMA 3W3DB 1DE9A 3N9VA 5CFEA 4LNDA 4GYZA 4B5GA 1ZWXA 2F1NA 2O3HA 5INQA 4F1RA 1DEWA 4B5FA 2JC5A 3G00A 1SR4B 3W2YA 3GA6A 1VYBA 4F1HA 5INNA 5INPA 2DDRA 3G6SA 1HD7A 4B5JA 3I5VA 5HT2A 3G8VA 3G91A 3NR8A 3I48A 4B5HA 2A3ZB 4FVAA 3G2DA 4JG3A 1AKOA 2XSWA 1ATND 5DG0A 4L1ZA 4CMLA 4F1HB 5DV4A 1DE8A 3K55A 5INLA 2EI9A 3G1KA 4L1YA 5CFGA 4PUQA 2VOAA 5INMA 5DFIA 5J3ZA 2A42B 4B5MA 5A7IA 2JC4A 4AWNA 4F1IA 1Y21A 3WCXA 1WDUA 3U8UA 2DNJA 4B5IA 1BIXA 3I41A 2DDTA 3DNIA 1I9ZA 5J3PA 4GZ0A 1I9YA 2ISIA 4FPVA 3MTCA 4CMNA 4K6LF 1NTFA 3CJCD
chains in the Genus database with same CATH topology
2F2FB 4QHEA 4A9CA 2O3CA 4L20A 4C1RA 5DFFA 1YJHA 5J42A 3G38A 3I46A 1SI6X 3W2XA 4GEWA 4GZ1A 2V0RA 3TEBA 3G3YA 1DNKA 2A40B 3NGNA 2A41B 3NGQA 4RUWA 5DFJA 3MPRA 5J3SA 4QHDA 5EWTA 2V0SA 3G4TA 5J8NA 3G2CA 2D1KB 3G0RA 2DDSA 3G3CA 3G0AA 4QH9A 5A7JA 4GZ2A 5INOA 3L1WA 3FZIA 3NGOA 5INKA 2IMQX 2UYRX 5DFHA 1E9NA 5DV2A 4L21A 2J63A 4IEMA 3W3DB 1DE9A 3N9VA 5CFEA 4LNDA 4GYZA 4B5GA 1ZWXA 2F1NA 2O3HA 5INQA 4F1RA 1DEWA 4B5FA 2JC5A 3G00A 1SR4B 3W2YA 3GA6A 1VYBA 4F1HA 5INNA 5INPA 2DDRA 3G6SA 1HD7A 4B5JA 3I5VA 5HT2A 3G8VA 3G91A 3NR8A 3I48A 4B5HA 2A3ZB 4FVAA 3G2DA 4JG3A 1AKOA 2XSWA 1ATND 5DG0A 4L1ZA 4CMLA 4F1HB 5DV4A 1DE8A 3K55A 5INLA 2EI9A 3G1KA 4L1YA 5CFGA 4PUQA 2VOAA 5INMA 5DFIA 5J3ZA 2A42B 4B5MA 5A7IA 2JC4A 4AWNA 4F1IA 1Y21A 3WCXA 1WDUA 3U8UA 2DNJA 4B5IA 1BIXA 3I41A 2DDTA 3DNIA 1I9ZA 5J3PA 4GZ0A 1I9YA 2ISIA 4FPVA 3MTCA 4CMNA 4K6LF 1NTFA 3CJCD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2F2F B;  4QHE A;  4A9C A;  2O3C A;  4L20 A;  4C1R A;  5DFF A;  1YJH A;  5J42 A;  3G38 A;  3I46 A;  1SI6 X;  3W2X A;  4GEW A;  4GZ1 A;  2V0R A;  3TEB A;  3G3Y A;  1DNK A;  2A40 B;  3NGN A;  2A41 B;  3NGQ A;  4RUW A;  5DFJ A;  3MPR A;  5J3S A;  4QHD A;  5EWT A;  2V0S A;  3G4T A;  5J8N A;  3G2C A;  2D1K B;  3G0R A;  2DDS A;  3G3C A;  3G0A A;  4QH9 A;  5A7J A;  4GZ2 A;  5INO A;  3L1W A;  3FZI A;  3NGO A;  5INK A;  2IMQ X;  2UYR X;  5DFH A;  1E9N A;  5DV2 A;  4L21 A;  2J63 A;  4IEM A;  3W3D B;  1DE9 A;  3N9V A;  5CFE A;  4LND A;  4GYZ A;  4B5G A;  1ZWX A;  2F1N A;  2O3H A;  5INQ A;  4F1R A;  1DEW A;  4B5F A;  2JC5 A;  3G00 A;  1SR4 B;  3W2Y A;  3GA6 A;  1VYB A;  4F1H A;  5INN A;  5INP A;  2DDR A;  3G6S A;  1HD7 A;  4B5J A;  3I5V A;  5HT2 A;  3G8V A;  3G91 A;  3NR8 A;  3I48 A;  4B5H A;  2A3Z B;  4FVA A;  3G2D A;  4JG3 A;  1AKO A;  2XSW A;  1ATN D;  5DG0 A;  4L1Z A;  4CML A;  4F1H B;  5DV4 A;  1DE8 A;  3K55 A;  5INL A;  2EI9 A;  3G1K A;  4L1Y A;  5CFG A;  4PUQ A;  2VOA A;  5INM A;  5DFI A;  5J3Z A;  2A42 B;  4B5M A;  5A7I A;  2JC4 A;  4AWN A;  4F1I A;  1Y21 A;  3WCX A;  1WDU A;  3U8U A;  2DNJ A;  4B5I A;  1BIX A;  3I41 A;  2DDT A;  3DNI A;  1I9Z A;  5J3P A;  4GZ0 A;  1I9Y A;  2ISI A;  4FPV A;  3MTC A;  4CMN A;  4K6L F;  1NTF A;  3CJC D; 
#chains in the Genus database with same CATH topology
 2F2F B;  4QHE A;  4A9C A;  2O3C A;  4L20 A;  4C1R A;  5DFF A;  1YJH A;  5J42 A;  3G38 A;  3I46 A;  1SI6 X;  3W2X A;  4GEW A;  4GZ1 A;  2V0R A;  3TEB A;  3G3Y A;  1DNK A;  2A40 B;  3NGN A;  2A41 B;  3NGQ A;  4RUW A;  5DFJ A;  3MPR A;  5J3S A;  4QHD A;  5EWT A;  2V0S A;  3G4T A;  5J8N A;  3G2C A;  2D1K B;  3G0R A;  2DDS A;  3G3C A;  3G0A A;  4QH9 A;  5A7J A;  4GZ2 A;  5INO A;  3L1W A;  3FZI A;  3NGO A;  5INK A;  2IMQ X;  2UYR X;  5DFH A;  1E9N A;  5DV2 A;  4L21 A;  2J63 A;  4IEM A;  3W3D B;  1DE9 A;  3N9V A;  5CFE A;  4LND A;  4GYZ A;  4B5G A;  1ZWX A;  2F1N A;  2O3H A;  5INQ A;  4F1R A;  1DEW A;  4B5F A;  2JC5 A;  3G00 A;  1SR4 B;  3W2Y A;  3GA6 A;  1VYB A;  4F1H A;  5INN A;  5INP A;  2DDR A;  3G6S A;  1HD7 A;  4B5J A;  3I5V A;  5HT2 A;  3G8V A;  3G91 A;  3NR8 A;  3I48 A;  4B5H A;  2A3Z B;  4FVA A;  3G2D A;  4JG3 A;  1AKO A;  2XSW A;  1ATN D;  5DG0 A;  4L1Z A;  4CML A;  4F1H B;  5DV4 A;  1DE8 A;  3K55 A;  5INL A;  2EI9 A;  3G1K A;  4L1Y A;  5CFG A;  4PUQ A;  2VOA A;  5INM A;  5DFI A;  5J3Z A;  2A42 B;  4B5M A;  5A7I A;  2JC4 A;  4AWN A;  4F1I A;  1Y21 A;  3WCX A;  1WDU A;  3U8U A;  2DNJ A;  4B5I A;  1BIX A;  3I41 A;  2DDT A;  3DNI A;  1I9Z A;  5J3P A;  4GZ0 A;  1I9Y A;  2ISI A;  4FPV A;  3MTC A;  4CMN A;  4K6L F;  1NTF A;  3CJC D; 
#chains in the Genus database with same CATH homology
 2F2F B;  4QHE A;  4A9C A;  2O3C A;  4L20 A;  4C1R A;  5DFF A;  1YJH A;  5J42 A;  3G38 A;  3I46 A;  1SI6 X;  3W2X A;  4GEW A;  4GZ1 A;  2V0R A;  3TEB A;  3G3Y A;  1DNK A;  2A40 B;  3NGN A;  2A41 B;  3NGQ A;  4RUW A;  5DFJ A;  3MPR A;  5J3S A;  4QHD A;  5EWT A;  2V0S A;  3G4T A;  5J8N A;  3G2C A;  2D1K B;  3G0R A;  2DDS A;  3G3C A;  3G0A A;  4QH9 A;  5A7J A;  4GZ2 A;  5INO A;  3L1W A;  3FZI A;  3NGO A;  5INK A;  2IMQ X;  2UYR X;  5DFH A;  1E9N A;  5DV2 A;  4L21 A;  2J63 A;  4IEM A;  3W3D B;  1DE9 A;  3N9V A;  5CFE A;  4LND A;  4GYZ A;  4B5G A;  1ZWX A;  2F1N A;  2O3H A;  5INQ A;  4F1R A;  1DEW A;  4B5F A;  2JC5 A;  3G00 A;  1SR4 B;  3W2Y A;  3GA6 A;  1VYB A;  4F1H A;  5INN A;  5INP A;  2DDR A;  3G6S A;  1HD7 A;  4B5J A;  3I5V A;  5HT2 A;  3G8V A;  3G91 A;  3NR8 A;  3I48 A;  4B5H A;  2A3Z B;  4FVA A;  3G2D A;  4JG3 A;  1AKO A;  2XSW A;  1ATN D;  5DG0 A;  4L1Z A;  4CML A;  4F1H B;  5DV4 A;  1DE8 A;  3K55 A;  5INL A;  2EI9 A;  3G1K A;  4L1Y A;  5CFG A;  4PUQ A;  2VOA A;  5INM A;  5DFI A;  5J3Z A;  2A42 B;  4B5M A;  5A7I A;  2JC4 A;  4AWN A;  4F1I A;  1Y21 A;  3WCX A;  1WDU A;  3U8U A;  2DNJ A;  4B5I A;  1BIX A;  3I41 A;  2DDT A;  3DNI A;  1I9Z A;  5J3P A;  4GZ0 A;  1I9Y A;  2ISI A;  4FPV A;  3MTC A;  4CMN A;  4K6L F;  1NTF A;  3CJC D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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