1ZN3 | Genus

Total Genus 127

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	127
sequence length	411
structure length	411
Chain Sequence	PKINSFNYNDPVNDRTILYIKPGGCQEFYKSFNIMKNIWIIPERNVIGTTPQDFHPPTSLKNGDSSYYDPNYLQSDEEKDRFLKIVTKIFNRINNNLSGGILLEELSKANPYLGNDNTPDNQFHIGDASAVEIKFSNGSQDILLPNVIIMGAEPDLFETNSSNISLRNNYMPSNHGFGSIAIVTFSPEYSFRFNDNSMNEFIQDPALTLMHELIHSLHGLYGAKGITTKYTITQKQNPLITNIRGTNIEEFLTFGGTDLNIITSAQSNDIYTNLLADYKKIASKLSKVQVSNPLLNPYKDVFEAKYGLDKDASGIYSVNINKFNDIFKKLYSFTAFDLATKFQVKCRQTYIGQYKYFKLSNLLNDSIYNISEGYNINNLKVNFRGQNANLNPRIITPITGRGLVKKIIRFC

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Hydrolase
source organism	Clostridium botulinum
publication title	Analysis of Active Site Residues of Botulinum Neurotoxin E by Mutational, Functional, and Structural Studies: Glu335Gln Is an Apoenzyme. pubmed doi rcsb
molecule keywords	botulinum neurotoxin type E
total genus	127
structure length	411
sequence length	411
chains with identical sequence	B
ec nomenclature	ec 3.4.24.69: Bontoxilysin.
pdb deposition date	2005-05-11

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01742	Peptidase_M27	Clostridial neurotoxin zinc protease

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.90.1240.10	Alpha Beta	Alpha-Beta Complex	Zincin-like	Metalloproteases ("zincins"), catalytic domain like	1zn3A00

3C8BA 2ISGA 1ZB7A 1E1HA 1I1EA 4ELCA 3BWIA 3QIZA 4KS6A 1T3CA 3FIIA 1ZL5A 2W2DA 1G9AA 1S0CA 3ZUSA 3QJ0A 3QW5A 2FPQA 3DDBA 3QW8A 3BONA 3FIEA 5BQNA 1G9DA 2ILPA 3DEBA 1XTGA 1ZKWA 5BQMA 2QN0A 3ZUQA 1YVGA 3QW6A 3V0AA 4EJ5A 3C8AA 3DS9A 2XHLA 3QIXA 3V0AB 2G7KA 4ZKTB 1S0BA 2IMAA 1G9BA 1S0FA 2A8AA 2G7QA 3BOKA 3BOOA 3DSEA 1EPWA 4EL4A 1S0DA 3VUOA 2NZ9A 2IMBA 2G7NA 4J1LA 2ISHA 3K3QB 1XTFA 3NF3A 2IMCA 1T3AA 3V0BA 3C89A 1G9CA 3V0BB 3QW7A 2G7PA 1F82A 3ZURA 1ZL6A 1F31A 3D3XA 2ISEA 2ETFA 1ZKXA 4KTXA 1S0GA 3DDAA 4ZJXA 4HEVA 2NYYA 3FFZA 2A97A 1Z7HA 3C88A 3BTAA 1ZN3A 1S0EA 4KUFA 2NP0A 3QIYA
chains in the Genus database with same CATH superfamily

3C8BA 2ISGA 1ZB7A 1E1HA 1I1EA 4ELCA 3BWIA 3QIZA 4KS6A 1T3CA 3FIIA 1ZL5A 2W2DA 1G9AA 1S0CA 3ZUSA 3QJ0A 3QW5A 2FPQA 3DDBA 3QW8A 4AW6A 3BONA 3FIEA 5BQNA 1G9DA 2ILPA 3DEBA 1XTGA 1ZKWA 5BQMA 2QN0A 3ZUQA 1YVGA 3QW6A 3V0AA 4EJ5A 3C8AA 3DS9A 4IL3A 2XHLA 3QIXA 3V0AB 2G7KA 4ZKTB 1S0BA 4QHFA 3CQBA 2IMAA 1G9BA 1S0FA 2A8AA 2G7QA 3BOKA 3BOOA 4JIUA 3DSEA 1EPWA 4EL4A 1S0DA 3E11A 3VUOA 2EJQA 2NZ9A 2IMBA 2G7NA 4J1LA 2ISHA 3K3QB 1XTFA 3NF3A 2YPTA 2IMCA 1T3AA 3V0BA 3C89A 1G9CA 4JIXA 3V0BB 3QW7A 2G7PA 1F82A 3ZURA 1ZL6A 1F31A 3D3XA 2ISEA 2ETFA 1ZKXA 4KTXA 1S0GA 3DDAA 4ZJXA 4HEVA 2NYYA 3FFZA 2A97A 1Z7HA 3C88A 3BTAA 1ZN3A 1S0EA 4KUFA 2NP0A 3QIYA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 3C8B A;  2ISG A;  1ZB7 A;  1E1H A;  1I1E A;  4ELC A;  3BWI A;  3QIZ A;  4KS6 A;  1T3C A;  3FII A;  1ZL5 A;  2W2D A;  1G9A A;  1S0C A;  3ZUS A;  3QJ0 A;  3QW5 A;  2FPQ A;  3DDB A;  3QW8 A;  3BON A;  3FIE A;  5BQN A;  1G9D A;  2ILP A;  3DEB A;  1XTG A;  1ZKW A;  5BQM A;  2QN0 A;  3ZUQ A;  1YVG A;  3QW6 A;  3V0A A;  4EJ5 A;  3C8A A;  3DS9 A;  2XHL A;  3QIX A;  3V0A B;  2G7K A;  4ZKT B;  1S0B A;  2IMA A;  1G9B A;  1S0F A;  2A8A A;  2G7Q A;  3BOK A;  3BOO A;  3DSE A;  1EPW A;  4EL4 A;  1S0D A;  3VUO A;  2NZ9 A;  2IMB A;  2G7N A;  4J1L A;  2ISH A;  3K3Q B;  1XTF A;  3NF3 A;  2IMC A;  1T3A A;  3V0B A;  3C89 A;  1G9C A;  3V0B B;  3QW7 A;  2G7P A;  1F82 A;  3ZUR A;  1ZL6 A;  1F31 A;  3D3X A;  2ISE A;  2ETF A;  1ZKX A;  4KTX A;  1S0G A;  3DDA A;  4ZJX A;  4HEV A;  2NYY A;  3FFZ A;  2A97 A;  1Z7H A;  3C88 A;  3BTA A;  1ZN3 A;  1S0E A;  4KUF A;  2NP0 A;  3QIY A; 
#chains in the Genus database with same CATH topology
 3C8B A;  2ISG A;  1ZB7 A;  1E1H A;  1I1E A;  4ELC A;  3BWI A;  3QIZ A;  4KS6 A;  1T3C A;  3FII A;  1ZL5 A;  2W2D A;  1G9A A;  1S0C A;  3ZUS A;  3QJ0 A;  3QW5 A;  2FPQ A;  3DDB A;  3QW8 A;  4AW6 A;  3BON A;  3FIE A;  5BQN A;  1G9D A;  2ILP A;  3DEB A;  1XTG A;  1ZKW A;  5BQM A;  2QN0 A;  3ZUQ A;  1YVG A;  3QW6 A;  3V0A A;  4EJ5 A;  3C8A A;  3DS9 A;  4IL3 A;  2XHL A;  3QIX A;  3V0A B;  2G7K A;  4ZKT B;  1S0B A;  4QHF A;  3CQB A;  2IMA A;  1G9B A;  1S0F A;  2A8A A;  2G7Q A;  3BOK A;  3BOO A;  4JIU A;  3DSE A;  1EPW A;  4EL4 A;  1S0D A;  3E11 A;  3VUO A;  2EJQ A;  2NZ9 A;  2IMB A;  2G7N A;  4J1L A;  2ISH A;  3K3Q B;  1XTF A;  3NF3 A;  2YPT A;  2IMC A;  1T3A A;  3V0B A;  3C89 A;  1G9C A;  4JIX A;  3V0B B;  3QW7 A;  2G7P A;  1F82 A;  3ZUR A;  1ZL6 A;  1F31 A;  3D3X A;  2ISE A;  2ETF A;  1ZKX A;  4KTX A;  1S0G A;  3DDA A;  4ZJX A;  4HEV A;  2NYY A;  3FFZ A;  2A97 A;  1Z7H A;  3C88 A;  3BTA A;  1ZN3 A;  1S0E A;  4KUF A;  2NP0 A;  3QIY A; 
#chains in the Genus database with same CATH homology
 3C8B A;  2ISG A;  1ZB7 A;  1E1H A;  1I1E A;  4ELC A;  3BWI A;  3QIZ A;  4KS6 A;  1T3C A;  3FII A;  1ZL5 A;  2W2D A;  1G9A A;  1S0C A;  3ZUS A;  3QJ0 A;  3QW5 A;  2FPQ A;  3DDB A;  3QW8 A;  3BON A;  3FIE A;  5BQN A;  1G9D A;  2ILP A;  3DEB A;  1XTG A;  1ZKW A;  5BQM A;  2QN0 A;  3ZUQ A;  1YVG A;  3QW6 A;  3V0A A;  4EJ5 A;  3C8A A;  3DS9 A;  2XHL A;  3QIX A;  3V0A B;  2G7K A;  4ZKT B;  1S0B A;  2IMA A;  1G9B A;  1S0F A;  2A8A A;  2G7Q A;  3BOK A;  3BOO A;  3DSE A;  1EPW A;  4EL4 A;  1S0D A;  3VUO A;  2NZ9 A;  2IMB A;  2G7N A;  4J1L A;  2ISH A;  3K3Q B;  1XTF A;  3NF3 A;  2IMC A;  1T3A A;  3V0B A;  3C89 A;  1G9C A;  3V0B B;  3QW7 A;  2G7P A;  1F82 A;  3ZUR A;  1ZL6 A;  1F31 A;  3D3X A;  2ISE A;  2ETF A;  1ZKX A;  4KTX A;  1S0G A;  3DDA A;  4ZJX A;  4HEV A;  2NYY A;  3FFZ A;  2A97 A;  1Z7H A;  3C88 A;  3BTA A;  1ZN3 A;  1S0E A;  4KUF A;  2NP0 A;  3QIY A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1ZN3A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations