1F82A

Botulinum neurotoxin type b catalytic domain
Total Genus 127
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
127
sequence length
424
structure length
424
Chain Sequence
PVTINNFNYNDPIDNNNIIMMEPPFARGTGRYYKAFKITDRIWIIPERYTFGYKPEDFNKSSGIFNRDVCEYYDPDYLNTNDKKNIFLQTMIKLFNRIKSKPLGEKLLEMIINGIPYLGDRRVPLEEFNTNIASVTVNKLISNPGEVERKKGIFANLIIFGPGPVLNENETIDIGIQNHFASREGFGGIMQMKFCPEYVSVFNNVQENKGASIFNRRGYFSDPALILMHELIHVLHGLYGIKVDDLPIVPNEKKFFMQSTDAIQAEELYTFGGQDPSIITPSTDKSIYDKVLQNFRGIVDRLNKVLVCISDPNININIYKNKFKDKYKFVEDSEGKYSIDVESFDKLYKSLMFGFTETNIAENYKIKTRASYFSDSLPPVKIKNLLDNEIYTIEEGFNISDKDMEKEYRGQNKAINKQAYEEIS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Cocrystal structure of synaptobrevin-II bound to botulinum neurotoxin type B at 2.0 A resolution.
pubmed doi rcsb
molecule tags Toxin,hydrolase
source organism Clostridium botulinum
molecule keywords BOTULINUM NEUROTOXIN TYPE B
total genus 127
structure length 424
sequence length 424
ec nomenclature ec 3.4.24.69: Bontoxilysin.
pdb deposition date 2000-06-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01742 Peptidase_M27 Clostridial neurotoxin zinc protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1240.10 Alpha Beta Alpha-Beta Complex Zincin-like Metalloproteases ("zincins"), catalytic domain like 1f82A00
2QN0A 3BWIA 2G7QA 3QW8A 2G7PA 3DSEA 2ISHA 3NF3A 1G9BA 3FIIA 1ZL5A 3BONA 4KS6A 2NYYA 1G9AA 3DS9A 3V0AB 1ZL6A 1ZKXA 3BOKA 2XHLA 4ZKTB 2IMAA 1E1HA 1ZN3A 4HEVA 1S0CA 1S0EA 3QIZA 1T3AA 3V0BA 3C8AA 2A97A 1Z7HA 2NZ9A 1T3CA 3BOOA 1EPWA 5BQNA 3DDAA 1S0DA 1S0FA 1XTGA 3DEBA 2ETFA 2ILPA 2W2DA 1I1EA 4J1LA 3D3XA 1ZB7A 3C8BA 1S0GA 2ISEA 2A8AA 3QW6A 3DDBA 3ZUSA 3QW7A 1G9CA 3BTAA 2IMBA 1G9DA 3QW5A 1S0BA 3V0AA 1F31A 3ZUQA 3V0BB 5BQMA 1YVGA 3FIEA 1F82A 4KUFA 3FFZA 1ZKWA 4KTXA 3K3QB 3QJ0A 4EJ5A 2ISGA 3QIXA 4ZJXA 2FPQA 3QIYA 2G7KA 3C89A 3VUOA 4EL4A 2IMCA 4ELCA 2NP0A 1XTFA 3ZURA 3C88A 2G7NA
chains in the Genus database with same CATH superfamily
2QN0A 3BWIA 2G7QA 3QW8A 2G7PA 3DSEA 2ISHA 3NF3A 1G9BA 3FIIA 1ZL5A 3BONA 4KS6A 2NYYA 1G9AA 3DS9A 3V0AB 1ZL6A 1ZKXA 2EJQA 3BOKA 2XHLA 4ZKTB 2IMAA 1E1HA 1ZN3A 4HEVA 1S0CA 1S0EA 3QIZA 1T3AA 3V0BA 2YPTA 3C8AA 4AW6A 2A97A 1Z7HA 2NZ9A 1T3CA 3BOOA 1EPWA 5BQNA 3DDAA 1S0DA 1S0FA 1XTGA 3DEBA 2ETFA 2ILPA 2W2DA 1I1EA 4J1LA 3D3XA 3E11A 1ZB7A 3C8BA 1S0GA 2ISEA 2A8AA 3QW6A 3DDBA 3ZUSA 3QW7A 1G9CA 3BTAA 4JIUA 2IMBA 1G9DA 3QW5A 1S0BA 3V0AA 1F31A 3ZUQA 3V0BB 5BQMA 4JIXA 1YVGA 3CQBA 4QHFA 3FIEA 1F82A 4KUFA 3FFZA 1ZKWA 4KTXA 3K3QB 3QJ0A 4EJ5A 2ISGA 3QIXA 4ZJXA 2FPQA 3QIYA 2G7KA 3C89A 3VUOA 4EL4A 2IMCA 4IL3A 4ELCA 2NP0A 1XTFA 3ZURA 3C88A 2G7NA
chains in the Genus database with same CATH topology
2QN0A 3BWIA 2G7QA 3QW8A 2G7PA 3DSEA 2ISHA 3NF3A 1G9BA 3FIIA 1ZL5A 3BONA 4KS6A 2NYYA 1G9AA 3DS9A 3V0AB 1ZL6A 1ZKXA 3BOKA 2XHLA 4ZKTB 2IMAA 1E1HA 1ZN3A 4HEVA 1S0CA 1S0EA 3QIZA 1T3AA 3V0BA 3C8AA 2A97A 1Z7HA 2NZ9A 1T3CA 3BOOA 1EPWA 5BQNA 3DDAA 1S0DA 1S0FA 1XTGA 3DEBA 2ETFA 2ILPA 2W2DA 1I1EA 4J1LA 3D3XA 1ZB7A 3C8BA 1S0GA 2ISEA 2A8AA 3QW6A 3DDBA 3ZUSA 3QW7A 1G9CA 3BTAA 2IMBA 1G9DA 3QW5A 1S0BA 3V0AA 1F31A 3ZUQA 3V0BB 5BQMA 1YVGA 3FIEA 1F82A 4KUFA 3FFZA 1ZKWA 4KTXA 3K3QB 3QJ0A 4EJ5A 2ISGA 3QIXA 4ZJXA 2FPQA 3QIYA 2G7KA 3C89A 3VUOA 4EL4A 2IMCA 4ELCA 2NP0A 1XTFA 3ZURA 3C88A 2G7NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QN0 A;  3BWI A;  2G7Q A;  3QW8 A;  2G7P A;  3DSE A;  2ISH A;  3NF3 A;  1G9B A;  3FII A;  1ZL5 A;  3BON A;  4KS6 A;  2NYY A;  1G9A A;  3DS9 A;  3V0A B;  1ZL6 A;  1ZKX A;  3BOK A;  2XHL A;  4ZKT B;  2IMA A;  1E1H A;  1ZN3 A;  4HEV A;  1S0C A;  1S0E A;  3QIZ A;  1T3A A;  3V0B A;  3C8A A;  2A97 A;  1Z7H A;  2NZ9 A;  1T3C A;  3BOO A;  1EPW A;  5BQN A;  3DDA A;  1S0D A;  1S0F A;  1XTG A;  3DEB A;  2ETF A;  2ILP A;  2W2D A;  1I1E A;  4J1L A;  3D3X A;  1ZB7 A;  3C8B A;  1S0G A;  2ISE A;  2A8A A;  3QW6 A;  3DDB A;  3ZUS A;  3QW7 A;  1G9C A;  3BTA A;  2IMB A;  1G9D A;  3QW5 A;  1S0B A;  3V0A A;  1F31 A;  3ZUQ A;  3V0B B;  5BQM A;  1YVG A;  3FIE A;  1F82 A;  4KUF A;  3FFZ A;  1ZKW A;  4KTX A;  3K3Q B;  3QJ0 A;  4EJ5 A;  2ISG A;  3QIX A;  4ZJX A;  2FPQ A;  3QIY A;  2G7K A;  3C89 A;  3VUO A;  4EL4 A;  2IMC A;  4ELC A;  2NP0 A;  1XTF A;  3ZUR A;  3C88 A;  2G7N A; 
#chains in the Genus database with same CATH topology
 2QN0 A;  3BWI A;  2G7Q A;  3QW8 A;  2G7P A;  3DSE A;  2ISH A;  3NF3 A;  1G9B A;  3FII A;  1ZL5 A;  3BON A;  4KS6 A;  2NYY A;  1G9A A;  3DS9 A;  3V0A B;  1ZL6 A;  1ZKX A;  2EJQ A;  3BOK A;  2XHL A;  4ZKT B;  2IMA A;  1E1H A;  1ZN3 A;  4HEV A;  1S0C A;  1S0E A;  3QIZ A;  1T3A A;  3V0B A;  2YPT A;  3C8A A;  4AW6 A;  2A97 A;  1Z7H A;  2NZ9 A;  1T3C A;  3BOO A;  1EPW A;  5BQN A;  3DDA A;  1S0D A;  1S0F A;  1XTG A;  3DEB A;  2ETF A;  2ILP A;  2W2D A;  1I1E A;  4J1L A;  3D3X A;  3E11 A;  1ZB7 A;  3C8B A;  1S0G A;  2ISE A;  2A8A A;  3QW6 A;  3DDB A;  3ZUS A;  3QW7 A;  1G9C A;  3BTA A;  4JIU A;  2IMB A;  1G9D A;  3QW5 A;  1S0B A;  3V0A A;  1F31 A;  3ZUQ A;  3V0B B;  5BQM A;  4JIX A;  1YVG A;  3CQB A;  4QHF A;  3FIE A;  1F82 A;  4KUF A;  3FFZ A;  1ZKW A;  4KTX A;  3K3Q B;  3QJ0 A;  4EJ5 A;  2ISG A;  3QIX A;  4ZJX A;  2FPQ A;  3QIY A;  2G7K A;  3C89 A;  3VUO A;  4EL4 A;  2IMC A;  4IL3 A;  4ELC A;  2NP0 A;  1XTF A;  3ZUR A;  3C88 A;  2G7N A; 
#chains in the Genus database with same CATH homology
 2QN0 A;  3BWI A;  2G7Q A;  3QW8 A;  2G7P A;  3DSE A;  2ISH A;  3NF3 A;  1G9B A;  3FII A;  1ZL5 A;  3BON A;  4KS6 A;  2NYY A;  1G9A A;  3DS9 A;  3V0A B;  1ZL6 A;  1ZKX A;  3BOK A;  2XHL A;  4ZKT B;  2IMA A;  1E1H A;  1ZN3 A;  4HEV A;  1S0C A;  1S0E A;  3QIZ A;  1T3A A;  3V0B A;  3C8A A;  2A97 A;  1Z7H A;  2NZ9 A;  1T3C A;  3BOO A;  1EPW A;  5BQN A;  3DDA A;  1S0D A;  1S0F A;  1XTG A;  3DEB A;  2ETF A;  2ILP A;  2W2D A;  1I1E A;  4J1L A;  3D3X A;  1ZB7 A;  3C8B A;  1S0G A;  2ISE A;  2A8A A;  3QW6 A;  3DDB A;  3ZUS A;  3QW7 A;  1G9C A;  3BTA A;  2IMB A;  1G9D A;  3QW5 A;  1S0B A;  3V0A A;  1F31 A;  3ZUQ A;  3V0B B;  5BQM A;  1YVG A;  3FIE A;  1F82 A;  4KUF A;  3FFZ A;  1ZKW A;  4KTX A;  3K3Q B;  3QJ0 A;  4EJ5 A;  2ISG A;  3QIX A;  4ZJX A;  2FPQ A;  3QIY A;  2G7K A;  3C89 A;  3VUO A;  4EL4 A;  2IMC A;  4ELC A;  2NP0 A;  1XTF A;  3ZUR A;  3C88 A;  2G7N A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...