1ZB7A

Crystal structure of botulinum neurotoxin type g light chain
Total Genus 127
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
127
sequence length
437
structure length
414
Chain Sequence
PVNIKNFNYNDPINNDDIIMMEPFNDPGPGTYYKAFRIIDRIWIVPERFTYKDVYEYYDPTYLKTDAEKDKFLKTMIKLFNRINSKPSGQRLLDMIVDAIPYLGNASTPPDKFAANVANVSINKKIIQPGAEDQIKGLMTNLIIFGPGPVLSDNFTDSMIMNGHSPISEGFGARMMIRFCPSCLNVFNNVQENKIFSRRAYFADPALTLMHELIHVLHGLYGIKISNLPITPFMQHSDPVQAEELYTFGGHDPSVISPSTDMNIYNKALQNFQDIANRLNIVSSAQGSGIDISLYKQIYKNKYDFVEDPNGKYSVDKDKFDKLYKALMFGFTETNLAGEYGIKTRYSYFSEYLPPIKTEKLLDNTIYTQNEGFNIASKNLKTEFNGQNKAVNKEAYEEISLEHLVIYRIAMCKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of botulinum neurotoxin type g light chain: serotype divergence in substrate recognition
pubmed doi rcsb
molecule tags Toxin
source organism Clostridium botulinum
molecule keywords neurotoxin
total genus 127
structure length 414
sequence length 437
ec nomenclature ec 3.4.24.69: Bontoxilysin.
pdb deposition date 2005-04-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01742 Peptidase_M27 Clostridial neurotoxin zinc protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1240.10 Alpha Beta Alpha-Beta Complex Zincin-like Metalloproteases ("zincins"), catalytic domain like 1zb7A00
2FPQA 1S0BA 3DDAA 3BTAA 1Z7HA 3QIZA 4ZKTB 3V0BA 3BOKA 3VUOA 3V0BB 3QW6A 1EPWA 1T3AA 2QN0A 3K3QB 1ZN3A 2G7PA 2G7KA 2NP0A 3ZUSA 3QIYA 1G9DA 2ISHA 3BWIA 3BONA 3V0AB 5BQMA 1YVGA 3C8AA 1XTGA 3DSEA 2IMAA 3ZURA 3D3XA 3QW7A 1T3CA 4KUFA 3FFZA 3FIIA 1ZL5A 2G7NA 2A97A 2W2DA 3C8BA 1ZKXA 1E1HA 3NF3A 1G9BA 2XHLA 5BQNA 3DS9A 2IMCA 2ISGA 2G7QA 4ZJXA 1I1EA 2ETFA 3QIXA 1S0EA 2ILPA 1S0FA 3DDBA 1ZL6A 1S0DA 3QW5A 3ZUQA 4ELCA 1S0GA 4HEVA 2ISEA 4KS6A 4KTXA 1G9CA 1S0CA 4J1LA 3QW8A 2IMBA 2NZ9A 3DEBA 2A8AA 1F31A 3FIEA 1F82A 2NYYA 4EL4A 1XTFA 3QJ0A 4EJ5A 1G9AA 3C88A 1ZB7A 3V0AA 3BOOA 3C89A 1ZKWA
chains in the Genus database with same CATH superfamily
2FPQA 1S0BA 3DDAA 3BTAA 1Z7HA 3QIZA 4ZKTB 3CQBA 3V0BA 3BOKA 3VUOA 3V0BB 3QW6A 1EPWA 1T3AA 2QN0A 3K3QB 1ZN3A 2G7PA 2G7KA 4JIXA 2NP0A 3ZUSA 3QIYA 1G9DA 2ISHA 3BWIA 3BONA 3V0AB 5BQMA 1YVGA 3C8AA 1XTGA 3DSEA 2IMAA 3ZURA 3D3XA 3QW7A 1T3CA 4KUFA 3FFZA 3FIIA 1ZL5A 2G7NA 2A97A 2W2DA 3C8BA 1ZKXA 1E1HA 3NF3A 4JIUA 1G9BA 2XHLA 5BQNA 3DS9A 2IMCA 2EJQA 2ISGA 2G7QA 4ZJXA 1I1EA 2ETFA 3QIXA 2YPTA 1S0EA 2ILPA 1S0FA 3DDBA 1ZL6A 1S0DA 3QW5A 3ZUQA 4ELCA 1S0GA 4HEVA 2ISEA 4KS6A 4AW6A 4KTXA 1G9CA 1S0CA 4J1LA 3QW8A 2IMBA 2NZ9A 3DEBA 2A8AA 1F31A 3FIEA 1F82A 2NYYA 4EL4A 1XTFA 4QHFA 3QJ0A 4EJ5A 3E11A 1G9AA 3C88A 4IL3A 1ZB7A 3V0AA 3BOOA 3C89A 1ZKWA
chains in the Genus database with same CATH topology
2FPQA 1S0BA 3DDAA 3BTAA 1Z7HA 3QIZA 4ZKTB 3V0BA 3BOKA 3VUOA 3V0BB 3QW6A 1EPWA 1T3AA 2QN0A 3K3QB 1ZN3A 2G7PA 2G7KA 2NP0A 3ZUSA 3QIYA 1G9DA 2ISHA 3BWIA 3BONA 3V0AB 5BQMA 1YVGA 3C8AA 1XTGA 3DSEA 2IMAA 3ZURA 3D3XA 3QW7A 1T3CA 4KUFA 3FFZA 3FIIA 1ZL5A 2G7NA 2A97A 2W2DA 3C8BA 1ZKXA 1E1HA 3NF3A 1G9BA 2XHLA 5BQNA 3DS9A 2IMCA 2ISGA 2G7QA 4ZJXA 1I1EA 2ETFA 3QIXA 1S0EA 2ILPA 1S0FA 3DDBA 1ZL6A 1S0DA 3QW5A 3ZUQA 4ELCA 1S0GA 4HEVA 2ISEA 4KS6A 4KTXA 1G9CA 1S0CA 4J1LA 3QW8A 2IMBA 2NZ9A 3DEBA 2A8AA 1F31A 3FIEA 1F82A 2NYYA 4EL4A 1XTFA 3QJ0A 4EJ5A 1G9AA 3C88A 1ZB7A 3V0AA 3BOOA 3C89A 1ZKWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FPQ A;  1S0B A;  3DDA A;  3BTA A;  1Z7H A;  3QIZ A;  4ZKT B;  3V0B A;  3BOK A;  3VUO A;  3V0B B;  3QW6 A;  1EPW A;  1T3A A;  2QN0 A;  3K3Q B;  1ZN3 A;  2G7P A;  2G7K A;  2NP0 A;  3ZUS A;  3QIY A;  1G9D A;  2ISH A;  3BWI A;  3BON A;  3V0A B;  5BQM A;  1YVG A;  3C8A A;  1XTG A;  3DSE A;  2IMA A;  3ZUR A;  3D3X A;  3QW7 A;  1T3C A;  4KUF A;  3FFZ A;  3FII A;  1ZL5 A;  2G7N A;  2A97 A;  2W2D A;  3C8B A;  1ZKX A;  1E1H A;  3NF3 A;  1G9B A;  2XHL A;  5BQN A;  3DS9 A;  2IMC A;  2ISG A;  2G7Q A;  4ZJX A;  1I1E A;  2ETF A;  3QIX A;  1S0E A;  2ILP A;  1S0F A;  3DDB A;  1ZL6 A;  1S0D A;  3QW5 A;  3ZUQ A;  4ELC A;  1S0G A;  4HEV A;  2ISE A;  4KS6 A;  4KTX A;  1G9C A;  1S0C A;  4J1L A;  3QW8 A;  2IMB A;  2NZ9 A;  3DEB A;  2A8A A;  1F31 A;  3FIE A;  1F82 A;  2NYY A;  4EL4 A;  1XTF A;  3QJ0 A;  4EJ5 A;  1G9A A;  3C88 A;  1ZB7 A;  3V0A A;  3BOO A;  3C89 A;  1ZKW A; 
#chains in the Genus database with same CATH topology
 2FPQ A;  1S0B A;  3DDA A;  3BTA A;  1Z7H A;  3QIZ A;  4ZKT B;  3CQB A;  3V0B A;  3BOK A;  3VUO A;  3V0B B;  3QW6 A;  1EPW A;  1T3A A;  2QN0 A;  3K3Q B;  1ZN3 A;  2G7P A;  2G7K A;  4JIX A;  2NP0 A;  3ZUS A;  3QIY A;  1G9D A;  2ISH A;  3BWI A;  3BON A;  3V0A B;  5BQM A;  1YVG A;  3C8A A;  1XTG A;  3DSE A;  2IMA A;  3ZUR A;  3D3X A;  3QW7 A;  1T3C A;  4KUF A;  3FFZ A;  3FII A;  1ZL5 A;  2G7N A;  2A97 A;  2W2D A;  3C8B A;  1ZKX A;  1E1H A;  3NF3 A;  4JIU A;  1G9B A;  2XHL A;  5BQN A;  3DS9 A;  2IMC A;  2EJQ A;  2ISG A;  2G7Q A;  4ZJX A;  1I1E A;  2ETF A;  3QIX A;  2YPT A;  1S0E A;  2ILP A;  1S0F A;  3DDB A;  1ZL6 A;  1S0D A;  3QW5 A;  3ZUQ A;  4ELC A;  1S0G A;  4HEV A;  2ISE A;  4KS6 A;  4AW6 A;  4KTX A;  1G9C A;  1S0C A;  4J1L A;  3QW8 A;  2IMB A;  2NZ9 A;  3DEB A;  2A8A A;  1F31 A;  3FIE A;  1F82 A;  2NYY A;  4EL4 A;  1XTF A;  4QHF A;  3QJ0 A;  4EJ5 A;  3E11 A;  1G9A A;  3C88 A;  4IL3 A;  1ZB7 A;  3V0A A;  3BOO A;  3C89 A;  1ZKW A; 
#chains in the Genus database with same CATH homology
 2FPQ A;  1S0B A;  3DDA A;  3BTA A;  1Z7H A;  3QIZ A;  4ZKT B;  3V0B A;  3BOK A;  3VUO A;  3V0B B;  3QW6 A;  1EPW A;  1T3A A;  2QN0 A;  3K3Q B;  1ZN3 A;  2G7P A;  2G7K A;  2NP0 A;  3ZUS A;  3QIY A;  1G9D A;  2ISH A;  3BWI A;  3BON A;  3V0A B;  5BQM A;  1YVG A;  3C8A A;  1XTG A;  3DSE A;  2IMA A;  3ZUR A;  3D3X A;  3QW7 A;  1T3C A;  4KUF A;  3FFZ A;  3FII A;  1ZL5 A;  2G7N A;  2A97 A;  2W2D A;  3C8B A;  1ZKX A;  1E1H A;  3NF3 A;  1G9B A;  2XHL A;  5BQN A;  3DS9 A;  2IMC A;  2ISG A;  2G7Q A;  4ZJX A;  1I1E A;  2ETF A;  3QIX A;  1S0E A;  2ILP A;  1S0F A;  3DDB A;  1ZL6 A;  1S0D A;  3QW5 A;  3ZUQ A;  4ELC A;  1S0G A;  4HEV A;  2ISE A;  4KS6 A;  4KTX A;  1G9C A;  1S0C A;  4J1L A;  3QW8 A;  2IMB A;  2NZ9 A;  3DEB A;  2A8A A;  1F31 A;  3FIE A;  1F82 A;  2NYY A;  4EL4 A;  1XTF A;  3QJ0 A;  4EJ5 A;  1G9A A;  3C88 A;  1ZB7 A;  3V0A A;  3BOO A;  3C89 A;  1ZKW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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