2A41B

Ternary complex of the wh2 domain of wip with actin-dnase i
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
260
structure length
260
Chain Sequence
LKIAAFNIRTFGETKMSNATLASYIVRIVRRYDIVLIQEVRDSHLVAVGKLLDYLNQDDPNTYHYVVSEPLGRNSYKERYLFLFRPNKVSVLDTYQYDDGCESCGNDSFSREPAVVKFSSHSTKVKEFAIVALHSAPSDAVAEINSLYDVYLDVQQKWHLNDVMLMGDFNADCSYVTSSQWSSIRLRTSSTFQWLIPDSADTTATSTNCAYDRIVVAGSLLQSSVVPGSAAPFDFQAAYGLSNEMALAISDHYPVEVTLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Actin-bound structures of Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 and the implications for filament assembly
pubmed doi rcsb
molecule tags Structural protein
molecule keywords Actin, alpha skeletal muscle
total genus 91
structure length 260
sequence length 260
ec nomenclature ec 3.1.21.1: Deoxyribonuclease I.
pdb deposition date 2005-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 2a41B00
5INLA 4GEWA 4GZ2A 5J3SA 5CFEA 4LNDA 5DFJA 1DE9A 3G2DA 5DFFA 1E9NA 2VOAA 3WCXA 3NR8A 4B5FA 2DDRA 5J8NA 2JC5A 3TEBA 2JC4A 3GA6A 2DNJA 1HD7A 5J42A 3G3YA 3W3DB 4K6LF 5A7JA 5J3PA 3MTCA 4QHEA 4JG3A 4IEMA 2DDTA 4L1YA 4F1RA 1DNKA 2IMQX 1NTFA 3I46A 3G6SA 2J63A 4FPVA 1ATND 3I41A 5DFHA 4AWNA 5J3ZA 2ISIA 3G2CA 1I9YA 4B5GA 1SI6X 5DV4A 2EI9A 1AKOA 4QH9A 5INNA 5INOA 2O3CA 5A7IA 4PUQA 3G0AA 3N9VA 5DV2A 3NGOA 1DEWA 3W2XA 1VYBA 1WDUA 2XSWA 3FZIA 3CJCD 2V0RA 2DDSA 4QHDA 3G0RA 3G1KA 3G4TA 5INQA 4CMLA 5INPA 4F1HB 3DNIA 3NGNA 3G00A 3MPRA 3L1WA 1DE8A 2A40B 2V0SA 4F1IA 4B5MA 2A41B 4CMNA 3K55A 1Y21A 5EWTA 3U8UA 3G8VA 5INMA 1ZWXA 4B5JA 5INKA 1BIXA 4GYZA 3W2YA 2F2FB 5DG0A 1I9ZA 3I5VA 2O3HA 3G38A 1YJHA 5HT2A 2A3ZB 4RUWA 5CFGA 4C1RA 4F1HA 4L1ZA 3NGQA 1SR4B 4GZ1A 2UYRX 4A9CA 3G3CA 4L20A 3G91A 4B5IA 2F1NA 2D1KB 4GZ0A 4L21A 4FVAA 4B5HA 5DFIA 3I48A 2A42B
chains in the Genus database with same CATH superfamily
5INLA 4GEWA 4GZ2A 5J3SA 5CFEA 4LNDA 5DFJA 1DE9A 3G2DA 5DFFA 1E9NA 2VOAA 3WCXA 3NR8A 4B5FA 2DDRA 5J8NA 2JC5A 3TEBA 2JC4A 3GA6A 2DNJA 1HD7A 5J42A 3G3YA 3W3DB 4K6LF 5A7JA 5J3PA 3MTCA 4QHEA 4JG3A 4IEMA 2DDTA 4L1YA 4F1RA 1DNKA 2IMQX 1NTFA 3I46A 3G6SA 2J63A 4FPVA 1ATND 3I41A 5DFHA 4AWNA 5J3ZA 2ISIA 3G2CA 1I9YA 4B5GA 1SI6X 5DV4A 2EI9A 1AKOA 4QH9A 5INNA 5INOA 2O3CA 5A7IA 4PUQA 3G0AA 3N9VA 5DV2A 3NGOA 1DEWA 3W2XA 1VYBA 1WDUA 2XSWA 3FZIA 3CJCD 2V0RA 2DDSA 4QHDA 3G0RA 3G1KA 3G4TA 5INQA 4CMLA 5INPA 4F1HB 3DNIA 3NGNA 3G00A 3MPRA 3L1WA 1DE8A 2A40B 2V0SA 4F1IA 4B5MA 2A41B 4CMNA 3K55A 1Y21A 5EWTA 3U8UA 3G8VA 5INMA 1ZWXA 4B5JA 5INKA 1BIXA 4GYZA 3W2YA 2F2FB 5DG0A 1I9ZA 3I5VA 2O3HA 3G38A 1YJHA 5HT2A 2A3ZB 4RUWA 5CFGA 4C1RA 4F1HA 4L1ZA 3NGQA 1SR4B 4GZ1A 2UYRX 4A9CA 3G3CA 4L20A 3G91A 4B5IA 2F1NA 2D1KB 4GZ0A 4L21A 4FVAA 4B5HA 5DFIA 3I48A 2A42B
chains in the Genus database with same CATH topology
5INLA 4GEWA 4GZ2A 5J3SA 5CFEA 4LNDA 5DFJA 1DE9A 3G2DA 5DFFA 1E9NA 2VOAA 3WCXA 3NR8A 4B5FA 2DDRA 5J8NA 2JC5A 3TEBA 2JC4A 3GA6A 2DNJA 1HD7A 5J42A 3G3YA 3W3DB 4K6LF 5A7JA 5J3PA 3MTCA 4QHEA 4JG3A 4IEMA 2DDTA 4L1YA 4F1RA 1DNKA 2IMQX 1NTFA 3I46A 3G6SA 2J63A 4FPVA 1ATND 3I41A 5DFHA 4AWNA 5J3ZA 2ISIA 3G2CA 1I9YA 4B5GA 1SI6X 5DV4A 2EI9A 1AKOA 4QH9A 5INNA 5INOA 2O3CA 5A7IA 4PUQA 3G0AA 3N9VA 5DV2A 3NGOA 1DEWA 3W2XA 1VYBA 1WDUA 2XSWA 3FZIA 3CJCD 2V0RA 2DDSA 4QHDA 3G0RA 3G1KA 3G4TA 5INQA 4CMLA 5INPA 4F1HB 3DNIA 3NGNA 3G00A 3MPRA 3L1WA 1DE8A 2A40B 2V0SA 4F1IA 4B5MA 2A41B 4CMNA 3K55A 1Y21A 5EWTA 3U8UA 3G8VA 5INMA 1ZWXA 4B5JA 5INKA 1BIXA 4GYZA 3W2YA 2F2FB 5DG0A 1I9ZA 3I5VA 2O3HA 3G38A 1YJHA 5HT2A 2A3ZB 4RUWA 5CFGA 4C1RA 4F1HA 4L1ZA 3NGQA 1SR4B 4GZ1A 2UYRX 4A9CA 3G3CA 4L20A 3G91A 4B5IA 2F1NA 2D1KB 4GZ0A 4L21A 4FVAA 4B5HA 5DFIA 3I48A 2A42B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5INL A;  4GEW A;  4GZ2 A;  5J3S A;  5CFE A;  4LND A;  5DFJ A;  1DE9 A;  3G2D A;  5DFF A;  1E9N A;  2VOA A;  3WCX A;  3NR8 A;  4B5F A;  2DDR A;  5J8N A;  2JC5 A;  3TEB A;  2JC4 A;  3GA6 A;  2DNJ A;  1HD7 A;  5J42 A;  3G3Y A;  3W3D B;  4K6L F;  5A7J A;  5J3P A;  3MTC A;  4QHE A;  4JG3 A;  4IEM A;  2DDT A;  4L1Y A;  4F1R A;  1DNK A;  2IMQ X;  1NTF A;  3I46 A;  3G6S A;  2J63 A;  4FPV A;  1ATN D;  3I41 A;  5DFH A;  4AWN A;  5J3Z A;  2ISI A;  3G2C A;  1I9Y A;  4B5G A;  1SI6 X;  5DV4 A;  2EI9 A;  1AKO A;  4QH9 A;  5INN A;  5INO A;  2O3C A;  5A7I A;  4PUQ A;  3G0A A;  3N9V A;  5DV2 A;  3NGO A;  1DEW A;  3W2X A;  1VYB A;  1WDU A;  2XSW A;  3FZI A;  3CJC D;  2V0R A;  2DDS A;  4QHD A;  3G0R A;  3G1K A;  3G4T A;  5INQ A;  4CML A;  5INP A;  4F1H B;  3DNI A;  3NGN A;  3G00 A;  3MPR A;  3L1W A;  1DE8 A;  2A40 B;  2V0S A;  4F1I A;  4B5M A;  2A41 B;  4CMN A;  3K55 A;  1Y21 A;  5EWT A;  3U8U A;  3G8V A;  5INM A;  1ZWX A;  4B5J A;  5INK A;  1BIX A;  4GYZ A;  3W2Y A;  2F2F B;  5DG0 A;  1I9Z A;  3I5V A;  2O3H A;  3G38 A;  1YJH A;  5HT2 A;  2A3Z B;  4RUW A;  5CFG A;  4C1R A;  4F1H A;  4L1Z A;  3NGQ A;  1SR4 B;  4GZ1 A;  2UYR X;  4A9C A;  3G3C A;  4L20 A;  3G91 A;  4B5I A;  2F1N A;  2D1K B;  4GZ0 A;  4L21 A;  4FVA A;  4B5H A;  5DFI A;  3I48 A;  2A42 B; 
#chains in the Genus database with same CATH topology
 5INL A;  4GEW A;  4GZ2 A;  5J3S A;  5CFE A;  4LND A;  5DFJ A;  1DE9 A;  3G2D A;  5DFF A;  1E9N A;  2VOA A;  3WCX A;  3NR8 A;  4B5F A;  2DDR A;  5J8N A;  2JC5 A;  3TEB A;  2JC4 A;  3GA6 A;  2DNJ A;  1HD7 A;  5J42 A;  3G3Y A;  3W3D B;  4K6L F;  5A7J A;  5J3P A;  3MTC A;  4QHE A;  4JG3 A;  4IEM A;  2DDT A;  4L1Y A;  4F1R A;  1DNK A;  2IMQ X;  1NTF A;  3I46 A;  3G6S A;  2J63 A;  4FPV A;  1ATN D;  3I41 A;  5DFH A;  4AWN A;  5J3Z A;  2ISI A;  3G2C A;  1I9Y A;  4B5G A;  1SI6 X;  5DV4 A;  2EI9 A;  1AKO A;  4QH9 A;  5INN A;  5INO A;  2O3C A;  5A7I A;  4PUQ A;  3G0A A;  3N9V A;  5DV2 A;  3NGO A;  1DEW A;  3W2X A;  1VYB A;  1WDU A;  2XSW A;  3FZI A;  3CJC D;  2V0R A;  2DDS A;  4QHD A;  3G0R A;  3G1K A;  3G4T A;  5INQ A;  4CML A;  5INP A;  4F1H B;  3DNI A;  3NGN A;  3G00 A;  3MPR A;  3L1W A;  1DE8 A;  2A40 B;  2V0S A;  4F1I A;  4B5M A;  2A41 B;  4CMN A;  3K55 A;  1Y21 A;  5EWT A;  3U8U A;  3G8V A;  5INM A;  1ZWX A;  4B5J A;  5INK A;  1BIX A;  4GYZ A;  3W2Y A;  2F2F B;  5DG0 A;  1I9Z A;  3I5V A;  2O3H A;  3G38 A;  1YJH A;  5HT2 A;  2A3Z B;  4RUW A;  5CFG A;  4C1R A;  4F1H A;  4L1Z A;  3NGQ A;  1SR4 B;  4GZ1 A;  2UYR X;  4A9C A;  3G3C A;  4L20 A;  3G91 A;  4B5I A;  2F1N A;  2D1K B;  4GZ0 A;  4L21 A;  4FVA A;  4B5H A;  5DFI A;  3I48 A;  2A42 B; 
#chains in the Genus database with same CATH homology
 5INL A;  4GEW A;  4GZ2 A;  5J3S A;  5CFE A;  4LND A;  5DFJ A;  1DE9 A;  3G2D A;  5DFF A;  1E9N A;  2VOA A;  3WCX A;  3NR8 A;  4B5F A;  2DDR A;  5J8N A;  2JC5 A;  3TEB A;  2JC4 A;  3GA6 A;  2DNJ A;  1HD7 A;  5J42 A;  3G3Y A;  3W3D B;  4K6L F;  5A7J A;  5J3P A;  3MTC A;  4QHE A;  4JG3 A;  4IEM A;  2DDT A;  4L1Y A;  4F1R A;  1DNK A;  2IMQ X;  1NTF A;  3I46 A;  3G6S A;  2J63 A;  4FPV A;  1ATN D;  3I41 A;  5DFH A;  4AWN A;  5J3Z A;  2ISI A;  3G2C A;  1I9Y A;  4B5G A;  1SI6 X;  5DV4 A;  2EI9 A;  1AKO A;  4QH9 A;  5INN A;  5INO A;  2O3C A;  5A7I A;  4PUQ A;  3G0A A;  3N9V A;  5DV2 A;  3NGO A;  1DEW A;  3W2X A;  1VYB A;  1WDU A;  2XSW A;  3FZI A;  3CJC D;  2V0R A;  2DDS A;  4QHD A;  3G0R A;  3G1K A;  3G4T A;  5INQ A;  4CML A;  5INP A;  4F1H B;  3DNI A;  3NGN A;  3G00 A;  3MPR A;  3L1W A;  1DE8 A;  2A40 B;  2V0S A;  4F1I A;  4B5M A;  2A41 B;  4CMN A;  3K55 A;  1Y21 A;  5EWT A;  3U8U A;  3G8V A;  5INM A;  1ZWX A;  4B5J A;  5INK A;  1BIX A;  4GYZ A;  3W2Y A;  2F2F B;  5DG0 A;  1I9Z A;  3I5V A;  2O3H A;  3G38 A;  1YJH A;  5HT2 A;  2A3Z B;  4RUW A;  5CFG A;  4C1R A;  4F1H A;  4L1Z A;  3NGQ A;  1SR4 B;  4GZ1 A;  2UYR X;  4A9C A;  3G3C A;  4L20 A;  3G91 A;  4B5I A;  2F1N A;  2D1K B;  4GZ0 A;  4L21 A;  4FVA A;  4B5H A;  5DFI A;  3I48 A;  2A42 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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