2ETFA

Crystal structure of full length botulinum neurotoxin (type b) light chain
Total Genus 132
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
132
sequence length
437
structure length
431
Chain Sequence
PVTINNFNYNDPIDNNNIIMMEPPFARGTGRYYKAFKITDRIWIIPERYTFGYKPEDFNKSSGIFNRDVEYYDPDYLNTNDKKNIFLQTMIKLFNRIKSKPLGEKLLEMIINGIPYLGDRRVPLEEFNTNIASVTVNKLISNPGEVERKKGIFANLIIFGPGPVLNENETIDIGIQNHFASREGFGGIMQMKFCPEYVSVFNNVQENKGASIFNRRGYFSDPALILMHELIHVLHGLYGIKVDDLPIVPFMQSTDAIQAEELYTFGGQDPSIITPSTDKSIYDKVLQNFRGIVDRLNKVLVCISDPNININIYKNKFKDKYKFVEDSEGKYSIDVESFDKLYKSLMFGFTETNIAENYKIKTRASYFSDSLPPVKIKNLLDNEIYTIEEGFNISDKDMEKEYRGQNKAINKQAYEEISKEHLAVYKIQMCK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal structure of full length botulinum neurotoxin (Type B) light chain
rcsb
molecule tags Hydrolase
source organism Clostridium botulinum
molecule keywords Botulinum neurotoxin B light chain
total genus 132
structure length 431
sequence length 437
chains with identical sequence B
ec nomenclature ec 3.4.24.69: Bontoxilysin.
pdb deposition date 2005-10-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01742 Peptidase_M27 Clostridial neurotoxin zinc protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1240.10 Alpha Beta Alpha-Beta Complex Zincin-like Metalloproteases ("zincins"), catalytic domain like 2etfA00
2A97A 2ISEA 1F82A 3V0BB 2NP0A 4EL4A 1S0FA 3K3QB 3ZURA 1ZKWA 3QIXA 4KS6A 3DSEA 1G9BA 3V0AB 3FIEA 4J1LA 2XHLA 3BOKA 2G7KA 3NF3A 3C8BA 4ELCA 1E1HA 1ZL6A 3BOOA 1I1EA 3FFZA 3V0BA 3QW7A 2ILPA 4EJ5A 2G7QA 3QIYA 2QN0A 1S0BA 1XTGA 3DS9A 1ZN3A 2A8AA 2IMBA 1S0DA 2W2DA 2G7PA 2IMAA 3V0AA 4KUFA 3D3XA 3QJ0A 3DDAA 4KTXA 1ZL5A 3QW6A 4ZJXA 4ZKTB 3BONA 5BQNA 2G7NA 1S0CA 3QW5A 2NYYA 1EPWA 3QW8A 2FPQA 1YVGA 2ISHA 1T3CA 1S0EA 2ETFA 3BWIA 1G9AA 2ISGA 1G9CA 1ZB7A 3ZUSA 1S0GA 3DEBA 3BTAA 1Z7HA 1T3AA 3ZUQA 5BQMA 3C88A 1G9DA 4HEVA 3VUOA 3DDBA 3C89A 1F31A 2NZ9A 3QIZA 1XTFA 2IMCA 3C8AA 3FIIA 1ZKXA
chains in the Genus database with same CATH superfamily
2A97A 2ISEA 1F82A 3V0BB 2NP0A 4EL4A 1S0FA 3K3QB 3ZURA 1ZKWA 3QIXA 4KS6A 3DSEA 1G9BA 3V0AB 3FIEA 4J1LA 2XHLA 3BOKA 2G7KA 3NF3A 4QHFA 3C8BA 4ELCA 1E1HA 1ZL6A 3BOOA 4IL3A 1I1EA 3FFZA 3V0BA 3QW7A 2ILPA 4EJ5A 2G7QA 3QIYA 2QN0A 4AW6A 1S0BA 1XTGA 3DS9A 1ZN3A 2A8AA 2IMBA 1S0DA 2W2DA 2G7PA 2IMAA 3V0AA 4KUFA 3D3XA 3QJ0A 2YPTA 3DDAA 4KTXA 1ZL5A 3QW6A 4ZJXA 4ZKTB 3BONA 5BQNA 2EJQA 2G7NA 1S0CA 3QW5A 2NYYA 1EPWA 3QW8A 2FPQA 1YVGA 2ISHA 1T3CA 3CQBA 1S0EA 2ETFA 3BWIA 1G9AA 2ISGA 1G9CA 1ZB7A 3ZUSA 1S0GA 3DEBA 3BTAA 1Z7HA 1T3AA 3ZUQA 5BQMA 3C88A 1G9DA 4HEVA 4JIXA 3VUOA 3DDBA 3C89A 1F31A 2NZ9A 3QIZA 1XTFA 2IMCA 4JIUA 3C8AA 3FIIA 3E11A 1ZKXA
chains in the Genus database with same CATH topology
2A97A 2ISEA 1F82A 3V0BB 2NP0A 4EL4A 1S0FA 3K3QB 3ZURA 1ZKWA 3QIXA 4KS6A 3DSEA 1G9BA 3V0AB 3FIEA 4J1LA 2XHLA 3BOKA 2G7KA 3NF3A 3C8BA 4ELCA 1E1HA 1ZL6A 3BOOA 1I1EA 3FFZA 3V0BA 3QW7A 2ILPA 4EJ5A 2G7QA 3QIYA 2QN0A 1S0BA 1XTGA 3DS9A 1ZN3A 2A8AA 2IMBA 1S0DA 2W2DA 2G7PA 2IMAA 3V0AA 4KUFA 3D3XA 3QJ0A 3DDAA 4KTXA 1ZL5A 3QW6A 4ZJXA 4ZKTB 3BONA 5BQNA 2G7NA 1S0CA 3QW5A 2NYYA 1EPWA 3QW8A 2FPQA 1YVGA 2ISHA 1T3CA 1S0EA 2ETFA 3BWIA 1G9AA 2ISGA 1G9CA 1ZB7A 3ZUSA 1S0GA 3DEBA 3BTAA 1Z7HA 1T3AA 3ZUQA 5BQMA 3C88A 1G9DA 4HEVA 3VUOA 3DDBA 3C89A 1F31A 2NZ9A 3QIZA 1XTFA 2IMCA 3C8AA 3FIIA 1ZKXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2A97 A;  2ISE A;  1F82 A;  3V0B B;  2NP0 A;  4EL4 A;  1S0F A;  3K3Q B;  3ZUR A;  1ZKW A;  3QIX A;  4KS6 A;  3DSE A;  1G9B A;  3V0A B;  3FIE A;  4J1L A;  2XHL A;  3BOK A;  2G7K A;  3NF3 A;  3C8B A;  4ELC A;  1E1H A;  1ZL6 A;  3BOO A;  1I1E A;  3FFZ A;  3V0B A;  3QW7 A;  2ILP A;  4EJ5 A;  2G7Q A;  3QIY A;  2QN0 A;  1S0B A;  1XTG A;  3DS9 A;  1ZN3 A;  2A8A A;  2IMB A;  1S0D A;  2W2D A;  2G7P A;  2IMA A;  3V0A A;  4KUF A;  3D3X A;  3QJ0 A;  3DDA A;  4KTX A;  1ZL5 A;  3QW6 A;  4ZJX A;  4ZKT B;  3BON A;  5BQN A;  2G7N A;  1S0C A;  3QW5 A;  2NYY A;  1EPW A;  3QW8 A;  2FPQ A;  1YVG A;  2ISH A;  1T3C A;  1S0E A;  2ETF A;  3BWI A;  1G9A A;  2ISG A;  1G9C A;  1ZB7 A;  3ZUS A;  1S0G A;  3DEB A;  3BTA A;  1Z7H A;  1T3A A;  3ZUQ A;  5BQM A;  3C88 A;  1G9D A;  4HEV A;  3VUO A;  3DDB A;  3C89 A;  1F31 A;  2NZ9 A;  3QIZ A;  1XTF A;  2IMC A;  3C8A A;  3FII A;  1ZKX A; 
#chains in the Genus database with same CATH topology
 2A97 A;  2ISE A;  1F82 A;  3V0B B;  2NP0 A;  4EL4 A;  1S0F A;  3K3Q B;  3ZUR A;  1ZKW A;  3QIX A;  4KS6 A;  3DSE A;  1G9B A;  3V0A B;  3FIE A;  4J1L A;  2XHL A;  3BOK A;  2G7K A;  3NF3 A;  4QHF A;  3C8B A;  4ELC A;  1E1H A;  1ZL6 A;  3BOO A;  4IL3 A;  1I1E A;  3FFZ A;  3V0B A;  3QW7 A;  2ILP A;  4EJ5 A;  2G7Q A;  3QIY A;  2QN0 A;  4AW6 A;  1S0B A;  1XTG A;  3DS9 A;  1ZN3 A;  2A8A A;  2IMB A;  1S0D A;  2W2D A;  2G7P A;  2IMA A;  3V0A A;  4KUF A;  3D3X A;  3QJ0 A;  2YPT A;  3DDA A;  4KTX A;  1ZL5 A;  3QW6 A;  4ZJX A;  4ZKT B;  3BON A;  5BQN A;  2EJQ A;  2G7N A;  1S0C A;  3QW5 A;  2NYY A;  1EPW A;  3QW8 A;  2FPQ A;  1YVG A;  2ISH A;  1T3C A;  3CQB A;  1S0E A;  2ETF A;  3BWI A;  1G9A A;  2ISG A;  1G9C A;  1ZB7 A;  3ZUS A;  1S0G A;  3DEB A;  3BTA A;  1Z7H A;  1T3A A;  3ZUQ A;  5BQM A;  3C88 A;  1G9D A;  4HEV A;  4JIX A;  3VUO A;  3DDB A;  3C89 A;  1F31 A;  2NZ9 A;  3QIZ A;  1XTF A;  2IMC A;  4JIU A;  3C8A A;  3FII A;  3E11 A;  1ZKX A; 
#chains in the Genus database with same CATH homology
 2A97 A;  2ISE A;  1F82 A;  3V0B B;  2NP0 A;  4EL4 A;  1S0F A;  3K3Q B;  3ZUR A;  1ZKW A;  3QIX A;  4KS6 A;  3DSE A;  1G9B A;  3V0A B;  3FIE A;  4J1L A;  2XHL A;  3BOK A;  2G7K A;  3NF3 A;  3C8B A;  4ELC A;  1E1H A;  1ZL6 A;  3BOO A;  1I1E A;  3FFZ A;  3V0B A;  3QW7 A;  2ILP A;  4EJ5 A;  2G7Q A;  3QIY A;  2QN0 A;  1S0B A;  1XTG A;  3DS9 A;  1ZN3 A;  2A8A A;  2IMB A;  1S0D A;  2W2D A;  2G7P A;  2IMA A;  3V0A A;  4KUF A;  3D3X A;  3QJ0 A;  3DDA A;  4KTX A;  1ZL5 A;  3QW6 A;  4ZJX A;  4ZKT B;  3BON A;  5BQN A;  2G7N A;  1S0C A;  3QW5 A;  2NYY A;  1EPW A;  3QW8 A;  2FPQ A;  1YVG A;  2ISH A;  1T3C A;  1S0E A;  2ETF A;  3BWI A;  1G9A A;  2ISG A;  1G9C A;  1ZB7 A;  3ZUS A;  1S0G A;  3DEB A;  3BTA A;  1Z7H A;  1T3A A;  3ZUQ A;  5BQM A;  3C88 A;  1G9D A;  4HEV A;  3VUO A;  3DDB A;  3C89 A;  1F31 A;  2NZ9 A;  3QIZ A;  1XTF A;  2IMC A;  3C8A A;  3FII A;  1ZKX A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...