2JC4A

3'-5' exonuclease (nexo) from neisseria meningitidis
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
256
structure length
256
Chain Sequence
MKITTWNVNSLNVRLPQVQNLLADNPPDILVLQELKLDQDKFPAAALQMMGWHCVWSGQKTYNGVAIVSRSVPQDVHFGLPALPDDPQRRVIAATVSGVRVINVYCVNGEALDSPKFKYKEQWFAALTEFVRDEMTRHGKLVLLGDFNIAPADADCYDPEKWHEKIHCSSVERQWFQNLLDLGLTDSLRQVHPEGAFYTWFDYRGAMFQRKLGLRIDHILVSPAMAAALKDVRVDLETRALERPSDHAPVTAEFDW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Ap Endonuclease Paralogues with Distinct Activities in DNA Repair and Bacterial Pathogenesis.
pubmed doi rcsb
molecule tags Hydrolase
source organism Neisseria meningitidis
molecule keywords EXODEOXYRIBONUCLEASE III
total genus 91
structure length 256
sequence length 256
ec nomenclature ec 3.1.11.2: Exodeoxyribonuclease III.
pdb deposition date 2006-12-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 2jc4A00
3G00A 3G3CA 2DNJA 4L1ZA 3K55A 2UYRX 5INKA 2DDRA 5INOA 4QH9A 3NGNA 2JC4A 4L20A 4B5JA 4F1HA 2J63A 5EWTA 1DE9A 5J3PA 4F1IA 5DFHA 5DV4A 1ZWXA 1Y21A 1I9YA 4AWNA 3N9VA 3U8UA 1I9ZA 3G91A 4GYZA 2VOAA 3I48A 1DEWA 3W3DB 2A40B 5DFFA 5DFJA 5A7IA 5INPA 5DV2A 4B5HA 1E9NA 3NR8A 5J3SA 4CMNA 2O3HA 3FZIA 4IEMA 4L21A 4B5GA 5A7JA 3G0RA 3W2XA 5J42A 3G2DA 5DG0A 4K6LF 3G3YA 4F1RA 2A3ZB 4FPVA 1DE8A 2A41B 3G8VA 1AKOA 5INLA 3L1WA 1SI6X 4GEWA 4JG3A 2A42B 5J3ZA 5INQA 2DDSA 2ISIA 5J8NA 2F2FB 3NGQA 4L1YA 1HD7A 1NTFA 2IMQX 1SR4B 1VYBA 4QHEA 4LNDA 3G6SA 1WDUA 2XSWA 3G1KA 5INMA 3G0AA 2V0SA 2F1NA 2D1KB 2DDTA 3G2CA 3CJCD 3TEBA 1YJHA 2JC5A 4QHDA 4F1HB 5DFIA 4FVAA 4GZ2A 5CFEA 3G4TA 3WCXA 2O3CA 3DNIA 1ATND 4A9CA 3I41A 3NGOA 1BIXA 4PUQA 4GZ1A 3I5VA 3MTCA 4RUWA 3G38A 2EI9A 3W2YA 2V0RA 4CMLA 4C1RA 5CFGA 4GZ0A 5HT2A 4B5MA 5INNA 3I46A 3MPRA 4B5FA 4B5IA 1DNKA 3GA6A
chains in the Genus database with same CATH superfamily
3G00A 3G3CA 2DNJA 4L1ZA 3K55A 2UYRX 5INKA 2DDRA 5INOA 4QH9A 3NGNA 2JC4A 4L20A 4B5JA 4F1HA 2J63A 5EWTA 1DE9A 5J3PA 4F1IA 5DFHA 5DV4A 1ZWXA 1Y21A 1I9YA 4AWNA 3N9VA 3U8UA 1I9ZA 3G91A 4GYZA 2VOAA 3I48A 1DEWA 3W3DB 2A40B 5DFFA 5DFJA 5A7IA 5INPA 5DV2A 4B5HA 1E9NA 3NR8A 5J3SA 4CMNA 2O3HA 3FZIA 4IEMA 4L21A 4B5GA 5A7JA 3G0RA 3W2XA 5J42A 3G2DA 5DG0A 4K6LF 3G3YA 4F1RA 2A3ZB 4FPVA 1DE8A 2A41B 3G8VA 1AKOA 5INLA 3L1WA 1SI6X 4GEWA 4JG3A 2A42B 5J3ZA 5INQA 2DDSA 2ISIA 5J8NA 2F2FB 3NGQA 4L1YA 1HD7A 1NTFA 2IMQX 1SR4B 1VYBA 4QHEA 4LNDA 3G6SA 1WDUA 2XSWA 3G1KA 5INMA 3G0AA 2V0SA 2F1NA 2D1KB 2DDTA 3G2CA 3CJCD 3TEBA 1YJHA 2JC5A 4QHDA 4F1HB 5DFIA 4FVAA 4GZ2A 5CFEA 3G4TA 3WCXA 2O3CA 3DNIA 1ATND 4A9CA 3I41A 3NGOA 1BIXA 4PUQA 4GZ1A 3I5VA 3MTCA 4RUWA 3G38A 2EI9A 3W2YA 2V0RA 4CMLA 4C1RA 5CFGA 4GZ0A 5HT2A 4B5MA 5INNA 3I46A 3MPRA 4B5FA 4B5IA 1DNKA 3GA6A
chains in the Genus database with same CATH topology
3G00A 3G3CA 2DNJA 4L1ZA 3K55A 2UYRX 5INKA 2DDRA 5INOA 4QH9A 3NGNA 2JC4A 4L20A 4B5JA 4F1HA 2J63A 5EWTA 1DE9A 5J3PA 4F1IA 5DFHA 5DV4A 1ZWXA 1Y21A 1I9YA 4AWNA 3N9VA 3U8UA 1I9ZA 3G91A 4GYZA 2VOAA 3I48A 1DEWA 3W3DB 2A40B 5DFFA 5DFJA 5A7IA 5INPA 5DV2A 4B5HA 1E9NA 3NR8A 5J3SA 4CMNA 2O3HA 3FZIA 4IEMA 4L21A 4B5GA 5A7JA 3G0RA 3W2XA 5J42A 3G2DA 5DG0A 4K6LF 3G3YA 4F1RA 2A3ZB 4FPVA 1DE8A 2A41B 3G8VA 1AKOA 5INLA 3L1WA 1SI6X 4GEWA 4JG3A 2A42B 5J3ZA 5INQA 2DDSA 2ISIA 5J8NA 2F2FB 3NGQA 4L1YA 1HD7A 1NTFA 2IMQX 1SR4B 1VYBA 4QHEA 4LNDA 3G6SA 1WDUA 2XSWA 3G1KA 5INMA 3G0AA 2V0SA 2F1NA 2D1KB 2DDTA 3G2CA 3CJCD 3TEBA 1YJHA 2JC5A 4QHDA 4F1HB 5DFIA 4FVAA 4GZ2A 5CFEA 3G4TA 3WCXA 2O3CA 3DNIA 1ATND 4A9CA 3I41A 3NGOA 1BIXA 4PUQA 4GZ1A 3I5VA 3MTCA 4RUWA 3G38A 2EI9A 3W2YA 2V0RA 4CMLA 4C1RA 5CFGA 4GZ0A 5HT2A 4B5MA 5INNA 3I46A 3MPRA 4B5FA 4B5IA 1DNKA 3GA6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3G00 A;  3G3C A;  2DNJ A;  4L1Z A;  3K55 A;  2UYR X;  5INK A;  2DDR A;  5INO A;  4QH9 A;  3NGN A;  2JC4 A;  4L20 A;  4B5J A;  4F1H A;  2J63 A;  5EWT A;  1DE9 A;  5J3P A;  4F1I A;  5DFH A;  5DV4 A;  1ZWX A;  1Y21 A;  1I9Y A;  4AWN A;  3N9V A;  3U8U A;  1I9Z A;  3G91 A;  4GYZ A;  2VOA A;  3I48 A;  1DEW A;  3W3D B;  2A40 B;  5DFF A;  5DFJ A;  5A7I A;  5INP A;  5DV2 A;  4B5H A;  1E9N A;  3NR8 A;  5J3S A;  4CMN A;  2O3H A;  3FZI A;  4IEM A;  4L21 A;  4B5G A;  5A7J A;  3G0R A;  3W2X A;  5J42 A;  3G2D A;  5DG0 A;  4K6L F;  3G3Y A;  4F1R A;  2A3Z B;  4FPV A;  1DE8 A;  2A41 B;  3G8V A;  1AKO A;  5INL A;  3L1W A;  1SI6 X;  4GEW A;  4JG3 A;  2A42 B;  5J3Z A;  5INQ A;  2DDS A;  2ISI A;  5J8N A;  2F2F B;  3NGQ A;  4L1Y A;  1HD7 A;  1NTF A;  2IMQ X;  1SR4 B;  1VYB A;  4QHE A;  4LND A;  3G6S A;  1WDU A;  2XSW A;  3G1K A;  5INM A;  3G0A A;  2V0S A;  2F1N A;  2D1K B;  2DDT A;  3G2C A;  3CJC D;  3TEB A;  1YJH A;  2JC5 A;  4QHD A;  4F1H B;  5DFI A;  4FVA A;  4GZ2 A;  5CFE A;  3G4T A;  3WCX A;  2O3C A;  3DNI A;  1ATN D;  4A9C A;  3I41 A;  3NGO A;  1BIX A;  4PUQ A;  4GZ1 A;  3I5V A;  3MTC A;  4RUW A;  3G38 A;  2EI9 A;  3W2Y A;  2V0R A;  4CML A;  4C1R A;  5CFG A;  4GZ0 A;  5HT2 A;  4B5M A;  5INN A;  3I46 A;  3MPR A;  4B5F A;  4B5I A;  1DNK A;  3GA6 A; 
#chains in the Genus database with same CATH topology
 3G00 A;  3G3C A;  2DNJ A;  4L1Z A;  3K55 A;  2UYR X;  5INK A;  2DDR A;  5INO A;  4QH9 A;  3NGN A;  2JC4 A;  4L20 A;  4B5J A;  4F1H A;  2J63 A;  5EWT A;  1DE9 A;  5J3P A;  4F1I A;  5DFH A;  5DV4 A;  1ZWX A;  1Y21 A;  1I9Y A;  4AWN A;  3N9V A;  3U8U A;  1I9Z A;  3G91 A;  4GYZ A;  2VOA A;  3I48 A;  1DEW A;  3W3D B;  2A40 B;  5DFF A;  5DFJ A;  5A7I A;  5INP A;  5DV2 A;  4B5H A;  1E9N A;  3NR8 A;  5J3S A;  4CMN A;  2O3H A;  3FZI A;  4IEM A;  4L21 A;  4B5G A;  5A7J A;  3G0R A;  3W2X A;  5J42 A;  3G2D A;  5DG0 A;  4K6L F;  3G3Y A;  4F1R A;  2A3Z B;  4FPV A;  1DE8 A;  2A41 B;  3G8V A;  1AKO A;  5INL A;  3L1W A;  1SI6 X;  4GEW A;  4JG3 A;  2A42 B;  5J3Z A;  5INQ A;  2DDS A;  2ISI A;  5J8N A;  2F2F B;  3NGQ A;  4L1Y A;  1HD7 A;  1NTF A;  2IMQ X;  1SR4 B;  1VYB A;  4QHE A;  4LND A;  3G6S A;  1WDU A;  2XSW A;  3G1K A;  5INM A;  3G0A A;  2V0S A;  2F1N A;  2D1K B;  2DDT A;  3G2C A;  3CJC D;  3TEB A;  1YJH A;  2JC5 A;  4QHD A;  4F1H B;  5DFI A;  4FVA A;  4GZ2 A;  5CFE A;  3G4T A;  3WCX A;  2O3C A;  3DNI A;  1ATN D;  4A9C A;  3I41 A;  3NGO A;  1BIX A;  4PUQ A;  4GZ1 A;  3I5V A;  3MTC A;  4RUW A;  3G38 A;  2EI9 A;  3W2Y A;  2V0R A;  4CML A;  4C1R A;  5CFG A;  4GZ0 A;  5HT2 A;  4B5M A;  5INN A;  3I46 A;  3MPR A;  4B5F A;  4B5I A;  1DNK A;  3GA6 A; 
#chains in the Genus database with same CATH homology
 3G00 A;  3G3C A;  2DNJ A;  4L1Z A;  3K55 A;  2UYR X;  5INK A;  2DDR A;  5INO A;  4QH9 A;  3NGN A;  2JC4 A;  4L20 A;  4B5J A;  4F1H A;  2J63 A;  5EWT A;  1DE9 A;  5J3P A;  4F1I A;  5DFH A;  5DV4 A;  1ZWX A;  1Y21 A;  1I9Y A;  4AWN A;  3N9V A;  3U8U A;  1I9Z A;  3G91 A;  4GYZ A;  2VOA A;  3I48 A;  1DEW A;  3W3D B;  2A40 B;  5DFF A;  5DFJ A;  5A7I A;  5INP A;  5DV2 A;  4B5H A;  1E9N A;  3NR8 A;  5J3S A;  4CMN A;  2O3H A;  3FZI A;  4IEM A;  4L21 A;  4B5G A;  5A7J A;  3G0R A;  3W2X A;  5J42 A;  3G2D A;  5DG0 A;  4K6L F;  3G3Y A;  4F1R A;  2A3Z B;  4FPV A;  1DE8 A;  2A41 B;  3G8V A;  1AKO A;  5INL A;  3L1W A;  1SI6 X;  4GEW A;  4JG3 A;  2A42 B;  5J3Z A;  5INQ A;  2DDS A;  2ISI A;  5J8N A;  2F2F B;  3NGQ A;  4L1Y A;  1HD7 A;  1NTF A;  2IMQ X;  1SR4 B;  1VYB A;  4QHE A;  4LND A;  3G6S A;  1WDU A;  2XSW A;  3G1K A;  5INM A;  3G0A A;  2V0S A;  2F1N A;  2D1K B;  2DDT A;  3G2C A;  3CJC D;  3TEB A;  1YJH A;  2JC5 A;  4QHD A;  4F1H B;  5DFI A;  4FVA A;  4GZ2 A;  5CFE A;  3G4T A;  3WCX A;  2O3C A;  3DNI A;  1ATN D;  4A9C A;  3I41 A;  3NGO A;  1BIX A;  4PUQ A;  4GZ1 A;  3I5V A;  3MTC A;  4RUW A;  3G38 A;  2EI9 A;  3W2Y A;  2V0R A;  4CML A;  4C1R A;  5CFG A;  4GZ0 A;  5HT2 A;  4B5M A;  5INN A;  3I46 A;  3MPR A;  4B5F A;  4B5I A;  1DNK A;  3GA6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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