2O3CA

Crystal structure of zebrafish ape
Total Genus 93
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
93
sequence length
276
structure length
276
Chain Sequence
PILYEDPPEKLTSKDGRAANMKITSWNVDGLRAWVKKNGLDWVRKEDPDILCLQETKCAEKALPADITAMPEYPHKYWAGSEDKEGYSGVAMLCKTEPLNVTYGIGKEEHDKEGRVITAEFPDFFLVTAYVPNASRGLVRLDYRKTWDVDFRAYLCGLDARKPLVLCGDLNVAHQEIDLKNPKGNRKNAGFTPEEREGFTQLLEAGFTDSFRELYPDQAYAYTFWTYMMNARSKNVGWRLDYFVLSSALLPGLCDSKIRNTAMGSDHCPITLFLAV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease
pubmed doi rcsb
molecule tags Dna binding protein
source organism Danio rerio
molecule keywords APEX nuclease 1
total genus 93
structure length 276
sequence length 276
chains with identical sequence B, C
ec nomenclature ec 4.2.99.18: DNA-(apurinic or apyrimidinic site) lyase.
pdb deposition date 2006-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 2o3cA00
4QH9A 5A7IA 1NTFA 3W3DB 1E9NA 4IEMA 5DV2A 2EI9A 1SR4B 3I48A 4F1IA 4GZ2A 5DFHA 5HT2A 2IMQX 2O3CA 3DNIA 4GEWA 5J42A 4CMNA 4B5GA 5DG0A 1DE9A 2A41B 2ISIA 1YJHA 2V0RA 4QHEA 4LNDA 5INQA 2O3HA 4AWNA 2VOAA 2XSWA 1ZWXA 3G0AA 4QHDA 5J8NA 4GZ0A 4L21A 3G2CA 3MTCA 4B5FA 4GYZA 3GA6A 4GZ1A 2A42B 3G6SA 1VYBA 4FVAA 5A7JA 3G8VA 4B5JA 2A3ZB 1Y21A 3NGOA 2UYRX 2DNJA 5INNA 5EWTA 4F1HB 1I9YA 3U8UA 5J3PA 4F1HA 5CFEA 3W2XA 4CMLA 1SI6X 3CJCD 3G1KA 4A9CA 4B5IA 4FPVA 5J3SA 2F1NA 3W2YA 3L1WA 2J63A 1AKOA 1WDUA 4F1RA 3K55A 3I46A 3G4TA 3G00A 1ATND 3G38A 2JC4A 4K6LF 3G2DA 5CFGA 4RUWA 5INPA 4L1YA 5INOA 3G91A 3MPRA 1DEWA 5INLA 3FZIA 3NGNA 3I41A 3TEBA 1DE8A 5INKA 3I5VA 2DDRA 5J3ZA 1I9ZA 5DFFA 5DV4A 5DFJA 4JG3A 1DNKA 3N9VA 4L1ZA 2V0SA 2D1KB 4C1RA 2F2FB 1HD7A 4L20A 3G3YA 3NR8A 4PUQA 2JC5A 3NGQA 4B5HA 3G3CA 2DDSA 5INMA 3WCXA 5DFIA 2A40B 1BIXA 3G0RA 4B5MA 2DDTA
chains in the Genus database with same CATH superfamily
4QH9A 5A7IA 1NTFA 3W3DB 1E9NA 4IEMA 5DV2A 2EI9A 1SR4B 3I48A 4F1IA 4GZ2A 5DFHA 5HT2A 2IMQX 2O3CA 3DNIA 4GEWA 5J42A 4CMNA 4B5GA 5DG0A 1DE9A 2A41B 2ISIA 1YJHA 2V0RA 4QHEA 4LNDA 5INQA 2O3HA 4AWNA 2VOAA 2XSWA 1ZWXA 3G0AA 4QHDA 5J8NA 4GZ0A 4L21A 3G2CA 3MTCA 4B5FA 4GYZA 3GA6A 4GZ1A 2A42B 3G6SA 1VYBA 4FVAA 5A7JA 3G8VA 4B5JA 2A3ZB 1Y21A 3NGOA 2UYRX 2DNJA 5INNA 5EWTA 4F1HB 1I9YA 3U8UA 5J3PA 4F1HA 5CFEA 3W2XA 4CMLA 1SI6X 3CJCD 3G1KA 4A9CA 4B5IA 4FPVA 5J3SA 2F1NA 3W2YA 3L1WA 2J63A 1AKOA 1WDUA 4F1RA 3K55A 3I46A 3G4TA 3G00A 1ATND 3G38A 2JC4A 4K6LF 3G2DA 5CFGA 4RUWA 5INPA 4L1YA 5INOA 3G91A 3MPRA 1DEWA 5INLA 3FZIA 3NGNA 3I41A 3TEBA 1DE8A 5INKA 3I5VA 2DDRA 5J3ZA 1I9ZA 5DFFA 5DV4A 5DFJA 4JG3A 1DNKA 3N9VA 4L1ZA 2V0SA 2D1KB 4C1RA 2F2FB 1HD7A 4L20A 3G3YA 3NR8A 4PUQA 2JC5A 3NGQA 4B5HA 3G3CA 2DDSA 5INMA 3WCXA 5DFIA 2A40B 1BIXA 3G0RA 4B5MA 2DDTA
chains in the Genus database with same CATH topology
4QH9A 5A7IA 1NTFA 3W3DB 1E9NA 4IEMA 5DV2A 2EI9A 1SR4B 3I48A 4F1IA 4GZ2A 5DFHA 5HT2A 2IMQX 2O3CA 3DNIA 4GEWA 5J42A 4CMNA 4B5GA 5DG0A 1DE9A 2A41B 2ISIA 1YJHA 2V0RA 4QHEA 4LNDA 5INQA 2O3HA 4AWNA 2VOAA 2XSWA 1ZWXA 3G0AA 4QHDA 5J8NA 4GZ0A 4L21A 3G2CA 3MTCA 4B5FA 4GYZA 3GA6A 4GZ1A 2A42B 3G6SA 1VYBA 4FVAA 5A7JA 3G8VA 4B5JA 2A3ZB 1Y21A 3NGOA 2UYRX 2DNJA 5INNA 5EWTA 4F1HB 1I9YA 3U8UA 5J3PA 4F1HA 5CFEA 3W2XA 4CMLA 1SI6X 3CJCD 3G1KA 4A9CA 4B5IA 4FPVA 5J3SA 2F1NA 3W2YA 3L1WA 2J63A 1AKOA 1WDUA 4F1RA 3K55A 3I46A 3G4TA 3G00A 1ATND 3G38A 2JC4A 4K6LF 3G2DA 5CFGA 4RUWA 5INPA 4L1YA 5INOA 3G91A 3MPRA 1DEWA 5INLA 3FZIA 3NGNA 3I41A 3TEBA 1DE8A 5INKA 3I5VA 2DDRA 5J3ZA 1I9ZA 5DFFA 5DV4A 5DFJA 4JG3A 1DNKA 3N9VA 4L1ZA 2V0SA 2D1KB 4C1RA 2F2FB 1HD7A 4L20A 3G3YA 3NR8A 4PUQA 2JC5A 3NGQA 4B5HA 3G3CA 2DDSA 5INMA 3WCXA 5DFIA 2A40B 1BIXA 3G0RA 4B5MA 2DDTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4QH9 A;  5A7I A;  1NTF A;  3W3D B;  1E9N A;  4IEM A;  5DV2 A;  2EI9 A;  1SR4 B;  3I48 A;  4F1I A;  4GZ2 A;  5DFH A;  5HT2 A;  2IMQ X;  2O3C A;  3DNI A;  4GEW A;  5J42 A;  4CMN A;  4B5G A;  5DG0 A;  1DE9 A;  2A41 B;  2ISI A;  1YJH A;  2V0R A;  4QHE A;  4LND A;  5INQ A;  2O3H A;  4AWN A;  2VOA A;  2XSW A;  1ZWX A;  3G0A A;  4QHD A;  5J8N A;  4GZ0 A;  4L21 A;  3G2C A;  3MTC A;  4B5F A;  4GYZ A;  3GA6 A;  4GZ1 A;  2A42 B;  3G6S A;  1VYB A;  4FVA A;  5A7J A;  3G8V A;  4B5J A;  2A3Z B;  1Y21 A;  3NGO A;  2UYR X;  2DNJ A;  5INN A;  5EWT A;  4F1H B;  1I9Y A;  3U8U A;  5J3P A;  4F1H A;  5CFE A;  3W2X A;  4CML A;  1SI6 X;  3CJC D;  3G1K A;  4A9C A;  4B5I A;  4FPV A;  5J3S A;  2F1N A;  3W2Y A;  3L1W A;  2J63 A;  1AKO A;  1WDU A;  4F1R A;  3K55 A;  3I46 A;  3G4T A;  3G00 A;  1ATN D;  3G38 A;  2JC4 A;  4K6L F;  3G2D A;  5CFG A;  4RUW A;  5INP A;  4L1Y A;  5INO A;  3G91 A;  3MPR A;  1DEW A;  5INL A;  3FZI A;  3NGN A;  3I41 A;  3TEB A;  1DE8 A;  5INK A;  3I5V A;  2DDR A;  5J3Z A;  1I9Z A;  5DFF A;  5DV4 A;  5DFJ A;  4JG3 A;  1DNK A;  3N9V A;  4L1Z A;  2V0S A;  2D1K B;  4C1R A;  2F2F B;  1HD7 A;  4L20 A;  3G3Y A;  3NR8 A;  4PUQ A;  2JC5 A;  3NGQ A;  4B5H A;  3G3C A;  2DDS A;  5INM A;  3WCX A;  5DFI A;  2A40 B;  1BIX A;  3G0R A;  4B5M A;  2DDT A; 
#chains in the Genus database with same CATH topology
 4QH9 A;  5A7I A;  1NTF A;  3W3D B;  1E9N A;  4IEM A;  5DV2 A;  2EI9 A;  1SR4 B;  3I48 A;  4F1I A;  4GZ2 A;  5DFH A;  5HT2 A;  2IMQ X;  2O3C A;  3DNI A;  4GEW A;  5J42 A;  4CMN A;  4B5G A;  5DG0 A;  1DE9 A;  2A41 B;  2ISI A;  1YJH A;  2V0R A;  4QHE A;  4LND A;  5INQ A;  2O3H A;  4AWN A;  2VOA A;  2XSW A;  1ZWX A;  3G0A A;  4QHD A;  5J8N A;  4GZ0 A;  4L21 A;  3G2C A;  3MTC A;  4B5F A;  4GYZ A;  3GA6 A;  4GZ1 A;  2A42 B;  3G6S A;  1VYB A;  4FVA A;  5A7J A;  3G8V A;  4B5J A;  2A3Z B;  1Y21 A;  3NGO A;  2UYR X;  2DNJ A;  5INN A;  5EWT A;  4F1H B;  1I9Y A;  3U8U A;  5J3P A;  4F1H A;  5CFE A;  3W2X A;  4CML A;  1SI6 X;  3CJC D;  3G1K A;  4A9C A;  4B5I A;  4FPV A;  5J3S A;  2F1N A;  3W2Y A;  3L1W A;  2J63 A;  1AKO A;  1WDU A;  4F1R A;  3K55 A;  3I46 A;  3G4T A;  3G00 A;  1ATN D;  3G38 A;  2JC4 A;  4K6L F;  3G2D A;  5CFG A;  4RUW A;  5INP A;  4L1Y A;  5INO A;  3G91 A;  3MPR A;  1DEW A;  5INL A;  3FZI A;  3NGN A;  3I41 A;  3TEB A;  1DE8 A;  5INK A;  3I5V A;  2DDR A;  5J3Z A;  1I9Z A;  5DFF A;  5DV4 A;  5DFJ A;  4JG3 A;  1DNK A;  3N9V A;  4L1Z A;  2V0S A;  2D1K B;  4C1R A;  2F2F B;  1HD7 A;  4L20 A;  3G3Y A;  3NR8 A;  4PUQ A;  2JC5 A;  3NGQ A;  4B5H A;  3G3C A;  2DDS A;  5INM A;  3WCX A;  5DFI A;  2A40 B;  1BIX A;  3G0R A;  4B5M A;  2DDT A; 
#chains in the Genus database with same CATH homology
 4QH9 A;  5A7I A;  1NTF A;  3W3D B;  1E9N A;  4IEM A;  5DV2 A;  2EI9 A;  1SR4 B;  3I48 A;  4F1I A;  4GZ2 A;  5DFH A;  5HT2 A;  2IMQ X;  2O3C A;  3DNI A;  4GEW A;  5J42 A;  4CMN A;  4B5G A;  5DG0 A;  1DE9 A;  2A41 B;  2ISI A;  1YJH A;  2V0R A;  4QHE A;  4LND A;  5INQ A;  2O3H A;  4AWN A;  2VOA A;  2XSW A;  1ZWX A;  3G0A A;  4QHD A;  5J8N A;  4GZ0 A;  4L21 A;  3G2C A;  3MTC A;  4B5F A;  4GYZ A;  3GA6 A;  4GZ1 A;  2A42 B;  3G6S A;  1VYB A;  4FVA A;  5A7J A;  3G8V A;  4B5J A;  2A3Z B;  1Y21 A;  3NGO A;  2UYR X;  2DNJ A;  5INN A;  5EWT A;  4F1H B;  1I9Y A;  3U8U A;  5J3P A;  4F1H A;  5CFE A;  3W2X A;  4CML A;  1SI6 X;  3CJC D;  3G1K A;  4A9C A;  4B5I A;  4FPV A;  5J3S A;  2F1N A;  3W2Y A;  3L1W A;  2J63 A;  1AKO A;  1WDU A;  4F1R A;  3K55 A;  3I46 A;  3G4T A;  3G00 A;  1ATN D;  3G38 A;  2JC4 A;  4K6L F;  3G2D A;  5CFG A;  4RUW A;  5INP A;  4L1Y A;  5INO A;  3G91 A;  3MPR A;  1DEW A;  5INL A;  3FZI A;  3NGN A;  3I41 A;  3TEB A;  1DE8 A;  5INK A;  3I5V A;  2DDR A;  5J3Z A;  1I9Z A;  5DFF A;  5DV4 A;  5DFJ A;  4JG3 A;  1DNK A;  3N9V A;  4L1Z A;  2V0S A;  2D1K B;  4C1R A;  2F2F B;  1HD7 A;  4L20 A;  3G3Y A;  3NR8 A;  4PUQ A;  2JC5 A;  3NGQ A;  4B5H A;  3G3C A;  2DDS A;  5INM A;  3WCX A;  5DFI A;  2A40 B;  1BIX A;  3G0R A;  4B5M A;  2DDT A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...