2XSWA

Crystal structure of human inpp5e
Total Genus 112
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
112
sequence length
343
structure length
340
Chain Sequence
GALLGADELARYFPDRNVALFVATWNMQGQKELPPSLDEFLLPAEADYAQDLYVIGVQEGCSDRREWETRLQETLGPHYVLLSSAAHGVLYMSLFIRRDLIWFCSEVECSTVTTRIVSQIKTKGALGISFTFFGTSFLFITSHFTSGDGKVAERLLDYTRTVQALVLPRNVPDTNPYRSSAADVTTRFDEVFWFGDFNFRLSGGRTVVDALLCVVDVPALLQHDQLIREMRKGSIFKGFQEPDIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLYRSRHKGDICPVSYSSCPGIKTSDHRPVYGLFRVKVRPGRDNIPLAAGKFDRELYLLGIKRRISA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Human Inpp5E
rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords 72 KDA INOSITOL POLYPHOSPHATE 5-PHOSPHATASE
total genus 112
structure length 340
sequence length 343
chains with identical sequence B
ec nomenclature ec 3.1.3.36: Phosphoinositide 5-phosphatase.
pdb deposition date 2010-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 2xswA00
3MTCA 4L1YA 1DNKA 2ISIA 2JC5A 4L20A 3TEBA 5A7JA 4B5MA 5A7IA 4A9CA 3G8VA 4IEMA 1VYBA 4GZ2A 2DDSA 5HT2A 4B5HA 5DFHA 4RUWA 2D1KB 3G00A 3G1KA 3G91A 4L21A 3W2XA 3G3YA 1I9ZA 3DNIA 1SI6X 4QH9A 5INOA 5INLA 2V0RA 3G3CA 1Y21A 5CFEA 4B5GA 3I5VA 5INMA 2A3ZB 2J63A 4K6LF 5J3ZA 1E9NA 4GEWA 5J8NA 5DFJA 1YJHA 4F1HA 3G2DA 2JC4A 2V0SA 2DDRA 2A41B 1I9YA 3N9VA 4B5JA 3G6SA 2F2FB 2EI9A 1AKOA 4L1ZA 5DFFA 3I48A 5INPA 2VOAA 5DV2A 4PUQA 3I41A 5DFIA 2A40B 3W2YA 5INNA 4QHEA 1DE9A 3NGQA 3NGOA 4FVAA 3G4TA 4C1RA 4FPVA 2DNJA 3L1WA 5DG0A 2XSWA 4JG3A 2O3CA 3U8UA 5J3SA 5INQA 3K55A 1HD7A 2UYRX 3I46A 3NR8A 4AWNA 1SR4B 4GZ0A 5J3PA 1DE8A 3NGNA 5CFGA 4QHDA 2O3HA 3CJCD 5J42A 4LNDA 4B5IA 1ZWXA 4GZ1A 4F1RA 1WDUA 3W3DB 4B5FA 3WCXA 1ATND 1NTFA 2DDTA 4F1IA 4CMLA 5EWTA 4F1HB 1BIXA 3G2CA 4CMNA 1DEWA 2F1NA 3G0RA 5DV4A 3MPRA 5INKA 2IMQX 3G0AA 3GA6A 2A42B 3G38A 4GYZA 3FZIA
chains in the Genus database with same CATH superfamily
3MTCA 4L1YA 1DNKA 2ISIA 2JC5A 4L20A 3TEBA 5A7JA 4B5MA 5A7IA 4A9CA 3G8VA 4IEMA 1VYBA 4GZ2A 2DDSA 5HT2A 4B5HA 5DFHA 4RUWA 2D1KB 3G00A 3G1KA 3G91A 4L21A 3W2XA 3G3YA 1I9ZA 3DNIA 1SI6X 4QH9A 5INOA 5INLA 2V0RA 3G3CA 1Y21A 5CFEA 4B5GA 3I5VA 5INMA 2A3ZB 2J63A 4K6LF 5J3ZA 1E9NA 4GEWA 5J8NA 5DFJA 1YJHA 4F1HA 3G2DA 2JC4A 2V0SA 2DDRA 2A41B 1I9YA 3N9VA 4B5JA 3G6SA 2F2FB 2EI9A 1AKOA 4L1ZA 5DFFA 3I48A 5INPA 2VOAA 5DV2A 4PUQA 3I41A 5DFIA 2A40B 3W2YA 5INNA 4QHEA 1DE9A 3NGQA 3NGOA 4FVAA 3G4TA 4C1RA 4FPVA 2DNJA 3L1WA 5DG0A 2XSWA 4JG3A 2O3CA 3U8UA 5J3SA 5INQA 3K55A 1HD7A 2UYRX 3I46A 3NR8A 4AWNA 1SR4B 4GZ0A 5J3PA 1DE8A 3NGNA 5CFGA 4QHDA 2O3HA 3CJCD 5J42A 4LNDA 4B5IA 1ZWXA 4GZ1A 4F1RA 1WDUA 3W3DB 4B5FA 3WCXA 1ATND 1NTFA 2DDTA 4F1IA 4CMLA 5EWTA 4F1HB 1BIXA 3G2CA 4CMNA 1DEWA 2F1NA 3G0RA 5DV4A 3MPRA 5INKA 2IMQX 3G0AA 3GA6A 2A42B 3G38A 4GYZA 3FZIA
chains in the Genus database with same CATH topology
3MTCA 4L1YA 1DNKA 2ISIA 2JC5A 4L20A 3TEBA 5A7JA 4B5MA 5A7IA 4A9CA 3G8VA 4IEMA 1VYBA 4GZ2A 2DDSA 5HT2A 4B5HA 5DFHA 4RUWA 2D1KB 3G00A 3G1KA 3G91A 4L21A 3W2XA 3G3YA 1I9ZA 3DNIA 1SI6X 4QH9A 5INOA 5INLA 2V0RA 3G3CA 1Y21A 5CFEA 4B5GA 3I5VA 5INMA 2A3ZB 2J63A 4K6LF 5J3ZA 1E9NA 4GEWA 5J8NA 5DFJA 1YJHA 4F1HA 3G2DA 2JC4A 2V0SA 2DDRA 2A41B 1I9YA 3N9VA 4B5JA 3G6SA 2F2FB 2EI9A 1AKOA 4L1ZA 5DFFA 3I48A 5INPA 2VOAA 5DV2A 4PUQA 3I41A 5DFIA 2A40B 3W2YA 5INNA 4QHEA 1DE9A 3NGQA 3NGOA 4FVAA 3G4TA 4C1RA 4FPVA 2DNJA 3L1WA 5DG0A 2XSWA 4JG3A 2O3CA 3U8UA 5J3SA 5INQA 3K55A 1HD7A 2UYRX 3I46A 3NR8A 4AWNA 1SR4B 4GZ0A 5J3PA 1DE8A 3NGNA 5CFGA 4QHDA 2O3HA 3CJCD 5J42A 4LNDA 4B5IA 1ZWXA 4GZ1A 4F1RA 1WDUA 3W3DB 4B5FA 3WCXA 1ATND 1NTFA 2DDTA 4F1IA 4CMLA 5EWTA 4F1HB 1BIXA 3G2CA 4CMNA 1DEWA 2F1NA 3G0RA 5DV4A 3MPRA 5INKA 2IMQX 3G0AA 3GA6A 2A42B 3G38A 4GYZA 3FZIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3MTC A;  4L1Y A;  1DNK A;  2ISI A;  2JC5 A;  4L20 A;  3TEB A;  5A7J A;  4B5M A;  5A7I A;  4A9C A;  3G8V A;  4IEM A;  1VYB A;  4GZ2 A;  2DDS A;  5HT2 A;  4B5H A;  5DFH A;  4RUW A;  2D1K B;  3G00 A;  3G1K A;  3G91 A;  4L21 A;  3W2X A;  3G3Y A;  1I9Z A;  3DNI A;  1SI6 X;  4QH9 A;  5INO A;  5INL A;  2V0R A;  3G3C A;  1Y21 A;  5CFE A;  4B5G A;  3I5V A;  5INM A;  2A3Z B;  2J63 A;  4K6L F;  5J3Z A;  1E9N A;  4GEW A;  5J8N A;  5DFJ A;  1YJH A;  4F1H A;  3G2D A;  2JC4 A;  2V0S A;  2DDR A;  2A41 B;  1I9Y A;  3N9V A;  4B5J A;  3G6S A;  2F2F B;  2EI9 A;  1AKO A;  4L1Z A;  5DFF A;  3I48 A;  5INP A;  2VOA A;  5DV2 A;  4PUQ A;  3I41 A;  5DFI A;  2A40 B;  3W2Y A;  5INN A;  4QHE A;  1DE9 A;  3NGQ A;  3NGO A;  4FVA A;  3G4T A;  4C1R A;  4FPV A;  2DNJ A;  3L1W A;  5DG0 A;  2XSW A;  4JG3 A;  2O3C A;  3U8U A;  5J3S A;  5INQ A;  3K55 A;  1HD7 A;  2UYR X;  3I46 A;  3NR8 A;  4AWN A;  1SR4 B;  4GZ0 A;  5J3P A;  1DE8 A;  3NGN A;  5CFG A;  4QHD A;  2O3H A;  3CJC D;  5J42 A;  4LND A;  4B5I A;  1ZWX A;  4GZ1 A;  4F1R A;  1WDU A;  3W3D B;  4B5F A;  3WCX A;  1ATN D;  1NTF A;  2DDT A;  4F1I A;  4CML A;  5EWT A;  4F1H B;  1BIX A;  3G2C A;  4CMN A;  1DEW A;  2F1N A;  3G0R A;  5DV4 A;  3MPR A;  5INK A;  2IMQ X;  3G0A A;  3GA6 A;  2A42 B;  3G38 A;  4GYZ A;  3FZI A; 
#chains in the Genus database with same CATH topology
 3MTC A;  4L1Y A;  1DNK A;  2ISI A;  2JC5 A;  4L20 A;  3TEB A;  5A7J A;  4B5M A;  5A7I A;  4A9C A;  3G8V A;  4IEM A;  1VYB A;  4GZ2 A;  2DDS A;  5HT2 A;  4B5H A;  5DFH A;  4RUW A;  2D1K B;  3G00 A;  3G1K A;  3G91 A;  4L21 A;  3W2X A;  3G3Y A;  1I9Z A;  3DNI A;  1SI6 X;  4QH9 A;  5INO A;  5INL A;  2V0R A;  3G3C A;  1Y21 A;  5CFE A;  4B5G A;  3I5V A;  5INM A;  2A3Z B;  2J63 A;  4K6L F;  5J3Z A;  1E9N A;  4GEW A;  5J8N A;  5DFJ A;  1YJH A;  4F1H A;  3G2D A;  2JC4 A;  2V0S A;  2DDR A;  2A41 B;  1I9Y A;  3N9V A;  4B5J A;  3G6S A;  2F2F B;  2EI9 A;  1AKO A;  4L1Z A;  5DFF A;  3I48 A;  5INP A;  2VOA A;  5DV2 A;  4PUQ A;  3I41 A;  5DFI A;  2A40 B;  3W2Y A;  5INN A;  4QHE A;  1DE9 A;  3NGQ A;  3NGO A;  4FVA A;  3G4T A;  4C1R A;  4FPV A;  2DNJ A;  3L1W A;  5DG0 A;  2XSW A;  4JG3 A;  2O3C A;  3U8U A;  5J3S A;  5INQ A;  3K55 A;  1HD7 A;  2UYR X;  3I46 A;  3NR8 A;  4AWN A;  1SR4 B;  4GZ0 A;  5J3P A;  1DE8 A;  3NGN A;  5CFG A;  4QHD A;  2O3H A;  3CJC D;  5J42 A;  4LND A;  4B5I A;  1ZWX A;  4GZ1 A;  4F1R A;  1WDU A;  3W3D B;  4B5F A;  3WCX A;  1ATN D;  1NTF A;  2DDT A;  4F1I A;  4CML A;  5EWT A;  4F1H B;  1BIX A;  3G2C A;  4CMN A;  1DEW A;  2F1N A;  3G0R A;  5DV4 A;  3MPR A;  5INK A;  2IMQ X;  3G0A A;  3GA6 A;  2A42 B;  3G38 A;  4GYZ A;  3FZI A; 
#chains in the Genus database with same CATH homology
 3MTC A;  4L1Y A;  1DNK A;  2ISI A;  2JC5 A;  4L20 A;  3TEB A;  5A7J A;  4B5M A;  5A7I A;  4A9C A;  3G8V A;  4IEM A;  1VYB A;  4GZ2 A;  2DDS A;  5HT2 A;  4B5H A;  5DFH A;  4RUW A;  2D1K B;  3G00 A;  3G1K A;  3G91 A;  4L21 A;  3W2X A;  3G3Y A;  1I9Z A;  3DNI A;  1SI6 X;  4QH9 A;  5INO A;  5INL A;  2V0R A;  3G3C A;  1Y21 A;  5CFE A;  4B5G A;  3I5V A;  5INM A;  2A3Z B;  2J63 A;  4K6L F;  5J3Z A;  1E9N A;  4GEW A;  5J8N A;  5DFJ A;  1YJH A;  4F1H A;  3G2D A;  2JC4 A;  2V0S A;  2DDR A;  2A41 B;  1I9Y A;  3N9V A;  4B5J A;  3G6S A;  2F2F B;  2EI9 A;  1AKO A;  4L1Z A;  5DFF A;  3I48 A;  5INP A;  2VOA A;  5DV2 A;  4PUQ A;  3I41 A;  5DFI A;  2A40 B;  3W2Y A;  5INN A;  4QHE A;  1DE9 A;  3NGQ A;  3NGO A;  4FVA A;  3G4T A;  4C1R A;  4FPV A;  2DNJ A;  3L1W A;  5DG0 A;  2XSW A;  4JG3 A;  2O3C A;  3U8U A;  5J3S A;  5INQ A;  3K55 A;  1HD7 A;  2UYR X;  3I46 A;  3NR8 A;  4AWN A;  1SR4 B;  4GZ0 A;  5J3P A;  1DE8 A;  3NGN A;  5CFG A;  4QHD A;  2O3H A;  3CJC D;  5J42 A;  4LND A;  4B5I A;  1ZWX A;  4GZ1 A;  4F1R A;  1WDU A;  3W3D B;  4B5F A;  3WCX A;  1ATN D;  1NTF A;  2DDT A;  4F1I A;  4CML A;  5EWT A;  4F1H B;  1BIX A;  3G2C A;  4CMN A;  1DEW A;  2F1N A;  3G0R A;  5DV4 A;  3MPR A;  5INK A;  2IMQ X;  3G0A A;  3GA6 A;  2A42 B;  3G38 A;  4GYZ A;  3FZI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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