2O3CA

Crystal structure of zebrafish ape
Total Genus 93
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
93
sequence length
276
structure length
276
Chain Sequence
PILYEDPPEKLTSKDGRAANMKITSWNVDGLRAWVKKNGLDWVRKEDPDILCLQETKCAEKALPADITAMPEYPHKYWAGSEDKEGYSGVAMLCKTEPLNVTYGIGKEEHDKEGRVITAEFPDFFLVTAYVPNASRGLVRLDYRKTWDVDFRAYLCGLDARKPLVLCGDLNVAHQEIDLKNPKGNRKNAGFTPEEREGFTQLLEAGFTDSFRELYPDQAYAYTFWTYMMNARSKNVGWRLDYFVLSSALLPGLCDSKIRNTAMGSDHCPITLFLAV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease
pubmed doi rcsb
molecule tags Dna binding protein
source organism Danio rerio
molecule keywords APEX nuclease 1
total genus 93
structure length 276
sequence length 276
chains with identical sequence B, C
ec nomenclature ec 4.2.99.18: DNA-(apurinic or apyrimidinic site) lyase.
pdb deposition date 2006-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 2o3cA00
3W3DB 4B5FA 4GYZA 5INLA 5INKA 4F1IA 2O3HA 3W2YA 3G00A 5DFFA 3I46A 4L20A 1DE8A 3G2CA 1NTFA 3NR8A 1Y21A 5DG0A 2J63A 1ZWXA 4F1HA 4B5GA 2F2FB 4CMNA 3G8VA 4B5HA 5DFHA 4B5MA 2EI9A 1ATND 5INNA 4CMLA 5A7IA 4F1RA 1BIXA 2JC5A 2VOAA 4PUQA 5INQA 2IMQX 1DNKA 3DNIA 4QHDA 3I48A 4QH9A 2DDTA 1DE9A 3G6SA 2F1NA 2DDRA 4GEWA 3G2DA 4JG3A 5DV2A 1E9NA 4IEMA 2O3CA 4GZ0A 1DEWA 2DNJA 2ISIA 3K55A 1I9ZA 3G4TA 3MPRA 3N9VA 3MTCA 3G3CA 3NGQA 4K6LF 4FPVA 3G0AA 5CFGA 5INMA 2A42B 1SR4B 4B5IA 4F1HB 2V0SA 3U8UA 2JC4A 5J3ZA 3G1KA 3I5VA 5DFIA 1SI6X 5J3PA 1WDUA 2UYRX 5A7JA 3G3YA 2DDSA 1YJHA 5DV4A 5J8NA 4GZ2A 3G91A 5EWTA 5INPA 1I9YA 2D1KB 3I41A 1VYBA 5CFEA 2V0RA 5DFJA 3WCXA 4L1YA 4GZ1A 1AKOA 4B5JA 3TEBA 4A9CA 5J42A 4LNDA 3GA6A 3G38A 1HD7A 3NGOA 5J3SA 3G0RA 4L1ZA 5INOA 3NGNA 2XSWA 4C1RA 4L21A 2A40B 5HT2A 2A3ZB 4RUWA 3L1WA 4QHEA 3W2XA 3CJCD 2A41B 4FVAA 4AWNA 3FZIA
chains in the Genus database with same CATH superfamily
3W3DB 4B5FA 4GYZA 5INLA 5INKA 4F1IA 2O3HA 3W2YA 3G00A 5DFFA 3I46A 4L20A 1DE8A 3G2CA 1NTFA 3NR8A 1Y21A 5DG0A 2J63A 1ZWXA 4F1HA 4B5GA 2F2FB 4CMNA 3G8VA 4B5HA 5DFHA 4B5MA 2EI9A 1ATND 5INNA 4CMLA 5A7IA 4F1RA 1BIXA 2JC5A 2VOAA 4PUQA 5INQA 2IMQX 1DNKA 3DNIA 4QHDA 3I48A 4QH9A 2DDTA 1DE9A 3G6SA 2F1NA 2DDRA 4GEWA 3G2DA 4JG3A 5DV2A 1E9NA 4IEMA 2O3CA 4GZ0A 1DEWA 2DNJA 2ISIA 3K55A 1I9ZA 3G4TA 3MPRA 3N9VA 3MTCA 3G3CA 3NGQA 4K6LF 4FPVA 3G0AA 5CFGA 5INMA 2A42B 1SR4B 4B5IA 4F1HB 2V0SA 3U8UA 2JC4A 5J3ZA 3G1KA 3I5VA 5DFIA 1SI6X 5J3PA 1WDUA 2UYRX 5A7JA 3G3YA 2DDSA 1YJHA 5DV4A 5J8NA 4GZ2A 3G91A 5EWTA 5INPA 1I9YA 2D1KB 3I41A 1VYBA 5CFEA 2V0RA 5DFJA 3WCXA 4L1YA 4GZ1A 1AKOA 4B5JA 3TEBA 4A9CA 5J42A 4LNDA 3GA6A 3G38A 1HD7A 3NGOA 5J3SA 3G0RA 4L1ZA 5INOA 3NGNA 2XSWA 4C1RA 4L21A 2A40B 5HT2A 2A3ZB 4RUWA 3L1WA 4QHEA 3W2XA 3CJCD 2A41B 4FVAA 4AWNA 3FZIA
chains in the Genus database with same CATH topology
3W3DB 4B5FA 4GYZA 5INLA 5INKA 4F1IA 2O3HA 3W2YA 3G00A 5DFFA 3I46A 4L20A 1DE8A 3G2CA 1NTFA 3NR8A 1Y21A 5DG0A 2J63A 1ZWXA 4F1HA 4B5GA 2F2FB 4CMNA 3G8VA 4B5HA 5DFHA 4B5MA 2EI9A 1ATND 5INNA 4CMLA 5A7IA 4F1RA 1BIXA 2JC5A 2VOAA 4PUQA 5INQA 2IMQX 1DNKA 3DNIA 4QHDA 3I48A 4QH9A 2DDTA 1DE9A 3G6SA 2F1NA 2DDRA 4GEWA 3G2DA 4JG3A 5DV2A 1E9NA 4IEMA 2O3CA 4GZ0A 1DEWA 2DNJA 2ISIA 3K55A 1I9ZA 3G4TA 3MPRA 3N9VA 3MTCA 3G3CA 3NGQA 4K6LF 4FPVA 3G0AA 5CFGA 5INMA 2A42B 1SR4B 4B5IA 4F1HB 2V0SA 3U8UA 2JC4A 5J3ZA 3G1KA 3I5VA 5DFIA 1SI6X 5J3PA 1WDUA 2UYRX 5A7JA 3G3YA 2DDSA 1YJHA 5DV4A 5J8NA 4GZ2A 3G91A 5EWTA 5INPA 1I9YA 2D1KB 3I41A 1VYBA 5CFEA 2V0RA 5DFJA 3WCXA 4L1YA 4GZ1A 1AKOA 4B5JA 3TEBA 4A9CA 5J42A 4LNDA 3GA6A 3G38A 1HD7A 3NGOA 5J3SA 3G0RA 4L1ZA 5INOA 3NGNA 2XSWA 4C1RA 4L21A 2A40B 5HT2A 2A3ZB 4RUWA 3L1WA 4QHEA 3W2XA 3CJCD 2A41B 4FVAA 4AWNA 3FZIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3W3D B;  4B5F A;  4GYZ A;  5INL A;  5INK A;  4F1I A;  2O3H A;  3W2Y A;  3G00 A;  5DFF A;  3I46 A;  4L20 A;  1DE8 A;  3G2C A;  1NTF A;  3NR8 A;  1Y21 A;  5DG0 A;  2J63 A;  1ZWX A;  4F1H A;  4B5G A;  2F2F B;  4CMN A;  3G8V A;  4B5H A;  5DFH A;  4B5M A;  2EI9 A;  1ATN D;  5INN A;  4CML A;  5A7I A;  4F1R A;  1BIX A;  2JC5 A;  2VOA A;  4PUQ A;  5INQ A;  2IMQ X;  1DNK A;  3DNI A;  4QHD A;  3I48 A;  4QH9 A;  2DDT A;  1DE9 A;  3G6S A;  2F1N A;  2DDR A;  4GEW A;  3G2D A;  4JG3 A;  5DV2 A;  1E9N A;  4IEM A;  2O3C A;  4GZ0 A;  1DEW A;  2DNJ A;  2ISI A;  3K55 A;  1I9Z A;  3G4T A;  3MPR A;  3N9V A;  3MTC A;  3G3C A;  3NGQ A;  4K6L F;  4FPV A;  3G0A A;  5CFG A;  5INM A;  2A42 B;  1SR4 B;  4B5I A;  4F1H B;  2V0S A;  3U8U A;  2JC4 A;  5J3Z A;  3G1K A;  3I5V A;  5DFI A;  1SI6 X;  5J3P A;  1WDU A;  2UYR X;  5A7J A;  3G3Y A;  2DDS A;  1YJH A;  5DV4 A;  5J8N A;  4GZ2 A;  3G91 A;  5EWT A;  5INP A;  1I9Y A;  2D1K B;  3I41 A;  1VYB A;  5CFE A;  2V0R A;  5DFJ A;  3WCX A;  4L1Y A;  4GZ1 A;  1AKO A;  4B5J A;  3TEB A;  4A9C A;  5J42 A;  4LND A;  3GA6 A;  3G38 A;  1HD7 A;  3NGO A;  5J3S A;  3G0R A;  4L1Z A;  5INO A;  3NGN A;  2XSW A;  4C1R A;  4L21 A;  2A40 B;  5HT2 A;  2A3Z B;  4RUW A;  3L1W A;  4QHE A;  3W2X A;  3CJC D;  2A41 B;  4FVA A;  4AWN A;  3FZI A; 
#chains in the Genus database with same CATH topology
 3W3D B;  4B5F A;  4GYZ A;  5INL A;  5INK A;  4F1I A;  2O3H A;  3W2Y A;  3G00 A;  5DFF A;  3I46 A;  4L20 A;  1DE8 A;  3G2C A;  1NTF A;  3NR8 A;  1Y21 A;  5DG0 A;  2J63 A;  1ZWX A;  4F1H A;  4B5G A;  2F2F B;  4CMN A;  3G8V A;  4B5H A;  5DFH A;  4B5M A;  2EI9 A;  1ATN D;  5INN A;  4CML A;  5A7I A;  4F1R A;  1BIX A;  2JC5 A;  2VOA A;  4PUQ A;  5INQ A;  2IMQ X;  1DNK A;  3DNI A;  4QHD A;  3I48 A;  4QH9 A;  2DDT A;  1DE9 A;  3G6S A;  2F1N A;  2DDR A;  4GEW A;  3G2D A;  4JG3 A;  5DV2 A;  1E9N A;  4IEM A;  2O3C A;  4GZ0 A;  1DEW A;  2DNJ A;  2ISI A;  3K55 A;  1I9Z A;  3G4T A;  3MPR A;  3N9V A;  3MTC A;  3G3C A;  3NGQ A;  4K6L F;  4FPV A;  3G0A A;  5CFG A;  5INM A;  2A42 B;  1SR4 B;  4B5I A;  4F1H B;  2V0S A;  3U8U A;  2JC4 A;  5J3Z A;  3G1K A;  3I5V A;  5DFI A;  1SI6 X;  5J3P A;  1WDU A;  2UYR X;  5A7J A;  3G3Y A;  2DDS A;  1YJH A;  5DV4 A;  5J8N A;  4GZ2 A;  3G91 A;  5EWT A;  5INP A;  1I9Y A;  2D1K B;  3I41 A;  1VYB A;  5CFE A;  2V0R A;  5DFJ A;  3WCX A;  4L1Y A;  4GZ1 A;  1AKO A;  4B5J A;  3TEB A;  4A9C A;  5J42 A;  4LND A;  3GA6 A;  3G38 A;  1HD7 A;  3NGO A;  5J3S A;  3G0R A;  4L1Z A;  5INO A;  3NGN A;  2XSW A;  4C1R A;  4L21 A;  2A40 B;  5HT2 A;  2A3Z B;  4RUW A;  3L1W A;  4QHE A;  3W2X A;  3CJC D;  2A41 B;  4FVA A;  4AWN A;  3FZI A; 
#chains in the Genus database with same CATH homology
 3W3D B;  4B5F A;  4GYZ A;  5INL A;  5INK A;  4F1I A;  2O3H A;  3W2Y A;  3G00 A;  5DFF A;  3I46 A;  4L20 A;  1DE8 A;  3G2C A;  1NTF A;  3NR8 A;  1Y21 A;  5DG0 A;  2J63 A;  1ZWX A;  4F1H A;  4B5G A;  2F2F B;  4CMN A;  3G8V A;  4B5H A;  5DFH A;  4B5M A;  2EI9 A;  1ATN D;  5INN A;  4CML A;  5A7I A;  4F1R A;  1BIX A;  2JC5 A;  2VOA A;  4PUQ A;  5INQ A;  2IMQ X;  1DNK A;  3DNI A;  4QHD A;  3I48 A;  4QH9 A;  2DDT A;  1DE9 A;  3G6S A;  2F1N A;  2DDR A;  4GEW A;  3G2D A;  4JG3 A;  5DV2 A;  1E9N A;  4IEM A;  2O3C A;  4GZ0 A;  1DEW A;  2DNJ A;  2ISI A;  3K55 A;  1I9Z A;  3G4T A;  3MPR A;  3N9V A;  3MTC A;  3G3C A;  3NGQ A;  4K6L F;  4FPV A;  3G0A A;  5CFG A;  5INM A;  2A42 B;  1SR4 B;  4B5I A;  4F1H B;  2V0S A;  3U8U A;  2JC4 A;  5J3Z A;  3G1K A;  3I5V A;  5DFI A;  1SI6 X;  5J3P A;  1WDU A;  2UYR X;  5A7J A;  3G3Y A;  2DDS A;  1YJH A;  5DV4 A;  5J8N A;  4GZ2 A;  3G91 A;  5EWT A;  5INP A;  1I9Y A;  2D1K B;  3I41 A;  1VYB A;  5CFE A;  2V0R A;  5DFJ A;  3WCX A;  4L1Y A;  4GZ1 A;  1AKO A;  4B5J A;  3TEB A;  4A9C A;  5J42 A;  4LND A;  3GA6 A;  3G38 A;  1HD7 A;  3NGO A;  5J3S A;  3G0R A;  4L1Z A;  5INO A;  3NGN A;  2XSW A;  4C1R A;  4L21 A;  2A40 B;  5HT2 A;  2A3Z B;  4RUW A;  3L1W A;  4QHE A;  3W2X A;  3CJC D;  2A41 B;  4FVA A;  4AWN A;  3FZI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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