3CJCD

Actin dimer cross-linked by v. cholerae martx toxin and complexed with dnase i and gelsolin-segment 1
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
260
structure length
258
Chain Sequence
LKIAAFNIRTFGETKMSNATLASYIVRIVRRYDIVLIQEVRDSHLVAVGKLLDYLNQDDPNTYHYVVSEPLGRNSYKERYLFLFRPNKVSVLDTYQYDDGCCGNDSFSREPAVVKFSSHSTKVKEFAIVALHSAPSDAVAEINSLYDVYLDVQQKWHLNDVMLMGDFNADCSYVTSSQWSSIRLRTSSTFQWLIPDSADTTATSTNCAYDRIVVAGSLLQSSVVPGSAAPFDFQAAYGLSNEMALAISDHYPVEVTLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Connecting actin monomers by iso-peptide bond is a toxicity mechanism of the Vibrio cholerae MARTX toxin.
pubmed doi rcsb
molecule tags Structural protein/hydrolase
source organism Homo sapiens
molecule keywords Actin, alpha skeletal muscle
total genus 75
structure length 258
sequence length 260
ec nomenclature ec 3.1.21.1: Deoxyribonuclease I.
pdb deposition date 2008-03-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 3cjcD00
3G4TA 4GYZA 5J42A 3NGQA 4GZ0A 4F1IA 4JG3A 2A3ZB 1NTFA 4FPVA 1SR4B 3G2DA 2EI9A 4CMNA 2F1NA 3G8VA 4LNDA 5DFJA 3U8UA 3NGNA 4B5JA 2ISIA 5J3PA 3G6SA 4B5GA 4B5MA 5DV4A 1DEWA 1SI6X 4GEWA 2F2FB 5DFHA 5CFEA 3NGOA 2D1KB 3DNIA 3N9VA 3G00A 2DNJA 3MPRA 3G3YA 2J63A 1VYBA 4QHDA 1WDUA 3FZIA 3NR8A 3L1WA 4GZ2A 2DDRA 4B5HA 3W2XA 4L1YA 4L20A 1DE8A 5DG0A 4QH9A 3I5VA 1DE9A 5EWTA 3G3CA 2A40B 3G0RA 1I9ZA 4A9CA 2O3HA 2O3CA 4QHEA 3I48A 2V0SA 1AKOA 5J3ZA 5A7IA 4RUWA 4B5FA 4GZ1A 3W3DB 5J8NA 4F1RA 2UYRX 5HT2A 3MTCA 1DNKA 4AWNA 5INNA 3G38A 4L21A 5INKA 4F1HB 1YJHA 3I46A 5J3SA 3K55A 5DFFA 4FVAA 5INQA 1ZWXA 2VOAA 3G2CA 1E9NA 2IMQX 1I9YA 2V0RA 3TEBA 4CMLA 2JC4A 4B5IA 3G1KA 4L1ZA 3WCXA 1Y21A 5INOA 4K6LF 2JC5A 5CFGA 4PUQA 1ATND 5INPA 3G91A 4IEMA 3W2YA 2XSWA 5INMA 3G0AA 4F1HA 2A42B 3GA6A 3CJCD 5DV2A 5DFIA 4C1RA 5INLA 2A41B 5A7JA 2DDSA 1BIXA 2DDTA 3I41A 1HD7A
chains in the Genus database with same CATH superfamily
3G4TA 4GYZA 5J42A 3NGQA 4GZ0A 4F1IA 4JG3A 2A3ZB 1NTFA 4FPVA 1SR4B 3G2DA 2EI9A 4CMNA 2F1NA 3G8VA 4LNDA 5DFJA 3U8UA 3NGNA 4B5JA 2ISIA 5J3PA 3G6SA 4B5GA 4B5MA 5DV4A 1DEWA 1SI6X 4GEWA 2F2FB 5DFHA 5CFEA 3NGOA 2D1KB 3DNIA 3N9VA 3G00A 2DNJA 3MPRA 3G3YA 2J63A 1VYBA 4QHDA 1WDUA 3FZIA 3NR8A 3L1WA 4GZ2A 2DDRA 4B5HA 3W2XA 4L1YA 4L20A 1DE8A 5DG0A 4QH9A 3I5VA 1DE9A 5EWTA 3G3CA 2A40B 3G0RA 1I9ZA 4A9CA 2O3HA 2O3CA 4QHEA 3I48A 2V0SA 1AKOA 5J3ZA 5A7IA 4RUWA 4B5FA 4GZ1A 3W3DB 5J8NA 4F1RA 2UYRX 5HT2A 3MTCA 1DNKA 4AWNA 5INNA 3G38A 4L21A 5INKA 4F1HB 1YJHA 3I46A 5J3SA 3K55A 5DFFA 4FVAA 5INQA 1ZWXA 2VOAA 3G2CA 1E9NA 2IMQX 1I9YA 2V0RA 3TEBA 4CMLA 2JC4A 4B5IA 3G1KA 4L1ZA 3WCXA 1Y21A 5INOA 4K6LF 2JC5A 5CFGA 4PUQA 1ATND 5INPA 3G91A 4IEMA 3W2YA 2XSWA 5INMA 3G0AA 4F1HA 2A42B 3GA6A 3CJCD 5DV2A 5DFIA 4C1RA 5INLA 2A41B 5A7JA 2DDSA 1BIXA 2DDTA 3I41A 1HD7A
chains in the Genus database with same CATH topology
3G4TA 4GYZA 5J42A 3NGQA 4GZ0A 4F1IA 4JG3A 2A3ZB 1NTFA 4FPVA 1SR4B 3G2DA 2EI9A 4CMNA 2F1NA 3G8VA 4LNDA 5DFJA 3U8UA 3NGNA 4B5JA 2ISIA 5J3PA 3G6SA 4B5GA 4B5MA 5DV4A 1DEWA 1SI6X 4GEWA 2F2FB 5DFHA 5CFEA 3NGOA 2D1KB 3DNIA 3N9VA 3G00A 2DNJA 3MPRA 3G3YA 2J63A 1VYBA 4QHDA 1WDUA 3FZIA 3NR8A 3L1WA 4GZ2A 2DDRA 4B5HA 3W2XA 4L1YA 4L20A 1DE8A 5DG0A 4QH9A 3I5VA 1DE9A 5EWTA 3G3CA 2A40B 3G0RA 1I9ZA 4A9CA 2O3HA 2O3CA 4QHEA 3I48A 2V0SA 1AKOA 5J3ZA 5A7IA 4RUWA 4B5FA 4GZ1A 3W3DB 5J8NA 4F1RA 2UYRX 5HT2A 3MTCA 1DNKA 4AWNA 5INNA 3G38A 4L21A 5INKA 4F1HB 1YJHA 3I46A 5J3SA 3K55A 5DFFA 4FVAA 5INQA 1ZWXA 2VOAA 3G2CA 1E9NA 2IMQX 1I9YA 2V0RA 3TEBA 4CMLA 2JC4A 4B5IA 3G1KA 4L1ZA 3WCXA 1Y21A 5INOA 4K6LF 2JC5A 5CFGA 4PUQA 1ATND 5INPA 3G91A 4IEMA 3W2YA 2XSWA 5INMA 3G0AA 4F1HA 2A42B 3GA6A 3CJCD 5DV2A 5DFIA 4C1RA 5INLA 2A41B 5A7JA 2DDSA 1BIXA 2DDTA 3I41A 1HD7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3G4T A;  4GYZ A;  5J42 A;  3NGQ A;  4GZ0 A;  4F1I A;  4JG3 A;  2A3Z B;  1NTF A;  4FPV A;  1SR4 B;  3G2D A;  2EI9 A;  4CMN A;  2F1N A;  3G8V A;  4LND A;  5DFJ A;  3U8U A;  3NGN A;  4B5J A;  2ISI A;  5J3P A;  3G6S A;  4B5G A;  4B5M A;  5DV4 A;  1DEW A;  1SI6 X;  4GEW A;  2F2F B;  5DFH A;  5CFE A;  3NGO A;  2D1K B;  3DNI A;  3N9V A;  3G00 A;  2DNJ A;  3MPR A;  3G3Y A;  2J63 A;  1VYB A;  4QHD A;  1WDU A;  3FZI A;  3NR8 A;  3L1W A;  4GZ2 A;  2DDR A;  4B5H A;  3W2X A;  4L1Y A;  4L20 A;  1DE8 A;  5DG0 A;  4QH9 A;  3I5V A;  1DE9 A;  5EWT A;  3G3C A;  2A40 B;  3G0R A;  1I9Z A;  4A9C A;  2O3H A;  2O3C A;  4QHE A;  3I48 A;  2V0S A;  1AKO A;  5J3Z A;  5A7I A;  4RUW A;  4B5F A;  4GZ1 A;  3W3D B;  5J8N A;  4F1R A;  2UYR X;  5HT2 A;  3MTC A;  1DNK A;  4AWN A;  5INN A;  3G38 A;  4L21 A;  5INK A;  4F1H B;  1YJH A;  3I46 A;  5J3S A;  3K55 A;  5DFF A;  4FVA A;  5INQ A;  1ZWX A;  2VOA A;  3G2C A;  1E9N A;  2IMQ X;  1I9Y A;  2V0R A;  3TEB A;  4CML A;  2JC4 A;  4B5I A;  3G1K A;  4L1Z A;  3WCX A;  1Y21 A;  5INO A;  4K6L F;  2JC5 A;  5CFG A;  4PUQ A;  1ATN D;  5INP A;  3G91 A;  4IEM A;  3W2Y A;  2XSW A;  5INM A;  3G0A A;  4F1H A;  2A42 B;  3GA6 A;  3CJC D;  5DV2 A;  5DFI A;  4C1R A;  5INL A;  2A41 B;  5A7J A;  2DDS A;  1BIX A;  2DDT A;  3I41 A;  1HD7 A; 
#chains in the Genus database with same CATH topology
 3G4T A;  4GYZ A;  5J42 A;  3NGQ A;  4GZ0 A;  4F1I A;  4JG3 A;  2A3Z B;  1NTF A;  4FPV A;  1SR4 B;  3G2D A;  2EI9 A;  4CMN A;  2F1N A;  3G8V A;  4LND A;  5DFJ A;  3U8U A;  3NGN A;  4B5J A;  2ISI A;  5J3P A;  3G6S A;  4B5G A;  4B5M A;  5DV4 A;  1DEW A;  1SI6 X;  4GEW A;  2F2F B;  5DFH A;  5CFE A;  3NGO A;  2D1K B;  3DNI A;  3N9V A;  3G00 A;  2DNJ A;  3MPR A;  3G3Y A;  2J63 A;  1VYB A;  4QHD A;  1WDU A;  3FZI A;  3NR8 A;  3L1W A;  4GZ2 A;  2DDR A;  4B5H A;  3W2X A;  4L1Y A;  4L20 A;  1DE8 A;  5DG0 A;  4QH9 A;  3I5V A;  1DE9 A;  5EWT A;  3G3C A;  2A40 B;  3G0R A;  1I9Z A;  4A9C A;  2O3H A;  2O3C A;  4QHE A;  3I48 A;  2V0S A;  1AKO A;  5J3Z A;  5A7I A;  4RUW A;  4B5F A;  4GZ1 A;  3W3D B;  5J8N A;  4F1R A;  2UYR X;  5HT2 A;  3MTC A;  1DNK A;  4AWN A;  5INN A;  3G38 A;  4L21 A;  5INK A;  4F1H B;  1YJH A;  3I46 A;  5J3S A;  3K55 A;  5DFF A;  4FVA A;  5INQ A;  1ZWX A;  2VOA A;  3G2C A;  1E9N A;  2IMQ X;  1I9Y A;  2V0R A;  3TEB A;  4CML A;  2JC4 A;  4B5I A;  3G1K A;  4L1Z A;  3WCX A;  1Y21 A;  5INO A;  4K6L F;  2JC5 A;  5CFG A;  4PUQ A;  1ATN D;  5INP A;  3G91 A;  4IEM A;  3W2Y A;  2XSW A;  5INM A;  3G0A A;  4F1H A;  2A42 B;  3GA6 A;  3CJC D;  5DV2 A;  5DFI A;  4C1R A;  5INL A;  2A41 B;  5A7J A;  2DDS A;  1BIX A;  2DDT A;  3I41 A;  1HD7 A; 
#chains in the Genus database with same CATH homology
 3G4T A;  4GYZ A;  5J42 A;  3NGQ A;  4GZ0 A;  4F1I A;  4JG3 A;  2A3Z B;  1NTF A;  4FPV A;  1SR4 B;  3G2D A;  2EI9 A;  4CMN A;  2F1N A;  3G8V A;  4LND A;  5DFJ A;  3U8U A;  3NGN A;  4B5J A;  2ISI A;  5J3P A;  3G6S A;  4B5G A;  4B5M A;  5DV4 A;  1DEW A;  1SI6 X;  4GEW A;  2F2F B;  5DFH A;  5CFE A;  3NGO A;  2D1K B;  3DNI A;  3N9V A;  3G00 A;  2DNJ A;  3MPR A;  3G3Y A;  2J63 A;  1VYB A;  4QHD A;  1WDU A;  3FZI A;  3NR8 A;  3L1W A;  4GZ2 A;  2DDR A;  4B5H A;  3W2X A;  4L1Y A;  4L20 A;  1DE8 A;  5DG0 A;  4QH9 A;  3I5V A;  1DE9 A;  5EWT A;  3G3C A;  2A40 B;  3G0R A;  1I9Z A;  4A9C A;  2O3H A;  2O3C A;  4QHE A;  3I48 A;  2V0S A;  1AKO A;  5J3Z A;  5A7I A;  4RUW A;  4B5F A;  4GZ1 A;  3W3D B;  5J8N A;  4F1R A;  2UYR X;  5HT2 A;  3MTC A;  1DNK A;  4AWN A;  5INN A;  3G38 A;  4L21 A;  5INK A;  4F1H B;  1YJH A;  3I46 A;  5J3S A;  3K55 A;  5DFF A;  4FVA A;  5INQ A;  1ZWX A;  2VOA A;  3G2C A;  1E9N A;  2IMQ X;  1I9Y A;  2V0R A;  3TEB A;  4CML A;  2JC4 A;  4B5I A;  3G1K A;  4L1Z A;  3WCX A;  1Y21 A;  5INO A;  4K6L F;  2JC5 A;  5CFG A;  4PUQ A;  1ATN D;  5INP A;  3G91 A;  4IEM A;  3W2Y A;  2XSW A;  5INM A;  3G0A A;  4F1H A;  2A42 B;  3GA6 A;  3CJC D;  5DV2 A;  5DFI A;  4C1R A;  5INL A;  2A41 B;  5A7J A;  2DDS A;  1BIX A;  2DDT A;  3I41 A;  1HD7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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