3DEBA

Crystal structure of apo form (zinc removed) of the botulinum neurotoxin type c light chain
Total Genus 143
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
143
sequence length
432
structure length
432
Chain Sequence
SHMPITINNFNYSDPVDNKNILYLDTHLNTLANEPEKAFRITGNIWVIPDRFSRNSNPNLNKPPRVTSPKSGYYDPNYLSTDSDKDTFLKEIIKLFKRINSREIGEELIYRLSTDIPFPGNNNTPINTFDFDVDFNSVDVKTRQGNNWVKTGSINPSVIITGPRENIIDPETSTFKLTNNTFAAQEGFGALSIISISPRFMLTYSNATNDVGEGRFSKSEFCMDPILILMHELNHAMHNLYGIAIPNDQTISSVTSNIFYSQYNVKLEYAEIYAFGGPTIDLIPKSARKYFEEKALDYYRSIAKRLNSITTANPSSFNKYIGEYKQKLIRKYRFVVESSGEVTVNRNKFVELYNELTQIFTEFNYAKIYNVQNRKIYLSNVYTPVTANILDDNVYDIQNGFNIPKSNLNVLFMGQNLSRNPALRKVNPENML
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of apo form (Zinc removed) of the Botulinum Neurotoxin Type C Light Chain
rcsb
molecule tags Hydrolase
source organism Clostridium botulinum
molecule keywords Botulinum neurotoxin C1 light chain
total genus 143
structure length 432
sequence length 432
ec nomenclature ec 3.4.24.69: Bontoxilysin.
pdb deposition date 2008-06-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01742 Peptidase_M27 Clostridial neurotoxin zinc protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1240.10 Alpha Beta Alpha-Beta Complex Zincin-like Metalloproteases ("zincins"), catalytic domain like 3debA00
1ZN3A 3FIEA 2ETFA 3DS9A 3BOKA 4J1LA 3DDBA 4ZJXA 1YVGA 3V0AB 2W2DA 3ZUSA 2A8AA 3C89A 4KTXA 2ILPA 3QIYA 2QN0A 2ISGA 2IMAA 1ZKXA 1S0GA 3DDAA 1G9CA 3QW5A 4ZKTB 3NF3A 3QW6A 3QJ0A 1I1EA 1EPWA 4ELCA 3V0BA 4KUFA 2IMBA 3QIXA 3BTAA 3QIZA 2A97A 3BWIA 3C88A 2ISEA 1S0CA 3DSEA 1ZL6A 1Z7HA 2ISHA 2G7QA 2G7NA 3V0AA 3BONA 2NYYA 2XHLA 2G7KA 1S0EA 5BQMA 1T3CA 4KS6A 3D3XA 3ZURA 2NP0A 4EJ5A 1G9AA 2IMCA 1ZL5A 5BQNA 4HEVA 2G7PA 3C8BA 1F82A 3C8AA 1F31A 3K3QB 3FFZA 3QW7A 3DEBA 3VUOA 3ZUQA 3FIIA 1S0DA 1E1HA 1G9DA 1T3AA 2NZ9A 3QW8A 1S0BA 3BOOA 1XTFA 3V0BB 1ZKWA 1S0FA 1ZB7A 1G9BA 2FPQA 4EL4A 1XTGA
chains in the Genus database with same CATH superfamily
1ZN3A 3FIEA 2ETFA 3DS9A 3BOKA 4J1LA 3DDBA 4ZJXA 1YVGA 3V0AB 2YPTA 2W2DA 3ZUSA 4AW6A 2A8AA 3C89A 4KTXA 2ILPA 3QIYA 2QN0A 2ISGA 4JIXA 2IMAA 1ZKXA 1S0GA 3DDAA 1G9CA 3QW5A 4ZKTB 3NF3A 3QW6A 3QJ0A 1I1EA 1EPWA 4ELCA 3V0BA 4KUFA 2IMBA 3QIXA 4IL3A 3BTAA 3QIZA 2A97A 3BWIA 3C88A 2ISEA 4QHFA 1S0CA 3DSEA 1ZL6A 1Z7HA 2ISHA 2G7QA 2G7NA 3V0AA 3BONA 2NYYA 2XHLA 2G7KA 2EJQA 1S0EA 5BQMA 1T3CA 4KS6A 3D3XA 3ZURA 2NP0A 4EJ5A 1G9AA 4JIUA 2IMCA 1ZL5A 5BQNA 4HEVA 3E11A 2G7PA 3C8BA 1F82A 3C8AA 1F31A 3K3QB 3FFZA 3QW7A 3DEBA 3VUOA 3ZUQA 3FIIA 1S0DA 1E1HA 1G9DA 1T3AA 2NZ9A 3QW8A 1S0BA 3BOOA 1XTFA 3V0BB 1ZKWA 1S0FA 1ZB7A 1G9BA 3CQBA 2FPQA 4EL4A 1XTGA
chains in the Genus database with same CATH topology
1ZN3A 3FIEA 2ETFA 3DS9A 3BOKA 4J1LA 3DDBA 4ZJXA 1YVGA 3V0AB 2W2DA 3ZUSA 2A8AA 3C89A 4KTXA 2ILPA 3QIYA 2QN0A 2ISGA 2IMAA 1ZKXA 1S0GA 3DDAA 1G9CA 3QW5A 4ZKTB 3NF3A 3QW6A 3QJ0A 1I1EA 1EPWA 4ELCA 3V0BA 4KUFA 2IMBA 3QIXA 3BTAA 3QIZA 2A97A 3BWIA 3C88A 2ISEA 1S0CA 3DSEA 1ZL6A 1Z7HA 2ISHA 2G7QA 2G7NA 3V0AA 3BONA 2NYYA 2XHLA 2G7KA 1S0EA 5BQMA 1T3CA 4KS6A 3D3XA 3ZURA 2NP0A 4EJ5A 1G9AA 2IMCA 1ZL5A 5BQNA 4HEVA 2G7PA 3C8BA 1F82A 3C8AA 1F31A 3K3QB 3FFZA 3QW7A 3DEBA 3VUOA 3ZUQA 3FIIA 1S0DA 1E1HA 1G9DA 1T3AA 2NZ9A 3QW8A 1S0BA 3BOOA 1XTFA 3V0BB 1ZKWA 1S0FA 1ZB7A 1G9BA 2FPQA 4EL4A 1XTGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZN3 A;  3FIE A;  2ETF A;  3DS9 A;  3BOK A;  4J1L A;  3DDB A;  4ZJX A;  1YVG A;  3V0A B;  2W2D A;  3ZUS A;  2A8A A;  3C89 A;  4KTX A;  2ILP A;  3QIY A;  2QN0 A;  2ISG A;  2IMA A;  1ZKX A;  1S0G A;  3DDA A;  1G9C A;  3QW5 A;  4ZKT B;  3NF3 A;  3QW6 A;  3QJ0 A;  1I1E A;  1EPW A;  4ELC A;  3V0B A;  4KUF A;  2IMB A;  3QIX A;  3BTA A;  3QIZ A;  2A97 A;  3BWI A;  3C88 A;  2ISE A;  1S0C A;  3DSE A;  1ZL6 A;  1Z7H A;  2ISH A;  2G7Q A;  2G7N A;  3V0A A;  3BON A;  2NYY A;  2XHL A;  2G7K A;  1S0E A;  5BQM A;  1T3C A;  4KS6 A;  3D3X A;  3ZUR A;  2NP0 A;  4EJ5 A;  1G9A A;  2IMC A;  1ZL5 A;  5BQN A;  4HEV A;  2G7P A;  3C8B A;  1F82 A;  3C8A A;  1F31 A;  3K3Q B;  3FFZ A;  3QW7 A;  3DEB A;  3VUO A;  3ZUQ A;  3FII A;  1S0D A;  1E1H A;  1G9D A;  1T3A A;  2NZ9 A;  3QW8 A;  1S0B A;  3BOO A;  1XTF A;  3V0B B;  1ZKW A;  1S0F A;  1ZB7 A;  1G9B A;  2FPQ A;  4EL4 A;  1XTG A; 
#chains in the Genus database with same CATH topology
 1ZN3 A;  3FIE A;  2ETF A;  3DS9 A;  3BOK A;  4J1L A;  3DDB A;  4ZJX A;  1YVG A;  3V0A B;  2YPT A;  2W2D A;  3ZUS A;  4AW6 A;  2A8A A;  3C89 A;  4KTX A;  2ILP A;  3QIY A;  2QN0 A;  2ISG A;  4JIX A;  2IMA A;  1ZKX A;  1S0G A;  3DDA A;  1G9C A;  3QW5 A;  4ZKT B;  3NF3 A;  3QW6 A;  3QJ0 A;  1I1E A;  1EPW A;  4ELC A;  3V0B A;  4KUF A;  2IMB A;  3QIX A;  4IL3 A;  3BTA A;  3QIZ A;  2A97 A;  3BWI A;  3C88 A;  2ISE A;  4QHF A;  1S0C A;  3DSE A;  1ZL6 A;  1Z7H A;  2ISH A;  2G7Q A;  2G7N A;  3V0A A;  3BON A;  2NYY A;  2XHL A;  2G7K A;  2EJQ A;  1S0E A;  5BQM A;  1T3C A;  4KS6 A;  3D3X A;  3ZUR A;  2NP0 A;  4EJ5 A;  1G9A A;  4JIU A;  2IMC A;  1ZL5 A;  5BQN A;  4HEV A;  3E11 A;  2G7P A;  3C8B A;  1F82 A;  3C8A A;  1F31 A;  3K3Q B;  3FFZ A;  3QW7 A;  3DEB A;  3VUO A;  3ZUQ A;  3FII A;  1S0D A;  1E1H A;  1G9D A;  1T3A A;  2NZ9 A;  3QW8 A;  1S0B A;  3BOO A;  1XTF A;  3V0B B;  1ZKW A;  1S0F A;  1ZB7 A;  1G9B A;  3CQB A;  2FPQ A;  4EL4 A;  1XTG A; 
#chains in the Genus database with same CATH homology
 1ZN3 A;  3FIE A;  2ETF A;  3DS9 A;  3BOK A;  4J1L A;  3DDB A;  4ZJX A;  1YVG A;  3V0A B;  2W2D A;  3ZUS A;  2A8A A;  3C89 A;  4KTX A;  2ILP A;  3QIY A;  2QN0 A;  2ISG A;  2IMA A;  1ZKX A;  1S0G A;  3DDA A;  1G9C A;  3QW5 A;  4ZKT B;  3NF3 A;  3QW6 A;  3QJ0 A;  1I1E A;  1EPW A;  4ELC A;  3V0B A;  4KUF A;  2IMB A;  3QIX A;  3BTA A;  3QIZ A;  2A97 A;  3BWI A;  3C88 A;  2ISE A;  1S0C A;  3DSE A;  1ZL6 A;  1Z7H A;  2ISH A;  2G7Q A;  2G7N A;  3V0A A;  3BON A;  2NYY A;  2XHL A;  2G7K A;  1S0E A;  5BQM A;  1T3C A;  4KS6 A;  3D3X A;  3ZUR A;  2NP0 A;  4EJ5 A;  1G9A A;  2IMC A;  1ZL5 A;  5BQN A;  4HEV A;  2G7P A;  3C8B A;  1F82 A;  3C8A A;  1F31 A;  3K3Q B;  3FFZ A;  3QW7 A;  3DEB A;  3VUO A;  3ZUQ A;  3FII A;  1S0D A;  1E1H A;  1G9D A;  1T3A A;  2NZ9 A;  3QW8 A;  1S0B A;  3BOO A;  1XTF A;  3V0B B;  1ZKW A;  1S0F A;  1ZB7 A;  1G9B A;  2FPQ A;  4EL4 A;  1XTG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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