3FIIA

Crystal structure of clostridium botulinum neurotoxin serotype f catalytic domain with an inhibitor (inh2)
Total Genus 136
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
136
sequence length
411
structure length
403
Chain Sequence
PVVINSFNYNDPVNDDTILYMQIPYEEKSKKYYKAFEIMRNVWIIPERNTIGTDPSDFDPPASLENGSSAYYDPNYLTTDAEKDRYLKTTIKLFKRINSNPAGEVLLQEISYAKPYLGNEHTPINEFHPVTRTTSVNIKSSTNVKSSIILNLLVLGAGPDIFENSSYPVRKLMDSGGVYDPSNDGFGSINIVTFSPEYEYTFNDTESFIADPAISLAHELIHALHGLYGARGVTYKETIKVKQAPLMIAEKPIRLEEFLTFGGQDLNIITSAMKEKIYNNLLANYEKIATRLSRVNSAPPEYDINEYKDYFQWKYGLDKNADGSYTVNENKFNEIYKKLYSFTEIDLANKFKVKCRNTYFIKYGFLKVPNLLDDDIYTVSEGFNIGNLAVNNRGQNIKLNPKI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mode of VAMP substrate recognition and inhibition of Clostridium botulinum neurotoxin F.
pubmed doi rcsb
molecule tags Hydrolase, toxin/protein transport
source organism Clostridium botulinum
molecule keywords BOTULINUM NEUROTOXIN TYPE F
total genus 136
structure length 403
sequence length 411
ec nomenclature ec 3.4.24.69: Bontoxilysin.
pdb deposition date 2008-12-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01742 Peptidase_M27 Clostridial neurotoxin zinc protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1240.10 Alpha Beta Alpha-Beta Complex Zincin-like Metalloproteases ("zincins"), catalytic domain like 3fiiA00
3QW7A 1S0BA 3BONA 2ISEA 1ZN3A 2G7PA 2FPQA 2XHLA 2G7QA 2NYYA 4HEVA 1S0CA 3BOKA 3NF3A 2A97A 4ZKTB 3QW6A 1ZL5A 3DDBA 3DSEA 4EL4A 3V0AB 2W2DA 2ISGA 2ETFA 1EPWA 3V0BB 3ZUQA 1F31A 1Z7HA 3QIXA 3FIIA 4EJ5A 1YVGA 2ILPA 1S0DA 3V0AA 4J1LA 2QN0A 3C8BA 2G7KA 1G9DA 3V0BA 1E1HA 1I1EA 2G7NA 1S0EA 3ZURA 3C89A 1XTFA 2IMBA 2A8AA 2NP0A 4KUFA 1T3CA 1T3AA 1G9BA 1ZL6A 2IMAA 3BWIA 3VUOA 2ISHA 1G9CA 3DDAA 3BOOA 1S0FA 3C8AA 4KS6A 4ZJXA 3QIZA 3FIEA 4KTXA 3DEBA 3BTAA 1ZKXA 5BQNA 1XTGA 1ZB7A 1F82A 4ELCA 3K3QB 3QIYA 3D3XA 3ZUSA 3DS9A 3QW5A 2NZ9A 5BQMA 1ZKWA 1G9AA 3FFZA 1S0GA 3QW8A 2IMCA 3C88A 3QJ0A
chains in the Genus database with same CATH superfamily
3QW7A 1S0BA 3BONA 2ISEA 1ZN3A 2G7PA 2FPQA 2XHLA 2G7QA 3E11A 2NYYA 4HEVA 1S0CA 4JIUA 3BOKA 4AW6A 3NF3A 2A97A 4ZKTB 3QW6A 1ZL5A 3DDBA 3DSEA 4QHFA 4EL4A 3V0AB 2W2DA 2ISGA 2ETFA 1EPWA 3V0BB 3ZUQA 1F31A 1Z7HA 3QIXA 3FIIA 4EJ5A 1YVGA 2ILPA 1S0DA 2YPTA 3V0AA 4J1LA 2QN0A 3C8BA 2G7KA 1G9DA 3V0BA 1E1HA 1I1EA 2G7NA 1S0EA 3ZURA 3C89A 1XTFA 2IMBA 2A8AA 2NP0A 4KUFA 4IL3A 1T3CA 1T3AA 1G9BA 1ZL6A 2IMAA 3BWIA 3VUOA 2ISHA 1G9CA 3DDAA 3BOOA 1S0FA 3C8AA 4KS6A 4ZJXA 3QIZA 3FIEA 3DEBA 3BTAA 4KTXA 1ZKXA 4JIXA 5BQNA 1XTGA 1ZB7A 1F82A 4ELCA 3K3QB 3QIYA 3D3XA 3ZUSA 3DS9A 3QW5A 2NZ9A 3CQBA 2EJQA 5BQMA 1ZKWA 1G9AA 3FFZA 1S0GA 3QW8A 2IMCA 3C88A 3QJ0A
chains in the Genus database with same CATH topology
3QW7A 1S0BA 3BONA 2ISEA 1ZN3A 2G7PA 2FPQA 2XHLA 2G7QA 2NYYA 4HEVA 1S0CA 3BOKA 3NF3A 2A97A 4ZKTB 3QW6A 1ZL5A 3DDBA 3DSEA 4EL4A 3V0AB 2W2DA 2ISGA 2ETFA 1EPWA 3V0BB 3ZUQA 1F31A 1Z7HA 3QIXA 3FIIA 4EJ5A 1YVGA 2ILPA 1S0DA 3V0AA 4J1LA 2QN0A 3C8BA 2G7KA 1G9DA 3V0BA 1E1HA 1I1EA 2G7NA 1S0EA 3ZURA 3C89A 1XTFA 2IMBA 2A8AA 2NP0A 4KUFA 1T3CA 1T3AA 1G9BA 1ZL6A 2IMAA 3BWIA 3VUOA 2ISHA 1G9CA 3DDAA 3BOOA 1S0FA 3C8AA 4KS6A 4ZJXA 3QIZA 3FIEA 4KTXA 3DEBA 3BTAA 1ZKXA 5BQNA 1XTGA 1ZB7A 1F82A 4ELCA 3K3QB 3QIYA 3D3XA 3ZUSA 3DS9A 3QW5A 2NZ9A 5BQMA 1ZKWA 1G9AA 3FFZA 1S0GA 3QW8A 2IMCA 3C88A 3QJ0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QW7 A;  1S0B A;  3BON A;  2ISE A;  1ZN3 A;  2G7P A;  2FPQ A;  2XHL A;  2G7Q A;  2NYY A;  4HEV A;  1S0C A;  3BOK A;  3NF3 A;  2A97 A;  4ZKT B;  3QW6 A;  1ZL5 A;  3DDB A;  3DSE A;  4EL4 A;  3V0A B;  2W2D A;  2ISG A;  2ETF A;  1EPW A;  3V0B B;  3ZUQ A;  1F31 A;  1Z7H A;  3QIX A;  3FII A;  4EJ5 A;  1YVG A;  2ILP A;  1S0D A;  3V0A A;  4J1L A;  2QN0 A;  3C8B A;  2G7K A;  1G9D A;  3V0B A;  1E1H A;  1I1E A;  2G7N A;  1S0E A;  3ZUR A;  3C89 A;  1XTF A;  2IMB A;  2A8A A;  2NP0 A;  4KUF A;  1T3C A;  1T3A A;  1G9B A;  1ZL6 A;  2IMA A;  3BWI A;  3VUO A;  2ISH A;  1G9C A;  3DDA A;  3BOO A;  1S0F A;  3C8A A;  4KS6 A;  4ZJX A;  3QIZ A;  3FIE A;  4KTX A;  3DEB A;  3BTA A;  1ZKX A;  5BQN A;  1XTG A;  1ZB7 A;  1F82 A;  4ELC A;  3K3Q B;  3QIY A;  3D3X A;  3ZUS A;  3DS9 A;  3QW5 A;  2NZ9 A;  5BQM A;  1ZKW A;  1G9A A;  3FFZ A;  1S0G A;  3QW8 A;  2IMC A;  3C88 A;  3QJ0 A; 
#chains in the Genus database with same CATH topology
 3QW7 A;  1S0B A;  3BON A;  2ISE A;  1ZN3 A;  2G7P A;  2FPQ A;  2XHL A;  2G7Q A;  3E11 A;  2NYY A;  4HEV A;  1S0C A;  4JIU A;  3BOK A;  4AW6 A;  3NF3 A;  2A97 A;  4ZKT B;  3QW6 A;  1ZL5 A;  3DDB A;  3DSE A;  4QHF A;  4EL4 A;  3V0A B;  2W2D A;  2ISG A;  2ETF A;  1EPW A;  3V0B B;  3ZUQ A;  1F31 A;  1Z7H A;  3QIX A;  3FII A;  4EJ5 A;  1YVG A;  2ILP A;  1S0D A;  2YPT A;  3V0A A;  4J1L A;  2QN0 A;  3C8B A;  2G7K A;  1G9D A;  3V0B A;  1E1H A;  1I1E A;  2G7N A;  1S0E A;  3ZUR A;  3C89 A;  1XTF A;  2IMB A;  2A8A A;  2NP0 A;  4KUF A;  4IL3 A;  1T3C A;  1T3A A;  1G9B A;  1ZL6 A;  2IMA A;  3BWI A;  3VUO A;  2ISH A;  1G9C A;  3DDA A;  3BOO A;  1S0F A;  3C8A A;  4KS6 A;  4ZJX A;  3QIZ A;  3FIE A;  3DEB A;  3BTA A;  4KTX A;  1ZKX A;  4JIX A;  5BQN A;  1XTG A;  1ZB7 A;  1F82 A;  4ELC A;  3K3Q B;  3QIY A;  3D3X A;  3ZUS A;  3DS9 A;  3QW5 A;  2NZ9 A;  3CQB A;  2EJQ A;  5BQM A;  1ZKW A;  1G9A A;  3FFZ A;  1S0G A;  3QW8 A;  2IMC A;  3C88 A;  3QJ0 A; 
#chains in the Genus database with same CATH homology
 3QW7 A;  1S0B A;  3BON A;  2ISE A;  1ZN3 A;  2G7P A;  2FPQ A;  2XHL A;  2G7Q A;  2NYY A;  4HEV A;  1S0C A;  3BOK A;  3NF3 A;  2A97 A;  4ZKT B;  3QW6 A;  1ZL5 A;  3DDB A;  3DSE A;  4EL4 A;  3V0A B;  2W2D A;  2ISG A;  2ETF A;  1EPW A;  3V0B B;  3ZUQ A;  1F31 A;  1Z7H A;  3QIX A;  3FII A;  4EJ5 A;  1YVG A;  2ILP A;  1S0D A;  3V0A A;  4J1L A;  2QN0 A;  3C8B A;  2G7K A;  1G9D A;  3V0B A;  1E1H A;  1I1E A;  2G7N A;  1S0E A;  3ZUR A;  3C89 A;  1XTF A;  2IMB A;  2A8A A;  2NP0 A;  4KUF A;  1T3C A;  1T3A A;  1G9B A;  1ZL6 A;  2IMA A;  3BWI A;  3VUO A;  2ISH A;  1G9C A;  3DDA A;  3BOO A;  1S0F A;  3C8A A;  4KS6 A;  4ZJX A;  3QIZ A;  3FIE A;  4KTX A;  3DEB A;  3BTA A;  1ZKX A;  5BQN A;  1XTG A;  1ZB7 A;  1F82 A;  4ELC A;  3K3Q B;  3QIY A;  3D3X A;  3ZUS A;  3DS9 A;  3QW5 A;  2NZ9 A;  5BQM A;  1ZKW A;  1G9A A;  3FFZ A;  1S0G A;  3QW8 A;  2IMC A;  3C88 A;  3QJ0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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