3G4TA

Mth0212 (wt) in complex with a 7bp dsdna
Total Genus 92
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
92
sequence length
254
structure length
254
Chain Sequence
VLKIISWNVNGLRAVHRKGFLKWFMEEKPDILCLQEIKAAPEQLPRKLRHVEGYRSFFTPAERKGYSGVAMYTKVPPSSLREGFGVERFDTEGRIQIADFDDFLLYNIYFPNGKMSEERLKYKLEFYDAFLEDVNRERDSGRNVIICGDFNTAHREIDLARPKENSNVSGFLPVERAWIDKFIENGYVDTFRMFNSDPGQYTWWSYRTRARERNVGWRLDYFFVNEEFKGKVKRSWILSDVMGSDHCPIGLEIE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal Structure Analysis of DNA Uridine Endonuclease Mth212 Bound to DNA
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Methanothermobacter thermautotrophicus
molecule keywords Exodeoxyribonuclease
total genus 92
structure length 254
sequence length 254
chains with identical sequence B
ec nomenclature ec 3.1.11.2: Exodeoxyribonuclease III.
pdb deposition date 2009-02-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 3g4tA00
3I46A 4CMLA 3I48A 4F1IA 3NGOA 2V0RA 5CFGA 2V0SA 5EWTA 2A40B 3W3DB 1DNKA 5DV2A 4F1RA 5INLA 1BIXA 3MTCA 5INOA 4F1HA 1VYBA 3NR8A 4RUWA 3NGNA 3FZIA 4QH9A 1ZWXA 4B5HA 2J63A 4F1HB 3G3YA 5J42A 5DFHA 1SI6X 4GYZA 5INNA 1YJHA 5A7IA 3G2CA 1I9ZA 2JC5A 5HT2A 1NTFA 1DE8A 2DDTA 1I9YA 4L1ZA 3TEBA 2D1KB 5DFFA 4B5MA 4LNDA 4FPVA 2O3CA 4K6LF 4L20A 5INQA 1SR4B 3I5VA 3G0AA 4A9CA 5DFIA 4JG3A 3WCXA 3G38A 3G3CA 2F2FB 1Y21A 2DDRA 3U8UA 3NGQA 5J3PA 3L1WA 4L21A 5J3ZA 3W2YA 1WDUA 4IEMA 4FVAA 4L1YA 2UYRX 3G8VA 5DFJA 3K55A 4AWNA 4B5FA 3G0RA 2EI9A 4GEWA 4GZ1A 2VOAA 2DDSA 1AKOA 3G2DA 5DG0A 1ATND 2F1NA 3MPRA 3G1KA 5J8NA 3G91A 1E9NA 2IMQX 4QHEA 4PUQA 5J3SA 3N9VA 2JC4A 4C1RA 1DE9A 2O3HA 3G6SA 4GZ2A 3CJCD 3G4TA 2A3ZB 4QHDA 4CMNA 3DNIA 1DEWA 4B5JA 3W2XA 5CFEA 5DV4A 3G00A 2ISIA 2A41B 2XSWA 2DNJA 4B5GA 5A7JA 1HD7A 3I41A 5INKA 5INMA 4GZ0A 4B5IA 3GA6A 5INPA 2A42B
chains in the Genus database with same CATH superfamily
3I46A 4CMLA 3I48A 4F1IA 3NGOA 2V0RA 5CFGA 2V0SA 5EWTA 2A40B 3W3DB 1DNKA 5DV2A 4F1RA 5INLA 1BIXA 3MTCA 5INOA 4F1HA 1VYBA 3NR8A 4RUWA 3NGNA 3FZIA 4QH9A 1ZWXA 4B5HA 2J63A 4F1HB 3G3YA 5J42A 5DFHA 1SI6X 4GYZA 5INNA 1YJHA 5A7IA 3G2CA 1I9ZA 2JC5A 5HT2A 1NTFA 1DE8A 2DDTA 1I9YA 4L1ZA 3TEBA 2D1KB 5DFFA 4B5MA 4LNDA 4FPVA 2O3CA 4K6LF 4L20A 5INQA 1SR4B 3I5VA 3G0AA 4A9CA 5DFIA 4JG3A 3WCXA 3G38A 3G3CA 2F2FB 1Y21A 2DDRA 3U8UA 3NGQA 5J3PA 3L1WA 4L21A 5J3ZA 3W2YA 1WDUA 4IEMA 4FVAA 4L1YA 2UYRX 3G8VA 5DFJA 3K55A 4AWNA 4B5FA 3G0RA 2EI9A 4GEWA 4GZ1A 2VOAA 2DDSA 1AKOA 3G2DA 5DG0A 1ATND 2F1NA 3MPRA 3G1KA 5J8NA 3G91A 1E9NA 2IMQX 4QHEA 4PUQA 5J3SA 3N9VA 2JC4A 4C1RA 1DE9A 2O3HA 3G6SA 4GZ2A 3CJCD 3G4TA 2A3ZB 4QHDA 4CMNA 3DNIA 1DEWA 4B5JA 3W2XA 5CFEA 5DV4A 3G00A 2ISIA 2A41B 2XSWA 2DNJA 4B5GA 5A7JA 1HD7A 3I41A 5INKA 5INMA 4GZ0A 4B5IA 3GA6A 5INPA 2A42B
chains in the Genus database with same CATH topology
3I46A 4CMLA 3I48A 4F1IA 3NGOA 2V0RA 5CFGA 2V0SA 5EWTA 2A40B 3W3DB 1DNKA 5DV2A 4F1RA 5INLA 1BIXA 3MTCA 5INOA 4F1HA 1VYBA 3NR8A 4RUWA 3NGNA 3FZIA 4QH9A 1ZWXA 4B5HA 2J63A 4F1HB 3G3YA 5J42A 5DFHA 1SI6X 4GYZA 5INNA 1YJHA 5A7IA 3G2CA 1I9ZA 2JC5A 5HT2A 1NTFA 1DE8A 2DDTA 1I9YA 4L1ZA 3TEBA 2D1KB 5DFFA 4B5MA 4LNDA 4FPVA 2O3CA 4K6LF 4L20A 5INQA 1SR4B 3I5VA 3G0AA 4A9CA 5DFIA 4JG3A 3WCXA 3G38A 3G3CA 2F2FB 1Y21A 2DDRA 3U8UA 3NGQA 5J3PA 3L1WA 4L21A 5J3ZA 3W2YA 1WDUA 4IEMA 4FVAA 4L1YA 2UYRX 3G8VA 5DFJA 3K55A 4AWNA 4B5FA 3G0RA 2EI9A 4GEWA 4GZ1A 2VOAA 2DDSA 1AKOA 3G2DA 5DG0A 1ATND 2F1NA 3MPRA 3G1KA 5J8NA 3G91A 1E9NA 2IMQX 4QHEA 4PUQA 5J3SA 3N9VA 2JC4A 4C1RA 1DE9A 2O3HA 3G6SA 4GZ2A 3CJCD 3G4TA 2A3ZB 4QHDA 4CMNA 3DNIA 1DEWA 4B5JA 3W2XA 5CFEA 5DV4A 3G00A 2ISIA 2A41B 2XSWA 2DNJA 4B5GA 5A7JA 1HD7A 3I41A 5INKA 5INMA 4GZ0A 4B5IA 3GA6A 5INPA 2A42B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3I46 A;  4CML A;  3I48 A;  4F1I A;  3NGO A;  2V0R A;  5CFG A;  2V0S A;  5EWT A;  2A40 B;  3W3D B;  1DNK A;  5DV2 A;  4F1R A;  5INL A;  1BIX A;  3MTC A;  5INO A;  4F1H A;  1VYB A;  3NR8 A;  4RUW A;  3NGN A;  3FZI A;  4QH9 A;  1ZWX A;  4B5H A;  2J63 A;  4F1H B;  3G3Y A;  5J42 A;  5DFH A;  1SI6 X;  4GYZ A;  5INN A;  1YJH A;  5A7I A;  3G2C A;  1I9Z A;  2JC5 A;  5HT2 A;  1NTF A;  1DE8 A;  2DDT A;  1I9Y A;  4L1Z A;  3TEB A;  2D1K B;  5DFF A;  4B5M A;  4LND A;  4FPV A;  2O3C A;  4K6L F;  4L20 A;  5INQ A;  1SR4 B;  3I5V A;  3G0A A;  4A9C A;  5DFI A;  4JG3 A;  3WCX A;  3G38 A;  3G3C A;  2F2F B;  1Y21 A;  2DDR A;  3U8U A;  3NGQ A;  5J3P A;  3L1W A;  4L21 A;  5J3Z A;  3W2Y A;  1WDU A;  4IEM A;  4FVA A;  4L1Y A;  2UYR X;  3G8V A;  5DFJ A;  3K55 A;  4AWN A;  4B5F A;  3G0R A;  2EI9 A;  4GEW A;  4GZ1 A;  2VOA A;  2DDS A;  1AKO A;  3G2D A;  5DG0 A;  1ATN D;  2F1N A;  3MPR A;  3G1K A;  5J8N A;  3G91 A;  1E9N A;  2IMQ X;  4QHE A;  4PUQ A;  5J3S A;  3N9V A;  2JC4 A;  4C1R A;  1DE9 A;  2O3H A;  3G6S A;  4GZ2 A;  3CJC D;  3G4T A;  2A3Z B;  4QHD A;  4CMN A;  3DNI A;  1DEW A;  4B5J A;  3W2X A;  5CFE A;  5DV4 A;  3G00 A;  2ISI A;  2A41 B;  2XSW A;  2DNJ A;  4B5G A;  5A7J A;  1HD7 A;  3I41 A;  5INK A;  5INM A;  4GZ0 A;  4B5I A;  3GA6 A;  5INP A;  2A42 B; 
#chains in the Genus database with same CATH topology
 3I46 A;  4CML A;  3I48 A;  4F1I A;  3NGO A;  2V0R A;  5CFG A;  2V0S A;  5EWT A;  2A40 B;  3W3D B;  1DNK A;  5DV2 A;  4F1R A;  5INL A;  1BIX A;  3MTC A;  5INO A;  4F1H A;  1VYB A;  3NR8 A;  4RUW A;  3NGN A;  3FZI A;  4QH9 A;  1ZWX A;  4B5H A;  2J63 A;  4F1H B;  3G3Y A;  5J42 A;  5DFH A;  1SI6 X;  4GYZ A;  5INN A;  1YJH A;  5A7I A;  3G2C A;  1I9Z A;  2JC5 A;  5HT2 A;  1NTF A;  1DE8 A;  2DDT A;  1I9Y A;  4L1Z A;  3TEB A;  2D1K B;  5DFF A;  4B5M A;  4LND A;  4FPV A;  2O3C A;  4K6L F;  4L20 A;  5INQ A;  1SR4 B;  3I5V A;  3G0A A;  4A9C A;  5DFI A;  4JG3 A;  3WCX A;  3G38 A;  3G3C A;  2F2F B;  1Y21 A;  2DDR A;  3U8U A;  3NGQ A;  5J3P A;  3L1W A;  4L21 A;  5J3Z A;  3W2Y A;  1WDU A;  4IEM A;  4FVA A;  4L1Y A;  2UYR X;  3G8V A;  5DFJ A;  3K55 A;  4AWN A;  4B5F A;  3G0R A;  2EI9 A;  4GEW A;  4GZ1 A;  2VOA A;  2DDS A;  1AKO A;  3G2D A;  5DG0 A;  1ATN D;  2F1N A;  3MPR A;  3G1K A;  5J8N A;  3G91 A;  1E9N A;  2IMQ X;  4QHE A;  4PUQ A;  5J3S A;  3N9V A;  2JC4 A;  4C1R A;  1DE9 A;  2O3H A;  3G6S A;  4GZ2 A;  3CJC D;  3G4T A;  2A3Z B;  4QHD A;  4CMN A;  3DNI A;  1DEW A;  4B5J A;  3W2X A;  5CFE A;  5DV4 A;  3G00 A;  2ISI A;  2A41 B;  2XSW A;  2DNJ A;  4B5G A;  5A7J A;  1HD7 A;  3I41 A;  5INK A;  5INM A;  4GZ0 A;  4B5I A;  3GA6 A;  5INP A;  2A42 B; 
#chains in the Genus database with same CATH homology
 3I46 A;  4CML A;  3I48 A;  4F1I A;  3NGO A;  2V0R A;  5CFG A;  2V0S A;  5EWT A;  2A40 B;  3W3D B;  1DNK A;  5DV2 A;  4F1R A;  5INL A;  1BIX A;  3MTC A;  5INO A;  4F1H A;  1VYB A;  3NR8 A;  4RUW A;  3NGN A;  3FZI A;  4QH9 A;  1ZWX A;  4B5H A;  2J63 A;  4F1H B;  3G3Y A;  5J42 A;  5DFH A;  1SI6 X;  4GYZ A;  5INN A;  1YJH A;  5A7I A;  3G2C A;  1I9Z A;  2JC5 A;  5HT2 A;  1NTF A;  1DE8 A;  2DDT A;  1I9Y A;  4L1Z A;  3TEB A;  2D1K B;  5DFF A;  4B5M A;  4LND A;  4FPV A;  2O3C A;  4K6L F;  4L20 A;  5INQ A;  1SR4 B;  3I5V A;  3G0A A;  4A9C A;  5DFI A;  4JG3 A;  3WCX A;  3G38 A;  3G3C A;  2F2F B;  1Y21 A;  2DDR A;  3U8U A;  3NGQ A;  5J3P A;  3L1W A;  4L21 A;  5J3Z A;  3W2Y A;  1WDU A;  4IEM A;  4FVA A;  4L1Y A;  2UYR X;  3G8V A;  5DFJ A;  3K55 A;  4AWN A;  4B5F A;  3G0R A;  2EI9 A;  4GEW A;  4GZ1 A;  2VOA A;  2DDS A;  1AKO A;  3G2D A;  5DG0 A;  1ATN D;  2F1N A;  3MPR A;  3G1K A;  5J8N A;  3G91 A;  1E9N A;  2IMQ X;  4QHE A;  4PUQ A;  5J3S A;  3N9V A;  2JC4 A;  4C1R A;  1DE9 A;  2O3H A;  3G6S A;  4GZ2 A;  3CJC D;  3G4T A;  2A3Z B;  4QHD A;  4CMN A;  3DNI A;  1DEW A;  4B5J A;  3W2X A;  5CFE A;  5DV4 A;  3G00 A;  2ISI A;  2A41 B;  2XSW A;  2DNJ A;  4B5G A;  5A7J A;  1HD7 A;  3I41 A;  5INK A;  5INM A;  4GZ0 A;  4B5I A;  3GA6 A;  5INP A;  2A42 B; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...