3G8VA

The rationally designed catalytically inactive mutant mth0212(d151n)
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
255
structure length
255
Chain Sequence
AVLKIISWNVNGLRAVHRKGFLKWFMEEKPDILCLQEIKAAPEQLPRKLRHVEGYRSFFTPAERKGYSGVAMYTKVPPSSLREGFGVERFDTEGRIQIADFDDFLLYNIYFPNGKMSEERLKYKLEFYDAFLEDVNRERDSGRNVIICGNFNTAHREIDLARPKENSNVSGFLPVERAWIDKFIENGYVDTFRMFNSDPGQYTWWSYRTRARERNVGWRLDYFFVNEEFKGKVKRSWILSDVMGSDHCPIGLEIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Methanothermobacter thermautotrophicus
publication title Crystal Structure Analysis of DNA Uridine Endonuclease Mth212 Bound to DNA
pubmed doi rcsb
molecule keywords Exodeoxyribonuclease
total genus 86
structure length 255
sequence length 255
ec nomenclature ec 3.1.11.2: Exodeoxyribonuclease III.
pdb deposition date 2009-02-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 3g8vA00
4F1IA 2O3HA 1DNKA 4K6LF 3W3DB 2UYRX 2J63A 1DE9A 5INMA 4L21A 4B5JA 5EWTA 3G0RA 1DE8A 5INNA 2O3CA 2F1NA 3NGQA 5CFEA 3NGNA 1HD7A 2DDRA 1NTFA 3NGOA 4GZ0A 4C1RA 5A7JA 2DDSA 4F1HB 4B5MA 4GZ1A 4B5HA 1ATND 5DFFA 4A9CA 3NR8A 3W2YA 4AWNA 2V0SA 1E9NA 5J42A 1SR4B 1YJHA 2D1KB 2VOAA 3CJCD 3W2XA 4B5GA 4GYZA 3G00A 4GZ2A 3K55A 2IMQX 1I9YA 3I48A 5J3SA 4L1YA 2DDTA 3G8VA 3U8UA 4RUWA 5INPA 3WCXA 3GA6A 3G1KA 5INKA 3G38A 3DNIA 5DG0A 5INLA 4CMLA 3G6SA 3I5VA 5DFJA 4QHEA 3I46A 2A42B 1SI6X 1DEWA 5DV2A 1Y21A 1I9ZA 5DFIA 3G4TA 2DNJA 2V0RA 2F2FB 4QH9A 3G2CA 5CFGA 5INOA 5DFHA 5DV4A 2A3ZB 2A40B 2JC4A 4L20A 3L1WA 4F1HA 1WDUA 4GEWA 2A41B 3MPRA 3G3YA 3I41A 3FZIA 2XSWA 5INQA 3G2DA 5J3PA 3G0AA 3G91A 4LNDA 4B5FA 4FPVA 4B5IA 2JC5A 1AKOA 1BIXA 5A7IA 2EI9A 4QHDA 4JG3A 4IEMA 3MTCA 1ZWXA 4FVAA 3TEBA 5J8NA 1VYBA 2ISIA 4PUQA 4L1ZA 5J3ZA 4F1RA 3G3CA 5HT2A 3N9VA 4CMNA
chains in the Genus database with same CATH superfamily
4F1IA 2O3HA 1DNKA 4K6LF 3W3DB 2UYRX 2J63A 1DE9A 5INMA 4L21A 4B5JA 5EWTA 3G0RA 1DE8A 5INNA 2O3CA 2F1NA 3NGQA 5CFEA 3NGNA 1HD7A 2DDRA 1NTFA 3NGOA 4GZ0A 4C1RA 5A7JA 2DDSA 4F1HB 4B5MA 4GZ1A 4B5HA 1ATND 5DFFA 4A9CA 3NR8A 3W2YA 4AWNA 2V0SA 1E9NA 5J42A 1SR4B 1YJHA 2D1KB 2VOAA 3CJCD 3W2XA 4B5GA 4GYZA 3G00A 4GZ2A 3K55A 2IMQX 1I9YA 3I48A 5J3SA 4L1YA 2DDTA 3G8VA 3U8UA 4RUWA 5INPA 3WCXA 3GA6A 3G1KA 5INKA 3G38A 3DNIA 5DG0A 5INLA 4CMLA 3G6SA 3I5VA 5DFJA 4QHEA 3I46A 2A42B 1SI6X 1DEWA 5DV2A 1Y21A 1I9ZA 5DFIA 3G4TA 2DNJA 2V0RA 2F2FB 4QH9A 3G2CA 5CFGA 5INOA 5DFHA 5DV4A 2A3ZB 2A40B 2JC4A 4L20A 3L1WA 4F1HA 1WDUA 4GEWA 2A41B 3MPRA 3G3YA 3I41A 3FZIA 2XSWA 5INQA 3G2DA 5J3PA 3G0AA 3G91A 4LNDA 4B5FA 4FPVA 4B5IA 2JC5A 1AKOA 1BIXA 5A7IA 2EI9A 4QHDA 4JG3A 4IEMA 3MTCA 1ZWXA 4FVAA 3TEBA 5J8NA 1VYBA 2ISIA 4PUQA 4L1ZA 5J3ZA 4F1RA 3G3CA 5HT2A 3N9VA 4CMNA
chains in the Genus database with same CATH topology
4F1IA 2O3HA 1DNKA 4K6LF 3W3DB 2UYRX 2J63A 1DE9A 5INMA 4L21A 4B5JA 5EWTA 3G0RA 1DE8A 5INNA 2O3CA 2F1NA 3NGQA 5CFEA 3NGNA 1HD7A 2DDRA 1NTFA 3NGOA 4GZ0A 4C1RA 5A7JA 2DDSA 4F1HB 4B5MA 4GZ1A 4B5HA 1ATND 5DFFA 4A9CA 3NR8A 3W2YA 4AWNA 2V0SA 1E9NA 5J42A 1SR4B 1YJHA 2D1KB 2VOAA 3CJCD 3W2XA 4B5GA 4GYZA 3G00A 4GZ2A 3K55A 2IMQX 1I9YA 3I48A 5J3SA 4L1YA 2DDTA 3G8VA 3U8UA 4RUWA 5INPA 3WCXA 3GA6A 3G1KA 5INKA 3G38A 3DNIA 5DG0A 5INLA 4CMLA 3G6SA 3I5VA 5DFJA 4QHEA 3I46A 2A42B 1SI6X 1DEWA 5DV2A 1Y21A 1I9ZA 5DFIA 3G4TA 2DNJA 2V0RA 2F2FB 4QH9A 3G2CA 5CFGA 5INOA 5DFHA 5DV4A 2A3ZB 2A40B 2JC4A 4L20A 3L1WA 4F1HA 1WDUA 4GEWA 2A41B 3MPRA 3G3YA 3I41A 3FZIA 2XSWA 5INQA 3G2DA 5J3PA 3G0AA 3G91A 4LNDA 4B5FA 4FPVA 4B5IA 2JC5A 1AKOA 1BIXA 5A7IA 2EI9A 4QHDA 4JG3A 4IEMA 3MTCA 1ZWXA 4FVAA 3TEBA 5J8NA 1VYBA 2ISIA 4PUQA 4L1ZA 5J3ZA 4F1RA 3G3CA 5HT2A 3N9VA 4CMNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4F1I A;  2O3H A;  1DNK A;  4K6L F;  3W3D B;  2UYR X;  2J63 A;  1DE9 A;  5INM A;  4L21 A;  4B5J A;  5EWT A;  3G0R A;  1DE8 A;  5INN A;  2O3C A;  2F1N A;  3NGQ A;  5CFE A;  3NGN A;  1HD7 A;  2DDR A;  1NTF A;  3NGO A;  4GZ0 A;  4C1R A;  5A7J A;  2DDS A;  4F1H B;  4B5M A;  4GZ1 A;  4B5H A;  1ATN D;  5DFF A;  4A9C A;  3NR8 A;  3W2Y A;  4AWN A;  2V0S A;  1E9N A;  5J42 A;  1SR4 B;  1YJH A;  2D1K B;  2VOA A;  3CJC D;  3W2X A;  4B5G A;  4GYZ A;  3G00 A;  4GZ2 A;  3K55 A;  2IMQ X;  1I9Y A;  3I48 A;  5J3S A;  4L1Y A;  2DDT A;  3G8V A;  3U8U A;  4RUW A;  5INP A;  3WCX A;  3GA6 A;  3G1K A;  5INK A;  3G38 A;  3DNI A;  5DG0 A;  5INL A;  4CML A;  3G6S A;  3I5V A;  5DFJ A;  4QHE A;  3I46 A;  2A42 B;  1SI6 X;  1DEW A;  5DV2 A;  1Y21 A;  1I9Z A;  5DFI A;  3G4T A;  2DNJ A;  2V0R A;  2F2F B;  4QH9 A;  3G2C A;  5CFG A;  5INO A;  5DFH A;  5DV4 A;  2A3Z B;  2A40 B;  2JC4 A;  4L20 A;  3L1W A;  4F1H A;  1WDU A;  4GEW A;  2A41 B;  3MPR A;  3G3Y A;  3I41 A;  3FZI A;  2XSW A;  5INQ A;  3G2D A;  5J3P A;  3G0A A;  3G91 A;  4LND A;  4B5F A;  4FPV A;  4B5I A;  2JC5 A;  1AKO A;  1BIX A;  5A7I A;  2EI9 A;  4QHD A;  4JG3 A;  4IEM A;  3MTC A;  1ZWX A;  4FVA A;  3TEB A;  5J8N A;  1VYB A;  2ISI A;  4PUQ A;  4L1Z A;  5J3Z A;  4F1R A;  3G3C A;  5HT2 A;  3N9V A;  4CMN A; 
#chains in the Genus database with same CATH topology
 4F1I A;  2O3H A;  1DNK A;  4K6L F;  3W3D B;  2UYR X;  2J63 A;  1DE9 A;  5INM A;  4L21 A;  4B5J A;  5EWT A;  3G0R A;  1DE8 A;  5INN A;  2O3C A;  2F1N A;  3NGQ A;  5CFE A;  3NGN A;  1HD7 A;  2DDR A;  1NTF A;  3NGO A;  4GZ0 A;  4C1R A;  5A7J A;  2DDS A;  4F1H B;  4B5M A;  4GZ1 A;  4B5H A;  1ATN D;  5DFF A;  4A9C A;  3NR8 A;  3W2Y A;  4AWN A;  2V0S A;  1E9N A;  5J42 A;  1SR4 B;  1YJH A;  2D1K B;  2VOA A;  3CJC D;  3W2X A;  4B5G A;  4GYZ A;  3G00 A;  4GZ2 A;  3K55 A;  2IMQ X;  1I9Y A;  3I48 A;  5J3S A;  4L1Y A;  2DDT A;  3G8V A;  3U8U A;  4RUW A;  5INP A;  3WCX A;  3GA6 A;  3G1K A;  5INK A;  3G38 A;  3DNI A;  5DG0 A;  5INL A;  4CML A;  3G6S A;  3I5V A;  5DFJ A;  4QHE A;  3I46 A;  2A42 B;  1SI6 X;  1DEW A;  5DV2 A;  1Y21 A;  1I9Z A;  5DFI A;  3G4T A;  2DNJ A;  2V0R A;  2F2F B;  4QH9 A;  3G2C A;  5CFG A;  5INO A;  5DFH A;  5DV4 A;  2A3Z B;  2A40 B;  2JC4 A;  4L20 A;  3L1W A;  4F1H A;  1WDU A;  4GEW A;  2A41 B;  3MPR A;  3G3Y A;  3I41 A;  3FZI A;  2XSW A;  5INQ A;  3G2D A;  5J3P A;  3G0A A;  3G91 A;  4LND A;  4B5F A;  4FPV A;  4B5I A;  2JC5 A;  1AKO A;  1BIX A;  5A7I A;  2EI9 A;  4QHD A;  4JG3 A;  4IEM A;  3MTC A;  1ZWX A;  4FVA A;  3TEB A;  5J8N A;  1VYB A;  2ISI A;  4PUQ A;  4L1Z A;  5J3Z A;  4F1R A;  3G3C A;  5HT2 A;  3N9V A;  4CMN A; 
#chains in the Genus database with same CATH homology
 4F1I A;  2O3H A;  1DNK A;  4K6L F;  3W3D B;  2UYR X;  2J63 A;  1DE9 A;  5INM A;  4L21 A;  4B5J A;  5EWT A;  3G0R A;  1DE8 A;  5INN A;  2O3C A;  2F1N A;  3NGQ A;  5CFE A;  3NGN A;  1HD7 A;  2DDR A;  1NTF A;  3NGO A;  4GZ0 A;  4C1R A;  5A7J A;  2DDS A;  4F1H B;  4B5M A;  4GZ1 A;  4B5H A;  1ATN D;  5DFF A;  4A9C A;  3NR8 A;  3W2Y A;  4AWN A;  2V0S A;  1E9N A;  5J42 A;  1SR4 B;  1YJH A;  2D1K B;  2VOA A;  3CJC D;  3W2X A;  4B5G A;  4GYZ A;  3G00 A;  4GZ2 A;  3K55 A;  2IMQ X;  1I9Y A;  3I48 A;  5J3S A;  4L1Y A;  2DDT A;  3G8V A;  3U8U A;  4RUW A;  5INP A;  3WCX A;  3GA6 A;  3G1K A;  5INK A;  3G38 A;  3DNI A;  5DG0 A;  5INL A;  4CML A;  3G6S A;  3I5V A;  5DFJ A;  4QHE A;  3I46 A;  2A42 B;  1SI6 X;  1DEW A;  5DV2 A;  1Y21 A;  1I9Z A;  5DFI A;  3G4T A;  2DNJ A;  2V0R A;  2F2F B;  4QH9 A;  3G2C A;  5CFG A;  5INO A;  5DFH A;  5DV4 A;  2A3Z B;  2A40 B;  2JC4 A;  4L20 A;  3L1W A;  4F1H A;  1WDU A;  4GEW A;  2A41 B;  3MPR A;  3G3Y A;  3I41 A;  3FZI A;  2XSW A;  5INQ A;  3G2D A;  5J3P A;  3G0A A;  3G91 A;  4LND A;  4B5F A;  4FPV A;  4B5I A;  2JC5 A;  1AKO A;  1BIX A;  5A7I A;  2EI9 A;  4QHD A;  4JG3 A;  4IEM A;  3MTC A;  1ZWX A;  4FVA A;  3TEB A;  5J8N A;  1VYB A;  2ISI A;  4PUQ A;  4L1Z A;  5J3Z A;  4F1R A;  3G3C A;  5HT2 A;  3N9V A;  4CMN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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