3MTCA

Crystal structure of inpp5b in complex with phosphatidylinositol 4-phosphate
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
310
structure length
310
Chain Sequence
MYTYIQNFRFFAGTYNVNGQSPKECLRLWLSNGIQAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPLTISNHDVILWLGDLNYRIEELDVEKVKKLIEEKDFQMLYAYDQLKIQVAAKTVFEGFTEGELTFQPTYKYDTGSDDWDTSEKCRAPAWCDRILWKGKNITQLSYQSHMALKTSDHKPVSSVFDIGVRVVAHHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
publication title Structural basis for phosphoinositide substrate recognition, catalysis, and membrane interactions in human inositol polyphosphate 5-phosphatases
pubmed doi rcsb
molecule keywords Type II inositol-1,4,5-trisphosphate 5-phosphatase
total genus 94
structure length 310
sequence length 310
ec nomenclature ec 3.1.3.36: Phosphoinositide 5-phosphatase.
pdb deposition date 2010-04-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 3mtcA00
4L1YA 2ISIA 3G1KA 4F1IA 4A9CA 4B5IA 4CMNA 2A3ZB 3GA6A 1NTFA 3G38A 2A41B 4CMLA 3G91A 1BIXA 2JC4A 4PUQA 4B5JA 5J3ZA 3MPRA 5HT2A 1SR4B 3I46A 5INPA 2DDSA 4FVAA 3G2CA 3TEBA 4GEWA 2A42B 4C1RA 1Y21A 5INNA 1DE8A 3NGOA 5A7JA 3WCXA 5DG0A 3W2XA 4GYZA 4GZ2A 2DDRA 5INLA 3I48A 3W2YA 1YJHA 2V0SA 3I5VA 3G3CA 3G6SA 4RUWA 5INOA 3CJCD 1I9YA 2JC5A 4K6LF 3DNIA 3K55A 4AWNA 4GZ0A 1VYBA 4L20A 2UYRX 3MTCA 2O3HA 4GZ1A 3W3DB 2F2FB 4FPVA 4IEMA 2O3CA 4F1HB 4F1RA 5DV2A 1ATND 2D1KB 3NR8A 4L21A 3NGNA 2J63A 3NGQA 5INMA 5J8NA 3FZIA 3G4TA 1I9ZA 2DDTA 5INKA 4L1ZA 5J42A 4B5MA 2EI9A 5DFHA 3I41A 4B5GA 2XSWA 1DE9A 4QHDA 5J3PA 1AKOA 4QH9A 4QHEA 4B5HA 3G0RA 3G00A 2DNJA 3L1WA 5DV4A 5INQA 3G2DA 5A7IA 4F1HA 1DNKA 2VOAA 5CFGA 1HD7A 5J3SA 2A40B 5EWTA 2IMQX 4LNDA 1DEWA 3N9VA 3G0AA 2F1NA 1E9NA 4B5FA 5DFIA 5DFFA 3U8UA 3G3YA 2V0RA 3G8VA 1ZWXA 5DFJA 5CFEA 1SI6X 4JG3A 1WDUA
chains in the Genus database with same CATH superfamily
4L1YA 2ISIA 3G1KA 4F1IA 4A9CA 4B5IA 4CMNA 2A3ZB 3GA6A 1NTFA 3G38A 2A41B 4CMLA 3G91A 1BIXA 2JC4A 4PUQA 4B5JA 5J3ZA 3MPRA 5HT2A 1SR4B 3I46A 5INPA 2DDSA 4FVAA 3G2CA 3TEBA 4GEWA 2A42B 4C1RA 1Y21A 5INNA 1DE8A 3NGOA 5A7JA 3WCXA 5DG0A 3W2XA 4GYZA 4GZ2A 2DDRA 5INLA 3I48A 3W2YA 1YJHA 2V0SA 3I5VA 3G3CA 3G6SA 4RUWA 5INOA 3CJCD 1I9YA 2JC5A 4K6LF 3DNIA 3K55A 4AWNA 4GZ0A 1VYBA 4L20A 2UYRX 3MTCA 2O3HA 4GZ1A 3W3DB 2F2FB 4FPVA 4IEMA 2O3CA 4F1HB 4F1RA 5DV2A 1ATND 2D1KB 3NR8A 4L21A 3NGNA 2J63A 3NGQA 5INMA 5J8NA 3FZIA 3G4TA 1I9ZA 2DDTA 5INKA 4L1ZA 5J42A 4B5MA 2EI9A 5DFHA 3I41A 4B5GA 2XSWA 1DE9A 4QHDA 5J3PA 1AKOA 4QH9A 4QHEA 4B5HA 3G0RA 3G00A 2DNJA 3L1WA 5DV4A 5INQA 3G2DA 5A7IA 4F1HA 1DNKA 2VOAA 5CFGA 1HD7A 5J3SA 2A40B 5EWTA 2IMQX 4LNDA 1DEWA 3N9VA 3G0AA 2F1NA 1E9NA 4B5FA 5DFIA 5DFFA 3U8UA 3G3YA 2V0RA 3G8VA 1ZWXA 5DFJA 5CFEA 1SI6X 4JG3A 1WDUA
chains in the Genus database with same CATH topology
4L1YA 2ISIA 3G1KA 4F1IA 4A9CA 4B5IA 4CMNA 2A3ZB 3GA6A 1NTFA 3G38A 2A41B 4CMLA 3G91A 1BIXA 2JC4A 4PUQA 4B5JA 5J3ZA 3MPRA 5HT2A 1SR4B 3I46A 5INPA 2DDSA 4FVAA 3G2CA 3TEBA 4GEWA 2A42B 4C1RA 1Y21A 5INNA 1DE8A 3NGOA 5A7JA 3WCXA 5DG0A 3W2XA 4GYZA 4GZ2A 2DDRA 5INLA 3I48A 3W2YA 1YJHA 2V0SA 3I5VA 3G3CA 3G6SA 4RUWA 5INOA 3CJCD 1I9YA 2JC5A 4K6LF 3DNIA 3K55A 4AWNA 4GZ0A 1VYBA 4L20A 2UYRX 3MTCA 2O3HA 4GZ1A 3W3DB 2F2FB 4FPVA 4IEMA 2O3CA 4F1HB 4F1RA 5DV2A 1ATND 2D1KB 3NR8A 4L21A 3NGNA 2J63A 3NGQA 5INMA 5J8NA 3FZIA 3G4TA 1I9ZA 2DDTA 5INKA 4L1ZA 5J42A 4B5MA 2EI9A 5DFHA 3I41A 4B5GA 2XSWA 1DE9A 4QHDA 5J3PA 1AKOA 4QH9A 4QHEA 4B5HA 3G0RA 3G00A 2DNJA 3L1WA 5DV4A 5INQA 3G2DA 5A7IA 4F1HA 1DNKA 2VOAA 5CFGA 1HD7A 5J3SA 2A40B 5EWTA 2IMQX 4LNDA 1DEWA 3N9VA 3G0AA 2F1NA 1E9NA 4B5FA 5DFIA 5DFFA 3U8UA 3G3YA 2V0RA 3G8VA 1ZWXA 5DFJA 5CFEA 1SI6X 4JG3A 1WDUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4L1Y A;  2ISI A;  3G1K A;  4F1I A;  4A9C A;  4B5I A;  4CMN A;  2A3Z B;  3GA6 A;  1NTF A;  3G38 A;  2A41 B;  4CML A;  3G91 A;  1BIX A;  2JC4 A;  4PUQ A;  4B5J A;  5J3Z A;  3MPR A;  5HT2 A;  1SR4 B;  3I46 A;  5INP A;  2DDS A;  4FVA A;  3G2C A;  3TEB A;  4GEW A;  2A42 B;  4C1R A;  1Y21 A;  5INN A;  1DE8 A;  3NGO A;  5A7J A;  3WCX A;  5DG0 A;  3W2X A;  4GYZ A;  4GZ2 A;  2DDR A;  5INL A;  3I48 A;  3W2Y A;  1YJH A;  2V0S A;  3I5V A;  3G3C A;  3G6S A;  4RUW A;  5INO A;  3CJC D;  1I9Y A;  2JC5 A;  4K6L F;  3DNI A;  3K55 A;  4AWN A;  4GZ0 A;  1VYB A;  4L20 A;  2UYR X;  3MTC A;  2O3H A;  4GZ1 A;  3W3D B;  2F2F B;  4FPV A;  4IEM A;  2O3C A;  4F1H B;  4F1R A;  5DV2 A;  1ATN D;  2D1K B;  3NR8 A;  4L21 A;  3NGN A;  2J63 A;  3NGQ A;  5INM A;  5J8N A;  3FZI A;  3G4T A;  1I9Z A;  2DDT A;  5INK A;  4L1Z A;  5J42 A;  4B5M A;  2EI9 A;  5DFH A;  3I41 A;  4B5G A;  2XSW A;  1DE9 A;  4QHD A;  5J3P A;  1AKO A;  4QH9 A;  4QHE A;  4B5H A;  3G0R A;  3G00 A;  2DNJ A;  3L1W A;  5DV4 A;  5INQ A;  3G2D A;  5A7I A;  4F1H A;  1DNK A;  2VOA A;  5CFG A;  1HD7 A;  5J3S A;  2A40 B;  5EWT A;  2IMQ X;  4LND A;  1DEW A;  3N9V A;  3G0A A;  2F1N A;  1E9N A;  4B5F A;  5DFI A;  5DFF A;  3U8U A;  3G3Y A;  2V0R A;  3G8V A;  1ZWX A;  5DFJ A;  5CFE A;  1SI6 X;  4JG3 A;  1WDU A; 
#chains in the Genus database with same CATH topology
 4L1Y A;  2ISI A;  3G1K A;  4F1I A;  4A9C A;  4B5I A;  4CMN A;  2A3Z B;  3GA6 A;  1NTF A;  3G38 A;  2A41 B;  4CML A;  3G91 A;  1BIX A;  2JC4 A;  4PUQ A;  4B5J A;  5J3Z A;  3MPR A;  5HT2 A;  1SR4 B;  3I46 A;  5INP A;  2DDS A;  4FVA A;  3G2C A;  3TEB A;  4GEW A;  2A42 B;  4C1R A;  1Y21 A;  5INN A;  1DE8 A;  3NGO A;  5A7J A;  3WCX A;  5DG0 A;  3W2X A;  4GYZ A;  4GZ2 A;  2DDR A;  5INL A;  3I48 A;  3W2Y A;  1YJH A;  2V0S A;  3I5V A;  3G3C A;  3G6S A;  4RUW A;  5INO A;  3CJC D;  1I9Y A;  2JC5 A;  4K6L F;  3DNI A;  3K55 A;  4AWN A;  4GZ0 A;  1VYB A;  4L20 A;  2UYR X;  3MTC A;  2O3H A;  4GZ1 A;  3W3D B;  2F2F B;  4FPV A;  4IEM A;  2O3C A;  4F1H B;  4F1R A;  5DV2 A;  1ATN D;  2D1K B;  3NR8 A;  4L21 A;  3NGN A;  2J63 A;  3NGQ A;  5INM A;  5J8N A;  3FZI A;  3G4T A;  1I9Z A;  2DDT A;  5INK A;  4L1Z A;  5J42 A;  4B5M A;  2EI9 A;  5DFH A;  3I41 A;  4B5G A;  2XSW A;  1DE9 A;  4QHD A;  5J3P A;  1AKO A;  4QH9 A;  4QHE A;  4B5H A;  3G0R A;  3G00 A;  2DNJ A;  3L1W A;  5DV4 A;  5INQ A;  3G2D A;  5A7I A;  4F1H A;  1DNK A;  2VOA A;  5CFG A;  1HD7 A;  5J3S A;  2A40 B;  5EWT A;  2IMQ X;  4LND A;  1DEW A;  3N9V A;  3G0A A;  2F1N A;  1E9N A;  4B5F A;  5DFI A;  5DFF A;  3U8U A;  3G3Y A;  2V0R A;  3G8V A;  1ZWX A;  5DFJ A;  5CFE A;  1SI6 X;  4JG3 A;  1WDU A; 
#chains in the Genus database with same CATH homology
 4L1Y A;  2ISI A;  3G1K A;  4F1I A;  4A9C A;  4B5I A;  4CMN A;  2A3Z B;  3GA6 A;  1NTF A;  3G38 A;  2A41 B;  4CML A;  3G91 A;  1BIX A;  2JC4 A;  4PUQ A;  4B5J A;  5J3Z A;  3MPR A;  5HT2 A;  1SR4 B;  3I46 A;  5INP A;  2DDS A;  4FVA A;  3G2C A;  3TEB A;  4GEW A;  2A42 B;  4C1R A;  1Y21 A;  5INN A;  1DE8 A;  3NGO A;  5A7J A;  3WCX A;  5DG0 A;  3W2X A;  4GYZ A;  4GZ2 A;  2DDR A;  5INL A;  3I48 A;  3W2Y A;  1YJH A;  2V0S A;  3I5V A;  3G3C A;  3G6S A;  4RUW A;  5INO A;  3CJC D;  1I9Y A;  2JC5 A;  4K6L F;  3DNI A;  3K55 A;  4AWN A;  4GZ0 A;  1VYB A;  4L20 A;  2UYR X;  3MTC A;  2O3H A;  4GZ1 A;  3W3D B;  2F2F B;  4FPV A;  4IEM A;  2O3C A;  4F1H B;  4F1R A;  5DV2 A;  1ATN D;  2D1K B;  3NR8 A;  4L21 A;  3NGN A;  2J63 A;  3NGQ A;  5INM A;  5J8N A;  3FZI A;  3G4T A;  1I9Z A;  2DDT A;  5INK A;  4L1Z A;  5J42 A;  4B5M A;  2EI9 A;  5DFH A;  3I41 A;  4B5G A;  2XSW A;  1DE9 A;  4QHD A;  5J3P A;  1AKO A;  4QH9 A;  4QHE A;  4B5H A;  3G0R A;  3G00 A;  2DNJ A;  3L1W A;  5DV4 A;  5INQ A;  3G2D A;  5A7I A;  4F1H A;  1DNK A;  2VOA A;  5CFG A;  1HD7 A;  5J3S A;  2A40 B;  5EWT A;  2IMQ X;  4LND A;  1DEW A;  3N9V A;  3G0A A;  2F1N A;  1E9N A;  4B5F A;  5DFI A;  5DFF A;  3U8U A;  3G3Y A;  2V0R A;  3G8V A;  1ZWX A;  5DFJ A;  5CFE A;  1SI6 X;  4JG3 A;  1WDU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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