3WCXA

Crystal structure of sphingomyelinase c from streptomyces griseocarneus
Total Genus 99
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
292
structure length
291
Chain Sequence
TPSLKVLTYNTFLMSTGLYPNWGQEHRAREIAAAGFFQGNDVVVLQEAFDNAAADGLKAAAADRYPYQTPVVGRSRDGWDATGGKYSATTPEDGGVTVLSKWPIVRKEQVIFNDACGADWWSNKGFAYVVLNVGGTRVHVVGTHAQSTDSGCAAGEAAADRSRQFRQIDAFLDAKNIPADEQVMLAGDLNVDSHSAEYASMLADGDLAPADSRAGHPYSFDTKENSIAAYRYPTDPREDLDYVLHRNGHARPAGWRNTVVQETSAPWTVSSWKRYTYTDLSGHYPVIAGAN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Streptomyces griseocarneus
publication title Crystal Structure of Sphingomyelinase C from Streptomyces griseocarneus
rcsb
molecule keywords Sphingomyelinase C
total genus 99
structure length 291
sequence length 292
ec nomenclature ec 3.1.4.12: Sphingomyelin phosphodiesterase.
pdb deposition date 2013-06-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 3wcxA00
4AWNA 1YJHA 2F2FB 4CMLA 2V0SA 5J3SA 2A41B 5CFGA 1VYBA 3G4TA 2A42B 3G3YA 4FVAA 2JC5A 3G6SA 2IMQX 3NGNA 4FPVA 3G91A 3TEBA 4B5MA 4GEWA 2UYRX 5DFHA 2DNJA 4L1ZA 2JC4A 1ZWXA 2DDSA 2DDTA 3G38A 1I9ZA 1DEWA 1HD7A 4K6LF 1BIXA 3CJCD 3G8VA 1AKOA 3GA6A 4PUQA 3DNIA 3U8UA 4F1HA 5DV2A 4B5FA 5CFEA 2VOAA 3G0RA 3I48A 5DFFA 5INMA 1ATND 4CMNA 1I9YA 4B5GA 1NTFA 4F1HB 4L1YA 3NGQA 3N9VA 3G2CA 3W3DB 1WDUA 4B5HA 4GZ2A 2A3ZB 1DE8A 5J3PA 3I41A 5A7IA 2O3CA 3MTCA 3L1WA 4L21A 1Y21A 3G2DA 4B5IA 2ISIA 5INKA 4F1RA 5EWTA 4QH9A 4GZ1A 3G0AA 5J42A 3G3CA 5A7JA 2A40B 3NGOA 2DDRA 2F1NA 3G1KA 3I5VA 4LNDA 5INLA 5J8NA 5INNA 5DV4A 4RUWA 4GYZA 4F1IA 5INPA 1E9NA 1SI6X 3I46A 4B5JA 4QHDA 5DFIA 2O3HA 3W2YA 4QHEA 5HT2A 3MPRA 2J63A 5DFJA 3K55A 4L20A 3NR8A 5DG0A 3FZIA 5J3ZA 1SR4B 2V0RA 4IEMA 4JG3A 3WCXA 1DE9A 1DNKA 4A9CA 5INQA 2EI9A 3G00A 4GZ0A 4C1RA 3W2XA 2XSWA 5INOA 2D1KB
chains in the Genus database with same CATH superfamily
4AWNA 1YJHA 2F2FB 4CMLA 2V0SA 5J3SA 2A41B 5CFGA 1VYBA 3G4TA 2A42B 3G3YA 4FVAA 2JC5A 3G6SA 2IMQX 3NGNA 4FPVA 3G91A 3TEBA 4B5MA 4GEWA 2UYRX 5DFHA 2DNJA 4L1ZA 2JC4A 1ZWXA 2DDSA 2DDTA 3G38A 1I9ZA 1DEWA 1HD7A 4K6LF 1BIXA 3CJCD 3G8VA 1AKOA 3GA6A 4PUQA 3DNIA 3U8UA 4F1HA 5DV2A 4B5FA 5CFEA 2VOAA 3G0RA 3I48A 5DFFA 5INMA 1ATND 4CMNA 1I9YA 4B5GA 1NTFA 4F1HB 4L1YA 3NGQA 3N9VA 3G2CA 3W3DB 1WDUA 4B5HA 4GZ2A 2A3ZB 1DE8A 5J3PA 3I41A 5A7IA 2O3CA 3MTCA 3L1WA 4L21A 1Y21A 3G2DA 4B5IA 2ISIA 5INKA 4F1RA 5EWTA 4QH9A 4GZ1A 3G0AA 5J42A 3G3CA 5A7JA 2A40B 3NGOA 2DDRA 2F1NA 3G1KA 3I5VA 4LNDA 5INLA 5J8NA 5INNA 5DV4A 4RUWA 4GYZA 4F1IA 5INPA 1E9NA 1SI6X 3I46A 4B5JA 4QHDA 5DFIA 2O3HA 3W2YA 4QHEA 5HT2A 3MPRA 2J63A 5DFJA 3K55A 4L20A 3NR8A 5DG0A 3FZIA 5J3ZA 1SR4B 2V0RA 4IEMA 4JG3A 3WCXA 1DE9A 1DNKA 4A9CA 5INQA 2EI9A 3G00A 4GZ0A 4C1RA 3W2XA 2XSWA 5INOA 2D1KB
chains in the Genus database with same CATH topology
4AWNA 1YJHA 2F2FB 4CMLA 2V0SA 5J3SA 2A41B 5CFGA 1VYBA 3G4TA 2A42B 3G3YA 4FVAA 2JC5A 3G6SA 2IMQX 3NGNA 4FPVA 3G91A 3TEBA 4B5MA 4GEWA 2UYRX 5DFHA 2DNJA 4L1ZA 2JC4A 1ZWXA 2DDSA 2DDTA 3G38A 1I9ZA 1DEWA 1HD7A 4K6LF 1BIXA 3CJCD 3G8VA 1AKOA 3GA6A 4PUQA 3DNIA 3U8UA 4F1HA 5DV2A 4B5FA 5CFEA 2VOAA 3G0RA 3I48A 5DFFA 5INMA 1ATND 4CMNA 1I9YA 4B5GA 1NTFA 4F1HB 4L1YA 3NGQA 3N9VA 3G2CA 3W3DB 1WDUA 4B5HA 4GZ2A 2A3ZB 1DE8A 5J3PA 3I41A 5A7IA 2O3CA 3MTCA 3L1WA 4L21A 1Y21A 3G2DA 4B5IA 2ISIA 5INKA 4F1RA 5EWTA 4QH9A 4GZ1A 3G0AA 5J42A 3G3CA 5A7JA 2A40B 3NGOA 2DDRA 2F1NA 3G1KA 3I5VA 4LNDA 5INLA 5J8NA 5INNA 5DV4A 4RUWA 4GYZA 4F1IA 5INPA 1E9NA 1SI6X 3I46A 4B5JA 4QHDA 5DFIA 2O3HA 3W2YA 4QHEA 5HT2A 3MPRA 2J63A 5DFJA 3K55A 4L20A 3NR8A 5DG0A 3FZIA 5J3ZA 1SR4B 2V0RA 4IEMA 4JG3A 3WCXA 1DE9A 1DNKA 4A9CA 5INQA 2EI9A 3G00A 4GZ0A 4C1RA 3W2XA 2XSWA 5INOA 2D1KB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AWN A;  1YJH A;  2F2F B;  4CML A;  2V0S A;  5J3S A;  2A41 B;  5CFG A;  1VYB A;  3G4T A;  2A42 B;  3G3Y A;  4FVA A;  2JC5 A;  3G6S A;  2IMQ X;  3NGN A;  4FPV A;  3G91 A;  3TEB A;  4B5M A;  4GEW A;  2UYR X;  5DFH A;  2DNJ A;  4L1Z A;  2JC4 A;  1ZWX A;  2DDS A;  2DDT A;  3G38 A;  1I9Z A;  1DEW A;  1HD7 A;  4K6L F;  1BIX A;  3CJC D;  3G8V A;  1AKO A;  3GA6 A;  4PUQ A;  3DNI A;  3U8U A;  4F1H A;  5DV2 A;  4B5F A;  5CFE A;  2VOA A;  3G0R A;  3I48 A;  5DFF A;  5INM A;  1ATN D;  4CMN A;  1I9Y A;  4B5G A;  1NTF A;  4F1H B;  4L1Y A;  3NGQ A;  3N9V A;  3G2C A;  3W3D B;  1WDU A;  4B5H A;  4GZ2 A;  2A3Z B;  1DE8 A;  5J3P A;  3I41 A;  5A7I A;  2O3C A;  3MTC A;  3L1W A;  4L21 A;  1Y21 A;  3G2D A;  4B5I A;  2ISI A;  5INK A;  4F1R A;  5EWT A;  4QH9 A;  4GZ1 A;  3G0A A;  5J42 A;  3G3C A;  5A7J A;  2A40 B;  3NGO A;  2DDR A;  2F1N A;  3G1K A;  3I5V A;  4LND A;  5INL A;  5J8N A;  5INN A;  5DV4 A;  4RUW A;  4GYZ A;  4F1I A;  5INP A;  1E9N A;  1SI6 X;  3I46 A;  4B5J A;  4QHD A;  5DFI A;  2O3H A;  3W2Y A;  4QHE A;  5HT2 A;  3MPR A;  2J63 A;  5DFJ A;  3K55 A;  4L20 A;  3NR8 A;  5DG0 A;  3FZI A;  5J3Z A;  1SR4 B;  2V0R A;  4IEM A;  4JG3 A;  3WCX A;  1DE9 A;  1DNK A;  4A9C A;  5INQ A;  2EI9 A;  3G00 A;  4GZ0 A;  4C1R A;  3W2X A;  2XSW A;  5INO A;  2D1K B; 
#chains in the Genus database with same CATH topology
 4AWN A;  1YJH A;  2F2F B;  4CML A;  2V0S A;  5J3S A;  2A41 B;  5CFG A;  1VYB A;  3G4T A;  2A42 B;  3G3Y A;  4FVA A;  2JC5 A;  3G6S A;  2IMQ X;  3NGN A;  4FPV A;  3G91 A;  3TEB A;  4B5M A;  4GEW A;  2UYR X;  5DFH A;  2DNJ A;  4L1Z A;  2JC4 A;  1ZWX A;  2DDS A;  2DDT A;  3G38 A;  1I9Z A;  1DEW A;  1HD7 A;  4K6L F;  1BIX A;  3CJC D;  3G8V A;  1AKO A;  3GA6 A;  4PUQ A;  3DNI A;  3U8U A;  4F1H A;  5DV2 A;  4B5F A;  5CFE A;  2VOA A;  3G0R A;  3I48 A;  5DFF A;  5INM A;  1ATN D;  4CMN A;  1I9Y A;  4B5G A;  1NTF A;  4F1H B;  4L1Y A;  3NGQ A;  3N9V A;  3G2C A;  3W3D B;  1WDU A;  4B5H A;  4GZ2 A;  2A3Z B;  1DE8 A;  5J3P A;  3I41 A;  5A7I A;  2O3C A;  3MTC A;  3L1W A;  4L21 A;  1Y21 A;  3G2D A;  4B5I A;  2ISI A;  5INK A;  4F1R A;  5EWT A;  4QH9 A;  4GZ1 A;  3G0A A;  5J42 A;  3G3C A;  5A7J A;  2A40 B;  3NGO A;  2DDR A;  2F1N A;  3G1K A;  3I5V A;  4LND A;  5INL A;  5J8N A;  5INN A;  5DV4 A;  4RUW A;  4GYZ A;  4F1I A;  5INP A;  1E9N A;  1SI6 X;  3I46 A;  4B5J A;  4QHD A;  5DFI A;  2O3H A;  3W2Y A;  4QHE A;  5HT2 A;  3MPR A;  2J63 A;  5DFJ A;  3K55 A;  4L20 A;  3NR8 A;  5DG0 A;  3FZI A;  5J3Z A;  1SR4 B;  2V0R A;  4IEM A;  4JG3 A;  3WCX A;  1DE9 A;  1DNK A;  4A9C A;  5INQ A;  2EI9 A;  3G00 A;  4GZ0 A;  4C1R A;  3W2X A;  2XSW A;  5INO A;  2D1K B; 
#chains in the Genus database with same CATH homology
 4AWN A;  1YJH A;  2F2F B;  4CML A;  2V0S A;  5J3S A;  2A41 B;  5CFG A;  1VYB A;  3G4T A;  2A42 B;  3G3Y A;  4FVA A;  2JC5 A;  3G6S A;  2IMQ X;  3NGN A;  4FPV A;  3G91 A;  3TEB A;  4B5M A;  4GEW A;  2UYR X;  5DFH A;  2DNJ A;  4L1Z A;  2JC4 A;  1ZWX A;  2DDS A;  2DDT A;  3G38 A;  1I9Z A;  1DEW A;  1HD7 A;  4K6L F;  1BIX A;  3CJC D;  3G8V A;  1AKO A;  3GA6 A;  4PUQ A;  3DNI A;  3U8U A;  4F1H A;  5DV2 A;  4B5F A;  5CFE A;  2VOA A;  3G0R A;  3I48 A;  5DFF A;  5INM A;  1ATN D;  4CMN A;  1I9Y A;  4B5G A;  1NTF A;  4F1H B;  4L1Y A;  3NGQ A;  3N9V A;  3G2C A;  3W3D B;  1WDU A;  4B5H A;  4GZ2 A;  2A3Z B;  1DE8 A;  5J3P A;  3I41 A;  5A7I A;  2O3C A;  3MTC A;  3L1W A;  4L21 A;  1Y21 A;  3G2D A;  4B5I A;  2ISI A;  5INK A;  4F1R A;  5EWT A;  4QH9 A;  4GZ1 A;  3G0A A;  5J42 A;  3G3C A;  5A7J A;  2A40 B;  3NGO A;  2DDR A;  2F1N A;  3G1K A;  3I5V A;  4LND A;  5INL A;  5J8N A;  5INN A;  5DV4 A;  4RUW A;  4GYZ A;  4F1I A;  5INP A;  1E9N A;  1SI6 X;  3I46 A;  4B5J A;  4QHD A;  5DFI A;  2O3H A;  3W2Y A;  4QHE A;  5HT2 A;  3MPR A;  2J63 A;  5DFJ A;  3K55 A;  4L20 A;  3NR8 A;  5DG0 A;  3FZI A;  5J3Z A;  1SR4 B;  2V0R A;  4IEM A;  4JG3 A;  3WCX A;  1DE9 A;  1DNK A;  4A9C A;  5INQ A;  2EI9 A;  3G00 A;  4GZ0 A;  4C1R A;  3W2X A;  2XSW A;  5INO A;  2D1K B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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