3BOKA

Structure of the c. botulinum neurotoxin serotype a apo-enzyme
Total Genus 148
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
148
sequence length
423
structure length
416
Chain Sequence
MQFVNKQFNYKDPVNGVDIAYIKIPQMQPVKAFKIHNKIWVIPERDTFTNPEEGDLNPPQVPVSYYDSTYLSTDNEKDNYLKGVTKLFERIYSTDLGRMLLTSIVRGIPFWGGSTIDTELKVIDTNCINVIQPDGSYRSEELNLVIIGPSADIIQFECKSFGHEVLNLTRNGYGSTQYIRFSPDFTFGFEESLEVDTNPLLGAGKFATDPAVTLAHELIHAGHRLYGIAINPNRVFKVNTNAYYEMSGLEVSFEELRTFGGHDAKFIDSLQENEFRLYYYNKFKDIASTLNKAKSIVGTTASLQYMKNVFKEKYLLSEDTSGKFSVDKLKFDKLYKMLTEIYTEDNFVKFFKVLNRKTYLNFDKAVFKINIVPKVNYTIYDGFNLRNTNLAANFNGQNTEINNMNFTKLKNFTGLF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Catalytic features of the botulinum neurotoxin A light chain revealed by high resolution structure of an inhibitory peptide complex.
pubmed doi rcsb
molecule keywords Neurotoxin A
molecule tags Toxin
source organism Clostridium botulinum
total genus 148
structure length 416
sequence length 423
ec nomenclature ec 3.4.24.69: Bontoxilysin.
pdb deposition date 2007-12-17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1240.10 Alpha Beta Alpha-Beta Complex Zincin-like Metalloproteases ("zincins"), catalytic domain like 3bokA00
3V0BA 1G9CA 3QJ0A 3ZUQA 1F31A 3DDBA 3BONA 3DS9A 3ZUSA 2IMBA 2ISHA 1T3CA 1S0FA 1EPWA 2ISGA 1YVGA 1G9BA 1S0DA 5BQMA 4KS6A 3QW6A 2IMCA 1G9DA 1I1EA 3D3XA 1E1HA 2W2DA 4ZJXA 3FFZA 2NZ9A 1ZKXA 4ZKTB 2G7PA 3C89A 4KTXA 2NP0A 3V0AB 2A8AA 1ZKWA 1ZB7A 3C88A 3K3QB 3BTAA 3QW5A 3FIIA 2IMAA 2ILPA 1T3AA 3QIYA 1G9AA 2ISEA 3QIZA 4EL4A 1Z7HA 1ZL6A 1S0GA 3QW8A 2G7KA 3VUOA 1XTFA 1ZN3A 2G7QA 2QN0A 2ETFA 2FPQA 4EJ5A 3DSEA 2XHLA 2NYYA 3FIEA 1ZL5A 3V0BB 1F82A 3BOOA 3DEBA 3V0AA 3BWIA 1S0CA 3C8AA 3NF3A 4HEVA 2A97A 3QW7A 3ZURA 4ELCA 1S0EA 3C8BA 2G7NA 5BQNA 3QIXA 1XTGA 4J1LA 4KUFA 1S0BA 3DDAA 3BOKA
chains in the Genus database with same CATH superfamily
3V0BA 1G9CA 3QJ0A 4IL3A 3ZUQA 1F31A 3DDBA 3BONA 3DS9A 3ZUSA 2IMBA 2ISHA 1T3CA 1S0FA 1EPWA 2ISGA 1YVGA 1G9BA 1S0DA 5BQMA 4QHFA 4KS6A 3QW6A 2IMCA 1G9DA 1I1EA 3D3XA 1E1HA 2W2DA 4ZJXA 3FFZA 2NZ9A 1ZKXA 4ZKTB 2G7PA 3C89A 4KTXA 2NP0A 3V0AB 2A8AA 1ZKWA 4JIUA 2YPTA 1ZB7A 3C88A 3K3QB 3BTAA 3QW5A 3FIIA 3E11A 2IMAA 2ILPA 4AW6A 1T3AA 3QIYA 1G9AA 2ISEA 3QIZA 4EL4A 1Z7HA 3CQBA 1ZL6A 1S0GA 3QW8A 2G7KA 3VUOA 1XTFA 1ZN3A 2G7QA 2QN0A 2ETFA 2FPQA 4EJ5A 3DSEA 2XHLA 2NYYA 3FIEA 1ZL5A 3V0BB 1F82A 3BOOA 3DEBA 3V0AA 3BWIA 1S0CA 3C8AA 3NF3A 2EJQA 4HEVA 2A97A 3QW7A 3ZURA 4ELCA 1S0EA 3C8BA 2G7NA 5BQNA 3QIXA 1XTGA 4J1LA 4KUFA 1S0BA 3DDAA 3BOKA 4JIXA
chains in the Genus database with same CATH topology
3V0BA 1G9CA 3QJ0A 3ZUQA 1F31A 3DDBA 3BONA 3DS9A 3ZUSA 2IMBA 2ISHA 1T3CA 1S0FA 1EPWA 2ISGA 1YVGA 1G9BA 1S0DA 5BQMA 4KS6A 3QW6A 2IMCA 1G9DA 1I1EA 3D3XA 1E1HA 2W2DA 4ZJXA 3FFZA 2NZ9A 1ZKXA 4ZKTB 2G7PA 3C89A 4KTXA 2NP0A 3V0AB 2A8AA 1ZKWA 1ZB7A 3C88A 3K3QB 3BTAA 3QW5A 3FIIA 2IMAA 2ILPA 1T3AA 3QIYA 1G9AA 2ISEA 3QIZA 4EL4A 1Z7HA 1ZL6A 1S0GA 3QW8A 2G7KA 3VUOA 1XTFA 1ZN3A 2G7QA 2QN0A 2ETFA 2FPQA 4EJ5A 3DSEA 2XHLA 2NYYA 3FIEA 1ZL5A 3V0BB 1F82A 3BOOA 3DEBA 3V0AA 3BWIA 1S0CA 3C8AA 3NF3A 4HEVA 2A97A 3QW7A 3ZURA 4ELCA 1S0EA 3C8BA 2G7NA 5BQNA 3QIXA 1XTGA 4J1LA 4KUFA 1S0BA 3DDAA 3BOKA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3V0B A;  1G9C A;  3QJ0 A;  3ZUQ A;  1F31 A;  3DDB A;  3BON A;  3DS9 A;  3ZUS A;  2IMB A;  2ISH A;  1T3C A;  1S0F A;  1EPW A;  2ISG A;  1YVG A;  1G9B A;  1S0D A;  5BQM A;  4KS6 A;  3QW6 A;  2IMC A;  1G9D A;  1I1E A;  3D3X A;  1E1H A;  2W2D A;  4ZJX A;  3FFZ A;  2NZ9 A;  1ZKX A;  4ZKT B;  2G7P A;  3C89 A;  4KTX A;  2NP0 A;  3V0A B;  2A8A A;  1ZKW A;  1ZB7 A;  3C88 A;  3K3Q B;  3BTA A;  3QW5 A;  3FII A;  2IMA A;  2ILP A;  1T3A A;  3QIY A;  1G9A A;  2ISE A;  3QIZ A;  4EL4 A;  1Z7H A;  1ZL6 A;  1S0G A;  3QW8 A;  2G7K A;  3VUO A;  1XTF A;  1ZN3 A;  2G7Q A;  2QN0 A;  2ETF A;  2FPQ A;  4EJ5 A;  3DSE A;  2XHL A;  2NYY A;  3FIE A;  1ZL5 A;  3V0B B;  1F82 A;  3BOO A;  3DEB A;  3V0A A;  3BWI A;  1S0C A;  3C8A A;  3NF3 A;  4HEV A;  2A97 A;  3QW7 A;  3ZUR A;  4ELC A;  1S0E A;  3C8B A;  2G7N A;  5BQN A;  3QIX A;  1XTG A;  4J1L A;  4KUF A;  1S0B A;  3DDA A;  3BOK A; 
#chains in the Genus database with same CATH topology
 3V0B A;  1G9C A;  3QJ0 A;  4IL3 A;  3ZUQ A;  1F31 A;  3DDB A;  3BON A;  3DS9 A;  3ZUS A;  2IMB A;  2ISH A;  1T3C A;  1S0F A;  1EPW A;  2ISG A;  1YVG A;  1G9B A;  1S0D A;  5BQM A;  4QHF A;  4KS6 A;  3QW6 A;  2IMC A;  1G9D A;  1I1E A;  3D3X A;  1E1H A;  2W2D A;  4ZJX A;  3FFZ A;  2NZ9 A;  1ZKX A;  4ZKT B;  2G7P A;  3C89 A;  4KTX A;  2NP0 A;  3V0A B;  2A8A A;  1ZKW A;  4JIU A;  2YPT A;  1ZB7 A;  3C88 A;  3K3Q B;  3BTA A;  3QW5 A;  3FII A;  3E11 A;  2IMA A;  2ILP A;  4AW6 A;  1T3A A;  3QIY A;  1G9A A;  2ISE A;  3QIZ A;  4EL4 A;  1Z7H A;  3CQB A;  1ZL6 A;  1S0G A;  3QW8 A;  2G7K A;  3VUO A;  1XTF A;  1ZN3 A;  2G7Q A;  2QN0 A;  2ETF A;  2FPQ A;  4EJ5 A;  3DSE A;  2XHL A;  2NYY A;  3FIE A;  1ZL5 A;  3V0B B;  1F82 A;  3BOO A;  3DEB A;  3V0A A;  3BWI A;  1S0C A;  3C8A A;  3NF3 A;  2EJQ A;  4HEV A;  2A97 A;  3QW7 A;  3ZUR A;  4ELC A;  1S0E A;  3C8B A;  2G7N A;  5BQN A;  3QIX A;  1XTG A;  4J1L A;  4KUF A;  1S0B A;  3DDA A;  3BOK A;  4JIX A; 
#chains in the Genus database with same CATH homology
 3V0B A;  1G9C A;  3QJ0 A;  3ZUQ A;  1F31 A;  3DDB A;  3BON A;  3DS9 A;  3ZUS A;  2IMB A;  2ISH A;  1T3C A;  1S0F A;  1EPW A;  2ISG A;  1YVG A;  1G9B A;  1S0D A;  5BQM A;  4KS6 A;  3QW6 A;  2IMC A;  1G9D A;  1I1E A;  3D3X A;  1E1H A;  2W2D A;  4ZJX A;  3FFZ A;  2NZ9 A;  1ZKX A;  4ZKT B;  2G7P A;  3C89 A;  4KTX A;  2NP0 A;  3V0A B;  2A8A A;  1ZKW A;  1ZB7 A;  3C88 A;  3K3Q B;  3BTA A;  3QW5 A;  3FII A;  2IMA A;  2ILP A;  1T3A A;  3QIY A;  1G9A A;  2ISE A;  3QIZ A;  4EL4 A;  1Z7H A;  1ZL6 A;  1S0G A;  3QW8 A;  2G7K A;  3VUO A;  1XTF A;  1ZN3 A;  2G7Q A;  2QN0 A;  2ETF A;  2FPQ A;  4EJ5 A;  3DSE A;  2XHL A;  2NYY A;  3FIE A;  1ZL5 A;  3V0B B;  1F82 A;  3BOO A;  3DEB A;  3V0A A;  3BWI A;  1S0C A;  3C8A A;  3NF3 A;  4HEV A;  2A97 A;  3QW7 A;  3ZUR A;  4ELC A;  1S0E A;  3C8B A;  2G7N A;  5BQN A;  3QIX A;  1XTG A;  4J1L A;  4KUF A;  1S0B A;  3DDA A;  3BOK A;
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...
How to cite