3DEBA

Crystal structure of apo form (zinc removed) of the botulinum neurotoxin type c light chain
Total Genus 143
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
143
sequence length
432
structure length
432
Chain Sequence
SHMPITINNFNYSDPVDNKNILYLDTHLNTLANEPEKAFRITGNIWVIPDRFSRNSNPNLNKPPRVTSPKSGYYDPNYLSTDSDKDTFLKEIIKLFKRINSREIGEELIYRLSTDIPFPGNNNTPINTFDFDVDFNSVDVKTRQGNNWVKTGSINPSVIITGPRENIIDPETSTFKLTNNTFAAQEGFGALSIISISPRFMLTYSNATNDVGEGRFSKSEFCMDPILILMHELNHAMHNLYGIAIPNDQTISSVTSNIFYSQYNVKLEYAEIYAFGGPTIDLIPKSARKYFEEKALDYYRSIAKRLNSITTANPSSFNKYIGEYKQKLIRKYRFVVESSGEVTVNRNKFVELYNELTQIFTEFNYAKIYNVQNRKIYLSNVYTPVTANILDDNVYDIQNGFNIPKSNLNVLFMGQNLSRNPALRKVNPENML
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Clostridium botulinum
publication title Crystal Structure of apo form (Zinc removed) of the Botulinum Neurotoxin Type C Light Chain
rcsb
molecule keywords Botulinum neurotoxin C1 light chain
total genus 143
structure length 432
sequence length 432
ec nomenclature ec 3.4.24.69: Bontoxilysin.
pdb deposition date 2008-06-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01742 Peptidase_M27 Clostridial neurotoxin zinc protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1240.10 Alpha Beta Alpha-Beta Complex Zincin-like Metalloproteases ("zincins"), catalytic domain like 3debA00
1ZN3A 4EL4A 3FFZA 1G9DA 2FPQA 1ZB7A 3BOOA 1S0DA 2XHLA 2G7PA 3BONA 5BQNA 1T3AA 2ISGA 3K3QB 2W2DA 3VUOA 2NP0A 1S0EA 2IMBA 3BOKA 1T3CA 2G7QA 1S0FA 1ZL5A 1G9CA 3BWIA 4ZJXA 2NYYA 1S0BA 3DDAA 1F82A 3C8BA 3QW7A 3ZUSA 1XTFA 2A8AA 1ZL6A 4ZKTB 1ZKXA 3QJ0A 4KUFA 4J1LA 1G9BA 2IMCA 1F31A 3DS9A 1G9AA 2A97A 4EJ5A 3DDBA 2ETFA 2NZ9A 3QIYA 3DSEA 3QIZA 4ELCA 5BQMA 3D3XA 2G7KA 3BTAA 1ZKWA 3ZUQA 3C8AA 1EPWA 1Z7HA 3QW5A 3QW8A 3FIIA 2QN0A 3DEBA 3C88A 1E1HA 4KTXA 2IMAA 2ISEA 2G7NA 3V0BB 1S0GA 3FIEA 4HEVA 1I1EA 3V0AA 3C89A 1YVGA 3ZURA 3V0AB 3QIXA 4KS6A 3NF3A 2ILPA 2ISHA 1S0CA 3V0BA 3QW6A 1XTGA
chains in the Genus database with same CATH superfamily
1ZN3A 4EL4A 2YPTA 3FFZA 1G9DA 2FPQA 1ZB7A 3BOOA 1S0DA 2EJQA 2G7PA 2XHLA 3BONA 5BQNA 1T3AA 2ISGA 3K3QB 2W2DA 3VUOA 2NP0A 1S0EA 2IMBA 3BOKA 1T3CA 2G7QA 1S0FA 1ZL5A 4JIXA 1G9CA 3BWIA 4ZJXA 2NYYA 1S0BA 3DDAA 1F82A 3C8BA 3QW7A 3ZUSA 1XTFA 2A8AA 1ZL6A 4ZKTB 1ZKXA 3QJ0A 4KUFA 4J1LA 1G9BA 2IMCA 1F31A 3DS9A 1G9AA 4JIUA 2A97A 4EJ5A 3DDBA 2ETFA 2NZ9A 3QIYA 3DSEA 3QIZA 4ELCA 5BQMA 3D3XA 2G7KA 3BTAA 1ZKWA 3ZUQA 3C8AA 1EPWA 1Z7HA 3QW5A 3QW8A 3E11A 3FIIA 2QN0A 3CQBA 3DEBA 3C88A 1E1HA 4QHFA 4KTXA 2IMAA 2ISEA 2G7NA 3V0BB 1S0GA 3FIEA 4HEVA 1I1EA 3V0AA 3C89A 1YVGA 3ZURA 4IL3A 3V0AB 4AW6A 3QIXA 4KS6A 3NF3A 2ILPA 2ISHA 1S0CA 3V0BA 3QW6A 1XTGA
chains in the Genus database with same CATH topology
1ZN3A 4EL4A 3FFZA 1G9DA 2FPQA 1ZB7A 3BOOA 1S0DA 2XHLA 2G7PA 3BONA 5BQNA 1T3AA 2ISGA 3K3QB 2W2DA 3VUOA 2NP0A 1S0EA 2IMBA 3BOKA 1T3CA 2G7QA 1S0FA 1ZL5A 1G9CA 3BWIA 4ZJXA 2NYYA 1S0BA 3DDAA 1F82A 3C8BA 3QW7A 3ZUSA 1XTFA 2A8AA 1ZL6A 4ZKTB 1ZKXA 3QJ0A 4KUFA 4J1LA 1G9BA 2IMCA 1F31A 3DS9A 1G9AA 2A97A 4EJ5A 3DDBA 2ETFA 2NZ9A 3QIYA 3DSEA 3QIZA 4ELCA 5BQMA 3D3XA 2G7KA 3BTAA 1ZKWA 3ZUQA 3C8AA 1EPWA 1Z7HA 3QW5A 3QW8A 3FIIA 2QN0A 3DEBA 3C88A 1E1HA 4KTXA 2IMAA 2ISEA 2G7NA 3V0BB 1S0GA 3FIEA 4HEVA 1I1EA 3V0AA 3C89A 1YVGA 3ZURA 3V0AB 3QIXA 4KS6A 3NF3A 2ILPA 2ISHA 1S0CA 3V0BA 3QW6A 1XTGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZN3 A;  4EL4 A;  3FFZ A;  1G9D A;  2FPQ A;  1ZB7 A;  3BOO A;  1S0D A;  2XHL A;  2G7P A;  3BON A;  5BQN A;  1T3A A;  2ISG A;  3K3Q B;  2W2D A;  3VUO A;  2NP0 A;  1S0E A;  2IMB A;  3BOK A;  1T3C A;  2G7Q A;  1S0F A;  1ZL5 A;  1G9C A;  3BWI A;  4ZJX A;  2NYY A;  1S0B A;  3DDA A;  1F82 A;  3C8B A;  3QW7 A;  3ZUS A;  1XTF A;  2A8A A;  1ZL6 A;  4ZKT B;  1ZKX A;  3QJ0 A;  4KUF A;  4J1L A;  1G9B A;  2IMC A;  1F31 A;  3DS9 A;  1G9A A;  2A97 A;  4EJ5 A;  3DDB A;  2ETF A;  2NZ9 A;  3QIY A;  3DSE A;  3QIZ A;  4ELC A;  5BQM A;  3D3X A;  2G7K A;  3BTA A;  1ZKW A;  3ZUQ A;  3C8A A;  1EPW A;  1Z7H A;  3QW5 A;  3QW8 A;  3FII A;  2QN0 A;  3DEB A;  3C88 A;  1E1H A;  4KTX A;  2IMA A;  2ISE A;  2G7N A;  3V0B B;  1S0G A;  3FIE A;  4HEV A;  1I1E A;  3V0A A;  3C89 A;  1YVG A;  3ZUR A;  3V0A B;  3QIX A;  4KS6 A;  3NF3 A;  2ILP A;  2ISH A;  1S0C A;  3V0B A;  3QW6 A;  1XTG A; 
#chains in the Genus database with same CATH topology
 1ZN3 A;  4EL4 A;  2YPT A;  3FFZ A;  1G9D A;  2FPQ A;  1ZB7 A;  3BOO A;  1S0D A;  2EJQ A;  2G7P A;  2XHL A;  3BON A;  5BQN A;  1T3A A;  2ISG A;  3K3Q B;  2W2D A;  3VUO A;  2NP0 A;  1S0E A;  2IMB A;  3BOK A;  1T3C A;  2G7Q A;  1S0F A;  1ZL5 A;  4JIX A;  1G9C A;  3BWI A;  4ZJX A;  2NYY A;  1S0B A;  3DDA A;  1F82 A;  3C8B A;  3QW7 A;  3ZUS A;  1XTF A;  2A8A A;  1ZL6 A;  4ZKT B;  1ZKX A;  3QJ0 A;  4KUF A;  4J1L A;  1G9B A;  2IMC A;  1F31 A;  3DS9 A;  1G9A A;  4JIU A;  2A97 A;  4EJ5 A;  3DDB A;  2ETF A;  2NZ9 A;  3QIY A;  3DSE A;  3QIZ A;  4ELC A;  5BQM A;  3D3X A;  2G7K A;  3BTA A;  1ZKW A;  3ZUQ A;  3C8A A;  1EPW A;  1Z7H A;  3QW5 A;  3QW8 A;  3E11 A;  3FII A;  2QN0 A;  3CQB A;  3DEB A;  3C88 A;  1E1H A;  4QHF A;  4KTX A;  2IMA A;  2ISE A;  2G7N A;  3V0B B;  1S0G A;  3FIE A;  4HEV A;  1I1E A;  3V0A A;  3C89 A;  1YVG A;  3ZUR A;  4IL3 A;  3V0A B;  4AW6 A;  3QIX A;  4KS6 A;  3NF3 A;  2ILP A;  2ISH A;  1S0C A;  3V0B A;  3QW6 A;  1XTG A; 
#chains in the Genus database with same CATH homology
 1ZN3 A;  4EL4 A;  3FFZ A;  1G9D A;  2FPQ A;  1ZB7 A;  3BOO A;  1S0D A;  2XHL A;  2G7P A;  3BON A;  5BQN A;  1T3A A;  2ISG A;  3K3Q B;  2W2D A;  3VUO A;  2NP0 A;  1S0E A;  2IMB A;  3BOK A;  1T3C A;  2G7Q A;  1S0F A;  1ZL5 A;  1G9C A;  3BWI A;  4ZJX A;  2NYY A;  1S0B A;  3DDA A;  1F82 A;  3C8B A;  3QW7 A;  3ZUS A;  1XTF A;  2A8A A;  1ZL6 A;  4ZKT B;  1ZKX A;  3QJ0 A;  4KUF A;  4J1L A;  1G9B A;  2IMC A;  1F31 A;  3DS9 A;  1G9A A;  2A97 A;  4EJ5 A;  3DDB A;  2ETF A;  2NZ9 A;  3QIY A;  3DSE A;  3QIZ A;  4ELC A;  5BQM A;  3D3X A;  2G7K A;  3BTA A;  1ZKW A;  3ZUQ A;  3C8A A;  1EPW A;  1Z7H A;  3QW5 A;  3QW8 A;  3FII A;  2QN0 A;  3DEB A;  3C88 A;  1E1H A;  4KTX A;  2IMA A;  2ISE A;  2G7N A;  3V0B B;  1S0G A;  3FIE A;  4HEV A;  1I1E A;  3V0A A;  3C89 A;  1YVG A;  3ZUR A;  3V0A B;  3QIX A;  4KS6 A;  3NF3 A;  2ILP A;  2ISH A;  1S0C A;  3V0B A;  3QW6 A;  1XTG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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