3FIIA

Crystal structure of clostridium botulinum neurotoxin serotype f catalytic domain with an inhibitor (inh2)
Total Genus 136
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
136
sequence length
411
structure length
403
Chain Sequence
PVVINSFNYNDPVNDDTILYMQIPYEEKSKKYYKAFEIMRNVWIIPERNTIGTDPSDFDPPASLENGSSAYYDPNYLTTDAEKDRYLKTTIKLFKRINSNPAGEVLLQEISYAKPYLGNEHTPINEFHPVTRTTSVNIKSSTNVKSSIILNLLVLGAGPDIFENSSYPVRKLMDSGGVYDPSNDGFGSINIVTFSPEYEYTFNDTESFIADPAISLAHELIHALHGLYGARGVTYKETIKVKQAPLMIAEKPIRLEEFLTFGGQDLNIITSAMKEKIYNNLLANYEKIATRLSRVNSAPPEYDINEYKDYFQWKYGLDKNADGSYTVNENKFNEIYKKLYSFTEIDLANKFKVKCRNTYFIKYGFLKVPNLLDDDIYTVSEGFNIGNLAVNNRGQNIKLNPKI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Mode of VAMP substrate recognition and inhibition of Clostridium botulinum neurotoxin F.
pubmed doi rcsb
molecule tags Hydrolase, toxin/protein transport
source organism Clostridium botulinum
molecule keywords BOTULINUM NEUROTOXIN TYPE F
total genus 136
structure length 403
sequence length 411
ec nomenclature ec 3.4.24.69: Bontoxilysin.
pdb deposition date 2008-12-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01742 Peptidase_M27 Clostridial neurotoxin zinc protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1240.10 Alpha Beta Alpha-Beta Complex Zincin-like Metalloproteases ("zincins"), catalytic domain like 3fiiA00
3DDBA 2NYYA 1S0BA 2ETFA 1XTFA 1I1EA 2IMCA 2G7NA 1S0EA 3QIYA 3QW6A 1ZKWA 2IMBA 2G7KA 3QW5A 3BWIA 4EL4A 2XHLA 2W2DA 2NP0A 3FIIA 1XTGA 3V0AB 4KUFA 3ZUQA 2NZ9A 1YVGA 2FPQA 1G9CA 3C89A 3QW8A 4ZJXA 1S0DA 3FFZA 2G7PA 3DS9A 1S0CA 2ISHA 3FIEA 1S0GA 1G9AA 5BQNA 3V0BB 2ISEA 3D3XA 4HEVA 1E1HA 4KTXA 3BTAA 3K3QB 3C8AA 1T3CA 2ISGA 1EPWA 4J1LA 2G7QA 2QN0A 3QIXA 3QJ0A 1ZB7A 1F31A 2ILPA 3VUOA 3QIZA 3C8BA 3ZUSA 3DSEA 2A97A 3DDAA 1ZL5A 3V0AA 3C88A 4ZKTB 4ELCA 2IMAA 3BONA 1S0FA 4EJ5A 3NF3A 3BOOA 1G9DA 1T3AA 3DEBA 1Z7HA 1F82A 3ZURA 5BQMA 4KS6A 3QW7A 3V0BA 1ZKXA 1G9BA 2A8AA 3BOKA 1ZL6A 1ZN3A
chains in the Genus database with same CATH superfamily
3DDBA 2NYYA 1S0BA 2ETFA 1XTFA 1I1EA 2IMCA 2G7NA 1S0EA 3QIYA 3QW6A 1ZKWA 2IMBA 2G7KA 3QW5A 3BWIA 4EL4A 2XHLA 2W2DA 2NP0A 3FIIA 1XTGA 3V0AB 4KUFA 3ZUQA 2YPTA 2NZ9A 1YVGA 2FPQA 1G9CA 3C89A 3QW8A 4ZJXA 4AW6A 1S0DA 3FFZA 2G7PA 3DS9A 1S0CA 2ISHA 3FIEA 1S0GA 4QHFA 1G9AA 4IL3A 5BQNA 3V0BB 2ISEA 3D3XA 4JIXA 4HEVA 1E1HA 4KTXA 3BTAA 3K3QB 3C8AA 4JIUA 2EJQA 3CQBA 1T3CA 2ISGA 1EPWA 4J1LA 2G7QA 2QN0A 3QIXA 3QJ0A 1ZB7A 1F31A 2ILPA 3VUOA 3QIZA 3C8BA 3ZUSA 3DSEA 2A97A 3DDAA 1ZL5A 3V0AA 3C88A 4ZKTB 4ELCA 2IMAA 3BONA 1S0FA 4EJ5A 3NF3A 3BOOA 1G9DA 1T3AA 3DEBA 1Z7HA 1F82A 3ZURA 3E11A 5BQMA 4KS6A 3QW7A 3V0BA 1ZKXA 1G9BA 2A8AA 3BOKA 1ZL6A 1ZN3A
chains in the Genus database with same CATH topology
3DDBA 2NYYA 1S0BA 2ETFA 1XTFA 1I1EA 2IMCA 2G7NA 1S0EA 3QIYA 3QW6A 1ZKWA 2IMBA 2G7KA 3QW5A 3BWIA 4EL4A 2XHLA 2W2DA 2NP0A 3FIIA 1XTGA 3V0AB 4KUFA 3ZUQA 2NZ9A 1YVGA 2FPQA 1G9CA 3C89A 3QW8A 4ZJXA 1S0DA 3FFZA 2G7PA 3DS9A 1S0CA 2ISHA 3FIEA 1S0GA 1G9AA 5BQNA 3V0BB 2ISEA 3D3XA 4HEVA 1E1HA 4KTXA 3BTAA 3K3QB 3C8AA 1T3CA 2ISGA 1EPWA 4J1LA 2G7QA 2QN0A 3QIXA 3QJ0A 1ZB7A 1F31A 2ILPA 3VUOA 3QIZA 3C8BA 3ZUSA 3DSEA 2A97A 3DDAA 1ZL5A 3V0AA 3C88A 4ZKTB 4ELCA 2IMAA 3BONA 1S0FA 4EJ5A 3NF3A 3BOOA 1G9DA 1T3AA 3DEBA 1Z7HA 1F82A 3ZURA 5BQMA 4KS6A 3QW7A 3V0BA 1ZKXA 1G9BA 2A8AA 3BOKA 1ZL6A 1ZN3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DDB A;  2NYY A;  1S0B A;  2ETF A;  1XTF A;  1I1E A;  2IMC A;  2G7N A;  1S0E A;  3QIY A;  3QW6 A;  1ZKW A;  2IMB A;  2G7K A;  3QW5 A;  3BWI A;  4EL4 A;  2XHL A;  2W2D A;  2NP0 A;  3FII A;  1XTG A;  3V0A B;  4KUF A;  3ZUQ A;  2NZ9 A;  1YVG A;  2FPQ A;  1G9C A;  3C89 A;  3QW8 A;  4ZJX A;  1S0D A;  3FFZ A;  2G7P A;  3DS9 A;  1S0C A;  2ISH A;  3FIE A;  1S0G A;  1G9A A;  5BQN A;  3V0B B;  2ISE A;  3D3X A;  4HEV A;  1E1H A;  4KTX A;  3BTA A;  3K3Q B;  3C8A A;  1T3C A;  2ISG A;  1EPW A;  4J1L A;  2G7Q A;  2QN0 A;  3QIX A;  3QJ0 A;  1ZB7 A;  1F31 A;  2ILP A;  3VUO A;  3QIZ A;  3C8B A;  3ZUS A;  3DSE A;  2A97 A;  3DDA A;  1ZL5 A;  3V0A A;  3C88 A;  4ZKT B;  4ELC A;  2IMA A;  3BON A;  1S0F A;  4EJ5 A;  3NF3 A;  3BOO A;  1G9D A;  1T3A A;  3DEB A;  1Z7H A;  1F82 A;  3ZUR A;  5BQM A;  4KS6 A;  3QW7 A;  3V0B A;  1ZKX A;  1G9B A;  2A8A A;  3BOK A;  1ZL6 A;  1ZN3 A; 
#chains in the Genus database with same CATH topology
 3DDB A;  2NYY A;  1S0B A;  2ETF A;  1XTF A;  1I1E A;  2IMC A;  2G7N A;  1S0E A;  3QIY A;  3QW6 A;  1ZKW A;  2IMB A;  2G7K A;  3QW5 A;  3BWI A;  4EL4 A;  2XHL A;  2W2D A;  2NP0 A;  3FII A;  1XTG A;  3V0A B;  4KUF A;  3ZUQ A;  2YPT A;  2NZ9 A;  1YVG A;  2FPQ A;  1G9C A;  3C89 A;  3QW8 A;  4ZJX A;  4AW6 A;  1S0D A;  3FFZ A;  2G7P A;  3DS9 A;  1S0C A;  2ISH A;  3FIE A;  1S0G A;  4QHF A;  1G9A A;  4IL3 A;  5BQN A;  3V0B B;  2ISE A;  3D3X A;  4JIX A;  4HEV A;  1E1H A;  4KTX A;  3BTA A;  3K3Q B;  3C8A A;  4JIU A;  2EJQ A;  3CQB A;  1T3C A;  2ISG A;  1EPW A;  4J1L A;  2G7Q A;  2QN0 A;  3QIX A;  3QJ0 A;  1ZB7 A;  1F31 A;  2ILP A;  3VUO A;  3QIZ A;  3C8B A;  3ZUS A;  3DSE A;  2A97 A;  3DDA A;  1ZL5 A;  3V0A A;  3C88 A;  4ZKT B;  4ELC A;  2IMA A;  3BON A;  1S0F A;  4EJ5 A;  3NF3 A;  3BOO A;  1G9D A;  1T3A A;  3DEB A;  1Z7H A;  1F82 A;  3ZUR A;  3E11 A;  5BQM A;  4KS6 A;  3QW7 A;  3V0B A;  1ZKX A;  1G9B A;  2A8A A;  3BOK A;  1ZL6 A;  1ZN3 A; 
#chains in the Genus database with same CATH homology
 3DDB A;  2NYY A;  1S0B A;  2ETF A;  1XTF A;  1I1E A;  2IMC A;  2G7N A;  1S0E A;  3QIY A;  3QW6 A;  1ZKW A;  2IMB A;  2G7K A;  3QW5 A;  3BWI A;  4EL4 A;  2XHL A;  2W2D A;  2NP0 A;  3FII A;  1XTG A;  3V0A B;  4KUF A;  3ZUQ A;  2NZ9 A;  1YVG A;  2FPQ A;  1G9C A;  3C89 A;  3QW8 A;  4ZJX A;  1S0D A;  3FFZ A;  2G7P A;  3DS9 A;  1S0C A;  2ISH A;  3FIE A;  1S0G A;  1G9A A;  5BQN A;  3V0B B;  2ISE A;  3D3X A;  4HEV A;  1E1H A;  4KTX A;  3BTA A;  3K3Q B;  3C8A A;  1T3C A;  2ISG A;  1EPW A;  4J1L A;  2G7Q A;  2QN0 A;  3QIX A;  3QJ0 A;  1ZB7 A;  1F31 A;  2ILP A;  3VUO A;  3QIZ A;  3C8B A;  3ZUS A;  3DSE A;  2A97 A;  3DDA A;  1ZL5 A;  3V0A A;  3C88 A;  4ZKT B;  4ELC A;  2IMA A;  3BON A;  1S0F A;  4EJ5 A;  3NF3 A;  3BOO A;  1G9D A;  1T3A A;  3DEB A;  1Z7H A;  1F82 A;  3ZUR A;  5BQM A;  4KS6 A;  3QW7 A;  3V0B A;  1ZKX A;  1G9B A;  2A8A A;  3BOK A;  1ZL6 A;  1ZN3 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...