4B5GA

Substrate bound neisseria ap endonuclease in absence of metal ions (crystal form 2)
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
259
structure length
259
Chain Sequence
MLKIISANVNGIRSAYKKGFYEYIAASGADIVCVQELKAQEADLSADMKNPHGMHGHWHCAEKRGYSGVAVYSKRKPDNVQIGMGIEEFDREGRFVRCDFGRLSVISLYLPSGSSAEERQQVKYRFLDAFYPMLEAMKNEGRDIVVCGDWNIAHQNIDLKNWKGNQKNSGFLPEEREWIGKVIHKLGWTDMWRTLYPDVPGYTWWSNRGQAYAKDVGWRIDYQMVTPELAAKAVSAHVYKDEKFSDHAPLVVEYDYAAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Neisseria meningitidis
molecule keywords EXODEOXYRIBONUCLEASE
total genus 82
structure length 259
sequence length 259
chains with identical sequence B, C
ec nomenclature ec 3.1.11.2: Exodeoxyribonuclease III.
pdb deposition date 2012-08-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 4b5gA00
5DFHA 3NGNA 2J63A 3G38A 5EWTA 4A9CA 5A7IA 1E9NA 2DDTA 3N9VA 4K6LF 4LNDA 1ATND 5A7JA 5INOA 1SI6X 3MTCA 4F1RA 5J42A 5DFFA 1HD7A 4GZ0A 2XSWA 3G2DA 2A41B 5J3PA 3U8UA 5INNA 4B5JA 2O3CA 3G0AA 4FVAA 1YJHA 3G6SA 3G8VA 3W2YA 2IMQX 4F1IA 4GYZA 3G00A 1DE9A 1NTFA 5DFIA 4IEMA 2V0SA 3I41A 5J3SA 2F2FB 4F1HB 1WDUA 3G1KA 1DE8A 4PUQA 4GZ2A 5DG0A 4CMLA 4L21A 3TEBA 4B5HA 1I9YA 2A3ZB 5INMA 2ISIA 2DDRA 3G2CA 4GZ1A 3G3YA 4F1HA 5DFJA 4L20A 1VYBA 3NR8A 1Y21A 4QHEA 3FZIA 2DDSA 1I9ZA 5J3ZA 4JG3A 2F1NA 1DNKA 3NGQA 2A42B 4L1ZA 3GA6A 3W3DB 5INPA 2V0RA 4QH9A 2JC5A 4B5GA 4AWNA 2UYRX 4L1YA 5DV4A 4C1RA 3CJCD 3I48A 1ZWXA 4CMNA 4FPVA 3K55A 5INKA 3G91A 3W2XA 4RUWA 2EI9A 4B5FA 3L1WA 5INQA 2O3HA 2A40B 5CFGA 3NGOA 3G4TA 3G3CA 5INLA 1SR4B 5J8NA 5DV2A 3DNIA 4GEWA 5CFEA 1DEWA 3MPRA 4QHDA 2D1KB 2DNJA 3I5VA 5HT2A 1AKOA 4B5MA 2VOAA 1BIXA 4B5IA 3WCXA 3G0RA 2JC4A 3I46A
chains in the Genus database with same CATH superfamily
5DFHA 3NGNA 2J63A 3G38A 5EWTA 4A9CA 5A7IA 1E9NA 2DDTA 3N9VA 4K6LF 4LNDA 1ATND 5A7JA 5INOA 1SI6X 3MTCA 4F1RA 5J42A 5DFFA 1HD7A 4GZ0A 2XSWA 3G2DA 2A41B 5J3PA 3U8UA 5INNA 4B5JA 2O3CA 3G0AA 4FVAA 1YJHA 3G6SA 3G8VA 3W2YA 2IMQX 4F1IA 4GYZA 3G00A 1DE9A 1NTFA 5DFIA 4IEMA 2V0SA 3I41A 5J3SA 2F2FB 4F1HB 1WDUA 3G1KA 1DE8A 4PUQA 4GZ2A 5DG0A 4CMLA 4L21A 3TEBA 4B5HA 1I9YA 2A3ZB 5INMA 2ISIA 2DDRA 3G2CA 4GZ1A 3G3YA 4F1HA 5DFJA 4L20A 1VYBA 3NR8A 1Y21A 4QHEA 3FZIA 2DDSA 1I9ZA 5J3ZA 4JG3A 2F1NA 1DNKA 3NGQA 2A42B 4L1ZA 3GA6A 3W3DB 5INPA 2V0RA 4QH9A 2JC5A 4B5GA 4AWNA 2UYRX 4L1YA 5DV4A 4C1RA 3CJCD 3I48A 1ZWXA 4CMNA 4FPVA 3K55A 5INKA 3G91A 3W2XA 4RUWA 2EI9A 4B5FA 3L1WA 5INQA 2O3HA 2A40B 5CFGA 3NGOA 3G4TA 3G3CA 5INLA 1SR4B 5J8NA 5DV2A 3DNIA 4GEWA 5CFEA 1DEWA 3MPRA 4QHDA 2D1KB 2DNJA 3I5VA 5HT2A 1AKOA 4B5MA 2VOAA 1BIXA 4B5IA 3WCXA 3G0RA 2JC4A 3I46A
chains in the Genus database with same CATH topology
5DFHA 3NGNA 2J63A 3G38A 5EWTA 4A9CA 5A7IA 1E9NA 2DDTA 3N9VA 4K6LF 4LNDA 1ATND 5A7JA 5INOA 1SI6X 3MTCA 4F1RA 5J42A 5DFFA 1HD7A 4GZ0A 2XSWA 3G2DA 2A41B 5J3PA 3U8UA 5INNA 4B5JA 2O3CA 3G0AA 4FVAA 1YJHA 3G6SA 3G8VA 3W2YA 2IMQX 4F1IA 4GYZA 3G00A 1DE9A 1NTFA 5DFIA 4IEMA 2V0SA 3I41A 5J3SA 2F2FB 4F1HB 1WDUA 3G1KA 1DE8A 4PUQA 4GZ2A 5DG0A 4CMLA 4L21A 3TEBA 4B5HA 1I9YA 2A3ZB 5INMA 2ISIA 2DDRA 3G2CA 4GZ1A 3G3YA 4F1HA 5DFJA 4L20A 1VYBA 3NR8A 1Y21A 4QHEA 3FZIA 2DDSA 1I9ZA 5J3ZA 4JG3A 2F1NA 1DNKA 3NGQA 2A42B 4L1ZA 3GA6A 3W3DB 5INPA 2V0RA 4QH9A 2JC5A 4B5GA 4AWNA 2UYRX 4L1YA 5DV4A 4C1RA 3CJCD 3I48A 1ZWXA 4CMNA 4FPVA 3K55A 5INKA 3G91A 3W2XA 4RUWA 2EI9A 4B5FA 3L1WA 5INQA 2O3HA 2A40B 5CFGA 3NGOA 3G4TA 3G3CA 5INLA 1SR4B 5J8NA 5DV2A 3DNIA 4GEWA 5CFEA 1DEWA 3MPRA 4QHDA 2D1KB 2DNJA 3I5VA 5HT2A 1AKOA 4B5MA 2VOAA 1BIXA 4B5IA 3WCXA 3G0RA 2JC4A 3I46A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DFH A;  3NGN A;  2J63 A;  3G38 A;  5EWT A;  4A9C A;  5A7I A;  1E9N A;  2DDT A;  3N9V A;  4K6L F;  4LND A;  1ATN D;  5A7J A;  5INO A;  1SI6 X;  3MTC A;  4F1R A;  5J42 A;  5DFF A;  1HD7 A;  4GZ0 A;  2XSW A;  3G2D A;  2A41 B;  5J3P A;  3U8U A;  5INN A;  4B5J A;  2O3C A;  3G0A A;  4FVA A;  1YJH A;  3G6S A;  3G8V A;  3W2Y A;  2IMQ X;  4F1I A;  4GYZ A;  3G00 A;  1DE9 A;  1NTF A;  5DFI A;  4IEM A;  2V0S A;  3I41 A;  5J3S A;  2F2F B;  4F1H B;  1WDU A;  3G1K A;  1DE8 A;  4PUQ A;  4GZ2 A;  5DG0 A;  4CML A;  4L21 A;  3TEB A;  4B5H A;  1I9Y A;  2A3Z B;  5INM A;  2ISI A;  2DDR A;  3G2C A;  4GZ1 A;  3G3Y A;  4F1H A;  5DFJ A;  4L20 A;  1VYB A;  3NR8 A;  1Y21 A;  4QHE A;  3FZI A;  2DDS A;  1I9Z A;  5J3Z A;  4JG3 A;  2F1N A;  1DNK A;  3NGQ A;  2A42 B;  4L1Z A;  3GA6 A;  3W3D B;  5INP A;  2V0R A;  4QH9 A;  2JC5 A;  4B5G A;  4AWN A;  2UYR X;  4L1Y A;  5DV4 A;  4C1R A;  3CJC D;  3I48 A;  1ZWX A;  4CMN A;  4FPV A;  3K55 A;  5INK A;  3G91 A;  3W2X A;  4RUW A;  2EI9 A;  4B5F A;  3L1W A;  5INQ A;  2O3H A;  2A40 B;  5CFG A;  3NGO A;  3G4T A;  3G3C A;  5INL A;  1SR4 B;  5J8N A;  5DV2 A;  3DNI A;  4GEW A;  5CFE A;  1DEW A;  3MPR A;  4QHD A;  2D1K B;  2DNJ A;  3I5V A;  5HT2 A;  1AKO A;  4B5M A;  2VOA A;  1BIX A;  4B5I A;  3WCX A;  3G0R A;  2JC4 A;  3I46 A; 
#chains in the Genus database with same CATH topology
 5DFH A;  3NGN A;  2J63 A;  3G38 A;  5EWT A;  4A9C A;  5A7I A;  1E9N A;  2DDT A;  3N9V A;  4K6L F;  4LND A;  1ATN D;  5A7J A;  5INO A;  1SI6 X;  3MTC A;  4F1R A;  5J42 A;  5DFF A;  1HD7 A;  4GZ0 A;  2XSW A;  3G2D A;  2A41 B;  5J3P A;  3U8U A;  5INN A;  4B5J A;  2O3C A;  3G0A A;  4FVA A;  1YJH A;  3G6S A;  3G8V A;  3W2Y A;  2IMQ X;  4F1I A;  4GYZ A;  3G00 A;  1DE9 A;  1NTF A;  5DFI A;  4IEM A;  2V0S A;  3I41 A;  5J3S A;  2F2F B;  4F1H B;  1WDU A;  3G1K A;  1DE8 A;  4PUQ A;  4GZ2 A;  5DG0 A;  4CML A;  4L21 A;  3TEB A;  4B5H A;  1I9Y A;  2A3Z B;  5INM A;  2ISI A;  2DDR A;  3G2C A;  4GZ1 A;  3G3Y A;  4F1H A;  5DFJ A;  4L20 A;  1VYB A;  3NR8 A;  1Y21 A;  4QHE A;  3FZI A;  2DDS A;  1I9Z A;  5J3Z A;  4JG3 A;  2F1N A;  1DNK A;  3NGQ A;  2A42 B;  4L1Z A;  3GA6 A;  3W3D B;  5INP A;  2V0R A;  4QH9 A;  2JC5 A;  4B5G A;  4AWN A;  2UYR X;  4L1Y A;  5DV4 A;  4C1R A;  3CJC D;  3I48 A;  1ZWX A;  4CMN A;  4FPV A;  3K55 A;  5INK A;  3G91 A;  3W2X A;  4RUW A;  2EI9 A;  4B5F A;  3L1W A;  5INQ A;  2O3H A;  2A40 B;  5CFG A;  3NGO A;  3G4T A;  3G3C A;  5INL A;  1SR4 B;  5J8N A;  5DV2 A;  3DNI A;  4GEW A;  5CFE A;  1DEW A;  3MPR A;  4QHD A;  2D1K B;  2DNJ A;  3I5V A;  5HT2 A;  1AKO A;  4B5M A;  2VOA A;  1BIX A;  4B5I A;  3WCX A;  3G0R A;  2JC4 A;  3I46 A; 
#chains in the Genus database with same CATH homology
 5DFH A;  3NGN A;  2J63 A;  3G38 A;  5EWT A;  4A9C A;  5A7I A;  1E9N A;  2DDT A;  3N9V A;  4K6L F;  4LND A;  1ATN D;  5A7J A;  5INO A;  1SI6 X;  3MTC A;  4F1R A;  5J42 A;  5DFF A;  1HD7 A;  4GZ0 A;  2XSW A;  3G2D A;  2A41 B;  5J3P A;  3U8U A;  5INN A;  4B5J A;  2O3C A;  3G0A A;  4FVA A;  1YJH A;  3G6S A;  3G8V A;  3W2Y A;  2IMQ X;  4F1I A;  4GYZ A;  3G00 A;  1DE9 A;  1NTF A;  5DFI A;  4IEM A;  2V0S A;  3I41 A;  5J3S A;  2F2F B;  4F1H B;  1WDU A;  3G1K A;  1DE8 A;  4PUQ A;  4GZ2 A;  5DG0 A;  4CML A;  4L21 A;  3TEB A;  4B5H A;  1I9Y A;  2A3Z B;  5INM A;  2ISI A;  2DDR A;  3G2C A;  4GZ1 A;  3G3Y A;  4F1H A;  5DFJ A;  4L20 A;  1VYB A;  3NR8 A;  1Y21 A;  4QHE A;  3FZI A;  2DDS A;  1I9Z A;  5J3Z A;  4JG3 A;  2F1N A;  1DNK A;  3NGQ A;  2A42 B;  4L1Z A;  3GA6 A;  3W3D B;  5INP A;  2V0R A;  4QH9 A;  2JC5 A;  4B5G A;  4AWN A;  2UYR X;  4L1Y A;  5DV4 A;  4C1R A;  3CJC D;  3I48 A;  1ZWX A;  4CMN A;  4FPV A;  3K55 A;  5INK A;  3G91 A;  3W2X A;  4RUW A;  2EI9 A;  4B5F A;  3L1W A;  5INQ A;  2O3H A;  2A40 B;  5CFG A;  3NGO A;  3G4T A;  3G3C A;  5INL A;  1SR4 B;  5J8N A;  5DV2 A;  3DNI A;  4GEW A;  5CFE A;  1DEW A;  3MPR A;  4QHD A;  2D1K B;  2DNJ A;  3I5V A;  5HT2 A;  1AKO A;  4B5M A;  2VOA A;  1BIX A;  4B5I A;  3WCX A;  3G0R A;  2JC4 A;  3I46 A; 
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