4B5HA

Substate bound inactive mutant of neisseria ap endonuclease in presence of metal ions
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
259
structure length
259
Chain Sequence
MLKIISANVNGIRSAYKKGFYEYIAASGTDIVCVQELKAQEADLSADMKNPHGMHGHWHCAEKRGYSGVAVYSKRKPDNVQIGMGIEEFDREGRFVRCDFGRLSVISLYLPSGSSAEERQQVKYRFLDAFYPMLEAMKNEGRDIVVCGNWNIAHQNIDLKNWKGNQKNSGFLPEEREWIGKVIHKLGWTDMWRTLYPDVPGYTWWSNRGQAYAKDVGWRIDYQMVTPELAAKAVSAHVYKDEKFSDHAPLVVEYDYAAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Neisseria meningitidis
molecule keywords PUTATIVE EXODEOXYRIBONUCLEASE
total genus 77
structure length 259
sequence length 259
ec nomenclature ec 3.1.11.2: Exodeoxyribonuclease III.
pdb deposition date 2012-08-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 4b5hA00
3G3YA 3G0AA 5DFIA 5DFFA 4FPVA 4GZ2A 4GEWA 1WDUA 3G3CA 3GA6A 2UYRX 4L1ZA 3W3DB 3I48A 4B5GA 1I9ZA 5INPA 2JC4A 4F1IA 4IEMA 3WCXA 2JC5A 1ZWXA 3W2YA 1DEWA 1DE8A 2DNJA 1VYBA 3I41A 1Y21A 2O3CA 2J63A 3MPRA 4L1YA 5DV4A 5J8NA 2ISIA 4F1HB 5A7JA 5HT2A 3I46A 3CJCD 3MTCA 5J3SA 4GYZA 2O3HA 4LNDA 2VOAA 4L21A 2DDRA 4L20A 4CMNA 3NGQA 3G2DA 3FZIA 2D1KB 5J3PA 3L1WA 5DFJA 2A40B 4AWNA 5DG0A 4GZ0A 1DNKA 4B5MA 5INOA 4B5HA 5INLA 3W2XA 3G4TA 5DFHA 4FVAA 1BIXA 4K6LF 2DDTA 4C1RA 4QH9A 3N9VA 4QHDA 2V0RA 3G38A 5INMA 3U8UA 3G6SA 5INQA 4CMLA 1E9NA 3NR8A 1HD7A 2F2FB 4QHEA 5CFGA 1YJHA 3NGNA 4PUQA 4B5FA 4B5IA 2V0SA 3G1KA 1DE9A 2XSWA 3G91A 2DDSA 3TEBA 5J3ZA 1SR4B 2A41B 5A7IA 4GZ1A 1I9YA 2A42B 3G8VA 1ATND 2A3ZB 3DNIA 5CFEA 4B5JA 4A9CA 3K55A 5EWTA 5DV2A 5J42A 3NGOA 4F1HA 3G00A 2EI9A 2IMQX 1SI6X 5INNA 1NTFA 3I5VA 4RUWA 3G0RA 4F1RA 3G2CA 2F1NA 1AKOA 5INKA 4JG3A
chains in the Genus database with same CATH superfamily
3G3YA 3G0AA 5DFIA 5DFFA 4FPVA 4GZ2A 4GEWA 1WDUA 3G3CA 3GA6A 2UYRX 4L1ZA 3W3DB 3I48A 4B5GA 1I9ZA 5INPA 2JC4A 4F1IA 4IEMA 3WCXA 2JC5A 1ZWXA 3W2YA 1DEWA 1DE8A 2DNJA 1VYBA 3I41A 1Y21A 2O3CA 2J63A 3MPRA 4L1YA 5DV4A 5J8NA 2ISIA 4F1HB 5A7JA 5HT2A 3I46A 3CJCD 3MTCA 5J3SA 4GYZA 2O3HA 4LNDA 2VOAA 4L21A 2DDRA 4L20A 4CMNA 3NGQA 3G2DA 3FZIA 2D1KB 5J3PA 3L1WA 5DFJA 2A40B 4AWNA 5DG0A 4GZ0A 1DNKA 4B5MA 5INOA 4B5HA 5INLA 3W2XA 3G4TA 5DFHA 4FVAA 1BIXA 4K6LF 2DDTA 4C1RA 4QH9A 3N9VA 4QHDA 2V0RA 3G38A 5INMA 3U8UA 3G6SA 5INQA 4CMLA 1E9NA 3NR8A 1HD7A 2F2FB 4QHEA 5CFGA 1YJHA 3NGNA 4PUQA 4B5FA 4B5IA 2V0SA 3G1KA 1DE9A 2XSWA 3G91A 2DDSA 3TEBA 5J3ZA 1SR4B 2A41B 5A7IA 4GZ1A 1I9YA 2A42B 3G8VA 1ATND 2A3ZB 3DNIA 5CFEA 4B5JA 4A9CA 3K55A 5EWTA 5DV2A 5J42A 3NGOA 4F1HA 3G00A 2EI9A 2IMQX 1SI6X 5INNA 1NTFA 3I5VA 4RUWA 3G0RA 4F1RA 3G2CA 2F1NA 1AKOA 5INKA 4JG3A
chains in the Genus database with same CATH topology
3G3YA 3G0AA 5DFIA 5DFFA 4FPVA 4GZ2A 4GEWA 1WDUA 3G3CA 3GA6A 2UYRX 4L1ZA 3W3DB 3I48A 4B5GA 1I9ZA 5INPA 2JC4A 4F1IA 4IEMA 3WCXA 2JC5A 1ZWXA 3W2YA 1DEWA 1DE8A 2DNJA 1VYBA 3I41A 1Y21A 2O3CA 2J63A 3MPRA 4L1YA 5DV4A 5J8NA 2ISIA 4F1HB 5A7JA 5HT2A 3I46A 3CJCD 3MTCA 5J3SA 4GYZA 2O3HA 4LNDA 2VOAA 4L21A 2DDRA 4L20A 4CMNA 3NGQA 3G2DA 3FZIA 2D1KB 5J3PA 3L1WA 5DFJA 2A40B 4AWNA 5DG0A 4GZ0A 1DNKA 4B5MA 5INOA 4B5HA 5INLA 3W2XA 3G4TA 5DFHA 4FVAA 1BIXA 4K6LF 2DDTA 4C1RA 4QH9A 3N9VA 4QHDA 2V0RA 3G38A 5INMA 3U8UA 3G6SA 5INQA 4CMLA 1E9NA 3NR8A 1HD7A 2F2FB 4QHEA 5CFGA 1YJHA 3NGNA 4PUQA 4B5FA 4B5IA 2V0SA 3G1KA 1DE9A 2XSWA 3G91A 2DDSA 3TEBA 5J3ZA 1SR4B 2A41B 5A7IA 4GZ1A 1I9YA 2A42B 3G8VA 1ATND 2A3ZB 3DNIA 5CFEA 4B5JA 4A9CA 3K55A 5EWTA 5DV2A 5J42A 3NGOA 4F1HA 3G00A 2EI9A 2IMQX 1SI6X 5INNA 1NTFA 3I5VA 4RUWA 3G0RA 4F1RA 3G2CA 2F1NA 1AKOA 5INKA 4JG3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3G3Y A;  3G0A A;  5DFI A;  5DFF A;  4FPV A;  4GZ2 A;  4GEW A;  1WDU A;  3G3C A;  3GA6 A;  2UYR X;  4L1Z A;  3W3D B;  3I48 A;  4B5G A;  1I9Z A;  5INP A;  2JC4 A;  4F1I A;  4IEM A;  3WCX A;  2JC5 A;  1ZWX A;  3W2Y A;  1DEW A;  1DE8 A;  2DNJ A;  1VYB A;  3I41 A;  1Y21 A;  2O3C A;  2J63 A;  3MPR A;  4L1Y A;  5DV4 A;  5J8N A;  2ISI A;  4F1H B;  5A7J A;  5HT2 A;  3I46 A;  3CJC D;  3MTC A;  5J3S A;  4GYZ A;  2O3H A;  4LND A;  2VOA A;  4L21 A;  2DDR A;  4L20 A;  4CMN A;  3NGQ A;  3G2D A;  3FZI A;  2D1K B;  5J3P A;  3L1W A;  5DFJ A;  2A40 B;  4AWN A;  5DG0 A;  4GZ0 A;  1DNK A;  4B5M A;  5INO A;  4B5H A;  5INL A;  3W2X A;  3G4T A;  5DFH A;  4FVA A;  1BIX A;  4K6L F;  2DDT A;  4C1R A;  4QH9 A;  3N9V A;  4QHD A;  2V0R A;  3G38 A;  5INM A;  3U8U A;  3G6S A;  5INQ A;  4CML A;  1E9N A;  3NR8 A;  1HD7 A;  2F2F B;  4QHE A;  5CFG A;  1YJH A;  3NGN A;  4PUQ A;  4B5F A;  4B5I A;  2V0S A;  3G1K A;  1DE9 A;  2XSW A;  3G91 A;  2DDS A;  3TEB A;  5J3Z A;  1SR4 B;  2A41 B;  5A7I A;  4GZ1 A;  1I9Y A;  2A42 B;  3G8V A;  1ATN D;  2A3Z B;  3DNI A;  5CFE A;  4B5J A;  4A9C A;  3K55 A;  5EWT A;  5DV2 A;  5J42 A;  3NGO A;  4F1H A;  3G00 A;  2EI9 A;  2IMQ X;  1SI6 X;  5INN A;  1NTF A;  3I5V A;  4RUW A;  3G0R A;  4F1R A;  3G2C A;  2F1N A;  1AKO A;  5INK A;  4JG3 A; 
#chains in the Genus database with same CATH topology
 3G3Y A;  3G0A A;  5DFI A;  5DFF A;  4FPV A;  4GZ2 A;  4GEW A;  1WDU A;  3G3C A;  3GA6 A;  2UYR X;  4L1Z A;  3W3D B;  3I48 A;  4B5G A;  1I9Z A;  5INP A;  2JC4 A;  4F1I A;  4IEM A;  3WCX A;  2JC5 A;  1ZWX A;  3W2Y A;  1DEW A;  1DE8 A;  2DNJ A;  1VYB A;  3I41 A;  1Y21 A;  2O3C A;  2J63 A;  3MPR A;  4L1Y A;  5DV4 A;  5J8N A;  2ISI A;  4F1H B;  5A7J A;  5HT2 A;  3I46 A;  3CJC D;  3MTC A;  5J3S A;  4GYZ A;  2O3H A;  4LND A;  2VOA A;  4L21 A;  2DDR A;  4L20 A;  4CMN A;  3NGQ A;  3G2D A;  3FZI A;  2D1K B;  5J3P A;  3L1W A;  5DFJ A;  2A40 B;  4AWN A;  5DG0 A;  4GZ0 A;  1DNK A;  4B5M A;  5INO A;  4B5H A;  5INL A;  3W2X A;  3G4T A;  5DFH A;  4FVA A;  1BIX A;  4K6L F;  2DDT A;  4C1R A;  4QH9 A;  3N9V A;  4QHD A;  2V0R A;  3G38 A;  5INM A;  3U8U A;  3G6S A;  5INQ A;  4CML A;  1E9N A;  3NR8 A;  1HD7 A;  2F2F B;  4QHE A;  5CFG A;  1YJH A;  3NGN A;  4PUQ A;  4B5F A;  4B5I A;  2V0S A;  3G1K A;  1DE9 A;  2XSW A;  3G91 A;  2DDS A;  3TEB A;  5J3Z A;  1SR4 B;  2A41 B;  5A7I A;  4GZ1 A;  1I9Y A;  2A42 B;  3G8V A;  1ATN D;  2A3Z B;  3DNI A;  5CFE A;  4B5J A;  4A9C A;  3K55 A;  5EWT A;  5DV2 A;  5J42 A;  3NGO A;  4F1H A;  3G00 A;  2EI9 A;  2IMQ X;  1SI6 X;  5INN A;  1NTF A;  3I5V A;  4RUW A;  3G0R A;  4F1R A;  3G2C A;  2F1N A;  1AKO A;  5INK A;  4JG3 A; 
#chains in the Genus database with same CATH homology
 3G3Y A;  3G0A A;  5DFI A;  5DFF A;  4FPV A;  4GZ2 A;  4GEW A;  1WDU A;  3G3C A;  3GA6 A;  2UYR X;  4L1Z A;  3W3D B;  3I48 A;  4B5G A;  1I9Z A;  5INP A;  2JC4 A;  4F1I A;  4IEM A;  3WCX A;  2JC5 A;  1ZWX A;  3W2Y A;  1DEW A;  1DE8 A;  2DNJ A;  1VYB A;  3I41 A;  1Y21 A;  2O3C A;  2J63 A;  3MPR A;  4L1Y A;  5DV4 A;  5J8N A;  2ISI A;  4F1H B;  5A7J A;  5HT2 A;  3I46 A;  3CJC D;  3MTC A;  5J3S A;  4GYZ A;  2O3H A;  4LND A;  2VOA A;  4L21 A;  2DDR A;  4L20 A;  4CMN A;  3NGQ A;  3G2D A;  3FZI A;  2D1K B;  5J3P A;  3L1W A;  5DFJ A;  2A40 B;  4AWN A;  5DG0 A;  4GZ0 A;  1DNK A;  4B5M A;  5INO A;  4B5H A;  5INL A;  3W2X A;  3G4T A;  5DFH A;  4FVA A;  1BIX A;  4K6L F;  2DDT A;  4C1R A;  4QH9 A;  3N9V A;  4QHD A;  2V0R A;  3G38 A;  5INM A;  3U8U A;  3G6S A;  5INQ A;  4CML A;  1E9N A;  3NR8 A;  1HD7 A;  2F2F B;  4QHE A;  5CFG A;  1YJH A;  3NGN A;  4PUQ A;  4B5F A;  4B5I A;  2V0S A;  3G1K A;  1DE9 A;  2XSW A;  3G91 A;  2DDS A;  3TEB A;  5J3Z A;  1SR4 B;  2A41 B;  5A7I A;  4GZ1 A;  1I9Y A;  2A42 B;  3G8V A;  1ATN D;  2A3Z B;  3DNI A;  5CFE A;  4B5J A;  4A9C A;  3K55 A;  5EWT A;  5DV2 A;  5J42 A;  3NGO A;  4F1H A;  3G00 A;  2EI9 A;  2IMQ X;  1SI6 X;  5INN A;  1NTF A;  3I5V A;  4RUW A;  3G0R A;  4F1R A;  3G2C A;  2F1N A;  1AKO A;  5INK A;  4JG3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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