4B5JA

Neisseria ap endonuclease bound to the substrate with an orphan adenine base
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
256
structure length
256
Chain Sequence
MLKIISANVNGIRSAYKKGFYEYIAASGADIVCVQELKAQEADLSADMKNPHGMHGHWHCAEKRGYSGVAVYSKRKPDNVQIGMGIEEFDREGRFVRCDFGRLSVISLYLPSGSSAEERQQVKYRFLDAFYPMLEAMKNEGRDIVVCGDWNIAHQNIDLKNWKGNQKNSGFLPEEREWIGKVIHKLGWTDMWRTLYPDVPGYTWWSNRGQAYAKDVGWRIDYQMVTPELAAKAVSAHVYKDEKFSDHAPLVVEYDY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Neisseria meningitidis
molecule keywords PUTATIVE EXODEOXYRIBONUCLEASE
total genus 86
structure length 256
sequence length 256
ec nomenclature ec 3.1.11.2: Exodeoxyribonuclease III.
pdb deposition date 2012-08-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 4b5jA00
4GYZA 5DV4A 1SI6X 4F1HB 2DNJA 2DDSA 3G6SA 4CMLA 1NTFA 5A7IA 2A3ZB 3NGOA 3G38A 1AKOA 4B5FA 4B5IA 4FPVA 2V0RA 4PUQA 4F1IA 2DDRA 1WDUA 3I46A 5DV2A 2XSWA 2DDTA 3I5VA 5J3PA 1YJHA 4QH9A 3G2DA 3G91A 2JC5A 4QHEA 4GZ2A 3N9VA 3TEBA 4GZ1A 4B5MA 1DE8A 2F2FB 3DNIA 4JG3A 4AWNA 4IEMA 3G1KA 1DE9A 2D1KB 2O3CA 4L21A 3G4TA 5INLA 2EI9A 5DFHA 4CMNA 5J3SA 4C1RA 5INKA 4LNDA 3I41A 3U8UA 3W2XA 1VYBA 4F1HA 3NGNA 3W2YA 3CJCD 5CFGA 3G00A 5INMA 1HD7A 3MPRA 5J3ZA 5HT2A 4L1YA 3I48A 5INOA 4A9CA 2V0SA 4B5GA 3G3YA 3G0AA 5J8NA 1E9NA 5DFJA 1DNKA 2A40B 3G8VA 2A41B 4B5JA 4L20A 5CFEA 5INNA 2A42B 3FZIA 2J63A 3W3DB 3G2CA 5J42A 1I9YA 4RUWA 3NGQA 3L1WA 2UYRX 5DFIA 2O3HA 2VOAA 1I9ZA 4GEWA 1ZWXA 4L1ZA 5DG0A 2IMQX 4GZ0A 3K55A 3MTCA 3G3CA 1BIXA 3NR8A 1Y21A 4F1RA 3GA6A 1DEWA 4QHDA 2F1NA 5A7JA 5INQA 5DFFA 5INPA 4FVAA 5EWTA 3G0RA 4B5HA 1ATND 2JC4A 3WCXA 1SR4B 2ISIA 4K6LF
chains in the Genus database with same CATH superfamily
4GYZA 5DV4A 1SI6X 4F1HB 2DNJA 2DDSA 3G6SA 4CMLA 1NTFA 5A7IA 2A3ZB 3NGOA 3G38A 1AKOA 4B5FA 4B5IA 4FPVA 2V0RA 4PUQA 4F1IA 2DDRA 1WDUA 3I46A 5DV2A 2XSWA 2DDTA 3I5VA 5J3PA 1YJHA 4QH9A 3G2DA 3G91A 2JC5A 4QHEA 4GZ2A 3N9VA 3TEBA 4GZ1A 4B5MA 1DE8A 2F2FB 3DNIA 4JG3A 4AWNA 4IEMA 3G1KA 1DE9A 2D1KB 2O3CA 4L21A 3G4TA 5INLA 2EI9A 5DFHA 4CMNA 5J3SA 4C1RA 5INKA 4LNDA 3I41A 3U8UA 3W2XA 1VYBA 4F1HA 3NGNA 3W2YA 3CJCD 5CFGA 3G00A 5INMA 1HD7A 3MPRA 5J3ZA 5HT2A 4L1YA 3I48A 5INOA 4A9CA 2V0SA 4B5GA 3G3YA 3G0AA 5J8NA 1E9NA 5DFJA 1DNKA 2A40B 3G8VA 2A41B 4B5JA 4L20A 5CFEA 5INNA 2A42B 3FZIA 2J63A 3W3DB 3G2CA 5J42A 1I9YA 4RUWA 3NGQA 3L1WA 2UYRX 5DFIA 2O3HA 2VOAA 1I9ZA 4GEWA 1ZWXA 4L1ZA 5DG0A 2IMQX 4GZ0A 3K55A 3MTCA 3G3CA 1BIXA 3NR8A 1Y21A 4F1RA 3GA6A 1DEWA 4QHDA 2F1NA 5A7JA 5INQA 5DFFA 5INPA 4FVAA 5EWTA 3G0RA 4B5HA 1ATND 2JC4A 3WCXA 1SR4B 2ISIA 4K6LF
chains in the Genus database with same CATH topology
4GYZA 5DV4A 1SI6X 4F1HB 2DNJA 2DDSA 3G6SA 4CMLA 1NTFA 5A7IA 2A3ZB 3NGOA 3G38A 1AKOA 4B5FA 4B5IA 4FPVA 2V0RA 4PUQA 4F1IA 2DDRA 1WDUA 3I46A 5DV2A 2XSWA 2DDTA 3I5VA 5J3PA 1YJHA 4QH9A 3G2DA 3G91A 2JC5A 4QHEA 4GZ2A 3N9VA 3TEBA 4GZ1A 4B5MA 1DE8A 2F2FB 3DNIA 4JG3A 4AWNA 4IEMA 3G1KA 1DE9A 2D1KB 2O3CA 4L21A 3G4TA 5INLA 2EI9A 5DFHA 4CMNA 5J3SA 4C1RA 5INKA 4LNDA 3I41A 3U8UA 3W2XA 1VYBA 4F1HA 3NGNA 3W2YA 3CJCD 5CFGA 3G00A 5INMA 1HD7A 3MPRA 5J3ZA 5HT2A 4L1YA 3I48A 5INOA 4A9CA 2V0SA 4B5GA 3G3YA 3G0AA 5J8NA 1E9NA 5DFJA 1DNKA 2A40B 3G8VA 2A41B 4B5JA 4L20A 5CFEA 5INNA 2A42B 3FZIA 2J63A 3W3DB 3G2CA 5J42A 1I9YA 4RUWA 3NGQA 3L1WA 2UYRX 5DFIA 2O3HA 2VOAA 1I9ZA 4GEWA 1ZWXA 4L1ZA 5DG0A 2IMQX 4GZ0A 3K55A 3MTCA 3G3CA 1BIXA 3NR8A 1Y21A 4F1RA 3GA6A 1DEWA 4QHDA 2F1NA 5A7JA 5INQA 5DFFA 5INPA 4FVAA 5EWTA 3G0RA 4B5HA 1ATND 2JC4A 3WCXA 1SR4B 2ISIA 4K6LF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GYZ A;  5DV4 A;  1SI6 X;  4F1H B;  2DNJ A;  2DDS A;  3G6S A;  4CML A;  1NTF A;  5A7I A;  2A3Z B;  3NGO A;  3G38 A;  1AKO A;  4B5F A;  4B5I A;  4FPV A;  2V0R A;  4PUQ A;  4F1I A;  2DDR A;  1WDU A;  3I46 A;  5DV2 A;  2XSW A;  2DDT A;  3I5V A;  5J3P A;  1YJH A;  4QH9 A;  3G2D A;  3G91 A;  2JC5 A;  4QHE A;  4GZ2 A;  3N9V A;  3TEB A;  4GZ1 A;  4B5M A;  1DE8 A;  2F2F B;  3DNI A;  4JG3 A;  4AWN A;  4IEM A;  3G1K A;  1DE9 A;  2D1K B;  2O3C A;  4L21 A;  3G4T A;  5INL A;  2EI9 A;  5DFH A;  4CMN A;  5J3S A;  4C1R A;  5INK A;  4LND A;  3I41 A;  3U8U A;  3W2X A;  1VYB A;  4F1H A;  3NGN A;  3W2Y A;  3CJC D;  5CFG A;  3G00 A;  5INM A;  1HD7 A;  3MPR A;  5J3Z A;  5HT2 A;  4L1Y A;  3I48 A;  5INO A;  4A9C A;  2V0S A;  4B5G A;  3G3Y A;  3G0A A;  5J8N A;  1E9N A;  5DFJ A;  1DNK A;  2A40 B;  3G8V A;  2A41 B;  4B5J A;  4L20 A;  5CFE A;  5INN A;  2A42 B;  3FZI A;  2J63 A;  3W3D B;  3G2C A;  5J42 A;  1I9Y A;  4RUW A;  3NGQ A;  3L1W A;  2UYR X;  5DFI A;  2O3H A;  2VOA A;  1I9Z A;  4GEW A;  1ZWX A;  4L1Z A;  5DG0 A;  2IMQ X;  4GZ0 A;  3K55 A;  3MTC A;  3G3C A;  1BIX A;  3NR8 A;  1Y21 A;  4F1R A;  3GA6 A;  1DEW A;  4QHD A;  2F1N A;  5A7J A;  5INQ A;  5DFF A;  5INP A;  4FVA A;  5EWT A;  3G0R A;  4B5H A;  1ATN D;  2JC4 A;  3WCX A;  1SR4 B;  2ISI A;  4K6L F; 
#chains in the Genus database with same CATH topology
 4GYZ A;  5DV4 A;  1SI6 X;  4F1H B;  2DNJ A;  2DDS A;  3G6S A;  4CML A;  1NTF A;  5A7I A;  2A3Z B;  3NGO A;  3G38 A;  1AKO A;  4B5F A;  4B5I A;  4FPV A;  2V0R A;  4PUQ A;  4F1I A;  2DDR A;  1WDU A;  3I46 A;  5DV2 A;  2XSW A;  2DDT A;  3I5V A;  5J3P A;  1YJH A;  4QH9 A;  3G2D A;  3G91 A;  2JC5 A;  4QHE A;  4GZ2 A;  3N9V A;  3TEB A;  4GZ1 A;  4B5M A;  1DE8 A;  2F2F B;  3DNI A;  4JG3 A;  4AWN A;  4IEM A;  3G1K A;  1DE9 A;  2D1K B;  2O3C A;  4L21 A;  3G4T A;  5INL A;  2EI9 A;  5DFH A;  4CMN A;  5J3S A;  4C1R A;  5INK A;  4LND A;  3I41 A;  3U8U A;  3W2X A;  1VYB A;  4F1H A;  3NGN A;  3W2Y A;  3CJC D;  5CFG A;  3G00 A;  5INM A;  1HD7 A;  3MPR A;  5J3Z A;  5HT2 A;  4L1Y A;  3I48 A;  5INO A;  4A9C A;  2V0S A;  4B5G A;  3G3Y A;  3G0A A;  5J8N A;  1E9N A;  5DFJ A;  1DNK A;  2A40 B;  3G8V A;  2A41 B;  4B5J A;  4L20 A;  5CFE A;  5INN A;  2A42 B;  3FZI A;  2J63 A;  3W3D B;  3G2C A;  5J42 A;  1I9Y A;  4RUW A;  3NGQ A;  3L1W A;  2UYR X;  5DFI A;  2O3H A;  2VOA A;  1I9Z A;  4GEW A;  1ZWX A;  4L1Z A;  5DG0 A;  2IMQ X;  4GZ0 A;  3K55 A;  3MTC A;  3G3C A;  1BIX A;  3NR8 A;  1Y21 A;  4F1R A;  3GA6 A;  1DEW A;  4QHD A;  2F1N A;  5A7J A;  5INQ A;  5DFF A;  5INP A;  4FVA A;  5EWT A;  3G0R A;  4B5H A;  1ATN D;  2JC4 A;  3WCX A;  1SR4 B;  2ISI A;  4K6L F; 
#chains in the Genus database with same CATH homology
 4GYZ A;  5DV4 A;  1SI6 X;  4F1H B;  2DNJ A;  2DDS A;  3G6S A;  4CML A;  1NTF A;  5A7I A;  2A3Z B;  3NGO A;  3G38 A;  1AKO A;  4B5F A;  4B5I A;  4FPV A;  2V0R A;  4PUQ A;  4F1I A;  2DDR A;  1WDU A;  3I46 A;  5DV2 A;  2XSW A;  2DDT A;  3I5V A;  5J3P A;  1YJH A;  4QH9 A;  3G2D A;  3G91 A;  2JC5 A;  4QHE A;  4GZ2 A;  3N9V A;  3TEB A;  4GZ1 A;  4B5M A;  1DE8 A;  2F2F B;  3DNI A;  4JG3 A;  4AWN A;  4IEM A;  3G1K A;  1DE9 A;  2D1K B;  2O3C A;  4L21 A;  3G4T A;  5INL A;  2EI9 A;  5DFH A;  4CMN A;  5J3S A;  4C1R A;  5INK A;  4LND A;  3I41 A;  3U8U A;  3W2X A;  1VYB A;  4F1H A;  3NGN A;  3W2Y A;  3CJC D;  5CFG A;  3G00 A;  5INM A;  1HD7 A;  3MPR A;  5J3Z A;  5HT2 A;  4L1Y A;  3I48 A;  5INO A;  4A9C A;  2V0S A;  4B5G A;  3G3Y A;  3G0A A;  5J8N A;  1E9N A;  5DFJ A;  1DNK A;  2A40 B;  3G8V A;  2A41 B;  4B5J A;  4L20 A;  5CFE A;  5INN A;  2A42 B;  3FZI A;  2J63 A;  3W3D B;  3G2C A;  5J42 A;  1I9Y A;  4RUW A;  3NGQ A;  3L1W A;  2UYR X;  5DFI A;  2O3H A;  2VOA A;  1I9Z A;  4GEW A;  1ZWX A;  4L1Z A;  5DG0 A;  2IMQ X;  4GZ0 A;  3K55 A;  3MTC A;  3G3C A;  1BIX A;  3NR8 A;  1Y21 A;  4F1R A;  3GA6 A;  1DEW A;  4QHD A;  2F1N A;  5A7J A;  5INQ A;  5DFF A;  5INP A;  4FVA A;  5EWT A;  3G0R A;  4B5H A;  1ATN D;  2JC4 A;  3WCX A;  1SR4 B;  2ISI A;  4K6L F; 
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similar chains in the Genus database (?% sequence similarity)
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