4B5MA

Neisseria ap endonuclease bound to the substrate with a cytosine orphan base
Total Genus 81
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
257
structure length
257
Chain Sequence
MLKIISANVNGIRSAYKKGFYEYIAASGADIVCVQELKAQEADLSADMKNPHGMHGHWHCAEKRGYSGVAVYSKRKPDNVQIGMGIEEFDREGRFVRCDFGRLSVISLYLPSGSSAEERQQVKYRFLDAFYPMLEAMKNEGRDIVVCGDWNIAHQNIDLKNWKGNQKNSGFLPEEREWIGKVIHKLGWTDMWRTLYPDVPGYTWWSNRGQAYAKDVGWRIDYQMVTPELAAKAVSAHVYKDEKFSDHAPLVVEYDYA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Neisseria meningitidis
molecule keywords PUTATIVE EXODEOXYRIBONUCLEASE
total genus 81
structure length 257
sequence length 257
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2012-08-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 4b5mA00
2V0RA 1NTFA 3U8UA 5J8NA 1ATND 5DV2A 5EWTA 4B5IA 3I46A 3WCXA 3I48A 3G2CA 4A9CA 3G4TA 3G38A 2EI9A 3G0RA 3DNIA 1E9NA 4GZ1A 5DFHA 5CFEA 2ISIA 2DNJA 3MTCA 5J3ZA 1VYBA 3G0AA 4QHDA 1DNKA 3GA6A 2A41B 5J3PA 4C1RA 1ZWXA 3NGQA 2J63A 3G6SA 3G3CA 2UYRX 5A7JA 3TEBA 3G2DA 3W3DB 5INOA 2VOAA 4QH9A 5INPA 1DE9A 4IEMA 3FZIA 2V0SA 4K6LF 5DFIA 5DG0A 2A3ZB 3W2XA 2F2FB 1SR4B 2A42B 5INNA 2DDSA 1WDUA 4B5GA 4B5FA 1DE8A 2O3HA 3I5VA 2XSWA 3NGOA 3G1KA 1HD7A 4B5MA 4GZ2A 3NR8A 4QHEA 4GZ0A 5DV4A 1Y21A 3I41A 2DDTA 5DFFA 5INLA 4FPVA 4GYZA 3G91A 3L1WA 4LNDA 4L20A 5DFJA 4L21A 4L1YA 4AWNA 5INKA 1DEWA 1BIXA 5INMA 4JG3A 5HT2A 3N9VA 3W2YA 3NGNA 5CFGA 2JC4A 2A40B 2O3CA 3G00A 4RUWA 2DDRA 2F1NA 4L1ZA 4CMLA 3MPRA 4B5HA 4F1HA 2IMQX 4B5JA 5J42A 4GEWA 2D1KB 5INQA 3G8VA 2JC5A 1AKOA 1YJHA 1I9ZA 5J3SA 1SI6X 4FVAA 1I9YA 4PUQA 4F1IA 3K55A 5A7IA 3CJCD 4F1HB 4F1RA 4CMNA 3G3YA
chains in the Genus database with same CATH superfamily
2V0RA 1NTFA 3U8UA 5J8NA 1ATND 5DV2A 5EWTA 4B5IA 3I46A 3WCXA 3I48A 3G2CA 4A9CA 3G4TA 3G38A 2EI9A 3G0RA 3DNIA 1E9NA 4GZ1A 5DFHA 5CFEA 2ISIA 2DNJA 3MTCA 5J3ZA 1VYBA 3G0AA 4QHDA 1DNKA 3GA6A 2A41B 5J3PA 4C1RA 1ZWXA 3NGQA 2J63A 3G6SA 3G3CA 2UYRX 5A7JA 3TEBA 3G2DA 3W3DB 5INOA 2VOAA 4QH9A 5INPA 1DE9A 4IEMA 3FZIA 2V0SA 4K6LF 5DFIA 5DG0A 2A3ZB 3W2XA 2F2FB 1SR4B 2A42B 5INNA 2DDSA 1WDUA 4B5GA 4B5FA 1DE8A 2O3HA 3I5VA 2XSWA 3NGOA 3G1KA 1HD7A 4B5MA 4GZ2A 3NR8A 4QHEA 4GZ0A 5DV4A 1Y21A 3I41A 2DDTA 5DFFA 5INLA 4FPVA 4GYZA 3G91A 3L1WA 4LNDA 4L20A 5DFJA 4L21A 4L1YA 4AWNA 5INKA 1DEWA 1BIXA 5INMA 4JG3A 5HT2A 3N9VA 3W2YA 3NGNA 5CFGA 2JC4A 2A40B 2O3CA 3G00A 4RUWA 2DDRA 2F1NA 4L1ZA 4CMLA 3MPRA 4B5HA 4F1HA 2IMQX 4B5JA 5J42A 4GEWA 2D1KB 5INQA 3G8VA 2JC5A 1AKOA 1YJHA 1I9ZA 5J3SA 1SI6X 4FVAA 1I9YA 4PUQA 4F1IA 3K55A 5A7IA 3CJCD 4F1HB 4F1RA 4CMNA 3G3YA
chains in the Genus database with same CATH topology
2V0RA 1NTFA 3U8UA 5J8NA 1ATND 5DV2A 5EWTA 4B5IA 3I46A 3WCXA 3I48A 3G2CA 4A9CA 3G4TA 3G38A 2EI9A 3G0RA 3DNIA 1E9NA 4GZ1A 5DFHA 5CFEA 2ISIA 2DNJA 3MTCA 5J3ZA 1VYBA 3G0AA 4QHDA 1DNKA 3GA6A 2A41B 5J3PA 4C1RA 1ZWXA 3NGQA 2J63A 3G6SA 3G3CA 2UYRX 5A7JA 3TEBA 3G2DA 3W3DB 5INOA 2VOAA 4QH9A 5INPA 1DE9A 4IEMA 3FZIA 2V0SA 4K6LF 5DFIA 5DG0A 2A3ZB 3W2XA 2F2FB 1SR4B 2A42B 5INNA 2DDSA 1WDUA 4B5GA 4B5FA 1DE8A 2O3HA 3I5VA 2XSWA 3NGOA 3G1KA 1HD7A 4B5MA 4GZ2A 3NR8A 4QHEA 4GZ0A 5DV4A 1Y21A 3I41A 2DDTA 5DFFA 5INLA 4FPVA 4GYZA 3G91A 3L1WA 4LNDA 4L20A 5DFJA 4L21A 4L1YA 4AWNA 5INKA 1DEWA 1BIXA 5INMA 4JG3A 5HT2A 3N9VA 3W2YA 3NGNA 5CFGA 2JC4A 2A40B 2O3CA 3G00A 4RUWA 2DDRA 2F1NA 4L1ZA 4CMLA 3MPRA 4B5HA 4F1HA 2IMQX 4B5JA 5J42A 4GEWA 2D1KB 5INQA 3G8VA 2JC5A 1AKOA 1YJHA 1I9ZA 5J3SA 1SI6X 4FVAA 1I9YA 4PUQA 4F1IA 3K55A 5A7IA 3CJCD 4F1HB 4F1RA 4CMNA 3G3YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2V0R A;  1NTF A;  3U8U A;  5J8N A;  1ATN D;  5DV2 A;  5EWT A;  4B5I A;  3I46 A;  3WCX A;  3I48 A;  3G2C A;  4A9C A;  3G4T A;  3G38 A;  2EI9 A;  3G0R A;  3DNI A;  1E9N A;  4GZ1 A;  5DFH A;  5CFE A;  2ISI A;  2DNJ A;  3MTC A;  5J3Z A;  1VYB A;  3G0A A;  4QHD A;  1DNK A;  3GA6 A;  2A41 B;  5J3P A;  4C1R A;  1ZWX A;  3NGQ A;  2J63 A;  3G6S A;  3G3C A;  2UYR X;  5A7J A;  3TEB A;  3G2D A;  3W3D B;  5INO A;  2VOA A;  4QH9 A;  5INP A;  1DE9 A;  4IEM A;  3FZI A;  2V0S A;  4K6L F;  5DFI A;  5DG0 A;  2A3Z B;  3W2X A;  2F2F B;  1SR4 B;  2A42 B;  5INN A;  2DDS A;  1WDU A;  4B5G A;  4B5F A;  1DE8 A;  2O3H A;  3I5V A;  2XSW A;  3NGO A;  3G1K A;  1HD7 A;  4B5M A;  4GZ2 A;  3NR8 A;  4QHE A;  4GZ0 A;  5DV4 A;  1Y21 A;  3I41 A;  2DDT A;  5DFF A;  5INL A;  4FPV A;  4GYZ A;  3G91 A;  3L1W A;  4LND A;  4L20 A;  5DFJ A;  4L21 A;  4L1Y A;  4AWN A;  5INK A;  1DEW A;  1BIX A;  5INM A;  4JG3 A;  5HT2 A;  3N9V A;  3W2Y A;  3NGN A;  5CFG A;  2JC4 A;  2A40 B;  2O3C A;  3G00 A;  4RUW A;  2DDR A;  2F1N A;  4L1Z A;  4CML A;  3MPR A;  4B5H A;  4F1H A;  2IMQ X;  4B5J A;  5J42 A;  4GEW A;  2D1K B;  5INQ A;  3G8V A;  2JC5 A;  1AKO A;  1YJH A;  1I9Z A;  5J3S A;  1SI6 X;  4FVA A;  1I9Y A;  4PUQ A;  4F1I A;  3K55 A;  5A7I A;  3CJC D;  4F1H B;  4F1R A;  4CMN A;  3G3Y A; 
#chains in the Genus database with same CATH topology
 2V0R A;  1NTF A;  3U8U A;  5J8N A;  1ATN D;  5DV2 A;  5EWT A;  4B5I A;  3I46 A;  3WCX A;  3I48 A;  3G2C A;  4A9C A;  3G4T A;  3G38 A;  2EI9 A;  3G0R A;  3DNI A;  1E9N A;  4GZ1 A;  5DFH A;  5CFE A;  2ISI A;  2DNJ A;  3MTC A;  5J3Z A;  1VYB A;  3G0A A;  4QHD A;  1DNK A;  3GA6 A;  2A41 B;  5J3P A;  4C1R A;  1ZWX A;  3NGQ A;  2J63 A;  3G6S A;  3G3C A;  2UYR X;  5A7J A;  3TEB A;  3G2D A;  3W3D B;  5INO A;  2VOA A;  4QH9 A;  5INP A;  1DE9 A;  4IEM A;  3FZI A;  2V0S A;  4K6L F;  5DFI A;  5DG0 A;  2A3Z B;  3W2X A;  2F2F B;  1SR4 B;  2A42 B;  5INN A;  2DDS A;  1WDU A;  4B5G A;  4B5F A;  1DE8 A;  2O3H A;  3I5V A;  2XSW A;  3NGO A;  3G1K A;  1HD7 A;  4B5M A;  4GZ2 A;  3NR8 A;  4QHE A;  4GZ0 A;  5DV4 A;  1Y21 A;  3I41 A;  2DDT A;  5DFF A;  5INL A;  4FPV A;  4GYZ A;  3G91 A;  3L1W A;  4LND A;  4L20 A;  5DFJ A;  4L21 A;  4L1Y A;  4AWN A;  5INK A;  1DEW A;  1BIX A;  5INM A;  4JG3 A;  5HT2 A;  3N9V A;  3W2Y A;  3NGN A;  5CFG A;  2JC4 A;  2A40 B;  2O3C A;  3G00 A;  4RUW A;  2DDR A;  2F1N A;  4L1Z A;  4CML A;  3MPR A;  4B5H A;  4F1H A;  2IMQ X;  4B5J A;  5J42 A;  4GEW A;  2D1K B;  5INQ A;  3G8V A;  2JC5 A;  1AKO A;  1YJH A;  1I9Z A;  5J3S A;  1SI6 X;  4FVA A;  1I9Y A;  4PUQ A;  4F1I A;  3K55 A;  5A7I A;  3CJC D;  4F1H B;  4F1R A;  4CMN A;  3G3Y A; 
#chains in the Genus database with same CATH homology
 2V0R A;  1NTF A;  3U8U A;  5J8N A;  1ATN D;  5DV2 A;  5EWT A;  4B5I A;  3I46 A;  3WCX A;  3I48 A;  3G2C A;  4A9C A;  3G4T A;  3G38 A;  2EI9 A;  3G0R A;  3DNI A;  1E9N A;  4GZ1 A;  5DFH A;  5CFE A;  2ISI A;  2DNJ A;  3MTC A;  5J3Z A;  1VYB A;  3G0A A;  4QHD A;  1DNK A;  3GA6 A;  2A41 B;  5J3P A;  4C1R A;  1ZWX A;  3NGQ A;  2J63 A;  3G6S A;  3G3C A;  2UYR X;  5A7J A;  3TEB A;  3G2D A;  3W3D B;  5INO A;  2VOA A;  4QH9 A;  5INP A;  1DE9 A;  4IEM A;  3FZI A;  2V0S A;  4K6L F;  5DFI A;  5DG0 A;  2A3Z B;  3W2X A;  2F2F B;  1SR4 B;  2A42 B;  5INN A;  2DDS A;  1WDU A;  4B5G A;  4B5F A;  1DE8 A;  2O3H A;  3I5V A;  2XSW A;  3NGO A;  3G1K A;  1HD7 A;  4B5M A;  4GZ2 A;  3NR8 A;  4QHE A;  4GZ0 A;  5DV4 A;  1Y21 A;  3I41 A;  2DDT A;  5DFF A;  5INL A;  4FPV A;  4GYZ A;  3G91 A;  3L1W A;  4LND A;  4L20 A;  5DFJ A;  4L21 A;  4L1Y A;  4AWN A;  5INK A;  1DEW A;  1BIX A;  5INM A;  4JG3 A;  5HT2 A;  3N9V A;  3W2Y A;  3NGN A;  5CFG A;  2JC4 A;  2A40 B;  2O3C A;  3G00 A;  4RUW A;  2DDR A;  2F1N A;  4L1Z A;  4CML A;  3MPR A;  4B5H A;  4F1H A;  2IMQ X;  4B5J A;  5J42 A;  4GEW A;  2D1K B;  5INQ A;  3G8V A;  2JC5 A;  1AKO A;  1YJH A;  1I9Z A;  5J3S A;  1SI6 X;  4FVA A;  1I9Y A;  4PUQ A;  4F1I A;  3K55 A;  5A7I A;  3CJC D;  4F1H B;  4F1R A;  4CMN A;  3G3Y A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...