4B5MA

Neisseria ap endonuclease bound to the substrate with a cytosine orphan base
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
257
structure length
257
Chain Sequence
MLKIISANVNGIRSAYKKGFYEYIAASGADIVCVQELKAQEADLSADMKNPHGMHGHWHCAEKRGYSGVAVYSKRKPDNVQIGMGIEEFDREGRFVRCDFGRLSVISLYLPSGSSAEERQQVKYRFLDAFYPMLEAMKNEGRDIVVCGDWNIAHQNIDLKNWKGNQKNSGFLPEEREWIGKVIHKLGWTDMWRTLYPDVPGYTWWSNRGQAYAKDVGWRIDYQMVTPELAAKAVSAHVYKDEKFSDHAPLVVEYDYA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Neisseria meningitidis
molecule keywords PUTATIVE EXODEOXYRIBONUCLEASE
total genus 81
structure length 257
sequence length 257
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2012-08-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 4b5mA00
4L21A 4GZ1A 3G4TA 4AWNA 4GYZA 5DV4A 5CFGA 3NGOA 4JG3A 5A7IA 4B5HA 1DE8A 3GA6A 3I5VA 4A9CA 3G00A 3G2CA 3NGQA 3G3YA 2IMQX 4FPVA 4QHEA 3G0AA 5INLA 2F1NA 2F2FB 5INPA 1VYBA 1ZWXA 3G1KA 5INQA 2V0SA 5CFEA 3G8VA 4LNDA 5INKA 3WCXA 2DDRA 3L1WA 1E9NA 5DFHA 5DFIA 4FVAA 5DFJA 1BIXA 1WDUA 4B5MA 2A3ZB 1I9YA 3MPRA 5A7JA 3I48A 2XSWA 2ISIA 4F1HB 1DE9A 3MTCA 2O3HA 1DNKA 3CJCD 5J3SA 1AKOA 4CMLA 4QH9A 1SI6X 4L1ZA 5INOA 2V0RA 3NR8A 3G3CA 3G0RA 4QHDA 2UYRX 2VOAA 4F1HA 4F1RA 1DEWA 4F1IA 2JC4A 4B5FA 1ATND 3W3DB 5DFFA 3W2YA 1SR4B 1NTFA 3W2XA 4C1RA 5HT2A 5INMA 4RUWA 2EI9A 1Y21A 3I41A 2DDTA 3U8UA 1HD7A 3G2DA 3I46A 5J3ZA 4IEMA 5EWTA 4CMNA 5INNA 2J63A 2JC5A 2A40B 2DDSA 3K55A 3TEBA 4L1YA 2O3CA 3NGNA 4GZ2A 4B5JA 4K6LF 3G91A 3DNIA 3G38A 3G6SA 4GEWA 5DV2A 1I9ZA 5J42A 2A42B 4PUQA 5J3PA 5J8NA 4B5GA 4B5IA 2DNJA 4L20A 1YJHA 3FZIA 2D1KB 2A41B 4GZ0A 5DG0A 3N9VA
chains in the Genus database with same CATH superfamily
4L21A 4GZ1A 3G4TA 4AWNA 4GYZA 5DV4A 5CFGA 3NGOA 4JG3A 5A7IA 4B5HA 1DE8A 3GA6A 3I5VA 4A9CA 3G00A 3G2CA 3NGQA 3G3YA 2IMQX 4FPVA 4QHEA 3G0AA 5INLA 2F1NA 2F2FB 5INPA 1VYBA 1ZWXA 3G1KA 5INQA 2V0SA 5CFEA 3G8VA 4LNDA 5INKA 3WCXA 2DDRA 3L1WA 1E9NA 5DFHA 5DFIA 4FVAA 5DFJA 1BIXA 1WDUA 4B5MA 2A3ZB 1I9YA 3MPRA 5A7JA 3I48A 2XSWA 2ISIA 4F1HB 1DE9A 3MTCA 2O3HA 1DNKA 3CJCD 5J3SA 1AKOA 4CMLA 4QH9A 1SI6X 4L1ZA 5INOA 2V0RA 3NR8A 3G3CA 3G0RA 4QHDA 2UYRX 2VOAA 4F1HA 4F1RA 1DEWA 4F1IA 2JC4A 4B5FA 1ATND 3W3DB 5DFFA 3W2YA 1SR4B 1NTFA 3W2XA 4C1RA 5HT2A 5INMA 4RUWA 2EI9A 1Y21A 3I41A 2DDTA 3U8UA 1HD7A 3G2DA 3I46A 5J3ZA 4IEMA 5EWTA 4CMNA 5INNA 2J63A 2JC5A 2A40B 2DDSA 3K55A 3TEBA 4L1YA 2O3CA 3NGNA 4GZ2A 4B5JA 4K6LF 3G91A 3DNIA 3G38A 3G6SA 4GEWA 5DV2A 1I9ZA 5J42A 2A42B 4PUQA 5J3PA 5J8NA 4B5GA 4B5IA 2DNJA 4L20A 1YJHA 3FZIA 2D1KB 2A41B 4GZ0A 5DG0A 3N9VA
chains in the Genus database with same CATH topology
4L21A 4GZ1A 3G4TA 4AWNA 4GYZA 5DV4A 5CFGA 3NGOA 4JG3A 5A7IA 4B5HA 1DE8A 3GA6A 3I5VA 4A9CA 3G00A 3G2CA 3NGQA 3G3YA 2IMQX 4FPVA 4QHEA 3G0AA 5INLA 2F1NA 2F2FB 5INPA 1VYBA 1ZWXA 3G1KA 5INQA 2V0SA 5CFEA 3G8VA 4LNDA 5INKA 3WCXA 2DDRA 3L1WA 1E9NA 5DFHA 5DFIA 4FVAA 5DFJA 1BIXA 1WDUA 4B5MA 2A3ZB 1I9YA 3MPRA 5A7JA 3I48A 2XSWA 2ISIA 4F1HB 1DE9A 3MTCA 2O3HA 1DNKA 3CJCD 5J3SA 1AKOA 4CMLA 4QH9A 1SI6X 4L1ZA 5INOA 2V0RA 3NR8A 3G3CA 3G0RA 4QHDA 2UYRX 2VOAA 4F1HA 4F1RA 1DEWA 4F1IA 2JC4A 4B5FA 1ATND 3W3DB 5DFFA 3W2YA 1SR4B 1NTFA 3W2XA 4C1RA 5HT2A 5INMA 4RUWA 2EI9A 1Y21A 3I41A 2DDTA 3U8UA 1HD7A 3G2DA 3I46A 5J3ZA 4IEMA 5EWTA 4CMNA 5INNA 2J63A 2JC5A 2A40B 2DDSA 3K55A 3TEBA 4L1YA 2O3CA 3NGNA 4GZ2A 4B5JA 4K6LF 3G91A 3DNIA 3G38A 3G6SA 4GEWA 5DV2A 1I9ZA 5J42A 2A42B 4PUQA 5J3PA 5J8NA 4B5GA 4B5IA 2DNJA 4L20A 1YJHA 3FZIA 2D1KB 2A41B 4GZ0A 5DG0A 3N9VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4L21 A;  4GZ1 A;  3G4T A;  4AWN A;  4GYZ A;  5DV4 A;  5CFG A;  3NGO A;  4JG3 A;  5A7I A;  4B5H A;  1DE8 A;  3GA6 A;  3I5V A;  4A9C A;  3G00 A;  3G2C A;  3NGQ A;  3G3Y A;  2IMQ X;  4FPV A;  4QHE A;  3G0A A;  5INL A;  2F1N A;  2F2F B;  5INP A;  1VYB A;  1ZWX A;  3G1K A;  5INQ A;  2V0S A;  5CFE A;  3G8V A;  4LND A;  5INK A;  3WCX A;  2DDR A;  3L1W A;  1E9N A;  5DFH A;  5DFI A;  4FVA A;  5DFJ A;  1BIX A;  1WDU A;  4B5M A;  2A3Z B;  1I9Y A;  3MPR A;  5A7J A;  3I48 A;  2XSW A;  2ISI A;  4F1H B;  1DE9 A;  3MTC A;  2O3H A;  1DNK A;  3CJC D;  5J3S A;  1AKO A;  4CML A;  4QH9 A;  1SI6 X;  4L1Z A;  5INO A;  2V0R A;  3NR8 A;  3G3C A;  3G0R A;  4QHD A;  2UYR X;  2VOA A;  4F1H A;  4F1R A;  1DEW A;  4F1I A;  2JC4 A;  4B5F A;  1ATN D;  3W3D B;  5DFF A;  3W2Y A;  1SR4 B;  1NTF A;  3W2X A;  4C1R A;  5HT2 A;  5INM A;  4RUW A;  2EI9 A;  1Y21 A;  3I41 A;  2DDT A;  3U8U A;  1HD7 A;  3G2D A;  3I46 A;  5J3Z A;  4IEM A;  5EWT A;  4CMN A;  5INN A;  2J63 A;  2JC5 A;  2A40 B;  2DDS A;  3K55 A;  3TEB A;  4L1Y A;  2O3C A;  3NGN A;  4GZ2 A;  4B5J A;  4K6L F;  3G91 A;  3DNI A;  3G38 A;  3G6S A;  4GEW A;  5DV2 A;  1I9Z A;  5J42 A;  2A42 B;  4PUQ A;  5J3P A;  5J8N A;  4B5G A;  4B5I A;  2DNJ A;  4L20 A;  1YJH A;  3FZI A;  2D1K B;  2A41 B;  4GZ0 A;  5DG0 A;  3N9V A; 
#chains in the Genus database with same CATH topology
 4L21 A;  4GZ1 A;  3G4T A;  4AWN A;  4GYZ A;  5DV4 A;  5CFG A;  3NGO A;  4JG3 A;  5A7I A;  4B5H A;  1DE8 A;  3GA6 A;  3I5V A;  4A9C A;  3G00 A;  3G2C A;  3NGQ A;  3G3Y A;  2IMQ X;  4FPV A;  4QHE A;  3G0A A;  5INL A;  2F1N A;  2F2F B;  5INP A;  1VYB A;  1ZWX A;  3G1K A;  5INQ A;  2V0S A;  5CFE A;  3G8V A;  4LND A;  5INK A;  3WCX A;  2DDR A;  3L1W A;  1E9N A;  5DFH A;  5DFI A;  4FVA A;  5DFJ A;  1BIX A;  1WDU A;  4B5M A;  2A3Z B;  1I9Y A;  3MPR A;  5A7J A;  3I48 A;  2XSW A;  2ISI A;  4F1H B;  1DE9 A;  3MTC A;  2O3H A;  1DNK A;  3CJC D;  5J3S A;  1AKO A;  4CML A;  4QH9 A;  1SI6 X;  4L1Z A;  5INO A;  2V0R A;  3NR8 A;  3G3C A;  3G0R A;  4QHD A;  2UYR X;  2VOA A;  4F1H A;  4F1R A;  1DEW A;  4F1I A;  2JC4 A;  4B5F A;  1ATN D;  3W3D B;  5DFF A;  3W2Y A;  1SR4 B;  1NTF A;  3W2X A;  4C1R A;  5HT2 A;  5INM A;  4RUW A;  2EI9 A;  1Y21 A;  3I41 A;  2DDT A;  3U8U A;  1HD7 A;  3G2D A;  3I46 A;  5J3Z A;  4IEM A;  5EWT A;  4CMN A;  5INN A;  2J63 A;  2JC5 A;  2A40 B;  2DDS A;  3K55 A;  3TEB A;  4L1Y A;  2O3C A;  3NGN A;  4GZ2 A;  4B5J A;  4K6L F;  3G91 A;  3DNI A;  3G38 A;  3G6S A;  4GEW A;  5DV2 A;  1I9Z A;  5J42 A;  2A42 B;  4PUQ A;  5J3P A;  5J8N A;  4B5G A;  4B5I A;  2DNJ A;  4L20 A;  1YJH A;  3FZI A;  2D1K B;  2A41 B;  4GZ0 A;  5DG0 A;  3N9V A; 
#chains in the Genus database with same CATH homology
 4L21 A;  4GZ1 A;  3G4T A;  4AWN A;  4GYZ A;  5DV4 A;  5CFG A;  3NGO A;  4JG3 A;  5A7I A;  4B5H A;  1DE8 A;  3GA6 A;  3I5V A;  4A9C A;  3G00 A;  3G2C A;  3NGQ A;  3G3Y A;  2IMQ X;  4FPV A;  4QHE A;  3G0A A;  5INL A;  2F1N A;  2F2F B;  5INP A;  1VYB A;  1ZWX A;  3G1K A;  5INQ A;  2V0S A;  5CFE A;  3G8V A;  4LND A;  5INK A;  3WCX A;  2DDR A;  3L1W A;  1E9N A;  5DFH A;  5DFI A;  4FVA A;  5DFJ A;  1BIX A;  1WDU A;  4B5M A;  2A3Z B;  1I9Y A;  3MPR A;  5A7J A;  3I48 A;  2XSW A;  2ISI A;  4F1H B;  1DE9 A;  3MTC A;  2O3H A;  1DNK A;  3CJC D;  5J3S A;  1AKO A;  4CML A;  4QH9 A;  1SI6 X;  4L1Z A;  5INO A;  2V0R A;  3NR8 A;  3G3C A;  3G0R A;  4QHD A;  2UYR X;  2VOA A;  4F1H A;  4F1R A;  1DEW A;  4F1I A;  2JC4 A;  4B5F A;  1ATN D;  3W3D B;  5DFF A;  3W2Y A;  1SR4 B;  1NTF A;  3W2X A;  4C1R A;  5HT2 A;  5INM A;  4RUW A;  2EI9 A;  1Y21 A;  3I41 A;  2DDT A;  3U8U A;  1HD7 A;  3G2D A;  3I46 A;  5J3Z A;  4IEM A;  5EWT A;  4CMN A;  5INN A;  2J63 A;  2JC5 A;  2A40 B;  2DDS A;  3K55 A;  3TEB A;  4L1Y A;  2O3C A;  3NGN A;  4GZ2 A;  4B5J A;  4K6L F;  3G91 A;  3DNI A;  3G38 A;  3G6S A;  4GEW A;  5DV2 A;  1I9Z A;  5J42 A;  2A42 B;  4PUQ A;  5J3P A;  5J8N A;  4B5G A;  4B5I A;  2DNJ A;  4L20 A;  1YJH A;  3FZI A;  2D1K B;  2A41 B;  4GZ0 A;  5DG0 A;  3N9V A; 
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similar chains in the pdb database (?% sequence similarity)

 
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