4CMNA

Crystal structure of ocrl in complex with a phosphate ion
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
341
structure length
339
Chain Sequence
REGLIKHILAKREKEYVNIQTFRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNLPQLNIMKHEVVIWLGDLNYRLGMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVDERRYRKVFEDSVRIMDRMEN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Phosphoinositide Substrate Recognition, Catalysis, and Membrane Interactions in Human Inositol Polyphosphate 5-Phosphatases.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords INOSITOL POLYPHOSPHATE 5-PHOSPHATASE OCRL-1
total genus 101
structure length 339
sequence length 341
ec nomenclature ec 3.1.3.36: Phosphoinositide 5-phosphatase.
pdb deposition date 2014-01-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 4cmnA00
3G38A 1I9YA 4GYZA 1BIXA 1NTFA 1ATND 3W2XA 2V0RA 5J3SA 4F1HA 2F1NA 5CFGA 1DEWA 3G0RA 4QHDA 4IEMA 1Y21A 4QH9A 5DG0A 4GZ0A 5DFIA 4F1IA 4RUWA 2JC4A 3L1WA 4L21A 3G4TA 2D1KB 1DNKA 1YJHA 4L1ZA 5DV4A 2XSWA 3NGNA 2J63A 3G6SA 3DNIA 3G3YA 1DE9A 1AKOA 5J8NA 2A41B 5J3ZA 3W3DB 4B5HA 2VOAA 1WDUA 2F2FB 4CMNA 2A40B 4FVAA 3G2DA 1SR4B 2O3CA 5INLA 5CFEA 5INQA 5INMA 3G1KA 4GZ2A 5INOA 2A42B 1HD7A 3TEBA 2O3HA 2ISIA 3N9VA 4CMLA 3MPRA 3NGOA 5DFFA 4L20A 3NR8A 3I41A 4B5JA 2DNJA 1DE8A 4C1RA 5J42A 2JC5A 3G3CA 3G0AA 5EWTA 4JG3A 2DDTA 5INPA 4B5GA 5INNA 5A7IA 5INKA 1SI6X 4F1RA 3WCXA 3GA6A 3I5VA 4LNDA 4FPVA 3U8UA 3W2YA 3G91A 4AWNA 3I46A 5DFHA 4B5FA 5HT2A 5J3PA 3CJCD 2DDRA 4B5IA 1I9ZA 2UYRX 4GEWA 2IMQX 2DDSA 4K6LF 5A7JA 4QHEA 4A9CA 4F1HB 3G2CA 5DFJA 3I48A 3G8VA 3G00A 2V0SA 3K55A 3FZIA 3MTCA 1E9NA 1VYBA 4B5MA 2EI9A 4GZ1A 5DV2A 4PUQA 3NGQA 4L1YA 2A3ZB 1ZWXA
chains in the Genus database with same CATH superfamily
3G38A 1I9YA 4GYZA 1BIXA 1NTFA 1ATND 3W2XA 2V0RA 5J3SA 4F1HA 2F1NA 5CFGA 1DEWA 3G0RA 4QHDA 4IEMA 1Y21A 4QH9A 5DG0A 4GZ0A 5DFIA 4F1IA 4RUWA 2JC4A 3L1WA 4L21A 3G4TA 2D1KB 1DNKA 1YJHA 4L1ZA 5DV4A 2XSWA 3NGNA 2J63A 3G6SA 3DNIA 3G3YA 1DE9A 1AKOA 5J8NA 2A41B 5J3ZA 3W3DB 4B5HA 2VOAA 1WDUA 2F2FB 4CMNA 2A40B 4FVAA 3G2DA 1SR4B 2O3CA 5INLA 5CFEA 5INQA 5INMA 3G1KA 4GZ2A 5INOA 2A42B 1HD7A 3TEBA 2O3HA 2ISIA 3N9VA 4CMLA 3MPRA 3NGOA 5DFFA 4L20A 3NR8A 3I41A 4B5JA 2DNJA 1DE8A 4C1RA 5J42A 2JC5A 3G3CA 3G0AA 5EWTA 4JG3A 2DDTA 5INPA 4B5GA 5INNA 5A7IA 5INKA 1SI6X 4F1RA 3WCXA 3GA6A 3I5VA 4LNDA 4FPVA 3U8UA 3W2YA 3G91A 4AWNA 3I46A 5DFHA 4B5FA 5HT2A 5J3PA 3CJCD 2DDRA 4B5IA 1I9ZA 2UYRX 4GEWA 2IMQX 2DDSA 4K6LF 5A7JA 4QHEA 4A9CA 4F1HB 3G2CA 5DFJA 3I48A 3G8VA 3G00A 2V0SA 3K55A 3FZIA 3MTCA 1E9NA 1VYBA 4B5MA 2EI9A 4GZ1A 5DV2A 4PUQA 3NGQA 4L1YA 2A3ZB 1ZWXA
chains in the Genus database with same CATH topology
3G38A 1I9YA 4GYZA 1BIXA 1NTFA 1ATND 3W2XA 2V0RA 5J3SA 4F1HA 2F1NA 5CFGA 1DEWA 3G0RA 4QHDA 4IEMA 1Y21A 4QH9A 5DG0A 4GZ0A 5DFIA 4F1IA 4RUWA 2JC4A 3L1WA 4L21A 3G4TA 2D1KB 1DNKA 1YJHA 4L1ZA 5DV4A 2XSWA 3NGNA 2J63A 3G6SA 3DNIA 3G3YA 1DE9A 1AKOA 5J8NA 2A41B 5J3ZA 3W3DB 4B5HA 2VOAA 1WDUA 2F2FB 4CMNA 2A40B 4FVAA 3G2DA 1SR4B 2O3CA 5INLA 5CFEA 5INQA 5INMA 3G1KA 4GZ2A 5INOA 2A42B 1HD7A 3TEBA 2O3HA 2ISIA 3N9VA 4CMLA 3MPRA 3NGOA 5DFFA 4L20A 3NR8A 3I41A 4B5JA 2DNJA 1DE8A 4C1RA 5J42A 2JC5A 3G3CA 3G0AA 5EWTA 4JG3A 2DDTA 5INPA 4B5GA 5INNA 5A7IA 5INKA 1SI6X 4F1RA 3WCXA 3GA6A 3I5VA 4LNDA 4FPVA 3U8UA 3W2YA 3G91A 4AWNA 3I46A 5DFHA 4B5FA 5HT2A 5J3PA 3CJCD 2DDRA 4B5IA 1I9ZA 2UYRX 4GEWA 2IMQX 2DDSA 4K6LF 5A7JA 4QHEA 4A9CA 4F1HB 3G2CA 5DFJA 3I48A 3G8VA 3G00A 2V0SA 3K55A 3FZIA 3MTCA 1E9NA 1VYBA 4B5MA 2EI9A 4GZ1A 5DV2A 4PUQA 3NGQA 4L1YA 2A3ZB 1ZWXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3G38 A;  1I9Y A;  4GYZ A;  1BIX A;  1NTF A;  1ATN D;  3W2X A;  2V0R A;  5J3S A;  4F1H A;  2F1N A;  5CFG A;  1DEW A;  3G0R A;  4QHD A;  4IEM A;  1Y21 A;  4QH9 A;  5DG0 A;  4GZ0 A;  5DFI A;  4F1I A;  4RUW A;  2JC4 A;  3L1W A;  4L21 A;  3G4T A;  2D1K B;  1DNK A;  1YJH A;  4L1Z A;  5DV4 A;  2XSW A;  3NGN A;  2J63 A;  3G6S A;  3DNI A;  3G3Y A;  1DE9 A;  1AKO A;  5J8N A;  2A41 B;  5J3Z A;  3W3D B;  4B5H A;  2VOA A;  1WDU A;  2F2F B;  4CMN A;  2A40 B;  4FVA A;  3G2D A;  1SR4 B;  2O3C A;  5INL A;  5CFE A;  5INQ A;  5INM A;  3G1K A;  4GZ2 A;  5INO A;  2A42 B;  1HD7 A;  3TEB A;  2O3H A;  2ISI A;  3N9V A;  4CML A;  3MPR A;  3NGO A;  5DFF A;  4L20 A;  3NR8 A;  3I41 A;  4B5J A;  2DNJ A;  1DE8 A;  4C1R A;  5J42 A;  2JC5 A;  3G3C A;  3G0A A;  5EWT A;  4JG3 A;  2DDT A;  5INP A;  4B5G A;  5INN A;  5A7I A;  5INK A;  1SI6 X;  4F1R A;  3WCX A;  3GA6 A;  3I5V A;  4LND A;  4FPV A;  3U8U A;  3W2Y A;  3G91 A;  4AWN A;  3I46 A;  5DFH A;  4B5F A;  5HT2 A;  5J3P A;  3CJC D;  2DDR A;  4B5I A;  1I9Z A;  2UYR X;  4GEW A;  2IMQ X;  2DDS A;  4K6L F;  5A7J A;  4QHE A;  4A9C A;  4F1H B;  3G2C A;  5DFJ A;  3I48 A;  3G8V A;  3G00 A;  2V0S A;  3K55 A;  3FZI A;  3MTC A;  1E9N A;  1VYB A;  4B5M A;  2EI9 A;  4GZ1 A;  5DV2 A;  4PUQ A;  3NGQ A;  4L1Y A;  2A3Z B;  1ZWX A; 
#chains in the Genus database with same CATH topology
 3G38 A;  1I9Y A;  4GYZ A;  1BIX A;  1NTF A;  1ATN D;  3W2X A;  2V0R A;  5J3S A;  4F1H A;  2F1N A;  5CFG A;  1DEW A;  3G0R A;  4QHD A;  4IEM A;  1Y21 A;  4QH9 A;  5DG0 A;  4GZ0 A;  5DFI A;  4F1I A;  4RUW A;  2JC4 A;  3L1W A;  4L21 A;  3G4T A;  2D1K B;  1DNK A;  1YJH A;  4L1Z A;  5DV4 A;  2XSW A;  3NGN A;  2J63 A;  3G6S A;  3DNI A;  3G3Y A;  1DE9 A;  1AKO A;  5J8N A;  2A41 B;  5J3Z A;  3W3D B;  4B5H A;  2VOA A;  1WDU A;  2F2F B;  4CMN A;  2A40 B;  4FVA A;  3G2D A;  1SR4 B;  2O3C A;  5INL A;  5CFE A;  5INQ A;  5INM A;  3G1K A;  4GZ2 A;  5INO A;  2A42 B;  1HD7 A;  3TEB A;  2O3H A;  2ISI A;  3N9V A;  4CML A;  3MPR A;  3NGO A;  5DFF A;  4L20 A;  3NR8 A;  3I41 A;  4B5J A;  2DNJ A;  1DE8 A;  4C1R A;  5J42 A;  2JC5 A;  3G3C A;  3G0A A;  5EWT A;  4JG3 A;  2DDT A;  5INP A;  4B5G A;  5INN A;  5A7I A;  5INK A;  1SI6 X;  4F1R A;  3WCX A;  3GA6 A;  3I5V A;  4LND A;  4FPV A;  3U8U A;  3W2Y A;  3G91 A;  4AWN A;  3I46 A;  5DFH A;  4B5F A;  5HT2 A;  5J3P A;  3CJC D;  2DDR A;  4B5I A;  1I9Z A;  2UYR X;  4GEW A;  2IMQ X;  2DDS A;  4K6L F;  5A7J A;  4QHE A;  4A9C A;  4F1H B;  3G2C A;  5DFJ A;  3I48 A;  3G8V A;  3G00 A;  2V0S A;  3K55 A;  3FZI A;  3MTC A;  1E9N A;  1VYB A;  4B5M A;  2EI9 A;  4GZ1 A;  5DV2 A;  4PUQ A;  3NGQ A;  4L1Y A;  2A3Z B;  1ZWX A; 
#chains in the Genus database with same CATH homology
 3G38 A;  1I9Y A;  4GYZ A;  1BIX A;  1NTF A;  1ATN D;  3W2X A;  2V0R A;  5J3S A;  4F1H A;  2F1N A;  5CFG A;  1DEW A;  3G0R A;  4QHD A;  4IEM A;  1Y21 A;  4QH9 A;  5DG0 A;  4GZ0 A;  5DFI A;  4F1I A;  4RUW A;  2JC4 A;  3L1W A;  4L21 A;  3G4T A;  2D1K B;  1DNK A;  1YJH A;  4L1Z A;  5DV4 A;  2XSW A;  3NGN A;  2J63 A;  3G6S A;  3DNI A;  3G3Y A;  1DE9 A;  1AKO A;  5J8N A;  2A41 B;  5J3Z A;  3W3D B;  4B5H A;  2VOA A;  1WDU A;  2F2F B;  4CMN A;  2A40 B;  4FVA A;  3G2D A;  1SR4 B;  2O3C A;  5INL A;  5CFE A;  5INQ A;  5INM A;  3G1K A;  4GZ2 A;  5INO A;  2A42 B;  1HD7 A;  3TEB A;  2O3H A;  2ISI A;  3N9V A;  4CML A;  3MPR A;  3NGO A;  5DFF A;  4L20 A;  3NR8 A;  3I41 A;  4B5J A;  2DNJ A;  1DE8 A;  4C1R A;  5J42 A;  2JC5 A;  3G3C A;  3G0A A;  5EWT A;  4JG3 A;  2DDT A;  5INP A;  4B5G A;  5INN A;  5A7I A;  5INK A;  1SI6 X;  4F1R A;  3WCX A;  3GA6 A;  3I5V A;  4LND A;  4FPV A;  3U8U A;  3W2Y A;  3G91 A;  4AWN A;  3I46 A;  5DFH A;  4B5F A;  5HT2 A;  5J3P A;  3CJC D;  2DDR A;  4B5I A;  1I9Z A;  2UYR X;  4GEW A;  2IMQ X;  2DDS A;  4K6L F;  5A7J A;  4QHE A;  4A9C A;  4F1H B;  3G2C A;  5DFJ A;  3I48 A;  3G8V A;  3G00 A;  2V0S A;  3K55 A;  3FZI A;  3MTC A;  1E9N A;  1VYB A;  4B5M A;  2EI9 A;  4GZ1 A;  5DV2 A;  4PUQ A;  3NGQ A;  4L1Y A;  2A3Z B;  1ZWX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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