4FVAA

Crystal structure of truncated caenorhabditis elegans tdp2
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
249
structure length
249
Chain Sequence
DLKGFEVSVMSWNIDGLDGRSLLTRMKAVAHIVKNVNPDILFLQEVVDRDLAPIDKLQSLYKIYYSNKGCQYYTAILVSKMFDVEKHDVIHFQNSGMYRTLQILEGSIGGLKVFLLNTHLESTREHRPQRCAQFGFCMDKVREIIAQNPGALVFFGGDLNLRDEEVSRVPDGVKDAWEAAGSDNKTKFTWDTFKNDNKQGFHGAKMRFDRLYWSGPLDKVKFTLEGRQRIRSCLCFPSDHWAINATFFA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2.
pubmed doi rcsb
molecule tags Hydrolase
source organism Caenorhabditis elegans
molecule keywords 5'-tyrosyl-DNA phosphodiesterase
total genus 81
structure length 249
sequence length 249
chains with identical sequence B, C, D
ec nomenclature ec 3.1.4.-:
pdb deposition date 2012-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 4fvaA00
1SR4B 4GZ0A 5CFEA 3W2YA 4QH9A 5DFIA 4A9CA 3K55A 1NTFA 5J3SA 2DDSA 3G38A 3FZIA 3G8VA 3NGQA 1DE8A 1I9ZA 2A42B 2O3CA 3G4TA 4JG3A 4F1RA 4F1HB 3CJCD 4QHEA 3G3YA 1E9NA 2IMQX 3G2CA 5HT2A 3I5VA 2V0RA 5DV4A 2A3ZB 2O3HA 4L1YA 1ZWXA 2JC5A 3GA6A 1Y21A 5A7IA 3W3DB 3NGOA 4LNDA 4GZ2A 2DDTA 5INMA 2EI9A 3MPRA 5DV2A 1BIXA 2JC4A 1ATND 3G91A 4K6LF 3N9VA 4PUQA 5J42A 2J63A 1YJHA 2DNJA 1WDUA 4GYZA 3I48A 4CMNA 4L20A 4L1ZA 5INLA 1DEWA 2UYRX 5CFGA 4RUWA 4IEMA 4F1HA 3I46A 5J3ZA 5INQA 5INNA 2VOAA 2DDRA 3MTCA 3G3CA 5INOA 5DFHA 4QHDA 3NGNA 1VYBA 3WCXA 3TEBA 3G2DA 4FPVA 1SI6X 1HD7A 4GZ1A 4F1IA 5INKA 3U8UA 3G0AA 5A7JA 5J3PA 3L1WA 4B5MA 4FVAA 4B5HA 1I9YA 5EWTA 3G0RA 3G6SA 4B5FA 4L21A 4CMLA 5J8NA 2D1KB 4B5IA 5DG0A 4B5GA 4B5JA 4C1RA 3I41A 5DFFA 3W2XA 4GEWA 5DFJA 3NR8A 2A40B 4AWNA 2F1NA 2XSWA 2V0SA 2ISIA 2A41B 1DE9A 3DNIA 5INPA 1DNKA 3G1KA 3G00A 2F2FB 1AKOA
chains in the Genus database with same CATH superfamily
1SR4B 4GZ0A 5CFEA 3W2YA 4QH9A 5DFIA 4A9CA 3K55A 1NTFA 5J3SA 2DDSA 3G38A 3FZIA 3G8VA 3NGQA 1DE8A 1I9ZA 2A42B 2O3CA 3G4TA 4JG3A 4F1RA 4F1HB 3CJCD 4QHEA 3G3YA 1E9NA 2IMQX 3G2CA 5HT2A 3I5VA 2V0RA 5DV4A 2A3ZB 2O3HA 4L1YA 1ZWXA 2JC5A 3GA6A 1Y21A 5A7IA 3W3DB 3NGOA 4LNDA 4GZ2A 2DDTA 5INMA 2EI9A 3MPRA 5DV2A 1BIXA 2JC4A 1ATND 3G91A 4K6LF 3N9VA 4PUQA 5J42A 2J63A 1YJHA 2DNJA 1WDUA 4GYZA 3I48A 4CMNA 4L20A 4L1ZA 5INLA 1DEWA 2UYRX 5CFGA 4RUWA 4IEMA 4F1HA 3I46A 5J3ZA 5INQA 5INNA 2VOAA 2DDRA 3MTCA 3G3CA 5INOA 5DFHA 4QHDA 3NGNA 1VYBA 3WCXA 3TEBA 3G2DA 4FPVA 1SI6X 1HD7A 4GZ1A 4F1IA 5INKA 3U8UA 3G0AA 5A7JA 5J3PA 3L1WA 4B5MA 4FVAA 4B5HA 1I9YA 5EWTA 3G0RA 3G6SA 4B5FA 4L21A 4CMLA 5J8NA 2D1KB 4B5IA 5DG0A 4B5GA 4B5JA 4C1RA 3I41A 5DFFA 3W2XA 4GEWA 5DFJA 3NR8A 2A40B 4AWNA 2F1NA 2XSWA 2V0SA 2ISIA 2A41B 1DE9A 3DNIA 5INPA 1DNKA 3G1KA 3G00A 2F2FB 1AKOA
chains in the Genus database with same CATH topology
1SR4B 4GZ0A 5CFEA 3W2YA 4QH9A 5DFIA 4A9CA 3K55A 1NTFA 5J3SA 2DDSA 3G38A 3FZIA 3G8VA 3NGQA 1DE8A 1I9ZA 2A42B 2O3CA 3G4TA 4JG3A 4F1RA 4F1HB 3CJCD 4QHEA 3G3YA 1E9NA 2IMQX 3G2CA 5HT2A 3I5VA 2V0RA 5DV4A 2A3ZB 2O3HA 4L1YA 1ZWXA 2JC5A 3GA6A 1Y21A 5A7IA 3W3DB 3NGOA 4LNDA 4GZ2A 2DDTA 5INMA 2EI9A 3MPRA 5DV2A 1BIXA 2JC4A 1ATND 3G91A 4K6LF 3N9VA 4PUQA 5J42A 2J63A 1YJHA 2DNJA 1WDUA 4GYZA 3I48A 4CMNA 4L20A 4L1ZA 5INLA 1DEWA 2UYRX 5CFGA 4RUWA 4IEMA 4F1HA 3I46A 5J3ZA 5INQA 5INNA 2VOAA 2DDRA 3MTCA 3G3CA 5INOA 5DFHA 4QHDA 3NGNA 1VYBA 3WCXA 3TEBA 3G2DA 4FPVA 1SI6X 1HD7A 4GZ1A 4F1IA 5INKA 3U8UA 3G0AA 5A7JA 5J3PA 3L1WA 4B5MA 4FVAA 4B5HA 1I9YA 5EWTA 3G0RA 3G6SA 4B5FA 4L21A 4CMLA 5J8NA 2D1KB 4B5IA 5DG0A 4B5GA 4B5JA 4C1RA 3I41A 5DFFA 3W2XA 4GEWA 5DFJA 3NR8A 2A40B 4AWNA 2F1NA 2XSWA 2V0SA 2ISIA 2A41B 1DE9A 3DNIA 5INPA 1DNKA 3G1KA 3G00A 2F2FB 1AKOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SR4 B;  4GZ0 A;  5CFE A;  3W2Y A;  4QH9 A;  5DFI A;  4A9C A;  3K55 A;  1NTF A;  5J3S A;  2DDS A;  3G38 A;  3FZI A;  3G8V A;  3NGQ A;  1DE8 A;  1I9Z A;  2A42 B;  2O3C A;  3G4T A;  4JG3 A;  4F1R A;  4F1H B;  3CJC D;  4QHE A;  3G3Y A;  1E9N A;  2IMQ X;  3G2C A;  5HT2 A;  3I5V A;  2V0R A;  5DV4 A;  2A3Z B;  2O3H A;  4L1Y A;  1ZWX A;  2JC5 A;  3GA6 A;  1Y21 A;  5A7I A;  3W3D B;  3NGO A;  4LND A;  4GZ2 A;  2DDT A;  5INM A;  2EI9 A;  3MPR A;  5DV2 A;  1BIX A;  2JC4 A;  1ATN D;  3G91 A;  4K6L F;  3N9V A;  4PUQ A;  5J42 A;  2J63 A;  1YJH A;  2DNJ A;  1WDU A;  4GYZ A;  3I48 A;  4CMN A;  4L20 A;  4L1Z A;  5INL A;  1DEW A;  2UYR X;  5CFG A;  4RUW A;  4IEM A;  4F1H A;  3I46 A;  5J3Z A;  5INQ A;  5INN A;  2VOA A;  2DDR A;  3MTC A;  3G3C A;  5INO A;  5DFH A;  4QHD A;  3NGN A;  1VYB A;  3WCX A;  3TEB A;  3G2D A;  4FPV A;  1SI6 X;  1HD7 A;  4GZ1 A;  4F1I A;  5INK A;  3U8U A;  3G0A A;  5A7J A;  5J3P A;  3L1W A;  4B5M A;  4FVA A;  4B5H A;  1I9Y A;  5EWT A;  3G0R A;  3G6S A;  4B5F A;  4L21 A;  4CML A;  5J8N A;  2D1K B;  4B5I A;  5DG0 A;  4B5G A;  4B5J A;  4C1R A;  3I41 A;  5DFF A;  3W2X A;  4GEW A;  5DFJ A;  3NR8 A;  2A40 B;  4AWN A;  2F1N A;  2XSW A;  2V0S A;  2ISI A;  2A41 B;  1DE9 A;  3DNI A;  5INP A;  1DNK A;  3G1K A;  3G00 A;  2F2F B;  1AKO A; 
#chains in the Genus database with same CATH topology
 1SR4 B;  4GZ0 A;  5CFE A;  3W2Y A;  4QH9 A;  5DFI A;  4A9C A;  3K55 A;  1NTF A;  5J3S A;  2DDS A;  3G38 A;  3FZI A;  3G8V A;  3NGQ A;  1DE8 A;  1I9Z A;  2A42 B;  2O3C A;  3G4T A;  4JG3 A;  4F1R A;  4F1H B;  3CJC D;  4QHE A;  3G3Y A;  1E9N A;  2IMQ X;  3G2C A;  5HT2 A;  3I5V A;  2V0R A;  5DV4 A;  2A3Z B;  2O3H A;  4L1Y A;  1ZWX A;  2JC5 A;  3GA6 A;  1Y21 A;  5A7I A;  3W3D B;  3NGO A;  4LND A;  4GZ2 A;  2DDT A;  5INM A;  2EI9 A;  3MPR A;  5DV2 A;  1BIX A;  2JC4 A;  1ATN D;  3G91 A;  4K6L F;  3N9V A;  4PUQ A;  5J42 A;  2J63 A;  1YJH A;  2DNJ A;  1WDU A;  4GYZ A;  3I48 A;  4CMN A;  4L20 A;  4L1Z A;  5INL A;  1DEW A;  2UYR X;  5CFG A;  4RUW A;  4IEM A;  4F1H A;  3I46 A;  5J3Z A;  5INQ A;  5INN A;  2VOA A;  2DDR A;  3MTC A;  3G3C A;  5INO A;  5DFH A;  4QHD A;  3NGN A;  1VYB A;  3WCX A;  3TEB A;  3G2D A;  4FPV A;  1SI6 X;  1HD7 A;  4GZ1 A;  4F1I A;  5INK A;  3U8U A;  3G0A A;  5A7J A;  5J3P A;  3L1W A;  4B5M A;  4FVA A;  4B5H A;  1I9Y A;  5EWT A;  3G0R A;  3G6S A;  4B5F A;  4L21 A;  4CML A;  5J8N A;  2D1K B;  4B5I A;  5DG0 A;  4B5G A;  4B5J A;  4C1R A;  3I41 A;  5DFF A;  3W2X A;  4GEW A;  5DFJ A;  3NR8 A;  2A40 B;  4AWN A;  2F1N A;  2XSW A;  2V0S A;  2ISI A;  2A41 B;  1DE9 A;  3DNI A;  5INP A;  1DNK A;  3G1K A;  3G00 A;  2F2F B;  1AKO A; 
#chains in the Genus database with same CATH homology
 1SR4 B;  4GZ0 A;  5CFE A;  3W2Y A;  4QH9 A;  5DFI A;  4A9C A;  3K55 A;  1NTF A;  5J3S A;  2DDS A;  3G38 A;  3FZI A;  3G8V A;  3NGQ A;  1DE8 A;  1I9Z A;  2A42 B;  2O3C A;  3G4T A;  4JG3 A;  4F1R A;  4F1H B;  3CJC D;  4QHE A;  3G3Y A;  1E9N A;  2IMQ X;  3G2C A;  5HT2 A;  3I5V A;  2V0R A;  5DV4 A;  2A3Z B;  2O3H A;  4L1Y A;  1ZWX A;  2JC5 A;  3GA6 A;  1Y21 A;  5A7I A;  3W3D B;  3NGO A;  4LND A;  4GZ2 A;  2DDT A;  5INM A;  2EI9 A;  3MPR A;  5DV2 A;  1BIX A;  2JC4 A;  1ATN D;  3G91 A;  4K6L F;  3N9V A;  4PUQ A;  5J42 A;  2J63 A;  1YJH A;  2DNJ A;  1WDU A;  4GYZ A;  3I48 A;  4CMN A;  4L20 A;  4L1Z A;  5INL A;  1DEW A;  2UYR X;  5CFG A;  4RUW A;  4IEM A;  4F1H A;  3I46 A;  5J3Z A;  5INQ A;  5INN A;  2VOA A;  2DDR A;  3MTC A;  3G3C A;  5INO A;  5DFH A;  4QHD A;  3NGN A;  1VYB A;  3WCX A;  3TEB A;  3G2D A;  4FPV A;  1SI6 X;  1HD7 A;  4GZ1 A;  4F1I A;  5INK A;  3U8U A;  3G0A A;  5A7J A;  5J3P A;  3L1W A;  4B5M A;  4FVA A;  4B5H A;  1I9Y A;  5EWT A;  3G0R A;  3G6S A;  4B5F A;  4L21 A;  4CML A;  5J8N A;  2D1K B;  4B5I A;  5DG0 A;  4B5G A;  4B5J A;  4C1R A;  3I41 A;  5DFF A;  3W2X A;  4GEW A;  5DFJ A;  3NR8 A;  2A40 B;  4AWN A;  2F1N A;  2XSW A;  2V0S A;  2ISI A;  2A41 B;  1DE9 A;  3DNI A;  5INP A;  1DNK A;  3G1K A;  3G00 A;  2F2F B;  1AKO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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