4FVAA

Crystal structure of truncated caenorhabditis elegans tdp2
Total Genus 81
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
249
structure length
249
Chain Sequence
DLKGFEVSVMSWNIDGLDGRSLLTRMKAVAHIVKNVNPDILFLQEVVDRDLAPIDKLQSLYKIYYSNKGCQYYTAILVSKMFDVEKHDVIHFQNSGMYRTLQILEGSIGGLKVFLLNTHLESTREHRPQRCAQFGFCMDKVREIIAQNPGALVFFGGDLNLRDEEVSRVPDGVKDAWEAAGSDNKTKFTWDTFKNDNKQGFHGAKMRFDRLYWSGPLDKVKFTLEGRQRIRSCLCFPSDHWAINATFFA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2.
pubmed doi rcsb
molecule tags Hydrolase
source organism Caenorhabditis elegans
molecule keywords 5'-tyrosyl-DNA phosphodiesterase
total genus 81
structure length 249
sequence length 249
chains with identical sequence B, C, D
ec nomenclature ec 3.1.4.-:
pdb deposition date 2012-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 4fvaA00
5CFGA 3U8UA 5DFIA 4F1IA 4GZ0A 3I46A 5J8NA 5INQA 2DDRA 5DFJA 3G4TA 4L1ZA 4IEMA 3G8VA 5INLA 3G38A 3W3DB 3NGNA 5DG0A 4L20A 4QHDA 3NR8A 2J63A 1I9YA 3G3CA 5EWTA 4GZ1A 5HT2A 2O3HA 5DV4A 1ATND 1NTFA 4LNDA 4B5FA 2D1KB 3DNIA 1HD7A 2IMQX 3I48A 5INMA 3G0AA 4FVAA 3W2YA 4CMLA 3G6SA 2A41B 4F1HA 3NGOA 2EI9A 5DFFA 2JC4A 3GA6A 4JG3A 4GZ2A 3I5VA 4B5JA 4F1RA 1DEWA 1ZWXA 4CMNA 5INPA 1DE8A 1DE9A 4PUQA 4QHEA 3G2DA 3G3YA 2ISIA 5INKA 3FZIA 4QH9A 5INNA 4B5MA 3G91A 1BIXA 2XSWA 2A42B 3G1KA 2O3CA 1E9NA 1YJHA 5INOA 5DV2A 3G00A 5DFHA 1SI6X 1Y21A 3CJCD 5J3ZA 5A7IA 3TEBA 2F2FB 1I9ZA 4B5HA 2V0SA 2V0RA 5J3SA 4C1RA 1VYBA 1SR4B 3K55A 5J3PA 3MPRA 5CFEA 4L21A 2F1NA 1DNKA 3L1WA 3N9VA 2DDSA 4GYZA 3G2CA 4AWNA 2JC5A 1AKOA 3NGQA 4A9CA 5J42A 4RUWA 3WCXA 4FPVA 2A3ZB 4F1HB 5A7JA 3W2XA 3MTCA 2A40B 4K6LF 1WDUA 4L1YA 2DNJA 2DDTA 4GEWA 3I41A 2UYRX 4B5GA 4B5IA 2VOAA 3G0RA
chains in the Genus database with same CATH superfamily
5CFGA 3U8UA 5DFIA 4F1IA 4GZ0A 3I46A 5J8NA 5INQA 2DDRA 5DFJA 3G4TA 4L1ZA 4IEMA 3G8VA 5INLA 3G38A 3W3DB 3NGNA 5DG0A 4L20A 4QHDA 3NR8A 2J63A 1I9YA 3G3CA 5EWTA 4GZ1A 5HT2A 2O3HA 5DV4A 1ATND 1NTFA 4LNDA 4B5FA 2D1KB 3DNIA 1HD7A 2IMQX 3I48A 5INMA 3G0AA 4FVAA 3W2YA 4CMLA 3G6SA 2A41B 4F1HA 3NGOA 2EI9A 5DFFA 2JC4A 3GA6A 4JG3A 4GZ2A 3I5VA 4B5JA 4F1RA 1DEWA 1ZWXA 4CMNA 5INPA 1DE8A 1DE9A 4PUQA 4QHEA 3G2DA 3G3YA 2ISIA 5INKA 3FZIA 4QH9A 5INNA 4B5MA 3G91A 1BIXA 2XSWA 2A42B 3G1KA 2O3CA 1E9NA 1YJHA 5INOA 5DV2A 3G00A 5DFHA 1SI6X 1Y21A 3CJCD 5J3ZA 5A7IA 3TEBA 2F2FB 1I9ZA 4B5HA 2V0SA 2V0RA 5J3SA 4C1RA 1VYBA 1SR4B 3K55A 5J3PA 3MPRA 5CFEA 4L21A 2F1NA 1DNKA 3L1WA 3N9VA 2DDSA 4GYZA 3G2CA 4AWNA 2JC5A 1AKOA 3NGQA 4A9CA 5J42A 4RUWA 3WCXA 4FPVA 2A3ZB 4F1HB 5A7JA 3W2XA 3MTCA 2A40B 4K6LF 1WDUA 4L1YA 2DNJA 2DDTA 4GEWA 3I41A 2UYRX 4B5GA 4B5IA 2VOAA 3G0RA
chains in the Genus database with same CATH topology
5CFGA 3U8UA 5DFIA 4F1IA 4GZ0A 3I46A 5J8NA 5INQA 2DDRA 5DFJA 3G4TA 4L1ZA 4IEMA 3G8VA 5INLA 3G38A 3W3DB 3NGNA 5DG0A 4L20A 4QHDA 3NR8A 2J63A 1I9YA 3G3CA 5EWTA 4GZ1A 5HT2A 2O3HA 5DV4A 1ATND 1NTFA 4LNDA 4B5FA 2D1KB 3DNIA 1HD7A 2IMQX 3I48A 5INMA 3G0AA 4FVAA 3W2YA 4CMLA 3G6SA 2A41B 4F1HA 3NGOA 2EI9A 5DFFA 2JC4A 3GA6A 4JG3A 4GZ2A 3I5VA 4B5JA 4F1RA 1DEWA 1ZWXA 4CMNA 5INPA 1DE8A 1DE9A 4PUQA 4QHEA 3G2DA 3G3YA 2ISIA 5INKA 3FZIA 4QH9A 5INNA 4B5MA 3G91A 1BIXA 2XSWA 2A42B 3G1KA 2O3CA 1E9NA 1YJHA 5INOA 5DV2A 3G00A 5DFHA 1SI6X 1Y21A 3CJCD 5J3ZA 5A7IA 3TEBA 2F2FB 1I9ZA 4B5HA 2V0SA 2V0RA 5J3SA 4C1RA 1VYBA 1SR4B 3K55A 5J3PA 3MPRA 5CFEA 4L21A 2F1NA 1DNKA 3L1WA 3N9VA 2DDSA 4GYZA 3G2CA 4AWNA 2JC5A 1AKOA 3NGQA 4A9CA 5J42A 4RUWA 3WCXA 4FPVA 2A3ZB 4F1HB 5A7JA 3W2XA 3MTCA 2A40B 4K6LF 1WDUA 4L1YA 2DNJA 2DDTA 4GEWA 3I41A 2UYRX 4B5GA 4B5IA 2VOAA 3G0RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5CFG A;  3U8U A;  5DFI A;  4F1I A;  4GZ0 A;  3I46 A;  5J8N A;  5INQ A;  2DDR A;  5DFJ A;  3G4T A;  4L1Z A;  4IEM A;  3G8V A;  5INL A;  3G38 A;  3W3D B;  3NGN A;  5DG0 A;  4L20 A;  4QHD A;  3NR8 A;  2J63 A;  1I9Y A;  3G3C A;  5EWT A;  4GZ1 A;  5HT2 A;  2O3H A;  5DV4 A;  1ATN D;  1NTF A;  4LND A;  4B5F A;  2D1K B;  3DNI A;  1HD7 A;  2IMQ X;  3I48 A;  5INM A;  3G0A A;  4FVA A;  3W2Y A;  4CML A;  3G6S A;  2A41 B;  4F1H A;  3NGO A;  2EI9 A;  5DFF A;  2JC4 A;  3GA6 A;  4JG3 A;  4GZ2 A;  3I5V A;  4B5J A;  4F1R A;  1DEW A;  1ZWX A;  4CMN A;  5INP A;  1DE8 A;  1DE9 A;  4PUQ A;  4QHE A;  3G2D A;  3G3Y A;  2ISI A;  5INK A;  3FZI A;  4QH9 A;  5INN A;  4B5M A;  3G91 A;  1BIX A;  2XSW A;  2A42 B;  3G1K A;  2O3C A;  1E9N A;  1YJH A;  5INO A;  5DV2 A;  3G00 A;  5DFH A;  1SI6 X;  1Y21 A;  3CJC D;  5J3Z A;  5A7I A;  3TEB A;  2F2F B;  1I9Z A;  4B5H A;  2V0S A;  2V0R A;  5J3S A;  4C1R A;  1VYB A;  1SR4 B;  3K55 A;  5J3P A;  3MPR A;  5CFE A;  4L21 A;  2F1N A;  1DNK A;  3L1W A;  3N9V A;  2DDS A;  4GYZ A;  3G2C A;  4AWN A;  2JC5 A;  1AKO A;  3NGQ A;  4A9C A;  5J42 A;  4RUW A;  3WCX A;  4FPV A;  2A3Z B;  4F1H B;  5A7J A;  3W2X A;  3MTC A;  2A40 B;  4K6L F;  1WDU A;  4L1Y A;  2DNJ A;  2DDT A;  4GEW A;  3I41 A;  2UYR X;  4B5G A;  4B5I A;  2VOA A;  3G0R A; 
#chains in the Genus database with same CATH topology
 5CFG A;  3U8U A;  5DFI A;  4F1I A;  4GZ0 A;  3I46 A;  5J8N A;  5INQ A;  2DDR A;  5DFJ A;  3G4T A;  4L1Z A;  4IEM A;  3G8V A;  5INL A;  3G38 A;  3W3D B;  3NGN A;  5DG0 A;  4L20 A;  4QHD A;  3NR8 A;  2J63 A;  1I9Y A;  3G3C A;  5EWT A;  4GZ1 A;  5HT2 A;  2O3H A;  5DV4 A;  1ATN D;  1NTF A;  4LND A;  4B5F A;  2D1K B;  3DNI A;  1HD7 A;  2IMQ X;  3I48 A;  5INM A;  3G0A A;  4FVA A;  3W2Y A;  4CML A;  3G6S A;  2A41 B;  4F1H A;  3NGO A;  2EI9 A;  5DFF A;  2JC4 A;  3GA6 A;  4JG3 A;  4GZ2 A;  3I5V A;  4B5J A;  4F1R A;  1DEW A;  1ZWX A;  4CMN A;  5INP A;  1DE8 A;  1DE9 A;  4PUQ A;  4QHE A;  3G2D A;  3G3Y A;  2ISI A;  5INK A;  3FZI A;  4QH9 A;  5INN A;  4B5M A;  3G91 A;  1BIX A;  2XSW A;  2A42 B;  3G1K A;  2O3C A;  1E9N A;  1YJH A;  5INO A;  5DV2 A;  3G00 A;  5DFH A;  1SI6 X;  1Y21 A;  3CJC D;  5J3Z A;  5A7I A;  3TEB A;  2F2F B;  1I9Z A;  4B5H A;  2V0S A;  2V0R A;  5J3S A;  4C1R A;  1VYB A;  1SR4 B;  3K55 A;  5J3P A;  3MPR A;  5CFE A;  4L21 A;  2F1N A;  1DNK A;  3L1W A;  3N9V A;  2DDS A;  4GYZ A;  3G2C A;  4AWN A;  2JC5 A;  1AKO A;  3NGQ A;  4A9C A;  5J42 A;  4RUW A;  3WCX A;  4FPV A;  2A3Z B;  4F1H B;  5A7J A;  3W2X A;  3MTC A;  2A40 B;  4K6L F;  1WDU A;  4L1Y A;  2DNJ A;  2DDT A;  4GEW A;  3I41 A;  2UYR X;  4B5G A;  4B5I A;  2VOA A;  3G0R A; 
#chains in the Genus database with same CATH homology
 5CFG A;  3U8U A;  5DFI A;  4F1I A;  4GZ0 A;  3I46 A;  5J8N A;  5INQ A;  2DDR A;  5DFJ A;  3G4T A;  4L1Z A;  4IEM A;  3G8V A;  5INL A;  3G38 A;  3W3D B;  3NGN A;  5DG0 A;  4L20 A;  4QHD A;  3NR8 A;  2J63 A;  1I9Y A;  3G3C A;  5EWT A;  4GZ1 A;  5HT2 A;  2O3H A;  5DV4 A;  1ATN D;  1NTF A;  4LND A;  4B5F A;  2D1K B;  3DNI A;  1HD7 A;  2IMQ X;  3I48 A;  5INM A;  3G0A A;  4FVA A;  3W2Y A;  4CML A;  3G6S A;  2A41 B;  4F1H A;  3NGO A;  2EI9 A;  5DFF A;  2JC4 A;  3GA6 A;  4JG3 A;  4GZ2 A;  3I5V A;  4B5J A;  4F1R A;  1DEW A;  1ZWX A;  4CMN A;  5INP A;  1DE8 A;  1DE9 A;  4PUQ A;  4QHE A;  3G2D A;  3G3Y A;  2ISI A;  5INK A;  3FZI A;  4QH9 A;  5INN A;  4B5M A;  3G91 A;  1BIX A;  2XSW A;  2A42 B;  3G1K A;  2O3C A;  1E9N A;  1YJH A;  5INO A;  5DV2 A;  3G00 A;  5DFH A;  1SI6 X;  1Y21 A;  3CJC D;  5J3Z A;  5A7I A;  3TEB A;  2F2F B;  1I9Z A;  4B5H A;  2V0S A;  2V0R A;  5J3S A;  4C1R A;  1VYB A;  1SR4 B;  3K55 A;  5J3P A;  3MPR A;  5CFE A;  4L21 A;  2F1N A;  1DNK A;  3L1W A;  3N9V A;  2DDS A;  4GYZ A;  3G2C A;  4AWN A;  2JC5 A;  1AKO A;  3NGQ A;  4A9C A;  5J42 A;  4RUW A;  3WCX A;  4FPV A;  2A3Z B;  4F1H B;  5A7J A;  3W2X A;  3MTC A;  2A40 B;  4K6L F;  1WDU A;  4L1Y A;  2DNJ A;  2DDT A;  4GEW A;  3I41 A;  2UYR X;  4B5G A;  4B5I A;  2VOA A;  3G0R A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...