4B5FA

Substrate bound neisseria ap endonuclease in absence of metal ions (crystal form 1)
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
256
structure length
256
Chain Sequence
MLKIISANVNGIRSAYKKGFYEYIAASGADIVCVQELKAQEADLSADMKNPHGMHGHWHCAEKRGYSGVAVYSKRKPDNVQIGMGIEEFDREGRFVRCDFGRLSVISLYLPSGSSAEERQQVKYRFLDAFYPMLEAMKNEGRDIVVCGDWNIAHQNIDLKNWKGNQKNSGFLPEEREWIGKVIHKLGWTDMWRTLYPDVPGYTWWSNRGQAYAKDVGWRIDYQMVTPELAAKAVSAHVYKDEKFSDHAPLVVEYDY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Neisseria meningitidis
molecule keywords PUTATIVE EXODEOXYRIBONUCLEASE
total genus 88
structure length 256
sequence length 256
ec nomenclature ec 3.1.11.2: Exodeoxyribonuclease III.
pdb deposition date 2012-08-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 4b5fA00
4FVAA 3L1WA 4L20A 5CFGA 5DFHA 5J3PA 5DFIA 4B5FA 4B5HA 5EWTA 2ISIA 5HT2A 2IMQX 2O3CA 3FZIA 3G0RA 3CJCD 5INQA 3NGOA 5DG0A 4CMNA 2DDTA 2V0SA 3G0AA 1SR4B 4FPVA 4F1HA 2XSWA 3MTCA 3G2DA 2DDRA 3W2YA 1ATND 4QHEA 4B5JA 3NGQA 4B5IA 3W2XA 4A9CA 2DNJA 3G00A 2J63A 1DEWA 1DNKA 4GZ0A 4CMLA 3G38A 4F1IA 4PUQA 3G3YA 1E9NA 1YJHA 1HD7A 3G6SA 5INLA 4LNDA 5INPA 2A40B 2JC4A 1Y21A 1WDUA 5J42A 5A7JA 2DDSA 4L21A 2A41B 1NTFA 4GZ1A 4QHDA 3G4TA 5INOA 2V0RA 3WCXA 4GEWA 2D1KB 3G2CA 5DFJA 4QH9A 3G91A 5DV4A 3GA6A 1BIXA 5DV2A 5J3ZA 5CFEA 3I41A 4AWNA 1DE9A 3I46A 3W3DB 3G1KA 5J8NA 3TEBA 4IEMA 5A7IA 3K55A 2F2FB 3I48A 2A3ZB 3N9VA 4GZ2A 4F1RA 4RUWA 3NGNA 1I9YA 3G8VA 1AKOA 1ZWXA 4B5GA 3NR8A 3G3CA 2VOAA 3U8UA 4GYZA 4C1RA 5INKA 5INMA 2UYRX 2JC5A 1I9ZA 3DNIA 5INNA 4L1YA 1VYBA 1SI6X 2O3HA 1DE8A 3MPRA 3I5VA 4L1ZA 4F1HB 2F1NA 4B5MA 4JG3A 4K6LF 5J3SA 2EI9A 2A42B 5DFFA
chains in the Genus database with same CATH superfamily
4FVAA 3L1WA 4L20A 5CFGA 5DFHA 5J3PA 5DFIA 4B5FA 4B5HA 5EWTA 2ISIA 5HT2A 2IMQX 2O3CA 3FZIA 3G0RA 3CJCD 5INQA 3NGOA 5DG0A 4CMNA 2DDTA 2V0SA 3G0AA 1SR4B 4FPVA 4F1HA 2XSWA 3MTCA 3G2DA 2DDRA 3W2YA 1ATND 4QHEA 4B5JA 3NGQA 4B5IA 3W2XA 4A9CA 2DNJA 3G00A 2J63A 1DEWA 1DNKA 4GZ0A 4CMLA 3G38A 4F1IA 4PUQA 3G3YA 1E9NA 1YJHA 1HD7A 3G6SA 5INLA 4LNDA 5INPA 2A40B 2JC4A 1Y21A 1WDUA 5J42A 5A7JA 2DDSA 4L21A 2A41B 1NTFA 4GZ1A 4QHDA 3G4TA 5INOA 2V0RA 3WCXA 4GEWA 2D1KB 3G2CA 5DFJA 4QH9A 3G91A 5DV4A 3GA6A 1BIXA 5DV2A 5J3ZA 5CFEA 3I41A 4AWNA 1DE9A 3I46A 3W3DB 3G1KA 5J8NA 3TEBA 4IEMA 5A7IA 3K55A 2F2FB 3I48A 2A3ZB 3N9VA 4GZ2A 4F1RA 4RUWA 3NGNA 1I9YA 3G8VA 1AKOA 1ZWXA 4B5GA 3NR8A 3G3CA 2VOAA 3U8UA 4GYZA 4C1RA 5INKA 5INMA 2UYRX 2JC5A 1I9ZA 3DNIA 5INNA 4L1YA 1VYBA 1SI6X 2O3HA 1DE8A 3MPRA 3I5VA 4L1ZA 4F1HB 2F1NA 4B5MA 4JG3A 4K6LF 5J3SA 2EI9A 2A42B 5DFFA
chains in the Genus database with same CATH topology
4FVAA 3L1WA 4L20A 5CFGA 5DFHA 5J3PA 5DFIA 4B5FA 4B5HA 5EWTA 2ISIA 5HT2A 2IMQX 2O3CA 3FZIA 3G0RA 3CJCD 5INQA 3NGOA 5DG0A 4CMNA 2DDTA 2V0SA 3G0AA 1SR4B 4FPVA 4F1HA 2XSWA 3MTCA 3G2DA 2DDRA 3W2YA 1ATND 4QHEA 4B5JA 3NGQA 4B5IA 3W2XA 4A9CA 2DNJA 3G00A 2J63A 1DEWA 1DNKA 4GZ0A 4CMLA 3G38A 4F1IA 4PUQA 3G3YA 1E9NA 1YJHA 1HD7A 3G6SA 5INLA 4LNDA 5INPA 2A40B 2JC4A 1Y21A 1WDUA 5J42A 5A7JA 2DDSA 4L21A 2A41B 1NTFA 4GZ1A 4QHDA 3G4TA 5INOA 2V0RA 3WCXA 4GEWA 2D1KB 3G2CA 5DFJA 4QH9A 3G91A 5DV4A 3GA6A 1BIXA 5DV2A 5J3ZA 5CFEA 3I41A 4AWNA 1DE9A 3I46A 3W3DB 3G1KA 5J8NA 3TEBA 4IEMA 5A7IA 3K55A 2F2FB 3I48A 2A3ZB 3N9VA 4GZ2A 4F1RA 4RUWA 3NGNA 1I9YA 3G8VA 1AKOA 1ZWXA 4B5GA 3NR8A 3G3CA 2VOAA 3U8UA 4GYZA 4C1RA 5INKA 5INMA 2UYRX 2JC5A 1I9ZA 3DNIA 5INNA 4L1YA 1VYBA 1SI6X 2O3HA 1DE8A 3MPRA 3I5VA 4L1ZA 4F1HB 2F1NA 4B5MA 4JG3A 4K6LF 5J3SA 2EI9A 2A42B 5DFFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FVA A;  3L1W A;  4L20 A;  5CFG A;  5DFH A;  5J3P A;  5DFI A;  4B5F A;  4B5H A;  5EWT A;  2ISI A;  5HT2 A;  2IMQ X;  2O3C A;  3FZI A;  3G0R A;  3CJC D;  5INQ A;  3NGO A;  5DG0 A;  4CMN A;  2DDT A;  2V0S A;  3G0A A;  1SR4 B;  4FPV A;  4F1H A;  2XSW A;  3MTC A;  3G2D A;  2DDR A;  3W2Y A;  1ATN D;  4QHE A;  4B5J A;  3NGQ A;  4B5I A;  3W2X A;  4A9C A;  2DNJ A;  3G00 A;  2J63 A;  1DEW A;  1DNK A;  4GZ0 A;  4CML A;  3G38 A;  4F1I A;  4PUQ A;  3G3Y A;  1E9N A;  1YJH A;  1HD7 A;  3G6S A;  5INL A;  4LND A;  5INP A;  2A40 B;  2JC4 A;  1Y21 A;  1WDU A;  5J42 A;  5A7J A;  2DDS A;  4L21 A;  2A41 B;  1NTF A;  4GZ1 A;  4QHD A;  3G4T A;  5INO A;  2V0R A;  3WCX A;  4GEW A;  2D1K B;  3G2C A;  5DFJ A;  4QH9 A;  3G91 A;  5DV4 A;  3GA6 A;  1BIX A;  5DV2 A;  5J3Z A;  5CFE A;  3I41 A;  4AWN A;  1DE9 A;  3I46 A;  3W3D B;  3G1K A;  5J8N A;  3TEB A;  4IEM A;  5A7I A;  3K55 A;  2F2F B;  3I48 A;  2A3Z B;  3N9V A;  4GZ2 A;  4F1R A;  4RUW A;  3NGN A;  1I9Y A;  3G8V A;  1AKO A;  1ZWX A;  4B5G A;  3NR8 A;  3G3C A;  2VOA A;  3U8U A;  4GYZ A;  4C1R A;  5INK A;  5INM A;  2UYR X;  2JC5 A;  1I9Z A;  3DNI A;  5INN A;  4L1Y A;  1VYB A;  1SI6 X;  2O3H A;  1DE8 A;  3MPR A;  3I5V A;  4L1Z A;  4F1H B;  2F1N A;  4B5M A;  4JG3 A;  4K6L F;  5J3S A;  2EI9 A;  2A42 B;  5DFF A; 
#chains in the Genus database with same CATH topology
 4FVA A;  3L1W A;  4L20 A;  5CFG A;  5DFH A;  5J3P A;  5DFI A;  4B5F A;  4B5H A;  5EWT A;  2ISI A;  5HT2 A;  2IMQ X;  2O3C A;  3FZI A;  3G0R A;  3CJC D;  5INQ A;  3NGO A;  5DG0 A;  4CMN A;  2DDT A;  2V0S A;  3G0A A;  1SR4 B;  4FPV A;  4F1H A;  2XSW A;  3MTC A;  3G2D A;  2DDR A;  3W2Y A;  1ATN D;  4QHE A;  4B5J A;  3NGQ A;  4B5I A;  3W2X A;  4A9C A;  2DNJ A;  3G00 A;  2J63 A;  1DEW A;  1DNK A;  4GZ0 A;  4CML A;  3G38 A;  4F1I A;  4PUQ A;  3G3Y A;  1E9N A;  1YJH A;  1HD7 A;  3G6S A;  5INL A;  4LND A;  5INP A;  2A40 B;  2JC4 A;  1Y21 A;  1WDU A;  5J42 A;  5A7J A;  2DDS A;  4L21 A;  2A41 B;  1NTF A;  4GZ1 A;  4QHD A;  3G4T A;  5INO A;  2V0R A;  3WCX A;  4GEW A;  2D1K B;  3G2C A;  5DFJ A;  4QH9 A;  3G91 A;  5DV4 A;  3GA6 A;  1BIX A;  5DV2 A;  5J3Z A;  5CFE A;  3I41 A;  4AWN A;  1DE9 A;  3I46 A;  3W3D B;  3G1K A;  5J8N A;  3TEB A;  4IEM A;  5A7I A;  3K55 A;  2F2F B;  3I48 A;  2A3Z B;  3N9V A;  4GZ2 A;  4F1R A;  4RUW A;  3NGN A;  1I9Y A;  3G8V A;  1AKO A;  1ZWX A;  4B5G A;  3NR8 A;  3G3C A;  2VOA A;  3U8U A;  4GYZ A;  4C1R A;  5INK A;  5INM A;  2UYR X;  2JC5 A;  1I9Z A;  3DNI A;  5INN A;  4L1Y A;  1VYB A;  1SI6 X;  2O3H A;  1DE8 A;  3MPR A;  3I5V A;  4L1Z A;  4F1H B;  2F1N A;  4B5M A;  4JG3 A;  4K6L F;  5J3S A;  2EI9 A;  2A42 B;  5DFF A; 
#chains in the Genus database with same CATH homology
 4FVA A;  3L1W A;  4L20 A;  5CFG A;  5DFH A;  5J3P A;  5DFI A;  4B5F A;  4B5H A;  5EWT A;  2ISI A;  5HT2 A;  2IMQ X;  2O3C A;  3FZI A;  3G0R A;  3CJC D;  5INQ A;  3NGO A;  5DG0 A;  4CMN A;  2DDT A;  2V0S A;  3G0A A;  1SR4 B;  4FPV A;  4F1H A;  2XSW A;  3MTC A;  3G2D A;  2DDR A;  3W2Y A;  1ATN D;  4QHE A;  4B5J A;  3NGQ A;  4B5I A;  3W2X A;  4A9C A;  2DNJ A;  3G00 A;  2J63 A;  1DEW A;  1DNK A;  4GZ0 A;  4CML A;  3G38 A;  4F1I A;  4PUQ A;  3G3Y A;  1E9N A;  1YJH A;  1HD7 A;  3G6S A;  5INL A;  4LND A;  5INP A;  2A40 B;  2JC4 A;  1Y21 A;  1WDU A;  5J42 A;  5A7J A;  2DDS A;  4L21 A;  2A41 B;  1NTF A;  4GZ1 A;  4QHD A;  3G4T A;  5INO A;  2V0R A;  3WCX A;  4GEW A;  2D1K B;  3G2C A;  5DFJ A;  4QH9 A;  3G91 A;  5DV4 A;  3GA6 A;  1BIX A;  5DV2 A;  5J3Z A;  5CFE A;  3I41 A;  4AWN A;  1DE9 A;  3I46 A;  3W3D B;  3G1K A;  5J8N A;  3TEB A;  4IEM A;  5A7I A;  3K55 A;  2F2F B;  3I48 A;  2A3Z B;  3N9V A;  4GZ2 A;  4F1R A;  4RUW A;  3NGN A;  1I9Y A;  3G8V A;  1AKO A;  1ZWX A;  4B5G A;  3NR8 A;  3G3C A;  2VOA A;  3U8U A;  4GYZ A;  4C1R A;  5INK A;  5INM A;  2UYR X;  2JC5 A;  1I9Z A;  3DNI A;  5INN A;  4L1Y A;  1VYB A;  1SI6 X;  2O3H A;  1DE8 A;  3MPR A;  3I5V A;  4L1Z A;  4F1H B;  2F1N A;  4B5M A;  4JG3 A;  4K6L F;  5J3S A;  2EI9 A;  2A42 B;  5DFF A; 
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