4B5GA

Substrate bound neisseria ap endonuclease in absence of metal ions (crystal form 2)
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
259
structure length
259
Chain Sequence
MLKIISANVNGIRSAYKKGFYEYIAASGADIVCVQELKAQEADLSADMKNPHGMHGHWHCAEKRGYSGVAVYSKRKPDNVQIGMGIEEFDREGRFVRCDFGRLSVISLYLPSGSSAEERQQVKYRFLDAFYPMLEAMKNEGRDIVVCGDWNIAHQNIDLKNWKGNQKNSGFLPEEREWIGKVIHKLGWTDMWRTLYPDVPGYTWWSNRGQAYAKDVGWRIDYQMVTPELAAKAVSAHVYKDEKFSDHAPLVVEYDYAAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Neisseria meningitidis
molecule keywords EXODEOXYRIBONUCLEASE
total genus 82
structure length 259
sequence length 259
chains with identical sequence B, C
ec nomenclature ec 3.1.11.2: Exodeoxyribonuclease III.
pdb deposition date 2012-08-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 4b5gA00
2EI9A 2ISIA 4CMNA 5J3PA 5CFEA 4F1HB 4B5MA 3N9VA 3W2XA 3DNIA 3NGQA 4IEMA 2DNJA 1I9ZA 3WCXA 4PUQA 3G1KA 2DDRA 4L1YA 3I41A 5INNA 5A7IA 2XSWA 3G2DA 1YJHA 5HT2A 3G00A 3TEBA 4B5FA 5DFJA 4QHDA 2A42B 2A41B 4QHEA 2A40B 1WDUA 3NGOA 2O3HA 1I9YA 4FPVA 3W3DB 3GA6A 5INLA 3I5VA 2VOAA 3NR8A 5INOA 4B5JA 2F1NA 5DV2A 4CMLA 4L20A 2IMQX 1NTFA 4B5GA 1Y21A 5DFFA 4F1RA 3G0AA 4B5IA 2J63A 4AWNA 2JC5A 1ATND 3CJCD 2V0RA 2O3CA 4C1RA 4F1IA 5DV4A 5EWTA 5INQA 3MTCA 2DDSA 3NGNA 3I46A 2JC4A 4QH9A 5DFHA 3G6SA 5CFGA 5DG0A 4FVAA 4L21A 1AKOA 3K55A 1E9NA 2D1KB 4GZ1A 3I48A 4JG3A 3G4TA 3G91A 3W2YA 3MPRA 2UYRX 4GZ0A 5INPA 1DE9A 5INKA 3G0RA 4F1HA 4K6LF 4GEWA 1SI6X 4B5HA 5J3SA 3G3YA 1DE8A 4GZ2A 5DFIA 5A7JA 3G8VA 5J42A 3FZIA 3G3CA 1ZWXA 2A3ZB 3U8UA 4RUWA 2V0SA 4GYZA 4L1ZA 1SR4B 4A9CA 3G2CA 5J3ZA 3G38A 2F2FB 2DDTA 1VYBA 4LNDA 3L1WA 1DNKA 1BIXA 5J8NA 1HD7A 5INMA 1DEWA
chains in the Genus database with same CATH superfamily
2EI9A 2ISIA 4CMNA 5J3PA 5CFEA 4F1HB 4B5MA 3N9VA 3W2XA 3DNIA 3NGQA 4IEMA 2DNJA 1I9ZA 3WCXA 4PUQA 3G1KA 2DDRA 4L1YA 3I41A 5INNA 5A7IA 2XSWA 3G2DA 1YJHA 5HT2A 3G00A 3TEBA 4B5FA 5DFJA 4QHDA 2A42B 2A41B 4QHEA 2A40B 1WDUA 3NGOA 2O3HA 1I9YA 4FPVA 3W3DB 3GA6A 5INLA 3I5VA 2VOAA 3NR8A 5INOA 4B5JA 2F1NA 5DV2A 4CMLA 4L20A 2IMQX 1NTFA 4B5GA 1Y21A 5DFFA 4F1RA 3G0AA 4B5IA 2J63A 4AWNA 2JC5A 1ATND 3CJCD 2V0RA 2O3CA 4C1RA 4F1IA 5DV4A 5EWTA 5INQA 3MTCA 2DDSA 3NGNA 3I46A 2JC4A 4QH9A 5DFHA 3G6SA 5CFGA 5DG0A 4FVAA 4L21A 1AKOA 3K55A 1E9NA 2D1KB 4GZ1A 3I48A 4JG3A 3G4TA 3G91A 3W2YA 3MPRA 2UYRX 4GZ0A 5INPA 1DE9A 5INKA 3G0RA 4F1HA 4K6LF 4GEWA 1SI6X 4B5HA 5J3SA 3G3YA 1DE8A 4GZ2A 5DFIA 5A7JA 3G8VA 5J42A 3FZIA 3G3CA 1ZWXA 2A3ZB 3U8UA 4RUWA 2V0SA 4GYZA 4L1ZA 1SR4B 4A9CA 3G2CA 5J3ZA 3G38A 2F2FB 2DDTA 1VYBA 4LNDA 3L1WA 1DNKA 1BIXA 5J8NA 1HD7A 5INMA 1DEWA
chains in the Genus database with same CATH topology
2EI9A 2ISIA 4CMNA 5J3PA 5CFEA 4F1HB 4B5MA 3N9VA 3W2XA 3DNIA 3NGQA 4IEMA 2DNJA 1I9ZA 3WCXA 4PUQA 3G1KA 2DDRA 4L1YA 3I41A 5INNA 5A7IA 2XSWA 3G2DA 1YJHA 5HT2A 3G00A 3TEBA 4B5FA 5DFJA 4QHDA 2A42B 2A41B 4QHEA 2A40B 1WDUA 3NGOA 2O3HA 1I9YA 4FPVA 3W3DB 3GA6A 5INLA 3I5VA 2VOAA 3NR8A 5INOA 4B5JA 2F1NA 5DV2A 4CMLA 4L20A 2IMQX 1NTFA 4B5GA 1Y21A 5DFFA 4F1RA 3G0AA 4B5IA 2J63A 4AWNA 2JC5A 1ATND 3CJCD 2V0RA 2O3CA 4C1RA 4F1IA 5DV4A 5EWTA 5INQA 3MTCA 2DDSA 3NGNA 3I46A 2JC4A 4QH9A 5DFHA 3G6SA 5CFGA 5DG0A 4FVAA 4L21A 1AKOA 3K55A 1E9NA 2D1KB 4GZ1A 3I48A 4JG3A 3G4TA 3G91A 3W2YA 3MPRA 2UYRX 4GZ0A 5INPA 1DE9A 5INKA 3G0RA 4F1HA 4K6LF 4GEWA 1SI6X 4B5HA 5J3SA 3G3YA 1DE8A 4GZ2A 5DFIA 5A7JA 3G8VA 5J42A 3FZIA 3G3CA 1ZWXA 2A3ZB 3U8UA 4RUWA 2V0SA 4GYZA 4L1ZA 1SR4B 4A9CA 3G2CA 5J3ZA 3G38A 2F2FB 2DDTA 1VYBA 4LNDA 3L1WA 1DNKA 1BIXA 5J8NA 1HD7A 5INMA 1DEWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EI9 A;  2ISI A;  4CMN A;  5J3P A;  5CFE A;  4F1H B;  4B5M A;  3N9V A;  3W2X A;  3DNI A;  3NGQ A;  4IEM A;  2DNJ A;  1I9Z A;  3WCX A;  4PUQ A;  3G1K A;  2DDR A;  4L1Y A;  3I41 A;  5INN A;  5A7I A;  2XSW A;  3G2D A;  1YJH A;  5HT2 A;  3G00 A;  3TEB A;  4B5F A;  5DFJ A;  4QHD A;  2A42 B;  2A41 B;  4QHE A;  2A40 B;  1WDU A;  3NGO A;  2O3H A;  1I9Y A;  4FPV A;  3W3D B;  3GA6 A;  5INL A;  3I5V A;  2VOA A;  3NR8 A;  5INO A;  4B5J A;  2F1N A;  5DV2 A;  4CML A;  4L20 A;  2IMQ X;  1NTF A;  4B5G A;  1Y21 A;  5DFF A;  4F1R A;  3G0A A;  4B5I A;  2J63 A;  4AWN A;  2JC5 A;  1ATN D;  3CJC D;  2V0R A;  2O3C A;  4C1R A;  4F1I A;  5DV4 A;  5EWT A;  5INQ A;  3MTC A;  2DDS A;  3NGN A;  3I46 A;  2JC4 A;  4QH9 A;  5DFH A;  3G6S A;  5CFG A;  5DG0 A;  4FVA A;  4L21 A;  1AKO A;  3K55 A;  1E9N A;  2D1K B;  4GZ1 A;  3I48 A;  4JG3 A;  3G4T A;  3G91 A;  3W2Y A;  3MPR A;  2UYR X;  4GZ0 A;  5INP A;  1DE9 A;  5INK A;  3G0R A;  4F1H A;  4K6L F;  4GEW A;  1SI6 X;  4B5H A;  5J3S A;  3G3Y A;  1DE8 A;  4GZ2 A;  5DFI A;  5A7J A;  3G8V A;  5J42 A;  3FZI A;  3G3C A;  1ZWX A;  2A3Z B;  3U8U A;  4RUW A;  2V0S A;  4GYZ A;  4L1Z A;  1SR4 B;  4A9C A;  3G2C A;  5J3Z A;  3G38 A;  2F2F B;  2DDT A;  1VYB A;  4LND A;  3L1W A;  1DNK A;  1BIX A;  5J8N A;  1HD7 A;  5INM A;  1DEW A; 
#chains in the Genus database with same CATH topology
 2EI9 A;  2ISI A;  4CMN A;  5J3P A;  5CFE A;  4F1H B;  4B5M A;  3N9V A;  3W2X A;  3DNI A;  3NGQ A;  4IEM A;  2DNJ A;  1I9Z A;  3WCX A;  4PUQ A;  3G1K A;  2DDR A;  4L1Y A;  3I41 A;  5INN A;  5A7I A;  2XSW A;  3G2D A;  1YJH A;  5HT2 A;  3G00 A;  3TEB A;  4B5F A;  5DFJ A;  4QHD A;  2A42 B;  2A41 B;  4QHE A;  2A40 B;  1WDU A;  3NGO A;  2O3H A;  1I9Y A;  4FPV A;  3W3D B;  3GA6 A;  5INL A;  3I5V A;  2VOA A;  3NR8 A;  5INO A;  4B5J A;  2F1N A;  5DV2 A;  4CML A;  4L20 A;  2IMQ X;  1NTF A;  4B5G A;  1Y21 A;  5DFF A;  4F1R A;  3G0A A;  4B5I A;  2J63 A;  4AWN A;  2JC5 A;  1ATN D;  3CJC D;  2V0R A;  2O3C A;  4C1R A;  4F1I A;  5DV4 A;  5EWT A;  5INQ A;  3MTC A;  2DDS A;  3NGN A;  3I46 A;  2JC4 A;  4QH9 A;  5DFH A;  3G6S A;  5CFG A;  5DG0 A;  4FVA A;  4L21 A;  1AKO A;  3K55 A;  1E9N A;  2D1K B;  4GZ1 A;  3I48 A;  4JG3 A;  3G4T A;  3G91 A;  3W2Y A;  3MPR A;  2UYR X;  4GZ0 A;  5INP A;  1DE9 A;  5INK A;  3G0R A;  4F1H A;  4K6L F;  4GEW A;  1SI6 X;  4B5H A;  5J3S A;  3G3Y A;  1DE8 A;  4GZ2 A;  5DFI A;  5A7J A;  3G8V A;  5J42 A;  3FZI A;  3G3C A;  1ZWX A;  2A3Z B;  3U8U A;  4RUW A;  2V0S A;  4GYZ A;  4L1Z A;  1SR4 B;  4A9C A;  3G2C A;  5J3Z A;  3G38 A;  2F2F B;  2DDT A;  1VYB A;  4LND A;  3L1W A;  1DNK A;  1BIX A;  5J8N A;  1HD7 A;  5INM A;  1DEW A; 
#chains in the Genus database with same CATH homology
 2EI9 A;  2ISI A;  4CMN A;  5J3P A;  5CFE A;  4F1H B;  4B5M A;  3N9V A;  3W2X A;  3DNI A;  3NGQ A;  4IEM A;  2DNJ A;  1I9Z A;  3WCX A;  4PUQ A;  3G1K A;  2DDR A;  4L1Y A;  3I41 A;  5INN A;  5A7I A;  2XSW A;  3G2D A;  1YJH A;  5HT2 A;  3G00 A;  3TEB A;  4B5F A;  5DFJ A;  4QHD A;  2A42 B;  2A41 B;  4QHE A;  2A40 B;  1WDU A;  3NGO A;  2O3H A;  1I9Y A;  4FPV A;  3W3D B;  3GA6 A;  5INL A;  3I5V A;  2VOA A;  3NR8 A;  5INO A;  4B5J A;  2F1N A;  5DV2 A;  4CML A;  4L20 A;  2IMQ X;  1NTF A;  4B5G A;  1Y21 A;  5DFF A;  4F1R A;  3G0A A;  4B5I A;  2J63 A;  4AWN A;  2JC5 A;  1ATN D;  3CJC D;  2V0R A;  2O3C A;  4C1R A;  4F1I A;  5DV4 A;  5EWT A;  5INQ A;  3MTC A;  2DDS A;  3NGN A;  3I46 A;  2JC4 A;  4QH9 A;  5DFH A;  3G6S A;  5CFG A;  5DG0 A;  4FVA A;  4L21 A;  1AKO A;  3K55 A;  1E9N A;  2D1K B;  4GZ1 A;  3I48 A;  4JG3 A;  3G4T A;  3G91 A;  3W2Y A;  3MPR A;  2UYR X;  4GZ0 A;  5INP A;  1DE9 A;  5INK A;  3G0R A;  4F1H A;  4K6L F;  4GEW A;  1SI6 X;  4B5H A;  5J3S A;  3G3Y A;  1DE8 A;  4GZ2 A;  5DFI A;  5A7J A;  3G8V A;  5J42 A;  3FZI A;  3G3C A;  1ZWX A;  2A3Z B;  3U8U A;  4RUW A;  2V0S A;  4GYZ A;  4L1Z A;  1SR4 B;  4A9C A;  3G2C A;  5J3Z A;  3G38 A;  2F2F B;  2DDT A;  1VYB A;  4LND A;  3L1W A;  1DNK A;  1BIX A;  5J8N A;  1HD7 A;  5INM A;  1DEW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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