4B5JA

Neisseria ap endonuclease bound to the substrate with an orphan adenine base
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
256
structure length
256
Chain Sequence
MLKIISANVNGIRSAYKKGFYEYIAASGADIVCVQELKAQEADLSADMKNPHGMHGHWHCAEKRGYSGVAVYSKRKPDNVQIGMGIEEFDREGRFVRCDFGRLSVISLYLPSGSSAEERQQVKYRFLDAFYPMLEAMKNEGRDIVVCGDWNIAHQNIDLKNWKGNQKNSGFLPEEREWIGKVIHKLGWTDMWRTLYPDVPGYTWWSNRGQAYAKDVGWRIDYQMVTPELAAKAVSAHVYKDEKFSDHAPLVVEYDY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Neisseria meningitidis
molecule keywords PUTATIVE EXODEOXYRIBONUCLEASE
total genus 86
structure length 256
sequence length 256
ec nomenclature ec 3.1.11.2: Exodeoxyribonuclease III.
pdb deposition date 2012-08-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 4b5jA00
1YJHA 4F1IA 3I5VA 4AWNA 3MTCA 4B5HA 1VYBA 2J63A 4CMLA 5J3SA 5A7IA 2A42B 3G2CA 4GYZA 1Y21A 2O3CA 4B5IA 5INPA 5CFGA 2DDTA 2XSWA 3TEBA 2JC5A 2D1KB 1DE8A 2DDRA 3G0AA 2VOAA 4B5FA 2A3ZB 1DE9A 3GA6A 2ISIA 3I46A 3K55A 2DDSA 2F2FB 5A7JA 1AKOA 3G00A 4FPVA 3G4TA 1HD7A 5CFEA 3CJCD 5INKA 1I9YA 4A9CA 4IEMA 4L1ZA 5DFHA 4RUWA 3I48A 3W2YA 3MPRA 5INLA 5INQA 4F1HA 2V0RA 1DEWA 2F1NA 5INMA 1I9ZA 3WCXA 5J3PA 1E9NA 5DFJA 4GZ2A 1NTFA 3DNIA 3G2DA 1SI6X 3FZIA 4B5MA 3G38A 4L21A 3G91A 2UYRX 3NGOA 2O3HA 4QHDA 3I41A 4LNDA 3NGNA 3NGQA 3W3DB 3W2XA 4K6LF 2A41B 5HT2A 4PUQA 1SR4B 2A40B 2JC4A 3N9VA 5DV4A 5DFIA 5DFFA 4F1RA 4F1HB 5INOA 4QH9A 4CMNA 4GZ0A 5DG0A 2EI9A 4L20A 1ZWXA 4B5GA 3U8UA 3G3YA 5J42A 2IMQX 3G3CA 4FVAA 3G6SA 4B5JA 5EWTA 1DNKA 5J8NA 5INNA 3G1KA 3NR8A 3L1WA 4GZ1A 5DV2A 4JG3A 4GEWA 4L1YA 4C1RA 3G8VA 1WDUA 2V0SA 3G0RA 4QHEA 1ATND 5J3ZA 2DNJA 1BIXA
chains in the Genus database with same CATH superfamily
1YJHA 4F1IA 3I5VA 4AWNA 3MTCA 4B5HA 1VYBA 2J63A 4CMLA 5J3SA 5A7IA 2A42B 3G2CA 4GYZA 1Y21A 2O3CA 4B5IA 5INPA 5CFGA 2DDTA 2XSWA 3TEBA 2JC5A 2D1KB 1DE8A 2DDRA 3G0AA 2VOAA 4B5FA 2A3ZB 1DE9A 3GA6A 2ISIA 3I46A 3K55A 2DDSA 2F2FB 5A7JA 1AKOA 3G00A 4FPVA 3G4TA 1HD7A 5CFEA 3CJCD 5INKA 1I9YA 4A9CA 4IEMA 4L1ZA 5DFHA 4RUWA 3I48A 3W2YA 3MPRA 5INLA 5INQA 4F1HA 2V0RA 1DEWA 2F1NA 5INMA 1I9ZA 3WCXA 5J3PA 1E9NA 5DFJA 4GZ2A 1NTFA 3DNIA 3G2DA 1SI6X 3FZIA 4B5MA 3G38A 4L21A 3G91A 2UYRX 3NGOA 2O3HA 4QHDA 3I41A 4LNDA 3NGNA 3NGQA 3W3DB 3W2XA 4K6LF 2A41B 5HT2A 4PUQA 1SR4B 2A40B 2JC4A 3N9VA 5DV4A 5DFIA 5DFFA 4F1RA 4F1HB 5INOA 4QH9A 4CMNA 4GZ0A 5DG0A 2EI9A 4L20A 1ZWXA 4B5GA 3U8UA 3G3YA 5J42A 2IMQX 3G3CA 4FVAA 3G6SA 4B5JA 5EWTA 1DNKA 5J8NA 5INNA 3G1KA 3NR8A 3L1WA 4GZ1A 5DV2A 4JG3A 4GEWA 4L1YA 4C1RA 3G8VA 1WDUA 2V0SA 3G0RA 4QHEA 1ATND 5J3ZA 2DNJA 1BIXA
chains in the Genus database with same CATH topology
1YJHA 4F1IA 3I5VA 4AWNA 3MTCA 4B5HA 1VYBA 2J63A 4CMLA 5J3SA 5A7IA 2A42B 3G2CA 4GYZA 1Y21A 2O3CA 4B5IA 5INPA 5CFGA 2DDTA 2XSWA 3TEBA 2JC5A 2D1KB 1DE8A 2DDRA 3G0AA 2VOAA 4B5FA 2A3ZB 1DE9A 3GA6A 2ISIA 3I46A 3K55A 2DDSA 2F2FB 5A7JA 1AKOA 3G00A 4FPVA 3G4TA 1HD7A 5CFEA 3CJCD 5INKA 1I9YA 4A9CA 4IEMA 4L1ZA 5DFHA 4RUWA 3I48A 3W2YA 3MPRA 5INLA 5INQA 4F1HA 2V0RA 1DEWA 2F1NA 5INMA 1I9ZA 3WCXA 5J3PA 1E9NA 5DFJA 4GZ2A 1NTFA 3DNIA 3G2DA 1SI6X 3FZIA 4B5MA 3G38A 4L21A 3G91A 2UYRX 3NGOA 2O3HA 4QHDA 3I41A 4LNDA 3NGNA 3NGQA 3W3DB 3W2XA 4K6LF 2A41B 5HT2A 4PUQA 1SR4B 2A40B 2JC4A 3N9VA 5DV4A 5DFIA 5DFFA 4F1RA 4F1HB 5INOA 4QH9A 4CMNA 4GZ0A 5DG0A 2EI9A 4L20A 1ZWXA 4B5GA 3U8UA 3G3YA 5J42A 2IMQX 3G3CA 4FVAA 3G6SA 4B5JA 5EWTA 1DNKA 5J8NA 5INNA 3G1KA 3NR8A 3L1WA 4GZ1A 5DV2A 4JG3A 4GEWA 4L1YA 4C1RA 3G8VA 1WDUA 2V0SA 3G0RA 4QHEA 1ATND 5J3ZA 2DNJA 1BIXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YJH A;  4F1I A;  3I5V A;  4AWN A;  3MTC A;  4B5H A;  1VYB A;  2J63 A;  4CML A;  5J3S A;  5A7I A;  2A42 B;  3G2C A;  4GYZ A;  1Y21 A;  2O3C A;  4B5I A;  5INP A;  5CFG A;  2DDT A;  2XSW A;  3TEB A;  2JC5 A;  2D1K B;  1DE8 A;  2DDR A;  3G0A A;  2VOA A;  4B5F A;  2A3Z B;  1DE9 A;  3GA6 A;  2ISI A;  3I46 A;  3K55 A;  2DDS A;  2F2F B;  5A7J A;  1AKO A;  3G00 A;  4FPV A;  3G4T A;  1HD7 A;  5CFE A;  3CJC D;  5INK A;  1I9Y A;  4A9C A;  4IEM A;  4L1Z A;  5DFH A;  4RUW A;  3I48 A;  3W2Y A;  3MPR A;  5INL A;  5INQ A;  4F1H A;  2V0R A;  1DEW A;  2F1N A;  5INM A;  1I9Z A;  3WCX A;  5J3P A;  1E9N A;  5DFJ A;  4GZ2 A;  1NTF A;  3DNI A;  3G2D A;  1SI6 X;  3FZI A;  4B5M A;  3G38 A;  4L21 A;  3G91 A;  2UYR X;  3NGO A;  2O3H A;  4QHD A;  3I41 A;  4LND A;  3NGN A;  3NGQ A;  3W3D B;  3W2X A;  4K6L F;  2A41 B;  5HT2 A;  4PUQ A;  1SR4 B;  2A40 B;  2JC4 A;  3N9V A;  5DV4 A;  5DFI A;  5DFF A;  4F1R A;  4F1H B;  5INO A;  4QH9 A;  4CMN A;  4GZ0 A;  5DG0 A;  2EI9 A;  4L20 A;  1ZWX A;  4B5G A;  3U8U A;  3G3Y A;  5J42 A;  2IMQ X;  3G3C A;  4FVA A;  3G6S A;  4B5J A;  5EWT A;  1DNK A;  5J8N A;  5INN A;  3G1K A;  3NR8 A;  3L1W A;  4GZ1 A;  5DV2 A;  4JG3 A;  4GEW A;  4L1Y A;  4C1R A;  3G8V A;  1WDU A;  2V0S A;  3G0R A;  4QHE A;  1ATN D;  5J3Z A;  2DNJ A;  1BIX A; 
#chains in the Genus database with same CATH topology
 1YJH A;  4F1I A;  3I5V A;  4AWN A;  3MTC A;  4B5H A;  1VYB A;  2J63 A;  4CML A;  5J3S A;  5A7I A;  2A42 B;  3G2C A;  4GYZ A;  1Y21 A;  2O3C A;  4B5I A;  5INP A;  5CFG A;  2DDT A;  2XSW A;  3TEB A;  2JC5 A;  2D1K B;  1DE8 A;  2DDR A;  3G0A A;  2VOA A;  4B5F A;  2A3Z B;  1DE9 A;  3GA6 A;  2ISI A;  3I46 A;  3K55 A;  2DDS A;  2F2F B;  5A7J A;  1AKO A;  3G00 A;  4FPV A;  3G4T A;  1HD7 A;  5CFE A;  3CJC D;  5INK A;  1I9Y A;  4A9C A;  4IEM A;  4L1Z A;  5DFH A;  4RUW A;  3I48 A;  3W2Y A;  3MPR A;  5INL A;  5INQ A;  4F1H A;  2V0R A;  1DEW A;  2F1N A;  5INM A;  1I9Z A;  3WCX A;  5J3P A;  1E9N A;  5DFJ A;  4GZ2 A;  1NTF A;  3DNI A;  3G2D A;  1SI6 X;  3FZI A;  4B5M A;  3G38 A;  4L21 A;  3G91 A;  2UYR X;  3NGO A;  2O3H A;  4QHD A;  3I41 A;  4LND A;  3NGN A;  3NGQ A;  3W3D B;  3W2X A;  4K6L F;  2A41 B;  5HT2 A;  4PUQ A;  1SR4 B;  2A40 B;  2JC4 A;  3N9V A;  5DV4 A;  5DFI A;  5DFF A;  4F1R A;  4F1H B;  5INO A;  4QH9 A;  4CMN A;  4GZ0 A;  5DG0 A;  2EI9 A;  4L20 A;  1ZWX A;  4B5G A;  3U8U A;  3G3Y A;  5J42 A;  2IMQ X;  3G3C A;  4FVA A;  3G6S A;  4B5J A;  5EWT A;  1DNK A;  5J8N A;  5INN A;  3G1K A;  3NR8 A;  3L1W A;  4GZ1 A;  5DV2 A;  4JG3 A;  4GEW A;  4L1Y A;  4C1R A;  3G8V A;  1WDU A;  2V0S A;  3G0R A;  4QHE A;  1ATN D;  5J3Z A;  2DNJ A;  1BIX A; 
#chains in the Genus database with same CATH homology
 1YJH A;  4F1I A;  3I5V A;  4AWN A;  3MTC A;  4B5H A;  1VYB A;  2J63 A;  4CML A;  5J3S A;  5A7I A;  2A42 B;  3G2C A;  4GYZ A;  1Y21 A;  2O3C A;  4B5I A;  5INP A;  5CFG A;  2DDT A;  2XSW A;  3TEB A;  2JC5 A;  2D1K B;  1DE8 A;  2DDR A;  3G0A A;  2VOA A;  4B5F A;  2A3Z B;  1DE9 A;  3GA6 A;  2ISI A;  3I46 A;  3K55 A;  2DDS A;  2F2F B;  5A7J A;  1AKO A;  3G00 A;  4FPV A;  3G4T A;  1HD7 A;  5CFE A;  3CJC D;  5INK A;  1I9Y A;  4A9C A;  4IEM A;  4L1Z A;  5DFH A;  4RUW A;  3I48 A;  3W2Y A;  3MPR A;  5INL A;  5INQ A;  4F1H A;  2V0R A;  1DEW A;  2F1N A;  5INM A;  1I9Z A;  3WCX A;  5J3P A;  1E9N A;  5DFJ A;  4GZ2 A;  1NTF A;  3DNI A;  3G2D A;  1SI6 X;  3FZI A;  4B5M A;  3G38 A;  4L21 A;  3G91 A;  2UYR X;  3NGO A;  2O3H A;  4QHD A;  3I41 A;  4LND A;  3NGN A;  3NGQ A;  3W3D B;  3W2X A;  4K6L F;  2A41 B;  5HT2 A;  4PUQ A;  1SR4 B;  2A40 B;  2JC4 A;  3N9V A;  5DV4 A;  5DFI A;  5DFF A;  4F1R A;  4F1H B;  5INO A;  4QH9 A;  4CMN A;  4GZ0 A;  5DG0 A;  2EI9 A;  4L20 A;  1ZWX A;  4B5G A;  3U8U A;  3G3Y A;  5J42 A;  2IMQ X;  3G3C A;  4FVA A;  3G6S A;  4B5J A;  5EWT A;  1DNK A;  5J8N A;  5INN A;  3G1K A;  3NR8 A;  3L1W A;  4GZ1 A;  5DV2 A;  4JG3 A;  4GEW A;  4L1Y A;  4C1R A;  3G8V A;  1WDU A;  2V0S A;  3G0R A;  4QHE A;  1ATN D;  5J3Z A;  2DNJ A;  1BIX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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