4F1H | Genus

Total Genus 79

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	79
sequence length	250
structure length	250
Chain Sequence	DSKLSIISWNVDGLDTLNLADRARGLCSYLALYTPDVVFLQELIPAYVQYLKKRAVSYLFFEGSDDGYFTGIMLRKSRVKFLESEIICFPTTQMMRNLLIAQVTFSGQKLYLMTSHLESCKNQSQERTKQLRVVLQKIKEAPEDAIVIFAGDTNLRDAEVANVGGLPAGVCDVWEQLGKQEHCRYTWDTKANSNKTVPYVSRCRFDRIFLRSAKTAPPVTPDHMALIGMEKLDCGRYTSDHWGIYCTFNT

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Hydrolase/dna
source organism	Danio rerio
publication title	Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2. pubmed doi rcsb
molecule keywords	DNA (5'-D(PTPGPCPAP*G)-3')
total genus	79
structure length	250
sequence length	250
ec nomenclature	ec 3.1.4.-:
pdb deposition date	2012-05-06

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF03372	Exo_endo_phos	Endonuclease/Exonuclease/phosphatase family

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.60.10.10	Alpha Beta	4-Layer Sandwich	Deoxyribonuclease I; Chain A	Endonuclease/exonuclease/phosphatase	4f1hA00

3G38A 3NR8A 3I46A 3K55A 5CFEA 1I9YA 2JC5A 5EWTA 5INMA 4AWNA 1VYBA 3I5VA 4F1RA 5HT2A 1ATND 2ISIA 4B5JA 1I9ZA 3MPRA 3GA6A 4RUWA 3MTCA 4K6LF 5INOA 5DFJA 4IEMA 3CJCD 4L1YA 4B5MA 4GEWA 2XSWA 2A3ZB 1DE9A 1WDUA 5J3ZA 5DFHA 1NTFA 5DFFA 2V0SA 3L1WA 5INLA 2V0RA 5CFGA 3G0AA 3G00A 5DG0A 4GZ0A 4CMLA 3U8UA 4B5GA 4QHEA 4QHDA 2DDTA 4L20A 3W3DB 4JG3A 1DEWA 3G2CA 4L21A 2UYRX 2O3HA 1BIXA 4LNDA 2DDRA 4GYZA 4CMNA 3TEBA 3G91A 2J63A 3G1KA 4QH9A 2VOAA 3W2YA 3G2DA 3G8VA 1DE8A 4B5IA 4L1ZA 4A9CA 4F1IA 2F2FB 3DNIA 5J3PA 5DV2A 4C1RA 4FVAA 2A42B 4B5HA 1Y21A 2F1NA 3G3YA 5J8NA 4GZ1A 3W2XA 5INKA 3G4TA 1YJHA 5A7IA 3G0RA 4FPVA 2D1KB 1HD7A 3NGOA 1ZWXA 1SI6X 2EI9A 1DNKA 3G3CA 1AKOA 5J3SA 2A40B 5INQA 1SR4B 2A41B 5DV4A 5INNA 4GZ2A 2O3CA 2DDSA 4B5FA 4F1HB 3G6SA 2JC4A 2DNJA 3N9VA 3NGNA 4PUQA 5J42A 2IMQX 5DFIA 3NGQA 4F1HA 3I41A 1E9NA 3FZIA 5INPA 3WCXA 3I48A 5A7JA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 3G38 A;  3NR8 A;  3I46 A;  3K55 A;  5CFE A;  1I9Y A;  2JC5 A;  5EWT A;  5INM A;  4AWN A;  1VYB A;  3I5V A;  4F1R A;  5HT2 A;  1ATN D;  2ISI A;  4B5J A;  1I9Z A;  3MPR A;  3GA6 A;  4RUW A;  3MTC A;  4K6L F;  5INO A;  5DFJ A;  4IEM A;  3CJC D;  4L1Y A;  4B5M A;  4GEW A;  2XSW A;  2A3Z B;  1DE9 A;  1WDU A;  5J3Z A;  5DFH A;  1NTF A;  5DFF A;  2V0S A;  3L1W A;  5INL A;  2V0R A;  5CFG A;  3G0A A;  3G00 A;  5DG0 A;  4GZ0 A;  4CML A;  3U8U A;  4B5G A;  4QHE A;  4QHD A;  2DDT A;  4L20 A;  3W3D B;  4JG3 A;  1DEW A;  3G2C A;  4L21 A;  2UYR X;  2O3H A;  1BIX A;  4LND A;  2DDR A;  4GYZ A;  4CMN A;  3TEB A;  3G91 A;  2J63 A;  3G1K A;  4QH9 A;  2VOA A;  3W2Y A;  3G2D A;  3G8V A;  1DE8 A;  4B5I A;  4L1Z A;  4A9C A;  4F1I A;  2F2F B;  3DNI A;  5J3P A;  5DV2 A;  4C1R A;  4FVA A;  2A42 B;  4B5H A;  1Y21 A;  2F1N A;  3G3Y A;  5J8N A;  4GZ1 A;  3W2X A;  5INK A;  3G4T A;  1YJH A;  5A7I A;  3G0R A;  4FPV A;  2D1K B;  1HD7 A;  3NGO A;  1ZWX A;  1SI6 X;  2EI9 A;  1DNK A;  3G3C A;  1AKO A;  5J3S A;  2A40 B;  5INQ A;  1SR4 B;  2A41 B;  5DV4 A;  5INN A;  4GZ2 A;  2O3C A;  2DDS A;  4B5F A;  4F1H B;  3G6S A;  2JC4 A;  2DNJ A;  3N9V A;  3NGN A;  4PUQ A;  5J42 A;  2IMQ X;  5DFI A;  3NGQ A;  4F1H A;  3I41 A;  1E9N A;  3FZI A;  5INP A;  3WCX A;  3I48 A;  5A7J A; 
#chains in the Genus database with same CATH topology
 3G38 A;  3NR8 A;  3I46 A;  3K55 A;  5CFE A;  1I9Y A;  2JC5 A;  5EWT A;  5INM A;  4AWN A;  1VYB A;  3I5V A;  4F1R A;  5HT2 A;  1ATN D;  2ISI A;  4B5J A;  1I9Z A;  3MPR A;  3GA6 A;  4RUW A;  3MTC A;  4K6L F;  5INO A;  5DFJ A;  4IEM A;  3CJC D;  4L1Y A;  4B5M A;  4GEW A;  2XSW A;  2A3Z B;  1DE9 A;  1WDU A;  5J3Z A;  5DFH A;  1NTF A;  5DFF A;  2V0S A;  3L1W A;  5INL A;  2V0R A;  5CFG A;  3G0A A;  3G00 A;  5DG0 A;  4GZ0 A;  4CML A;  3U8U A;  4B5G A;  4QHE A;  4QHD A;  2DDT A;  4L20 A;  3W3D B;  4JG3 A;  1DEW A;  3G2C A;  4L21 A;  2UYR X;  2O3H A;  1BIX A;  4LND A;  2DDR A;  4GYZ A;  4CMN A;  3TEB A;  3G91 A;  2J63 A;  3G1K A;  4QH9 A;  2VOA A;  3W2Y A;  3G2D A;  3G8V A;  1DE8 A;  4B5I A;  4L1Z A;  4A9C A;  4F1I A;  2F2F B;  3DNI A;  5J3P A;  5DV2 A;  4C1R A;  4FVA A;  2A42 B;  4B5H A;  1Y21 A;  2F1N A;  3G3Y A;  5J8N A;  4GZ1 A;  3W2X A;  5INK A;  3G4T A;  1YJH A;  5A7I A;  3G0R A;  4FPV A;  2D1K B;  1HD7 A;  3NGO A;  1ZWX A;  1SI6 X;  2EI9 A;  1DNK A;  3G3C A;  1AKO A;  5J3S A;  2A40 B;  5INQ A;  1SR4 B;  2A41 B;  5DV4 A;  5INN A;  4GZ2 A;  2O3C A;  2DDS A;  4B5F A;  4F1H B;  3G6S A;  2JC4 A;  2DNJ A;  3N9V A;  3NGN A;  4PUQ A;  5J42 A;  2IMQ X;  5DFI A;  3NGQ A;  4F1H A;  3I41 A;  1E9N A;  3FZI A;  5INP A;  3WCX A;  3I48 A;  5A7J A; 
#chains in the Genus database with same CATH homology
 3G38 A;  3NR8 A;  3I46 A;  3K55 A;  5CFE A;  1I9Y A;  2JC5 A;  5EWT A;  5INM A;  4AWN A;  1VYB A;  3I5V A;  4F1R A;  5HT2 A;  1ATN D;  2ISI A;  4B5J A;  1I9Z A;  3MPR A;  3GA6 A;  4RUW A;  3MTC A;  4K6L F;  5INO A;  5DFJ A;  4IEM A;  3CJC D;  4L1Y A;  4B5M A;  4GEW A;  2XSW A;  2A3Z B;  1DE9 A;  1WDU A;  5J3Z A;  5DFH A;  1NTF A;  5DFF A;  2V0S A;  3L1W A;  5INL A;  2V0R A;  5CFG A;  3G0A A;  3G00 A;  5DG0 A;  4GZ0 A;  4CML A;  3U8U A;  4B5G A;  4QHE A;  4QHD A;  2DDT A;  4L20 A;  3W3D B;  4JG3 A;  1DEW A;  3G2C A;  4L21 A;  2UYR X;  2O3H A;  1BIX A;  4LND A;  2DDR A;  4GYZ A;  4CMN A;  3TEB A;  3G91 A;  2J63 A;  3G1K A;  4QH9 A;  2VOA A;  3W2Y A;  3G2D A;  3G8V A;  1DE8 A;  4B5I A;  4L1Z A;  4A9C A;  4F1I A;  2F2F B;  3DNI A;  5J3P A;  5DV2 A;  4C1R A;  4FVA A;  2A42 B;  4B5H A;  1Y21 A;  2F1N A;  3G3Y A;  5J8N A;  4GZ1 A;  3W2X A;  5INK A;  3G4T A;  1YJH A;  5A7I A;  3G0R A;  4FPV A;  2D1K B;  1HD7 A;  3NGO A;  1ZWX A;  1SI6 X;  2EI9 A;  1DNK A;  3G3C A;  1AKO A;  5J3S A;  2A40 B;  5INQ A;  1SR4 B;  2A41 B;  5DV4 A;  5INN A;  4GZ2 A;  2O3C A;  2DDS A;  4B5F A;  4F1H B;  3G6S A;  2JC4 A;  2DNJ A;  3N9V A;  3NGN A;  4PUQ A;  5J42 A;  2IMQ X;  5DFI A;  3NGQ A;  4F1H A;  3I41 A;  1E9N A;  3FZI A;  5INP A;  3WCX A;  3I48 A;  5A7J A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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4F1HA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations