4F1HB

Crystal structure of tdp2 from danio rerio complexed with a single strand dna
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
251
structure length
251
Chain Sequence
EDSKLSIISWNVDGLDTLNLADRARGLCSYLALYTPDVVFLQELIPAYVQYLKKRAVSYLFFEGSDDGYFTGIMLRKSRVKFLESEIICFPTTQMMRNLLIAQVTFSGQKLYLMTSHLESCKNQSQERTKQLRVVLQKIKEAPEDAIVIFAGDTNLRDAEVANVGGLPAGVCDVWEQLGKQEHCRYTWDTKANSNKTVPYVSRCRFDRIFLRSAKTAPPVTPDHMALIGMEKLDCGRYTSDHWGIYCTFNT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Danio rerio
molecule keywords DNA (5'-D(P*TP*GP*CP*AP*G)-3')
total genus 80
structure length 251
sequence length 251
ec nomenclature ec 3.1.4.-:
pdb deposition date 2012-05-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 4f1hB00
1I9YA 4C1RA 3I46A 1YJHA 5INNA 3L1WA 3GA6A 4F1HA 1HD7A 3W2YA 5INPA 4GZ2A 4PUQA 2DDTA 4QHDA 5HT2A 3G00A 3G3YA 5DFJA 4A9CA 2JC4A 2V0RA 4F1RA 3G3CA 2ISIA 3MTCA 5DFHA 2JC5A 3FZIA 2O3HA 1NTFA 3G2CA 5CFEA 2A41B 1BIXA 3TEBA 2A3ZB 5J3PA 4L1YA 4F1IA 5J8NA 1DEWA 3G0RA 4GEWA 3NGNA 3U8UA 4L21A 4FVAA 5CFGA 1DNKA 3G6SA 1WDUA 5DV2A 3NGOA 2UYRX 5DFIA 4B5GA 5INKA 4L20A 4FPVA 3G38A 4JG3A 1DE9A 1Y21A 5A7JA 3K55A 2DNJA 3G2DA 2DDSA 4CMNA 5EWTA 1ATND 1SR4B 4L1ZA 3N9VA 3MPRA 5DFFA 4GZ1A 2O3CA 2VOAA 4IEMA 3WCXA 4B5MA 1I9ZA 1DE8A 1ZWXA 4B5FA 2XSWA 2J63A 2V0SA 2EI9A 3I41A 3W3DB 5J3SA 3W2XA 5INLA 4QHEA 3NR8A 4AWNA 3G0AA 1SI6X 4B5IA 4B5JA 2A42B 4RUWA 3I48A 3I5VA 3G1KA 2D1KB 3CJCD 3NGQA 5DV4A 2DDRA 4K6LF 4GYZA 5DG0A 5INOA 1AKOA 5J42A 2F1NA 3DNIA 4GZ0A 5J3ZA 4CMLA 1VYBA 2IMQX 4QH9A 5INQA 5A7IA 3G91A 3G4TA 2F2FB 2A40B 5INMA 4B5HA 4LNDA 1E9NA 3G8VA 4F1HB
chains in the Genus database with same CATH superfamily
1I9YA 4C1RA 3I46A 1YJHA 5INNA 3L1WA 3GA6A 4F1HA 1HD7A 3W2YA 5INPA 4GZ2A 4PUQA 2DDTA 4QHDA 5HT2A 3G00A 3G3YA 5DFJA 4A9CA 2JC4A 2V0RA 4F1RA 3G3CA 2ISIA 3MTCA 5DFHA 2JC5A 3FZIA 2O3HA 1NTFA 3G2CA 5CFEA 2A41B 1BIXA 3TEBA 2A3ZB 5J3PA 4L1YA 4F1IA 5J8NA 1DEWA 3G0RA 4GEWA 3NGNA 3U8UA 4L21A 4FVAA 5CFGA 1DNKA 3G6SA 1WDUA 5DV2A 3NGOA 2UYRX 5DFIA 4B5GA 5INKA 4L20A 4FPVA 3G38A 4JG3A 1DE9A 1Y21A 5A7JA 3K55A 2DNJA 3G2DA 2DDSA 4CMNA 5EWTA 1ATND 1SR4B 4L1ZA 3N9VA 3MPRA 5DFFA 4GZ1A 2O3CA 2VOAA 4IEMA 3WCXA 4B5MA 1I9ZA 1DE8A 1ZWXA 4B5FA 2XSWA 2J63A 2V0SA 2EI9A 3I41A 3W3DB 5J3SA 3W2XA 5INLA 4QHEA 3NR8A 4AWNA 3G0AA 1SI6X 4B5IA 4B5JA 2A42B 4RUWA 3I48A 3I5VA 3G1KA 2D1KB 3CJCD 3NGQA 5DV4A 2DDRA 4K6LF 4GYZA 5DG0A 5INOA 1AKOA 5J42A 2F1NA 3DNIA 4GZ0A 5J3ZA 4CMLA 1VYBA 2IMQX 4QH9A 5INQA 5A7IA 3G91A 3G4TA 2F2FB 2A40B 5INMA 4B5HA 4LNDA 1E9NA 3G8VA 4F1HB
chains in the Genus database with same CATH topology
1I9YA 4C1RA 3I46A 1YJHA 5INNA 3L1WA 3GA6A 4F1HA 1HD7A 3W2YA 5INPA 4GZ2A 4PUQA 2DDTA 4QHDA 5HT2A 3G00A 3G3YA 5DFJA 4A9CA 2JC4A 2V0RA 4F1RA 3G3CA 2ISIA 3MTCA 5DFHA 2JC5A 3FZIA 2O3HA 1NTFA 3G2CA 5CFEA 2A41B 1BIXA 3TEBA 2A3ZB 5J3PA 4L1YA 4F1IA 5J8NA 1DEWA 3G0RA 4GEWA 3NGNA 3U8UA 4L21A 4FVAA 5CFGA 1DNKA 3G6SA 1WDUA 5DV2A 3NGOA 2UYRX 5DFIA 4B5GA 5INKA 4L20A 4FPVA 3G38A 4JG3A 1DE9A 1Y21A 5A7JA 3K55A 2DNJA 3G2DA 2DDSA 4CMNA 5EWTA 1ATND 1SR4B 4L1ZA 3N9VA 3MPRA 5DFFA 4GZ1A 2O3CA 2VOAA 4IEMA 3WCXA 4B5MA 1I9ZA 1DE8A 1ZWXA 4B5FA 2XSWA 2J63A 2V0SA 2EI9A 3I41A 3W3DB 5J3SA 3W2XA 5INLA 4QHEA 3NR8A 4AWNA 3G0AA 1SI6X 4B5IA 4B5JA 2A42B 4RUWA 3I48A 3I5VA 3G1KA 2D1KB 3CJCD 3NGQA 5DV4A 2DDRA 4K6LF 4GYZA 5DG0A 5INOA 1AKOA 5J42A 2F1NA 3DNIA 4GZ0A 5J3ZA 4CMLA 1VYBA 2IMQX 4QH9A 5INQA 5A7IA 3G91A 3G4TA 2F2FB 2A40B 5INMA 4B5HA 4LNDA 1E9NA 3G8VA 4F1HB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I9Y A;  4C1R A;  3I46 A;  1YJH A;  5INN A;  3L1W A;  3GA6 A;  4F1H A;  1HD7 A;  3W2Y A;  5INP A;  4GZ2 A;  4PUQ A;  2DDT A;  4QHD A;  5HT2 A;  3G00 A;  3G3Y A;  5DFJ A;  4A9C A;  2JC4 A;  2V0R A;  4F1R A;  3G3C A;  2ISI A;  3MTC A;  5DFH A;  2JC5 A;  3FZI A;  2O3H A;  1NTF A;  3G2C A;  5CFE A;  2A41 B;  1BIX A;  3TEB A;  2A3Z B;  5J3P A;  4L1Y A;  4F1I A;  5J8N A;  1DEW A;  3G0R A;  4GEW A;  3NGN A;  3U8U A;  4L21 A;  4FVA A;  5CFG A;  1DNK A;  3G6S A;  1WDU A;  5DV2 A;  3NGO A;  2UYR X;  5DFI A;  4B5G A;  5INK A;  4L20 A;  4FPV A;  3G38 A;  4JG3 A;  1DE9 A;  1Y21 A;  5A7J A;  3K55 A;  2DNJ A;  3G2D A;  2DDS A;  4CMN A;  5EWT A;  1ATN D;  1SR4 B;  4L1Z A;  3N9V A;  3MPR A;  5DFF A;  4GZ1 A;  2O3C A;  2VOA A;  4IEM A;  3WCX A;  4B5M A;  1I9Z A;  1DE8 A;  1ZWX A;  4B5F A;  2XSW A;  2J63 A;  2V0S A;  2EI9 A;  3I41 A;  3W3D B;  5J3S A;  3W2X A;  5INL A;  4QHE A;  3NR8 A;  4AWN A;  3G0A A;  1SI6 X;  4B5I A;  4B5J A;  2A42 B;  4RUW A;  3I48 A;  3I5V A;  3G1K A;  2D1K B;  3CJC D;  3NGQ A;  5DV4 A;  2DDR A;  4K6L F;  4GYZ A;  5DG0 A;  5INO A;  1AKO A;  5J42 A;  2F1N A;  3DNI A;  4GZ0 A;  5J3Z A;  4CML A;  1VYB A;  2IMQ X;  4QH9 A;  5INQ A;  5A7I A;  3G91 A;  3G4T A;  2F2F B;  2A40 B;  5INM A;  4B5H A;  4LND A;  1E9N A;  3G8V A;  4F1H B; 
#chains in the Genus database with same CATH topology
 1I9Y A;  4C1R A;  3I46 A;  1YJH A;  5INN A;  3L1W A;  3GA6 A;  4F1H A;  1HD7 A;  3W2Y A;  5INP A;  4GZ2 A;  4PUQ A;  2DDT A;  4QHD A;  5HT2 A;  3G00 A;  3G3Y A;  5DFJ A;  4A9C A;  2JC4 A;  2V0R A;  4F1R A;  3G3C A;  2ISI A;  3MTC A;  5DFH A;  2JC5 A;  3FZI A;  2O3H A;  1NTF A;  3G2C A;  5CFE A;  2A41 B;  1BIX A;  3TEB A;  2A3Z B;  5J3P A;  4L1Y A;  4F1I A;  5J8N A;  1DEW A;  3G0R A;  4GEW A;  3NGN A;  3U8U A;  4L21 A;  4FVA A;  5CFG A;  1DNK A;  3G6S A;  1WDU A;  5DV2 A;  3NGO A;  2UYR X;  5DFI A;  4B5G A;  5INK A;  4L20 A;  4FPV A;  3G38 A;  4JG3 A;  1DE9 A;  1Y21 A;  5A7J A;  3K55 A;  2DNJ A;  3G2D A;  2DDS A;  4CMN A;  5EWT A;  1ATN D;  1SR4 B;  4L1Z A;  3N9V A;  3MPR A;  5DFF A;  4GZ1 A;  2O3C A;  2VOA A;  4IEM A;  3WCX A;  4B5M A;  1I9Z A;  1DE8 A;  1ZWX A;  4B5F A;  2XSW A;  2J63 A;  2V0S A;  2EI9 A;  3I41 A;  3W3D B;  5J3S A;  3W2X A;  5INL A;  4QHE A;  3NR8 A;  4AWN A;  3G0A A;  1SI6 X;  4B5I A;  4B5J A;  2A42 B;  4RUW A;  3I48 A;  3I5V A;  3G1K A;  2D1K B;  3CJC D;  3NGQ A;  5DV4 A;  2DDR A;  4K6L F;  4GYZ A;  5DG0 A;  5INO A;  1AKO A;  5J42 A;  2F1N A;  3DNI A;  4GZ0 A;  5J3Z A;  4CML A;  1VYB A;  2IMQ X;  4QH9 A;  5INQ A;  5A7I A;  3G91 A;  3G4T A;  2F2F B;  2A40 B;  5INM A;  4B5H A;  4LND A;  1E9N A;  3G8V A;  4F1H B; 
#chains in the Genus database with same CATH homology
 1I9Y A;  4C1R A;  3I46 A;  1YJH A;  5INN A;  3L1W A;  3GA6 A;  4F1H A;  1HD7 A;  3W2Y A;  5INP A;  4GZ2 A;  4PUQ A;  2DDT A;  4QHD A;  5HT2 A;  3G00 A;  3G3Y A;  5DFJ A;  4A9C A;  2JC4 A;  2V0R A;  4F1R A;  3G3C A;  2ISI A;  3MTC A;  5DFH A;  2JC5 A;  3FZI A;  2O3H A;  1NTF A;  3G2C A;  5CFE A;  2A41 B;  1BIX A;  3TEB A;  2A3Z B;  5J3P A;  4L1Y A;  4F1I A;  5J8N A;  1DEW A;  3G0R A;  4GEW A;  3NGN A;  3U8U A;  4L21 A;  4FVA A;  5CFG A;  1DNK A;  3G6S A;  1WDU A;  5DV2 A;  3NGO A;  2UYR X;  5DFI A;  4B5G A;  5INK A;  4L20 A;  4FPV A;  3G38 A;  4JG3 A;  1DE9 A;  1Y21 A;  5A7J A;  3K55 A;  2DNJ A;  3G2D A;  2DDS A;  4CMN A;  5EWT A;  1ATN D;  1SR4 B;  4L1Z A;  3N9V A;  3MPR A;  5DFF A;  4GZ1 A;  2O3C A;  2VOA A;  4IEM A;  3WCX A;  4B5M A;  1I9Z A;  1DE8 A;  1ZWX A;  4B5F A;  2XSW A;  2J63 A;  2V0S A;  2EI9 A;  3I41 A;  3W3D B;  5J3S A;  3W2X A;  5INL A;  4QHE A;  3NR8 A;  4AWN A;  3G0A A;  1SI6 X;  4B5I A;  4B5J A;  2A42 B;  4RUW A;  3I48 A;  3I5V A;  3G1K A;  2D1K B;  3CJC D;  3NGQ A;  5DV4 A;  2DDR A;  4K6L F;  4GYZ A;  5DG0 A;  5INO A;  1AKO A;  5J42 A;  2F1N A;  3DNI A;  4GZ0 A;  5J3Z A;  4CML A;  1VYB A;  2IMQ X;  4QH9 A;  5INQ A;  5A7I A;  3G91 A;  3G4T A;  2F2F B;  2A40 B;  5INM A;  4B5H A;  4LND A;  1E9N A;  3G8V A;  4F1H B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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