5A7IA

Crystal structure of inpp5b in complex with biphenyl 3,3',4,4',5,5'- hexakisphosphate
Total Genus 89
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
313
structure length
313
Chain Sequence
MYTYIQNFRFFAGTYNVNGQSPKECLRLWLSNGIQAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPLTISNHDVILWLGDLNYRIEELDVEKVKKLIEEKDFQMLYAYDQLKIQVAAKTVFEGFTEGELTFQPTYKYDTGSDDWDTSEKCRAPAWCDRILWKGKNITQLSYQSHMALKTSDHKPVSSVFDIGVRVVAHHHHHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures of Type-II Inositol Polyphosphate 5-Phosphatase Inpp5B with Synthetic Inositol Polyphosphate Surrogates Reveal New Mechanistic Insights for the Inositol 5-Phosphatase Family.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords TYPE II INOSITOL 1,4,5-TRISPHOSPHATE 5-PHOSPHATASE
total genus 89
structure length 313
sequence length 313
ec nomenclature ec 3.1.3.36: Phosphoinositide 5-phosphatase.
pdb deposition date 2015-07-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 5a7iA00
4L1YA 2A41B 4CMLA 4RUWA 3CJCD 3NGQA 3FZIA 3W2XA 3I46A 4A9CA 3G0AA 1DE9A 1I9ZA 2VOAA 3G8VA 2A42B 3W2YA 3I48A 3G3CA 4B5GA 2D1KB 4L1ZA 3G6SA 3W3DB 2DNJA 1SI6X 5A7JA 3G0RA 1E9NA 2JC5A 1ZWXA 1ATND 2DDSA 1DEWA 3N9VA 4CMNA 2UYRX 1SR4B 1BIXA 2O3CA 2DDTA 5J3ZA 5INMA 3I5VA 5INKA 4PUQA 2XSWA 1YJHA 1NTFA 5CFEA 5J42A 2F2FB 5HT2A 3NGOA 4QHEA 4F1HB 5DG0A 3G1KA 5DFIA 5CFGA 3G2CA 4B5JA 4B5MA 3NGNA 1I9YA 5DV4A 1DE8A 4F1IA 3NR8A 3I41A 5INPA 4GYZA 4JG3A 4B5IA 4LNDA 3MTCA 4QHDA 4F1HA 1Y21A 4L20A 4B5FA 2EI9A 5INOA 3WCXA 3G38A 5A7IA 2V0SA 5INQA 4L21A 4B5HA 3G4TA 2J63A 4FPVA 4C1RA 2O3HA 5INLA 4K6LF 3U8UA 1WDUA 2F1NA 4QH9A 3MPRA 2A3ZB 1VYBA 3G3YA 5DFFA 3G2DA 4GZ2A 5INNA 5DFJA 1DNKA 2ISIA 5DV2A 4GZ0A 2IMQX 3TEBA 5DFHA 5J3PA 4GZ1A 3G00A 2JC4A 2A40B 2DDRA 2V0RA 4F1RA 5J3SA 5J8NA 3K55A 3L1WA 1AKOA 3GA6A 3G91A 4AWNA 4FVAA 1HD7A 3DNIA 4IEMA 5EWTA 4GEWA
chains in the Genus database with same CATH superfamily
4L1YA 2A41B 4CMLA 4RUWA 3CJCD 3NGQA 3FZIA 3W2XA 3I46A 4A9CA 3G0AA 1DE9A 1I9ZA 2VOAA 3G8VA 2A42B 3W2YA 3I48A 3G3CA 4B5GA 2D1KB 4L1ZA 3G6SA 3W3DB 2DNJA 1SI6X 5A7JA 3G0RA 1E9NA 2JC5A 1ZWXA 1ATND 2DDSA 1DEWA 3N9VA 4CMNA 2UYRX 1SR4B 1BIXA 2O3CA 2DDTA 5J3ZA 5INMA 3I5VA 5INKA 4PUQA 2XSWA 1YJHA 1NTFA 5CFEA 5J42A 2F2FB 5HT2A 3NGOA 4QHEA 4F1HB 5DG0A 3G1KA 5DFIA 5CFGA 3G2CA 4B5JA 4B5MA 3NGNA 1I9YA 5DV4A 1DE8A 4F1IA 3NR8A 3I41A 5INPA 4GYZA 4JG3A 4B5IA 4LNDA 3MTCA 4QHDA 4F1HA 1Y21A 4L20A 4B5FA 2EI9A 5INOA 3WCXA 3G38A 5A7IA 2V0SA 5INQA 4L21A 4B5HA 3G4TA 2J63A 4FPVA 4C1RA 2O3HA 5INLA 4K6LF 3U8UA 1WDUA 2F1NA 4QH9A 3MPRA 2A3ZB 1VYBA 3G3YA 5DFFA 3G2DA 4GZ2A 5INNA 5DFJA 1DNKA 2ISIA 5DV2A 4GZ0A 2IMQX 3TEBA 5DFHA 5J3PA 4GZ1A 3G00A 2JC4A 2A40B 2DDRA 2V0RA 4F1RA 5J3SA 5J8NA 3K55A 3L1WA 1AKOA 3GA6A 3G91A 4AWNA 4FVAA 1HD7A 3DNIA 4IEMA 5EWTA 4GEWA
chains in the Genus database with same CATH topology
4L1YA 2A41B 4CMLA 4RUWA 3CJCD 3NGQA 3FZIA 3W2XA 3I46A 4A9CA 3G0AA 1DE9A 1I9ZA 2VOAA 3G8VA 2A42B 3W2YA 3I48A 3G3CA 4B5GA 2D1KB 4L1ZA 3G6SA 3W3DB 2DNJA 1SI6X 5A7JA 3G0RA 1E9NA 2JC5A 1ZWXA 1ATND 2DDSA 1DEWA 3N9VA 4CMNA 2UYRX 1SR4B 1BIXA 2O3CA 2DDTA 5J3ZA 5INMA 3I5VA 5INKA 4PUQA 2XSWA 1YJHA 1NTFA 5CFEA 5J42A 2F2FB 5HT2A 3NGOA 4QHEA 4F1HB 5DG0A 3G1KA 5DFIA 5CFGA 3G2CA 4B5JA 4B5MA 3NGNA 1I9YA 5DV4A 1DE8A 4F1IA 3NR8A 3I41A 5INPA 4GYZA 4JG3A 4B5IA 4LNDA 3MTCA 4QHDA 4F1HA 1Y21A 4L20A 4B5FA 2EI9A 5INOA 3WCXA 3G38A 5A7IA 2V0SA 5INQA 4L21A 4B5HA 3G4TA 2J63A 4FPVA 4C1RA 2O3HA 5INLA 4K6LF 3U8UA 1WDUA 2F1NA 4QH9A 3MPRA 2A3ZB 1VYBA 3G3YA 5DFFA 3G2DA 4GZ2A 5INNA 5DFJA 1DNKA 2ISIA 5DV2A 4GZ0A 2IMQX 3TEBA 5DFHA 5J3PA 4GZ1A 3G00A 2JC4A 2A40B 2DDRA 2V0RA 4F1RA 5J3SA 5J8NA 3K55A 3L1WA 1AKOA 3GA6A 3G91A 4AWNA 4FVAA 1HD7A 3DNIA 4IEMA 5EWTA 4GEWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4L1Y A;  2A41 B;  4CML A;  4RUW A;  3CJC D;  3NGQ A;  3FZI A;  3W2X A;  3I46 A;  4A9C A;  3G0A A;  1DE9 A;  1I9Z A;  2VOA A;  3G8V A;  2A42 B;  3W2Y A;  3I48 A;  3G3C A;  4B5G A;  2D1K B;  4L1Z A;  3G6S A;  3W3D B;  2DNJ A;  1SI6 X;  5A7J A;  3G0R A;  1E9N A;  2JC5 A;  1ZWX A;  1ATN D;  2DDS A;  1DEW A;  3N9V A;  4CMN A;  2UYR X;  1SR4 B;  1BIX A;  2O3C A;  2DDT A;  5J3Z A;  5INM A;  3I5V A;  5INK A;  4PUQ A;  2XSW A;  1YJH A;  1NTF A;  5CFE A;  5J42 A;  2F2F B;  5HT2 A;  3NGO A;  4QHE A;  4F1H B;  5DG0 A;  3G1K A;  5DFI A;  5CFG A;  3G2C A;  4B5J A;  4B5M A;  3NGN A;  1I9Y A;  5DV4 A;  1DE8 A;  4F1I A;  3NR8 A;  3I41 A;  5INP A;  4GYZ A;  4JG3 A;  4B5I A;  4LND A;  3MTC A;  4QHD A;  4F1H A;  1Y21 A;  4L20 A;  4B5F A;  2EI9 A;  5INO A;  3WCX A;  3G38 A;  5A7I A;  2V0S A;  5INQ A;  4L21 A;  4B5H A;  3G4T A;  2J63 A;  4FPV A;  4C1R A;  2O3H A;  5INL A;  4K6L F;  3U8U A;  1WDU A;  2F1N A;  4QH9 A;  3MPR A;  2A3Z B;  1VYB A;  3G3Y A;  5DFF A;  3G2D A;  4GZ2 A;  5INN A;  5DFJ A;  1DNK A;  2ISI A;  5DV2 A;  4GZ0 A;  2IMQ X;  3TEB A;  5DFH A;  5J3P A;  4GZ1 A;  3G00 A;  2JC4 A;  2A40 B;  2DDR A;  2V0R A;  4F1R A;  5J3S A;  5J8N A;  3K55 A;  3L1W A;  1AKO A;  3GA6 A;  3G91 A;  4AWN A;  4FVA A;  1HD7 A;  3DNI A;  4IEM A;  5EWT A;  4GEW A; 
#chains in the Genus database with same CATH topology
 4L1Y A;  2A41 B;  4CML A;  4RUW A;  3CJC D;  3NGQ A;  3FZI A;  3W2X A;  3I46 A;  4A9C A;  3G0A A;  1DE9 A;  1I9Z A;  2VOA A;  3G8V A;  2A42 B;  3W2Y A;  3I48 A;  3G3C A;  4B5G A;  2D1K B;  4L1Z A;  3G6S A;  3W3D B;  2DNJ A;  1SI6 X;  5A7J A;  3G0R A;  1E9N A;  2JC5 A;  1ZWX A;  1ATN D;  2DDS A;  1DEW A;  3N9V A;  4CMN A;  2UYR X;  1SR4 B;  1BIX A;  2O3C A;  2DDT A;  5J3Z A;  5INM A;  3I5V A;  5INK A;  4PUQ A;  2XSW A;  1YJH A;  1NTF A;  5CFE A;  5J42 A;  2F2F B;  5HT2 A;  3NGO A;  4QHE A;  4F1H B;  5DG0 A;  3G1K A;  5DFI A;  5CFG A;  3G2C A;  4B5J A;  4B5M A;  3NGN A;  1I9Y A;  5DV4 A;  1DE8 A;  4F1I A;  3NR8 A;  3I41 A;  5INP A;  4GYZ A;  4JG3 A;  4B5I A;  4LND A;  3MTC A;  4QHD A;  4F1H A;  1Y21 A;  4L20 A;  4B5F A;  2EI9 A;  5INO A;  3WCX A;  3G38 A;  5A7I A;  2V0S A;  5INQ A;  4L21 A;  4B5H A;  3G4T A;  2J63 A;  4FPV A;  4C1R A;  2O3H A;  5INL A;  4K6L F;  3U8U A;  1WDU A;  2F1N A;  4QH9 A;  3MPR A;  2A3Z B;  1VYB A;  3G3Y A;  5DFF A;  3G2D A;  4GZ2 A;  5INN A;  5DFJ A;  1DNK A;  2ISI A;  5DV2 A;  4GZ0 A;  2IMQ X;  3TEB A;  5DFH A;  5J3P A;  4GZ1 A;  3G00 A;  2JC4 A;  2A40 B;  2DDR A;  2V0R A;  4F1R A;  5J3S A;  5J8N A;  3K55 A;  3L1W A;  1AKO A;  3GA6 A;  3G91 A;  4AWN A;  4FVA A;  1HD7 A;  3DNI A;  4IEM A;  5EWT A;  4GEW A; 
#chains in the Genus database with same CATH homology
 4L1Y A;  2A41 B;  4CML A;  4RUW A;  3CJC D;  3NGQ A;  3FZI A;  3W2X A;  3I46 A;  4A9C A;  3G0A A;  1DE9 A;  1I9Z A;  2VOA A;  3G8V A;  2A42 B;  3W2Y A;  3I48 A;  3G3C A;  4B5G A;  2D1K B;  4L1Z A;  3G6S A;  3W3D B;  2DNJ A;  1SI6 X;  5A7J A;  3G0R A;  1E9N A;  2JC5 A;  1ZWX A;  1ATN D;  2DDS A;  1DEW A;  3N9V A;  4CMN A;  2UYR X;  1SR4 B;  1BIX A;  2O3C A;  2DDT A;  5J3Z A;  5INM A;  3I5V A;  5INK A;  4PUQ A;  2XSW A;  1YJH A;  1NTF A;  5CFE A;  5J42 A;  2F2F B;  5HT2 A;  3NGO A;  4QHE A;  4F1H B;  5DG0 A;  3G1K A;  5DFI A;  5CFG A;  3G2C A;  4B5J A;  4B5M A;  3NGN A;  1I9Y A;  5DV4 A;  1DE8 A;  4F1I A;  3NR8 A;  3I41 A;  5INP A;  4GYZ A;  4JG3 A;  4B5I A;  4LND A;  3MTC A;  4QHD A;  4F1H A;  1Y21 A;  4L20 A;  4B5F A;  2EI9 A;  5INO A;  3WCX A;  3G38 A;  5A7I A;  2V0S A;  5INQ A;  4L21 A;  4B5H A;  3G4T A;  2J63 A;  4FPV A;  4C1R A;  2O3H A;  5INL A;  4K6L F;  3U8U A;  1WDU A;  2F1N A;  4QH9 A;  3MPR A;  2A3Z B;  1VYB A;  3G3Y A;  5DFF A;  3G2D A;  4GZ2 A;  5INN A;  5DFJ A;  1DNK A;  2ISI A;  5DV2 A;  4GZ0 A;  2IMQ X;  3TEB A;  5DFH A;  5J3P A;  4GZ1 A;  3G00 A;  2JC4 A;  2A40 B;  2DDR A;  2V0R A;  4F1R A;  5J3S A;  5J8N A;  3K55 A;  3L1W A;  1AKO A;  3GA6 A;  3G91 A;  4AWN A;  4FVA A;  1HD7 A;  3DNI A;  4IEM A;  5EWT A;  4GEW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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