The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
83
|
sequence length |
252
|
structure length |
252
|
Chain Sequence |
MKLISWNVNGLRAVMRKMDFLSYLKEEDADIICLQETKIQDGQVDLQPEDYHVYWNYAVKKGYSGTAVFSKQEPLQVIYGIGVEEHDQEGRVITLEFENVFVMTVYTPNSRRGLERIDYRMQWEEALLSYILELDQKKPVILCGDLNVAHQEIDLKNPKANRNNAGFSDQEREAFTRFLEAGFVDSFRHVYPDLEGAYSWWSYRAGARDRNIGWRIDYFVVSESLKEQIEDASISADVMGSDHCPVELIINI
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Structural comparison of AP endonucleases from the exonuclease III family reveals new amino acid residues in human AP endonuclease 1 that are involved in incision of damaged DNA.
pubmed doi rcsb |
| molecule tags |
Hydrolase
|
| source organism |
Bacillus subtilis (strain 168)
|
| molecule keywords |
Exodeoxyribonuclease
|
| total genus |
83
|
| structure length |
252
|
| sequence length |
252
|
| ec nomenclature |
ec
3.1.11.2: Exodeoxyribonuclease III. |
| pdb deposition date | 2015-07-08 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF03372 | Exo_endo_phos | Endonuclease/Exonuclease/phosphatase family |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | 4-Layer Sandwich | Deoxyribonuclease I; Chain A | Endonuclease/exonuclease/phosphatase |
#chains in the Genus database with same CATH superfamily 3I48 A; 3G0R A; 5A7J A; 1E9N A; 2O3H A; 1DEW A; 5J3Z A; 5INK A; 4B5I A; 3I46 A; 4GZ2 A; 2DDT A; 4GZ1 A; 3G2C A; 4JG3 A; 4LND A; 4L20 A; 5J8N A; 3K55 A; 5EWT A; 2JC4 A; 3I41 A; 3NGN A; 3FZI A; 4CML A; 5INQ A; 3DNI A; 1WDU A; 2A41 B; 5J3S A; 2A42 B; 2J63 A; 4B5H A; 5DFF A; 5CFE A; 5HT2 A; 2EI9 A; 4GZ0 A; 2XSW A; 4L21 A; 5DG0 A; 3W2Y A; 3G00 A; 4F1H B; 4FVA A; 3G8V A; 5CFG A; 2DDR A; 1VYB A; 1DE8 A; 4B5J A; 4GEW A; 2VOA A; 3G3C A; 1BIX A; 5DFH A; 5DFJ A; 1I9Z A; 5INM A; 3MPR A; 1DE9 A; 2V0S A; 5INP A; 2ISI A; 3W2X A; 2DDS A; 4RUW A; 3N9V A; 3G0A A; 3W3D B; 3G6S A; 3G91 A; 3NR8 A; 4QH9 A; 1I9Y A; 4B5F A; 4CMN A; 2D1K B; 1HD7 A; 1Y21 A; 4L1Z A; 5J3P A; 3G3Y A; 5INO A; 3G38 A; 4AWN A; 4QHE A; 2A40 B; 3G2D A; 5INL A; 3GA6 A; 4F1I A; 2IMQ X; 3G1K A; 3L1W A; 1AKO A; 3CJC D; 1SR4 B; 4IEM A; 5DFI A; 3NGO A; 4QHD A; 4B5M A; 3NGQ A; 1SI6 X; 1YJH A; 4L1Y A; 3MTC A; 3G4T A; 2F1N A; 3TEB A; 3I5V A; 5DV4 A; 2O3C A; 5J42 A; 4K6L F; 2UYR X; 1NTF A; 5DV2 A; 2DNJ A; 4FPV A; 1ZWX A; 2JC5 A; 2F2F B; 2V0R A; 3WCX A; 5INN A; 4B5G A; 4A9C A; 2A3Z B; 1ATN D; 4C1R A; 1DNK A; 4F1R A; 4GYZ A; 4PUQ A; 3U8U A; 5A7I A; 4F1H A; #chains in the Genus database with same CATH topology 3I48 A; 3G0R A; 5A7J A; 1E9N A; 2O3H A; 1DEW A; 5J3Z A; 5INK A; 4B5I A; 3I46 A; 4GZ2 A; 2DDT A; 4GZ1 A; 3G2C A; 4JG3 A; 4LND A; 4L20 A; 5J8N A; 3K55 A; 5EWT A; 2JC4 A; 3I41 A; 3NGN A; 3FZI A; 4CML A; 5INQ A; 3DNI A; 1WDU A; 2A41 B; 5J3S A; 2A42 B; 2J63 A; 4B5H A; 5DFF A; 5CFE A; 5HT2 A; 2EI9 A; 4GZ0 A; 2XSW A; 4L21 A; 5DG0 A; 3W2Y A; 3G00 A; 4F1H B; 4FVA A; 3G8V A; 5CFG A; 2DDR A; 1VYB A; 1DE8 A; 4B5J A; 4GEW A; 2VOA A; 3G3C A; 1BIX A; 5DFH A; 5DFJ A; 1I9Z A; 5INM A; 3MPR A; 1DE9 A; 2V0S A; 5INP A; 2ISI A; 3W2X A; 2DDS A; 4RUW A; 3N9V A; 3G0A A; 3W3D B; 3G6S A; 3G91 A; 3NR8 A; 4QH9 A; 1I9Y A; 4B5F A; 4CMN A; 2D1K B; 1HD7 A; 1Y21 A; 4L1Z A; 5J3P A; 3G3Y A; 5INO A; 3G38 A; 4AWN A; 4QHE A; 2A40 B; 3G2D A; 5INL A; 3GA6 A; 4F1I A; 2IMQ X; 3G1K A; 3L1W A; 1AKO A; 3CJC D; 1SR4 B; 4IEM A; 5DFI A; 3NGO A; 4QHD A; 4B5M A; 3NGQ A; 1SI6 X; 1YJH A; 4L1Y A; 3MTC A; 3G4T A; 2F1N A; 3TEB A; 3I5V A; 5DV4 A; 2O3C A; 5J42 A; 4K6L F; 2UYR X; 1NTF A; 5DV2 A; 2DNJ A; 4FPV A; 1ZWX A; 2JC5 A; 2F2F B; 2V0R A; 3WCX A; 5INN A; 4B5G A; 4A9C A; 2A3Z B; 1ATN D; 4C1R A; 1DNK A; 4F1R A; 4GYZ A; 4PUQ A; 3U8U A; 5A7I A; 4F1H A; #chains in the Genus database with same CATH homology 3I48 A; 3G0R A; 5A7J A; 1E9N A; 2O3H A; 1DEW A; 5J3Z A; 5INK A; 4B5I A; 3I46 A; 4GZ2 A; 2DDT A; 4GZ1 A; 3G2C A; 4JG3 A; 4LND A; 4L20 A; 5J8N A; 3K55 A; 5EWT A; 2JC4 A; 3I41 A; 3NGN A; 3FZI A; 4CML A; 5INQ A; 3DNI A; 1WDU A; 2A41 B; 5J3S A; 2A42 B; 2J63 A; 4B5H A; 5DFF A; 5CFE A; 5HT2 A; 2EI9 A; 4GZ0 A; 2XSW A; 4L21 A; 5DG0 A; 3W2Y A; 3G00 A; 4F1H B; 4FVA A; 3G8V A; 5CFG A; 2DDR A; 1VYB A; 1DE8 A; 4B5J A; 4GEW A; 2VOA A; 3G3C A; 1BIX A; 5DFH A; 5DFJ A; 1I9Z A; 5INM A; 3MPR A; 1DE9 A; 2V0S A; 5INP A; 2ISI A; 3W2X A; 2DDS A; 4RUW A; 3N9V A; 3G0A A; 3W3D B; 3G6S A; 3G91 A; 3NR8 A; 4QH9 A; 1I9Y A; 4B5F A; 4CMN A; 2D1K B; 1HD7 A; 1Y21 A; 4L1Z A; 5J3P A; 3G3Y A; 5INO A; 3G38 A; 4AWN A; 4QHE A; 2A40 B; 3G2D A; 5INL A; 3GA6 A; 4F1I A; 2IMQ X; 3G1K A; 3L1W A; 1AKO A; 3CJC D; 1SR4 B; 4IEM A; 5DFI A; 3NGO A; 4QHD A; 4B5M A; 3NGQ A; 1SI6 X; 1YJH A; 4L1Y A; 3MTC A; 3G4T A; 2F1N A; 3TEB A; 3I5V A; 5DV4 A; 2O3C A; 5J42 A; 4K6L F; 2UYR X; 1NTF A; 5DV2 A; 2DNJ A; 4FPV A; 1ZWX A; 2JC5 A; 2F2F B; 2V0R A; 3WCX A; 5INN A; 4B5G A; 4A9C A; 2A3Z B; 1ATN D; 4C1R A; 1DNK A; 4F1R A; 4GYZ A; 4PUQ A; 3U8U A; 5A7I A; 4F1H A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
