5DV2A

Crystal structure of human cnot6l in complex with cytidine-5'-monophosphate
Total Genus 117
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
117
sequence length
372
structure length
335
Chain Sequence
LPPRPWITLKERDSASFTVMCYNVLCDKYATRQLYGYCPSWALNWEYRKKGIMEEIVNCDADIISLQEVETEQYFTLFLPALKERGYDGFFSPKSRAKIMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFNQVAMANSDGSEAMLNRVMTKDNIGVAVVLEVHKELFKQLLIVANAHMHWDPEYSDVKLIQTMMFVSEVKNILEKASIPLVLCADLNSLPDSGVVEYLSNGGVADNHKDFKELRYNECLMNFSRITHGFQLKSAYENNLMPYTNYTFDFKGVIDYIFYSKTHMNVLGVLGPLDPQWLVENNITGCPHPHIPSDHFSLLTQLELHP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for inhibition of the deadenylase activity of human CNOT6L
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords CCR4-NOT transcription complex subunit 6-like
total genus 117
structure length 335
sequence length 372
ec nomenclature ec 3.1.13.4: Poly(A)-specific ribonuclease.
pdb deposition date 2015-09-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 5dv2A00
1SI6X 1ATND 4LNDA 3G3YA 3G3CA 2XSWA 3G0RA 4B5MA 2V0RA 2ISIA 4L1ZA 5DG0A 3G4TA 5INKA 2D1KB 5DFHA 2J63A 4F1HA 2F2FB 3G91A 1NTFA 3G1KA 5INPA 4GZ2A 5EWTA 2F1NA 4F1RA 4GZ1A 4B5HA 3MTCA 3NR8A 1I9ZA 3TEBA 3G00A 5DV4A 5INQA 4FPVA 5INLA 1VYBA 4PUQA 3WCXA 3W2XA 3G2CA 4B5GA 4L21A 4GYZA 1ZWXA 3G0AA 3MPRA 4GEWA 4QHDA 5J42A 5CFEA 5INOA 5INNA 3GA6A 2A3ZB 5J3SA 1DEWA 1DE9A 4F1IA 5INMA 3K55A 3I41A 4JG3A 5J3ZA 3N9VA 2JC4A 3G8VA 2V0SA 4B5IA 2O3CA 1I9YA 1Y21A 2EI9A 2O3HA 3NGQA 5DFJA 1AKOA 2UYRX 4CMNA 4F1HB 3G38A 2A41B 1E9NA 3G6SA 5A7IA 3FZIA 5HT2A 5DFIA 5J3PA 2DDSA 4RUWA 1DNKA 1BIXA 4IEMA 1SR4B 5DV2A 1HD7A 2DDRA 4C1RA 2A42B 5DFFA 4QHEA 3I5VA 5CFGA 2DDTA 1YJHA 3L1WA 4GZ0A 3I46A 2DNJA 5A7JA 2VOAA 3W3DB 4CMLA 4QH9A 3G2DA 4A9CA 5J8NA 1WDUA 3DNIA 3NGNA 4L1YA 1DE8A 2IMQX 4FVAA 4B5JA 4B5FA 2JC5A 3NGOA 3I48A 3W2YA 3CJCD 4K6LF 3U8UA 4AWNA 2A40B 4L20A
chains in the Genus database with same CATH superfamily
1SI6X 1ATND 4LNDA 3G3YA 3G3CA 2XSWA 3G0RA 4B5MA 2V0RA 2ISIA 4L1ZA 5DG0A 3G4TA 5INKA 2D1KB 5DFHA 2J63A 4F1HA 2F2FB 3G91A 1NTFA 3G1KA 5INPA 4GZ2A 5EWTA 2F1NA 4F1RA 4GZ1A 4B5HA 3MTCA 3NR8A 1I9ZA 3TEBA 3G00A 5DV4A 5INQA 4FPVA 5INLA 1VYBA 4PUQA 3WCXA 3W2XA 3G2CA 4B5GA 4L21A 4GYZA 1ZWXA 3G0AA 3MPRA 4GEWA 4QHDA 5J42A 5CFEA 5INOA 5INNA 3GA6A 2A3ZB 5J3SA 1DEWA 1DE9A 4F1IA 5INMA 3K55A 3I41A 4JG3A 5J3ZA 3N9VA 2JC4A 3G8VA 2V0SA 4B5IA 2O3CA 1I9YA 1Y21A 2EI9A 2O3HA 3NGQA 5DFJA 1AKOA 2UYRX 4CMNA 4F1HB 3G38A 2A41B 1E9NA 3G6SA 5A7IA 3FZIA 5HT2A 5DFIA 5J3PA 2DDSA 4RUWA 1DNKA 1BIXA 4IEMA 1SR4B 5DV2A 1HD7A 2DDRA 4C1RA 2A42B 5DFFA 4QHEA 3I5VA 5CFGA 2DDTA 1YJHA 3L1WA 4GZ0A 3I46A 2DNJA 5A7JA 2VOAA 3W3DB 4CMLA 4QH9A 3G2DA 4A9CA 5J8NA 1WDUA 3DNIA 3NGNA 4L1YA 1DE8A 2IMQX 4FVAA 4B5JA 4B5FA 2JC5A 3NGOA 3I48A 3W2YA 3CJCD 4K6LF 3U8UA 4AWNA 2A40B 4L20A
chains in the Genus database with same CATH topology
1SI6X 1ATND 4LNDA 3G3YA 3G3CA 2XSWA 3G0RA 4B5MA 2V0RA 2ISIA 4L1ZA 5DG0A 3G4TA 5INKA 2D1KB 5DFHA 2J63A 4F1HA 2F2FB 3G91A 1NTFA 3G1KA 5INPA 4GZ2A 5EWTA 2F1NA 4F1RA 4GZ1A 4B5HA 3MTCA 3NR8A 1I9ZA 3TEBA 3G00A 5DV4A 5INQA 4FPVA 5INLA 1VYBA 4PUQA 3WCXA 3W2XA 3G2CA 4B5GA 4L21A 4GYZA 1ZWXA 3G0AA 3MPRA 4GEWA 4QHDA 5J42A 5CFEA 5INOA 5INNA 3GA6A 2A3ZB 5J3SA 1DEWA 1DE9A 4F1IA 5INMA 3K55A 3I41A 4JG3A 5J3ZA 3N9VA 2JC4A 3G8VA 2V0SA 4B5IA 2O3CA 1I9YA 1Y21A 2EI9A 2O3HA 3NGQA 5DFJA 1AKOA 2UYRX 4CMNA 4F1HB 3G38A 2A41B 1E9NA 3G6SA 5A7IA 3FZIA 5HT2A 5DFIA 5J3PA 2DDSA 4RUWA 1DNKA 1BIXA 4IEMA 1SR4B 5DV2A 1HD7A 2DDRA 4C1RA 2A42B 5DFFA 4QHEA 3I5VA 5CFGA 2DDTA 1YJHA 3L1WA 4GZ0A 3I46A 2DNJA 5A7JA 2VOAA 3W3DB 4CMLA 4QH9A 3G2DA 4A9CA 5J8NA 1WDUA 3DNIA 3NGNA 4L1YA 1DE8A 2IMQX 4FVAA 4B5JA 4B5FA 2JC5A 3NGOA 3I48A 3W2YA 3CJCD 4K6LF 3U8UA 4AWNA 2A40B 4L20A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SI6 X;  1ATN D;  4LND A;  3G3Y A;  3G3C A;  2XSW A;  3G0R A;  4B5M A;  2V0R A;  2ISI A;  4L1Z A;  5DG0 A;  3G4T A;  5INK A;  2D1K B;  5DFH A;  2J63 A;  4F1H A;  2F2F B;  3G91 A;  1NTF A;  3G1K A;  5INP A;  4GZ2 A;  5EWT A;  2F1N A;  4F1R A;  4GZ1 A;  4B5H A;  3MTC A;  3NR8 A;  1I9Z A;  3TEB A;  3G00 A;  5DV4 A;  5INQ A;  4FPV A;  5INL A;  1VYB A;  4PUQ A;  3WCX A;  3W2X A;  3G2C A;  4B5G A;  4L21 A;  4GYZ A;  1ZWX A;  3G0A A;  3MPR A;  4GEW A;  4QHD A;  5J42 A;  5CFE A;  5INO A;  5INN A;  3GA6 A;  2A3Z B;  5J3S A;  1DEW A;  1DE9 A;  4F1I A;  5INM A;  3K55 A;  3I41 A;  4JG3 A;  5J3Z A;  3N9V A;  2JC4 A;  3G8V A;  2V0S A;  4B5I A;  2O3C A;  1I9Y A;  1Y21 A;  2EI9 A;  2O3H A;  3NGQ A;  5DFJ A;  1AKO A;  2UYR X;  4CMN A;  4F1H B;  3G38 A;  2A41 B;  1E9N A;  3G6S A;  5A7I A;  3FZI A;  5HT2 A;  5DFI A;  5J3P A;  2DDS A;  4RUW A;  1DNK A;  1BIX A;  4IEM A;  1SR4 B;  5DV2 A;  1HD7 A;  2DDR A;  4C1R A;  2A42 B;  5DFF A;  4QHE A;  3I5V A;  5CFG A;  2DDT A;  1YJH A;  3L1W A;  4GZ0 A;  3I46 A;  2DNJ A;  5A7J A;  2VOA A;  3W3D B;  4CML A;  4QH9 A;  3G2D A;  4A9C A;  5J8N A;  1WDU A;  3DNI A;  3NGN A;  4L1Y A;  1DE8 A;  2IMQ X;  4FVA A;  4B5J A;  4B5F A;  2JC5 A;  3NGO A;  3I48 A;  3W2Y A;  3CJC D;  4K6L F;  3U8U A;  4AWN A;  2A40 B;  4L20 A; 
#chains in the Genus database with same CATH topology
 1SI6 X;  1ATN D;  4LND A;  3G3Y A;  3G3C A;  2XSW A;  3G0R A;  4B5M A;  2V0R A;  2ISI A;  4L1Z A;  5DG0 A;  3G4T A;  5INK A;  2D1K B;  5DFH A;  2J63 A;  4F1H A;  2F2F B;  3G91 A;  1NTF A;  3G1K A;  5INP A;  4GZ2 A;  5EWT A;  2F1N A;  4F1R A;  4GZ1 A;  4B5H A;  3MTC A;  3NR8 A;  1I9Z A;  3TEB A;  3G00 A;  5DV4 A;  5INQ A;  4FPV A;  5INL A;  1VYB A;  4PUQ A;  3WCX A;  3W2X A;  3G2C A;  4B5G A;  4L21 A;  4GYZ A;  1ZWX A;  3G0A A;  3MPR A;  4GEW A;  4QHD A;  5J42 A;  5CFE A;  5INO A;  5INN A;  3GA6 A;  2A3Z B;  5J3S A;  1DEW A;  1DE9 A;  4F1I A;  5INM A;  3K55 A;  3I41 A;  4JG3 A;  5J3Z A;  3N9V A;  2JC4 A;  3G8V A;  2V0S A;  4B5I A;  2O3C A;  1I9Y A;  1Y21 A;  2EI9 A;  2O3H A;  3NGQ A;  5DFJ A;  1AKO A;  2UYR X;  4CMN A;  4F1H B;  3G38 A;  2A41 B;  1E9N A;  3G6S A;  5A7I A;  3FZI A;  5HT2 A;  5DFI A;  5J3P A;  2DDS A;  4RUW A;  1DNK A;  1BIX A;  4IEM A;  1SR4 B;  5DV2 A;  1HD7 A;  2DDR A;  4C1R A;  2A42 B;  5DFF A;  4QHE A;  3I5V A;  5CFG A;  2DDT A;  1YJH A;  3L1W A;  4GZ0 A;  3I46 A;  2DNJ A;  5A7J A;  2VOA A;  3W3D B;  4CML A;  4QH9 A;  3G2D A;  4A9C A;  5J8N A;  1WDU A;  3DNI A;  3NGN A;  4L1Y A;  1DE8 A;  2IMQ X;  4FVA A;  4B5J A;  4B5F A;  2JC5 A;  3NGO A;  3I48 A;  3W2Y A;  3CJC D;  4K6L F;  3U8U A;  4AWN A;  2A40 B;  4L20 A; 
#chains in the Genus database with same CATH homology
 1SI6 X;  1ATN D;  4LND A;  3G3Y A;  3G3C A;  2XSW A;  3G0R A;  4B5M A;  2V0R A;  2ISI A;  4L1Z A;  5DG0 A;  3G4T A;  5INK A;  2D1K B;  5DFH A;  2J63 A;  4F1H A;  2F2F B;  3G91 A;  1NTF A;  3G1K A;  5INP A;  4GZ2 A;  5EWT A;  2F1N A;  4F1R A;  4GZ1 A;  4B5H A;  3MTC A;  3NR8 A;  1I9Z A;  3TEB A;  3G00 A;  5DV4 A;  5INQ A;  4FPV A;  5INL A;  1VYB A;  4PUQ A;  3WCX A;  3W2X A;  3G2C A;  4B5G A;  4L21 A;  4GYZ A;  1ZWX A;  3G0A A;  3MPR A;  4GEW A;  4QHD A;  5J42 A;  5CFE A;  5INO A;  5INN A;  3GA6 A;  2A3Z B;  5J3S A;  1DEW A;  1DE9 A;  4F1I A;  5INM A;  3K55 A;  3I41 A;  4JG3 A;  5J3Z A;  3N9V A;  2JC4 A;  3G8V A;  2V0S A;  4B5I A;  2O3C A;  1I9Y A;  1Y21 A;  2EI9 A;  2O3H A;  3NGQ A;  5DFJ A;  1AKO A;  2UYR X;  4CMN A;  4F1H B;  3G38 A;  2A41 B;  1E9N A;  3G6S A;  5A7I A;  3FZI A;  5HT2 A;  5DFI A;  5J3P A;  2DDS A;  4RUW A;  1DNK A;  1BIX A;  4IEM A;  1SR4 B;  5DV2 A;  1HD7 A;  2DDR A;  4C1R A;  2A42 B;  5DFF A;  4QHE A;  3I5V A;  5CFG A;  2DDT A;  1YJH A;  3L1W A;  4GZ0 A;  3I46 A;  2DNJ A;  5A7J A;  2VOA A;  3W3D B;  4CML A;  4QH9 A;  3G2D A;  4A9C A;  5J8N A;  1WDU A;  3DNI A;  3NGN A;  4L1Y A;  1DE8 A;  2IMQ X;  4FVA A;  4B5J A;  4B5F A;  2JC5 A;  3NGO A;  3I48 A;  3W2Y A;  3CJC D;  4K6L F;  3U8U A;  4AWN A;  2A40 B;  4L20 A; 
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